Statins associate with better clinical outcomes in chronic hepatitis B patients with HBsAg seroclearanceArticle Published on 2021-08-012023-06-13 Journal: Hepatology international [Category] B형 간염, [키워드] Anti-HBs CHB HBV S-loss seroclearance statins [DOI] 10.1007/s12072-021-10197-4
Drug exposure may have a substantial influence on COVID-19 prognosis among residents of long-term care facilities: an exploratory analysis약물 노출은 장기 치료 시설 거주자들 사이에서 Covid-19 예후에 상당한 영향을 미칠 수 있습니다 : 탐색 적 분석Article Published on 2021-08-012022-08-31 Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 치료제, [키워드] ACE2 ACE2 inhibitors age association blockers Care carried Case fatality rate Comorbidities Comorbidity corticoid corticoids COVID-19 COVID-19 disease COVID-19 prognosis cross-sectional cross-sectional study death Diagnosis disease drug drug exposure Exploratory analysis Fatality rate females individual Inhaled inhaled corticoids inhibitor inhibitors intake Long-term care long-term care facilities LTC moment Platelet Prevalence prevalent Prognosis prognostic Propensity score protective factor risk factor SARS-CoV-2 SARS-COV-2 infection socio-demographic statins Vitamin Vitamin D [DOI] 10.1016/j.ijid.2021.07.007 PMC 바로가기 [Article Type] Article
Decreased Risk of Non-infectious Anterior Uveitis with Statin Therapy in a Large Healthcare Claims DatabaseArticle Published on 2021-07-272024-09-04 Journal: Graefe's Archive for Clinical and Experimental Oph [Category] 대상포진, [키워드] big data biostatistics Epidemiology statins Statistics Uveitis [DOI] 10.1007/s00417-021-05243-8 PMC 바로가기 [Article Type] Article
[Meta-analysis of the effects of statins on the risk of chronic liver disease and hepatocellular carcinoma]Meta-Analysis Published on 2021-07-202023-06-13 Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese [Category] B형 간염, [키워드] Chronic Liver Diseases Hepatocellular carcinoma Meta-analysis statins [DOI] 10.3760/cma.j.cn501113-20200311-00108 [Article Type] Meta-Analysis
A randomized open-label trial to evaluate the efficacy and safety of triple therapy with aspirin, atorvastatin, and nicorandil in hospitalised patients with SARS Cov-2 infection: A structured summary of a study protocol for a randomized controlled trialSARS Cov-2 감염으로 입원한 환자에서 아스피린, 아토르바스타틴, 니코란딜을 사용한 삼중 요법의 효능과 안전성을 평가하기 위한 무작위 공개 시험: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-07-152022-09-10 Journal: Trials [Category] SARS, 임상, [키워드] 1:1 ACHE Acute coronary syndrome Acute kidney injury acute renal failure adequate hydration adjuvant therapy Admission allergy ALT/AST Altered mental status Anti-inflammatory anticoagulation antipyretics Antithrombotic approved ARDS Aspirin AST/ALT atorvastatin bleeding Blinding block randomization Breastfeeding brown urine change characterized clinical clinical feature Clinical features Coagulopathy college Combination comorbid condition comorbid conditions comparator conducted control group coronary syndrome Corticosteroid Corticosteroids cough COVID-19 CPK creatine creatine kinase creatinine CRP current therapy Dexamethasone dissemination dose drug dysfunction Dyspnoea dysregulation effective Efficacy and safety element Endothelial dysfunction enrolled ethical committee evaluate excluded ferritin Fever followed by greater heparin hepatotoxicity Hospital admission hospital discharge Hospital mortality Hospital stay hospitalised patient Hospitalised patients hyperbilirubinemia hypoxia ICMR IEC immune dysregulation immunomodulatory impaired consciousness in-hospital mortality India Inflammation Inflammatory marker inflammatory markers Intervention intervention group intolerance intravenous Intravenous remdesivir invasive limit liver low molecular weight low molecular weight heparin management marker mechanical ventilation medication medications moderate muscle ache myalgia Myoglobin Myopathy myositis national guidelines Nicorandil Non-invasive number objective once daily Open-label open-label trial outcome oxygen Oxygen requirement oxygen support participant pathophysiologic pathophysiology Patient Platelet Platelet count Pneumonia positive Pregnancy Primary outcome progression protocol raised Rajendra Prasad Randomised control trial randomization randomize Randomized Randomized controlled trial randomly divided receive recruitment reducing mortality Registered registry Remdesivir renal failure reported respiratory rate rhabdomyolysis room air RT-PCR safety endpoint safety endpoints Sample size SARS-CoV-2 infected patient SARS-COV-2 infection Schematic screened Secondary outcomes Sepsis serum serum markers severe disease Shock significant interaction SpO2 Standard Standard of care starting dose statin statins Study design Study protocol substrates supplementary material Symptom Symptomatic treatment Tablet therapeutic therapeutic agent therapy thrombocytopenia Treatment Trial Trial registration two-arm parallel ULN Urine weakness website [DOI] 10.1186/s13063-021-05361-y PMC 바로가기 [Article Type] Letter
Statins and clinical outcomes in hospitalized COVID-19 patients with and without Diabetes Mellitus: a retrospective cohort study with propensity score matchingObservational Study Published on 2021-07-102022-10-04 Journal: Cardiovascular Diabetology [Category] 임상, [키워드] 1:1 95% CI administration appear association atorvastatin Clinical outcome Cohort conducted confounder COVID-19 COVID-19 diagnosis COVID-19 patient COVID-19 patients determine Diabetes Mellitus disease group Hospitalization hospitalized COVID-19 patient hospitalized COVID-19 patients hospitalized patient Inpatient intensive care mechanical ventilation medication Mortality multivariable multivariable analysis outcome Patient patients pleiotropic effect Primary outcome propensity score matching pursuit race randomized clinical trial reduce reduced reduction in mortality regression analysis Research design Result retrospective cohort study Safe severe disease severity of COVID-19 statin statins subgroup analysis supplementary material Support [DOI] 10.1186/s12933-021-01336-0 PMC 바로가기 [Article Type] Observational Study
The vicious cycle: a history of obesity and COVID-19Commentary Published on 2021-07-062022-10-27 Journal: BMC Public Health [Category] COVID-19, [키워드] ACE2 Angiotensin-converting enzyme blocker cardiometabolic changes confirmed case coronavirus Coronavirus disease-related cardiometabolic syndrome COVID-19 COVID-19 diagnosis COVID-19 patients death drug evaluate GLP-1 glycemic control High-processed food higher risk Hospitalization implication obesity observational study outcomes pandemic pathway Prognostic marker Prospective Study receptor Regulation SARS-CoV-2 Stage statins subject syndrome with COVID-19 [DOI] 10.1186/s12872-021-02134-y PMC 바로가기 [Article Type] Commentary
Cardiac manifestations of the coronavirus disease-19: a review of pathogenesis, clinical manifestations, diagnosis, and treatment코로나 바이러스 질병의 심장 증상 -19 : 병인, 임상 증상, 진단 및 치료의 검토Review Published on 2021-07-062022-09-10 Journal: The Pan African Medical Journal [Category] MERS, SARS, 바이오마커, [키워드] Acute kidney injury acute respiratory distress acute respiratory distress syndrome AKI Anti-viral therapy approach ARDS best Biomarker cardiac cardiac complication Cardiac complications Cardiomyopathies cardiovascular cardiovascular disease caused Chest chest pain chest tightness clinical manifestations coronavirus coronavirus disease Coronavirus disease-19 COVID-19 COVID-19 patient CVD D-dimer Diagnosis dimer disease drugs ECG Effective strategies effective strategy electrocardiogram fibrinogen healthcare worker heart failure hemodynamic Hemodynamic monitoring IL-6 IL-6 blockers Inflammatory marker inflammatory markers Liver damage manifestation manifested morbidity and mortality myocarditis N-terminal NT-proBNP pandemic Pathogenesis peptide performed Pneumonia pro-B-type natriuretic peptide reduce Research respiratory respiratory distress SARS-CoV-2 Septic shock Severe acute respiratory syndrome severe cases statins supportive care syndrome telemetry thrombolytic tissue Treatment troponin Wuhan Wuhan, China [DOI] 10.11604/pamj.2021.39.173.27802 PMC 바로가기 [Article Type] Review
Coronaviruses, cholesterol and statins: Involvement and application for Covid-19Review Published on 2021-06-182023-06-15 Journal: Biochimie [Category] MERS, SARS, [키워드] cholesterol coronavirus COVID-19 Drug repurposing Membrane microdomains statins [DOI] 10.1016/j.biochi.2021.06.005 PMC 바로가기 [Article Type] Review
Statins in COVID-19 TherapyReview Published on 2021-06-162022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] antioxidant antiviral therapy atherosclerotic plaque cardiac cardiovascular disease cardiovascular risk clinical trial COVID-19 COVID-19 therapy Cytokine storm de novo drug Effect Endothelial dysfunction European group host cells Inflammatory responses pathophysiology Patient patients with COVID-19 pleiotropic Pleiotropic effects respiratory infections SARS-CoV-2 statin statins therapy thrombosis Treatment [DOI] 10.3390/life11060565 PMC 바로가기 [Article Type] Review