Strong Association of Angiotensin Converting Enzyme-2 Gene Insertion/Deletion Polymorphism with Susceptibility to SARS-CoV-2, Hypertension, Coronary Artery Disease and COVID-19 Disease MortalityArticle Published on 2021-10-272022-10-30 Journal: Journal of Personalized Medicine [Category] COVID-19, [키워드] 95% CI ACE ACE gene ACE1-angiotensin-converting enzyme 1 ACE2 ACE2-angiotensin-converting enzyme 2 addition advanced age age allele allelic amplification Analysis angiotensin angiotensin-converting enzyme 2 Artery association bind Control controls Coronary Coronary artery disease correlation COVID-19 COVID-19 mortality COVID-19 patient COVID-19 patients COVID-19 severity diabete distribution facilitate Frequency functional Gender gene polymorphism Genotype genotyping group Health healthy control host cell hypertension I/D I/D polymorphism indicated Infection insertion/deletion International ischemic heart disease Mortality Mutation outbreak P -value Pathogenesis pathogenesis of COVID-19 PCR protective factor public health receptor reported Result rs4240157 SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome coronavirus 2 severe COVID-19 severity significant difference Spike protein Strong susceptibility to SARS-CoV-2 susceptible T2D targeted intervention virus entry with COVID-19 [DOI] 10.3390/jpm11111098 PMC 바로가기 [Article Type] Article
The Upper Respiratory Tract of Felids Is Highly Susceptible to SARS-CoV-2 InfectionFelids의 상부 호흡기는 SARS-CoV-2 감염에 매우 취약합니다Article Published on 2021-09-302022-09-10 Journal: International Journal of Molecular Sciences [Category] SARS, 진단, 치료기술, [키워드] ACE2 ACE2 expression air–liquid interface Cell Cell culture cultures detection epithelial cell epithelial cells Ex vivo felines highlight Human Infection inoculated less lion lung Lungs nasal mucosa natural nose pathological changes predatory primary cell primary cell cultures question replicate Replication respiratory respiratory tract risk SARS-CoV-2 SARS-COV-2 infection Strong susceptibility susceptible tissue Trachea tracheal tract upper upper respiratory tract Viral viral replication virus transmission [DOI] 10.3390/ijms221910636 PMC 바로가기 [Article Type] Article
BNT162b2 Vaccination Elicits Strong Serological Immune Responses Against SARS-CoV-2 Including Variants of Concern in Elderly ConvalescentsBNT162b2 백신 접종은 노인 요양기의 우려 변종을 포함하여 SARS-CoV-2에 대한 강력한 혈청학적 면역 반응을 이끌어냅니다Observational Study Published on 2021-09-292022-09-11 Journal: Frontiers in Immunology [Category] SARS, 변종, 임상, 진단, [키워드] Against age analyzed anti-Spike IgG Antibody titer Antibody titers B.1.1.7 B.1.351 benefit binding domain BNT162b2 Care Comirnaty concern convalescent individual COVID-19 COVID-19-convalescent individual cross-reactive Efficacy elderly End End points Gender IgA titer IgA titers IgG titers immune response immune responses Including individual Long-term care MOST mRNA vaccine mutated neutralization capacity neutralization test Neutralizing neutralizing capacity P.1 pre-vaccination prospective observational cohort response SARS-CoV-2 SARS-CoV-2 receptor serological serum significantly higher strength Strong subject vaccination Vaccine vaccinees variants of concern VOCs [DOI] 10.3389/fimmu.2021.743422 PMC 바로가기 [Article Type] Observational Study
Health Information Systems in the COVID-19 Pandemic: A Short Survey of Experiences and Lessons Learned From the European RegionPublic Health Published on 2021-09-282022-10-31 Journal: Frontiers in Public Health [Category] Coronavirus, MERS, SARS, [키워드] Administered arising Asian Belgium country COVID – 19 COVID-19 COVID-19 crisis COVID-19 pandemic Critical Croatia Czech Republic data Epidemics ethical standards European experience Federation Government Greece health data health information Health information system highest Iceland identify implementation information initiative Ireland Italy Kazakhstan lack Latvia lesson Lessons learned Lithuania member network pandemic promote provide public health Region required Romania state Strong Support survey System the WHO Turkey United Kingdom [DOI] 10.3389/fpubh.2021.676838 PMC 바로가기 [Article Type] Public Health
The Depression Anxiety Stress Scale 21: Development and Validation of the Depression Anxiety Stress Scale 8-Item in Psychiatric Patients and the General Public for Easier Mental Health Measurement in a Post COVID-19 WorldArticle Published on 2021-09-272022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] age and gender Alpha Anxiety Arab Arabic assessment ceiling effect CFA CFI Clinical practice comparable conditions confinement period confirmatory factor analysis coronavirus disease 2019/COVID-19 Coverage COVID-19 DASS-21 DASS-8 Depression Depression Anxiety Stress Scales-21/DASS-21 development diagnosed discriminant validity disorder effort examined expressed Factor factorial structure/psychometric properties/structural validity/validation FIVE good predictive validity groups highest Inclusion individual internal consistency item coverage measure measurement measurement invariance/multigroup analysis Patient positive correlation Predictive Psychiatric Psychiatric disorders Psychological distress psychometric property psychopathologies Public questionnaire Research Saudi Arabia shortened version* shorter version* of the DASS-21 Spearman’s correlation Stress Scale Strong Structure Support validation Validity were used [DOI] 10.3390/ijerph181910142 PMC 바로가기 [Article Type] Article
COVID-19 pandemic containment in the Caribbean Region: A review of case-management and public health strategiesReview Published on 2021-09-272022-10-27 Journal: AIMS Public Health [Category] COVID-19, [키워드] acute respiratory distress ARDS Caribbean China clinical manifestation clinical manifestations confirmed case cough country COVID-19 COVID-19 case COVID-19 pandemic Diagnosis effective Epidemiology Fever Health health system initial malaise management measure Measures mild case pandemic Perspective provided Public public health quarantine severe cases Shock Spread Strong Surveillance syndrome Transmission triggering Vaccine World Health Organization Wuhan [DOI] 10.3934/publichealth.2021053 PMC 바로가기 [Article Type] Review
Why Does the SARS-CoV-2 Delta VOC Spread So Rapidly? Universal Conditions for the Rapid Spread of Respiratory Viruses, Minimum Viral Loads for Viral Aerosol Generation, Effects of Vaccination on Viral Aerosol Generation, and Viral Aerosol CloudsSARS-CoV-2 Delta VOC가 그렇게 빠르게 확산되는 이유는 무엇입니까? 호흡기 바이러스의 급속한 확산을 위한 보편적 조건, 바이러스 에어로졸 생성을 위한 최소 바이러스 부하, 바이러스 에어로졸 생성 및 바이러스 에어로졸 구름에 대한 백신 접종의 영향Communication Published on 2021-09-172022-09-10 Journal: International Journal of Environmental Research an [Category] SARS, 변종, [키워드] activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition aerosol Aerosol generation aerosol transmission Aerosols air infection Airborne transmission Alpha Alpha variant Alpha VOC Analysis assumed Asymptomatic average B.1.1.7 B.1.617.2 binding affinity bioaerosol cloud condition conditions contagious disease contribute coronavirus coronavirus disease country COVID-19 COVID-19 vaccination Cutoff decrease delta variant Delta VOC Effect environmental monitoring experimental results explain generate Generation high viral load Host hosts human cells Infection load minimum Nosocomial infection novel pandemic Particle Rapid reducing reported required respiratory respiratory fluid respiratory particle respiratory viruses resulting SARS-CoV-2 SARS-CoV-2 bioaerosol SARS-CoV-2 variant of concern severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spread stability Strong symptom onset the SARS-CoV-2 Transmission Universal vaccination variant Viral viral aerosol cloud viral cloud viral infection Viral load virus virus transmission viruses VoC [DOI] 10.3390/ijerph18189804 PMC 바로가기 [Article Type] Communication
High-Frequency, High-Throughput Quantification of SARS-CoV-2 RNA in Wastewater Settled Solids at Eight Publicly Owned Treatment Works in Northern California Shows Strong Association with COVID-19 IncidenceResearch Article Published on 2021-09-142022-10-29 Journal: mSystems [Category] COVID-19, [키워드] access acute respiratory syndrome Analysis can be used collected Community comparable Concentration conducted coronavirus coronavirus disease correlated COVID-19 COVID-19 cases COVID-19 incidence Critical demonstrated detect detectable effort eight Epidemiology generate High-resolution Implementing incidence of COVID-19 incidence rate increase in infectious disease outbreak lab Laboratory log Mild normalized pathogen plant producing Prospective Study provided Result Retrospective study RNA RNA concentration Sample SARS-CoV-2 SARS-CoV-2 RNA Settled solids show Solid Strong Transmission Treatment Urine virus wastewater website with COVID-19 work [DOI] 10.1128/mSystems.00829-21 PMC 바로가기 [Article Type] Research Article
Development of in-house, indirect ELISAs for the detection of SARS-CoV-2 spike protein-associated serology in COVID-19 patients in Panama파나마의 COVID-19 환자에서 SARS-COV-2 스파이크 단백질 관련 혈청학의 검출을위한 사내, 간접 ELISA의 개발Research Article Published on 2021-09-142022-09-10 Journal: PLoS ONE [Category] 진단, 치료기술, [키워드] acute respiratory disease Analysis analyzed antibodies Antigen antigens AUC caused comparison confirmation Contact contact with coronavirus COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients Cross reactivity Cutoff Definition detect development diagnostic diagnostic test effective ELISA ELISA assay estimation evaluate fragment health authorities Health authority Human IgG IgG and IgM IgM IgM antibodies IMPROVE MERS morbidity Mortality Multiple multiple comparisons name New coronavirus new coronavirus SARS-CoV-2 no significant difference OD values outbreak p values parameter PCR produced Protein reactivity real time real time PCR receiver operating characteristic Receptor binding domain Respiratory disease reverse transcriptase RT-PCR RT-PCR test SARS-CoV-2 SARS-CoV-2 spike sensitivity serology Seroprevalence serum sample specificity spike Spike protein Strong symptomatic individual symptomatic individuals the antibody Viral viral antigens Viral RNA viral spike protein virus [DOI] 10.1371/journal.pone.0257351 PMC 바로가기 [Article Type] Research Article
Reliable and Interpretable Mortality Prediction With Strong Foresight in COVID-19 Patients: An International Study From China and GermanyArtificial Intelligence Published on 2021-09-032022-10-31 Journal: Frontiers in Artificial Intelligence [Category] COVID-19, [키워드] Accuracy Admission Analysis applied approach association AUC build C-reactive protein China clinical feature Clinical features Cohort cohorts collected COVID-19 COVID-19 patient COVID-19 patients demonstrated Diseases FIVE foresight Germany hospital independent Infection International interpretability lactate dehydrogenase lymphocyte Mortality mortality prediction model neutrophil count Patient patients with COVID-19 performed prediction Predictive predictive power progression reliability resource resulting robust Strong Treatment Würzburg cohort Wuhan Wuhan cohort α-Hydroxybutyrate dehydrogenase [DOI] 10.3389/frai.2021.672050 PMC 바로가기 [Article Type] Artificial Intelligence