waning immunity – Page 5 – Communicable Diseases Research

Modeling waning and boosting of COVID-19 in Canada with vaccination

예방 접종으로 캐나다의 COVID-19 감소 및 증가 모델링

Article

Published on 2022-06-012022-09-11
Journal: Epidemics [Category] COVID19(2023년), SARS, 변종,

SARS-CoV-2 reinfections: Overview of efficacy and duration of natural and hybrid immunity

SARS-CoV-2 재감염: 자연 면역 및 잡종 면역의 효능 및 기간 개요

Review

Published on 2022-06-012022-09-11
Journal: Environmental research [Category] COVID19(2023년), SARS, 변종,

COVID-19 vaccine booster dose needed to achieve Omicron-specific neutralisation in nursing home residents

요양원 거주자에서 Omicron-specific 중화를 달성하는 데 필요한 COVID-19 백신 부스터 용량

Article

Published on 2022-06-012022-09-11
Journal: EBioMedicine [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술,

[키워드] anti-RBD Anti-spike binding domain BNT162b2 BNT162b2 mRNA BNT162b2 mRNA vaccine booster booster dose booster vaccination CDC COVID-19 COVID-19 vaccine death detectable dose enrolled Evidence examined Geriatrics HCW HCWs healthcare worker Healthcare workers high-risk population Hope hospitalisation Humoral immunity initial lifted limit of detection Long-term care majority median age morbidity and mortality mRNA vaccine neutralisation neutralisation activity neutralisation titre Neutralisation titres Neutralising activity NIH nursing home omicron Omicron variant PROTECT RBD SARS-CoV-2 SARS-COV-2 infection significantly increased Support These data titre vaccination variant variants vulnerable population waning immunity Wuhan strain
[DOI] 10.1016/j.ebiom.2022.104066 PMC 바로가기 [Article Type] Article

Development and evaluation of a machine learning-based in-hospital COVID-19 disease outcome predictor (CODOP): A multicontinental retrospective study

기계 학습 기반 병원 내 COVID-19 질병 결과 예측기(CODOP) 개발 및 평가: 다대륙 후향적 연구

Article

Published on 2022-05-172022-09-11
Journal: eLife [Category] COVID19(2023년), SARS, 변종, 치료기술,

[키워드] allocation AUROC breakthrough infections calibrated Clinical outcome clinical parameter clinical utility clinically Cohort cohort of patient Computational biology country COVID-19 COVID-19 disease COVID-19 patient deaths development disperse effective heterogeneous hospital Hospital admission hospital resources Hospitalization hospitalizations hospitalized COVID-19 patients Human In-hospital Latin Latin America machine-learning maintain Medicine New offer outcome pandemic patient cohort patient cohorts prediction Predictive Retrospective study risk stratification SARS-CoV-2 variants sensitivity Spain specificity Systems biology tested Triage USA vaccination vaccination rate Vaccination Status variant virus waning immunity
[DOI] 10.7554/eLife.75985 PMC 바로가기 [Article Type] Article

Intranasal administration of a recombinant RBD vaccine induces long-term immunity against Omicron-included SARS-CoV-2 variants

재조합 RBD 백신의 비강내 투여는 오미크론이 포함된 SARS-CoV-2 변이체에 대한 장기 면역을 유도합니다

Article

Published on 2022-05-172022-09-11
Journal: Signal Transduction and Targeted Therapy [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 administration booster Cell coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 deficiency demonstrated Economy effective vaccine Emergency global health Health IgG antibody immune response immune responses Immunity immunization induce intramuscularly intranasal Local long-lasting lung lymph nodes memory T cell memory T cells mice Migration mucosal mutant strain Neutralizing omicron Omicron variants outbreak persistence proliferation protective immunity RBD required respiratory robust SARS-CoV-2 SARS-CoV-2 variant secretory IgA sera Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus Strains Strong suggested systemically T cells T-cell threat Vaccine vaccine candidate Vaccines variant variants waning immunity wild-type
[DOI] 10.1038/s41392-022-01002-1 PMC 바로가기 [Article Type] Article

A multitope SARS-CoV-2 vaccine provides long-lasting B cell and T cell immunity against Delta and Omicron variants

멀티토프 SARS-CoV-2 백신은 Delta 및 Omicron 변이체에 대해 오래 지속되는 B 세포 및 T 세포 면역을 제공합니다

Clinical Trial

Published on 2022-05-162022-09-11
Journal: The Journal of Clinical Investigation [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단, 치료기술, 치료법,

[키워드] adverse event Antibody titers Asia B cell booster Breakthrough infection breakthrough infections center conducted conserved Control COVID-19 cross-reactive cytotoxic T lymphocyte Delta disease control dose elicited epitope Epitopes evaluated fatigue healthy helper T cell Heterologous human convalescent sera Immunity immunization immunogenicity Inc. injection site pain long-lasting lymphocyte membrane memory immunity Mild Ministry of Health Neutralizing antibodies Neutralizing antibody titer neutralizing antibody titers Neutralizing titer nucleocapsid omicron Omicron variants peptide peptides Phase I placebo-controlled Protein provide Randomized representing responsible safety profile sarbecovirus SARS-CoV-2 vaccine SARS-CoV-2 variant SARS-CoV-2 variants second dose Serious Adverse Event Serious Adverse Events subunit Subunit vaccine T cell Taiwan Trial trials Vaccine variant variants of SARS-CoV-2 virus-neutralizing antibody VOCs waning immunity Welfare were recorded
[DOI] 10.1172/JCI157707 PMC 바로가기 [Article Type] Clinical Trial

SARS-CoV-2 vaccine effectiveness against infection, symptomatic and severe COVID-19: a systematic review and meta-analysis

감염, 증상 및 중증 COVID-19에 대한 SARS-CoV-2 백신 효과: 체계적인 검토 및 메타 분석

Meta-Analysis

Published on 2022-05-072022-09-11
Journal: BMC Infectious Diseases [Category] Coronavirus, COVID19(2023년), SARS, 변종,

[키워드] 95% CI Ad26 Ad26.COV2.S age approach assessment booster vaccination can be used certainty Cohort studies cohort study completion Controlled controlled trials coronavirus disease COVID-19 database declined defined dependent on development Effectiveness Efficacy Evidence Evolution Evolution of SARS-CoV-2 FIVE Health Organization Immunity individual individuals Infection literature Meta-analysis outcome Primary outcomes public health random-effects model Randomized controlled trial remained representing Risk of bias SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 vaccine searched selected severe COVID-19 symptomatic symptomatic COVID-19 systematic review systematic reviews These data vaccination Vaccine vaccine effectiveness variant variants virus waned waning immunity was performed was used World Health Organization
[DOI] 10.1186/s12879-022-07418-y PMC 바로가기 [Article Type] Meta-Analysis

Neutralizing antibody responses 300 days after SARS-CoV-2 infection and induction of high antibody titers after vaccination

SARS-CoV-2 감염 300일 후 항체 반응 중화 및 백신 접종 후 고항체 역가 유도

Article

Published on 2022-05-012022-09-11
Journal: European Journal of Immunology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술,

[키워드] absence Anti-RBD antibodies Anti-RBD antibody antibody antibody level antibody levels Antibody Response Antibody titer Antibody titers Antibody-mediated immunity benefit COVID-19 COVID-19 patient COVID-19 patients COVID-19 vaccination declined detect detectable disease health institution Immunity individual individuals Infection Local Neutralizing antibodies neutralizing antibody Neutralizing antibody titer outbreak PROTECT RBD Receptor binding domain SARS-CoV-2 SARS-CoV-2 ⋅ COVID-19 ⋅ Vaccines ⋅ antibody titers ⋅ waning immunity. SARS-COV-2 infection SARS-CoV-2 spike spike These data vaccinated individual vaccination vaccine dose virus waning immunity
[DOI] 10.1002/eji.202149758 PMC 바로가기 [Article Type] Article

Hospitalised patients with breakthrough COVID-19 following vaccination during two distinct waves in Israel, January to August 2021: a multicentre comparative cohort study

2021년 1월부터 8월까지 이스라엘에서 두 차례에 걸쳐 백신 접종 후 획기적인 COVID-19로 입원한 환자: 다기관 비교 코호트 연구

Multicenter Study

Published on 2022-05-012022-09-11
Journal: Eurosurveillance [Category] COVID19(2023년), SARS, 변종,

An analysis of antibody response following the second dose of CoronaVac and humoral response after booster dose with BNT162b2 or CoronaVac among healthcare workers in Turkey

터키 의료 종사자의 코로나백 2차 접종 후 항체 반응 및 BNT162b2 또는 코로나백 추가 접종 후 체액성 반응 분석

Article

Published on 2022-05-012022-09-11
Journal: Journal of medical virology [Category] Fulltext, MERS, 변종, 진단,

[키워드] 95% CI 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration age Analysis Anti-RBD IgG anti-receptor-binding domain antibody antibody levels Antibody Response asked blood draw BNT162b2 booster booster dose booster doses chronic disease circulating variants Complete CoronaVac coronavirus dose evaluated Follow-up groups healthcare worker Healthcare workers Heterologous heterologous vaccination homologous or heterologous humoral Humoral response IgG Immunoglobulin Immunoglobulin G Inactivated vaccine independent predictor independent predictors levels of antibody Limited Messenger RNA Odds ratio participant Participants prospective cohort study Quantitative questionnaire RBD reduction respiratory risk SARS-CoV-2 second dose Seropositivity severe acute respiratory syndrome Coronavirus single booster dose the median Turkey university hospital vaccination Vaccine waning immunity were infected were measured
[DOI] 10.1002/jmv.27620 PMC 바로가기 [Article Type] Article