VEGF – Page 5 – Communicable Diseases Research

COVID-19: Direct and Indirect Mechanisms of Statins

Review

Published on 2021-04-172022-10-29
Journal: International Journal of Molecular Sciences [Category] COVID-19, MERS, SARS,

Potential Mechanism Prediction of Herbal Medicine for Pulmonary Fibrosis Associated with SARS-CoV-2 Infection Based on Network Analysis and Molecular Docking

Pharmacology

Published on 2021-04-122022-10-31
Journal: Frontiers in Pharmacology [Category] COVID-19,

[키워드] analyses Analysis approach binding activity CCP Chinese Chinese herbal medicine component components contribute COVID-19 database distribution enrichment analysis exhibited expression finding Gene ontology health-care Herbal high risk IL-6 include indicated Infection inhibit involved KEGG Kyoto MAPK MAPK signaling mechanism Medicine metabolism MMP9 molecular docking molecular mechanism molecular mechanisms multiple pathways network network pharmacology offer pathway Patient Potential PPI predict prediction prescription protein-protein interaction pulmonary pulmonary fibrosis receptor SARS-CoV-2 SARS-COV-2 infection signaling pathway signaling pathways suggested target targets TGF-β1 the disease the SARS-CoV-2 TNF-α treatment for COVID-19 VEGF Version
[DOI] 10.3389/fphar.2021.602218 PMC 바로가기 [Article Type] Pharmacology

Plasma biomarker profiling of PIMS-TS, COVID-19 and SARS-CoV2 seropositive children – a cross-sectional observational study from southern India.

PIMS-TS, COVID-19 및 SARS-CoV2 혈청양성 아동의 혈장 바이오마커 프로파일링 - 인도 남부의 횡단면 관찰 연구.

Observational Study

Published on 2021-04-022022-08-31
Journal: EBioMedicine [Category] MERS, 바이오마커, 유전자 메커니즘, 임상,

[키워드] acute COVID-19 Analysis Biomarker Care CCL11 CCL19 CCL2 CCL20 CCL5 chemokine chemokines Chennai children Children's Hospital clinical phenotype clinical phenotypes conditions controls correlated country COVID-19 COVID-19 infection cross-sectional CRP CXCL10 cytokine Cytokine storm Cytokines elevated finding GM-CSF granzyme granzyme B growth factor Growth factors hospital Hyperinflammatory IFNα IFNβ IFNγ IL-1 IL-10 IL-15 IL-17A IL-1α IL-2 IL-33 IL-6 immune India Infection Inflammatory lymphocyte Lymphocyte count management MIS-C multiplex negative correlation paediatric inflammatory multisystem syndrome Pathogenesis performed PIMS PIMS-TS plasma biomarker positive correlation presenting pro-inflammatory cytokines SARS-CoV-2 SARS-COV-2 infection SARS-CoV2 seropositive significantly sodium sodium levels syndrome TNFα trajectory unique VEGF
[DOI] 10.1016/j.ebiom.2021.103317 PMC 바로가기 [Article Type] Observational Study

Comparison of VEGF-A values between pregnant women with COVID-19 and healthy pregnancies and its association with composite adverse outcomes

Article

Published on 2021-04-012023-07-12
Journal: Journal of medical virology [Category] SARS,

[키워드] adverse outcome COVID-19 Pregnancy SARS-CoV-2 VEGF
[DOI] 10.1002/jmv.26631

COVID-19 engages clinical markers for the management of cancer and cancer-relevant regulators of cell proliferation, death, migration, and immune response

COVID-19는 암 관리 및 세포 증식, 사멸, 이동 및 면역 반응의 암 관련 조절자를 위한 임상 마커를 사용합니다.

Article

Published on 2021-03-042022-08-31
Journal: Scientific Reports [Category] SARS, 바이오마커, 치료법,

[키워드] biological processe biological processes Cancer cancer patient Cancer patients Cancer therapy Cell cell proliferation clinical clinical decision clinical marker clinical markers clinical observations COVID-19 death Diagnosis diagnostic Diversity EGF endothelial engage Engagement epidemiological epithelial FGF immune response immune system immune system cells infected with SARS-CoV-2 initiated Intersection management marker mechanism Migration modifications network network analysis observation pathway Pathways predicted Prognosis provide rationale regulator Regulatory Regulatory networks retrieved SARS-CoV-2 smooth muscle Support Symptom TGFβ Treatment Tumor tumor suppressors tumorigenesis understanding VEGF virus was used
[DOI] 10.1038/s41598-021-84780-y PMC 바로가기 [Article Type] Article

Network analysis and molecular mapping for SARS-CoV-2 to reveal drug targets and repurposing of clinically developed drugs

SARS-CoV-2에 대한 네트워크 분석 및 분자 매핑을 통해 약물 표적을 밝히고 임상적으로 개발된 약물의 용도 변경

Article

Published on 2021-03-012022-08-31
Journal: Virology [Category] MERS, SARS, 신약개발, 유전자 메커니즘, 치료제,

[키워드] (hydroxychloroquine) Analysis Antibiotics antimalarial antiretroviral Azithromycin BCL-2 biological process carried chemokine Chemokine receptor clinically Combination coronavirus dietary supplement dietary supplements disease networks docking docking analysis docking study drug drug combination Drug repurposing drug target effective EGFR ErbB Estrogen event FoxO global pandemic GnRH HIF-1 host inflammatory response Hydroxychloroquine IL-17 insulin Interaction involved Jak-STAT KEGG pathway analysis life cycle Lopinavir LOPINAVIR AND RITONAVIR MAPK modulation molecular molecular docking molecular mechanism morbidity and mortality mortality rate multiple pathway multiple pathways network Neurotrophin novel Novel coronavirus Ontology PARP pathway platelet activation predict PRKCB Process analysis receptor reduce Ritonavir SARS-CoV-2 SARS–CoV–2. signaling pathway STAT suggested target targets thyroid hormone TNF Toll-like receptor Treatment VEGF Viral viral infection viral infectivity viral life cycle viral replication virus Vitamin Vitamin C
[DOI] 10.1016/j.virol.2020.12.006 PMC 바로가기 [Article Type] Article

Synthetic Messenger RNA-Based Vaccines: From Scorn to Hype

합성 메신저 RNA 기반 백신: 경멸에서 과장으로

Review

Published on 2021-02-092022-09-01
Journal: Viruses [Category] MERS, 진단,

Efficacy and tolerability of bevacizumab in patients with severe Covid-19

중증 코로나19 환자에서 베바시주맙의 효능 및 내약성

Clinical Trial

Published on 2021-02-052022-08-13
Journal: Nature Communications [Category] MERS, 임상, 진단, 치료법, 치료제,

[키워드] ambient anti-vascular Anti-vascular endothelial growth factor bevacizumab bevacizumab plus standard care body temperature changes Chest computed tomography chest imaging China Clinical efficacy clinical trial comparable Computed tomography conducted control group Controlled trial controls COVID-19 patient COVID-19 patients discharged Drug development endothelial Fever fraction growth factor IMPROVE improving oxygenation inspiration Italy lesion areas/ratio mmHg NCT04275414 oxygen oxygen pressure oxygen saturation oxygen-support status Oxygenation PaO partial arterial oxygen pressure Patient patients Pneumonia pulmonary pathological Randomized controlled trial recruited reduction relative respiratory rate SARS-CoV-2 severe COVID-19 shortening oxygen-support duration shown Significant single-arm single-arm trial standard care Tolerability Treatment Vascular vascular changes VEGF viral infection X-ray
[DOI] 10.1038/s41467-021-21085-8 PMC 바로가기 [Article Type] Clinical Trial

The mechanism and active compounds of semen armeniacae amarum treating coronavirus disease 2019 based on network pharmacology and molecular docking

Original Article

Published on 2021-02-042022-10-31
Journal: Food & Nutrition Research [Category] COVID-19,

[키워드] 3CLpro ACE2 amygdalin AutoDock binding activity biological processes caspase-3 cellular component Chinese Clinical practice collected component Compound coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 Cytoscape database DAVID disease Disease network dissemination docking Effect EGFR eight endothelial enrichment analysis enzyme II epidermal GeneCards growth factor HRAS IL6 immunofluorescence indicated Inflammatory Injury Interaction KEGG Kyoto lung Lung inflammation MAPK MAPK1 MAPK3 mechanism mice modulating molecular docking molecular functions molecular mechanism network analysis network pharmacology nine objective OMIM Ontology outbreak pathway Pathways PPI Prevent protease Protein PubChem database public health receptor regulated Result retrieved SARS-CoV-2 Semen semen armeniacae amarum significantly increased SRC suggested target target prediction TCM TCMSP threat Transcription treated treating COVID-19 Treatment TTD Vascular VEGF VEGFA virus was used Western blot analysis
[DOI] 10.29219/fnr.v65.5623 PMC 바로가기 [Article Type] Original Article

Anti-VEGF intravitreal injections in the era of COVID-19: responding to different levels of epidemic pressure

Review Article

Published on 2021-02-022022-10-31
Journal: Graefe's Archive for Clinical and Experimental Oph [Category] COVID-19, MERS, SARS,

[키워드] Academy analyzed anti-vascular Anti-VEGF Clinical practice Clusters complex Consensus Consistency coronavirus country COVID-19 COVID-19 case COVID-19 pandemic endothelial Epidemic First wave growth factor Guidance healthcare Healthcare system hygiene infection rate International intravitreal intravitreal injection less Local measure Measures National Ophthalmologist ophthalmology pandemic Patient patients Personal protective equipment physical distancing receive receiving recommendation recommendations reduce regimen required resource Result Retinal disease risk Spread steering committee strained Treatment VEGF vision Vision Academy
[DOI] 10.1007/s00417-021-05097-0 PMC 바로가기 [Article Type] Review Article