Immunogenicity of heterologous inactivated and adenoviral-vectored COVID-19 vaccine: Real-world data이종 불활성화 및 아데노바이러스 매개 COVID-19 백신의 면역원성: 실제 데이터Article Published on 2022-05-202022-09-11 Journal: Vaccine [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] adenoviral-vectored vaccine adenoviral-vectored vaccines Anti-RBD IgG AZD1222 B.1.1.7 B.1.351 B.1.617.2 CMIA CoronaVac country COVID-19 COVID-19 vaccine elicited ELISA enrolled enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay followed by group Heterologous heterologous vaccine homologous IgG immunoassay immunogenicity inactivated Limited Microparticle neutralization test Neutralizing activity neutralizing antibody participant recipient recipients regimen response SARS-CoV-2 SARS-CoV-2 variants sera serum sample serum samples subset surrogate virus neutralization test sVNT tested the SARS-CoV-2 Vaccine variant variants variants of concern virus neutralization test was tested Wuhan Wuhan strain [DOI] 10.1016/j.vaccine.2022.04.043 PMC 바로가기 [Article Type] Article
Persistence of Anti SARS-CoV-2 Antibodies in Breast Milk from Infected and Vaccinated Women after In Vitro-Simulated Gastrointestinal Digestion체외 모의 위장 소화 후 감염 및 백신 접종 여성의 모유 내 항 SARS-CoV-2 항체 지속성Article Published on 2022-05-192022-09-12 Journal: Nutrients [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] anti-SARS-CoV-2 antibodies antibody approach BNT162b2 mRNA Breast breast milk Breastfeeding colonic colonic fermentation Compound control group COVID-19 cut-off value demonstrated digested digestion ELISA expected fecal Gastrointestinal gastrointestinal tract group growth Gut gut microbiota IgA IgG IgG antibody immunization in vitro in vitro digestion Infant Infection intestinal lactating women lactation lactation. microbial microbiota milk mRNA vaccination mRNA-1273 no effect pathway persistence positive qPCR receiving recent reduced remained SARS-CoV-2 SARS-CoV-2 antibody significantly Specific stages tested the antibody the study group vaccination virus was determined was tested women [DOI] 10.3390/nu14102117 PMC 바로가기 [Article Type] Article
Structure-guided affinity maturation of a novel human antibody targeting the SARS-CoV-2 nucleocapsid proteinSARS-CoV-2 뉴클레오캡시드 단백질을 표적으로 하는 새로운 인간 항체의 구조 유도 친화성 성숙Article Published on 2022-05-192022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료법, [키워드] Affinity maturation antibody binding biological function BLI candidate complex conserved Diagnosis diagnostic effective Evidence expected genome sequence global pandemic higher affinity homology Interaction linker magnitude marker molecular docking mutant Mutation N protein nucleocapsid protein pandemic peptide predicted Prevention and control Protein recent recognize residue SARS-CoV-2 SARS-CoV-2 N protein SARS-CoV-2 nucleocapsid SARS-CoV-2 pandemic scFv shown Structure the N protein the SARS-CoV-2 therapeutic drug Treatment was tested [DOI] 10.1038/s41598-022-12242-0 PMC 바로가기 [Article Type] Article
Safety and Immunogenicity of Inactivated and Recombinant Protein SARS-CoV-2 Vaccines in Patients With Thyroid Cancer갑상선암 환자에서 비활성화 및 재조합 단백질 SARS-CoV-2 백신의 안전성 및 면역원성Observational Study Published on 2022-05-132022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] acute respiratory syndrome Adults All participant BBIBP-CorV booster vaccination Cancer cancer patient Cancer patients Chongqing Complication CoronaVac coronavirus Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) dose Fever FIVE healthy humoral immunogenicity inactivated Inactivated SARS-CoV-2 vaccine injection site pain participant Patient ranged recombinant Safe Safety SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 IgG antibody SARS-CoV-2 vaccination SARS-CoV-2 vaccine second severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Side effect significantly significantly shorter the SARS-CoV-2 Thyroid university vaccination Vaccine was tested were recorded ZF2001 [DOI] 10.3389/fimmu.2022.855311 PMC 바로가기 [Article Type] Observational Study
Preclinical Assessment of IgY Antibodies Against Recombinant SARS-CoV-2 RBD Protein for Prophylaxis and Post-Infection Treatment of COVID-19COVID-19의 예방 및 감염 후 치료를 위한 재조합 SARS-CoV-2 RBD 단백질에 대한 IgY 항체의 전임상 평가Article Published on 2022-05-102022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] administration Against antibody approach assessment COVID-19 COVID-19 infection COVID-19 pandemic death demonstrated develop Efficacy egg-yolk antibodies hamster histopathological IgY immunoreactivity infected patients intranasally Mortality neutralization outbreak pandemic passive immunity passive immunization performed Post-infection Preclinical produced prophylactic treatment protective effect purified Receptor binding domain recombinant recombinant RBD protein Safety SARS-CoV-2 SARS-CoV-2 RBD therapy Treatment Vaccine was tested [DOI] 10.3389/fimmu.2022.881604 PMC 바로가기 [Article Type] Article
The clinical features and estimated incidence of MIS-C in Cape Town, South Africa남아프리카 케이프타운에서 MIS-C의 임상적 특징 및 추정 발생률Article Published on 2022-05-022022-09-12 Journal: BMC Pediatrics [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] abdominal pain Affect age Analysis black calculated Cape cardiac children children with MIS-C clinical clinical feature clinical manifestation Coagulation Cohort collected comparison CRP D-dimer deaths demographic data Diagnosis eight Epidemiology ferritin Fever fibrinogen global health Haemoglobin healthy children highlight hospital Hospital stay ICU admission immune incidence independent Infection Inflammatory intravenous invasive ventilation involved lack Logistic regression Low-middle income countries marker median median age Methylprednisolone MIS-C neutrophil count organ system outcome Oxygen therapy paediatrics pandemic performed Peritoneal dialysis Rash recruited renal required SARS-CoV-2 SARS-CoV-2 antibodies serum Seven sodium South Africa Support Surveillance syndrome Tachycardia the healthy town Treatment was tested white cell [DOI] 10.1186/s12887-022-03308-z PMC 바로가기 [Article Type] Article
Comparison of COVID-19 laboratory diagnosis by commercial kits: Effectivity of RT-PCR to the RT-LAMP상용 키트에 의한 COVID-19 실험실 진단의 비교: RT-LAMP에 대한 RT-PCR의 유효성Article Published on 2022-05-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] 2019-nCoV acute respiratory syndrome acute respiratory syndrome coronavirus approach caused Chain Reaction contribute coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Diagnosis diagnostic diagnostic test diagnostic testing Effect Effectiveness effort evaluate faster gold gold standard IMPROVE individual isothermal amplification Laboratory LAMP LAMP-PCR Loop-mediated isothermal amplification MONITOR Nasopharyngeal swab nasopharyngeal swabs Novel coronavirus pandemic Patient PCR polymerase chain reaction portion q-RT-PCR q-RT-PCR. Qiagen quantification quantitative reverse transcription-polymerase chain reaction Randomly Rotor-Gene Q RT-LAMP RT-PCR RT-PCR kit SARS-CoV-2 SARS-CoV-2 test sequence severe acute respiratory syndrome Coronavirus technology tested the SARS-CoV-2 Transcription was tested [DOI] 10.1002/jmv.27559 PMC 바로가기 [Article Type] Article
The Prevalence of Mycoplasma Pneumoniae Among Children in Beijing Before and During the COVID-19 PandemicCOVID-19 팬데믹 이전과 동안 베이징 어린이의 마이코플라스마 폐렴 유병률Article Published on 2022-04-292022-09-12 Journal: Frontiers in Cellular and Infection Microbiology [Category] 진단, [키워드] age analyzed antibody Beijing Capital children China Clinical data collected Community coronavirus disease COVID-19 COVID-19 pandemic demonstrated dropped effectively controlled Epidemic feature Gender groups highest immunochromatographic assay investigated lowest measure Measures Mycoplasma Mycoplasma pneumoniae no significant difference outbreak pathogen Patient pediatrics Pneumonia pneumoniae positive positive rate Prevalence Respiratory disease respiratory infection restrictive measures. RStudio software serum significant difference significantly higher specimen statistically significant Transmission was tested [DOI] 10.3389/fcimb.2022.854505 PMC 바로가기 [Article Type] Article
Fluorescent bioassay for SARS-CoV-2 detection using polypyrene-g-poly(ε-caprolactone) prepared by simultaneous photoinduced step-growth and ring-opening polymerizations동시 광유도 단계 성장 및 개환 중합에 의해 제조된 폴리피렌-g-폴리(ε-카프로락톤)를 사용한 SARS-CoV-2 검출을 위한 형광 생물검정Article Published on 2022-04-262022-09-11 Journal: Mikrochimica Acta [Category] COVID19(2023년), SARS, 치료기술, [키워드] Analysis approach calibrated characterized coefficient Coefficient of variation construction demonstrated described Diagnosis feature Fluorescence fluorescence intensity fluorescent Fluorescent biosensor Graft Graft copolymer high correlation immunofluorescence limit of detection Nasopharyngeal samples negative and positive Photopolymerization platform pyrene quantification repeatability reporter reproducibility Ring-opening polymerization RT-PCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2-specific antibodies SARS-CoV-2-specific antibody Significant significant differences spectral analysis Step-growth polymerization. Variation was tested was used [DOI] 10.1007/s00604-022-05244-2 PMC 바로가기 [Article Type] Article
ACE2-based capacitance sensor for rapid native SARS-CoV-2 detection in biological fluids and its correlation with real-time PCR생물학적 유체에서 신속한 기본 SARS-CoV-2 감지 및 Real-Time PCR과의 상관 관계를 위한 ACE2 기반 정전 용량 센서Article Published on 2022-04-152022-09-11 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] ACE2 protein addition antibody Antibody free biological fluid biosensor can be used condition correlated correlation demonstrated detection Diagnostic method diagnostic methods effective electrical examined experiment gold Health hospitalized patient hospitalized patients immobilization Interdigitated electrodes Laboratory less limit of detection MONITOR Particular point of care positive Real-time PCR replicate reproducibility Saliva saliva samples SARS-CoV-2 SARS-CoV-2 biosensor. SARS-CoV-2 detection semi-quantitative sensor Spike protein Spread stability Swab the SARS-CoV-2 virus was tested was used weakly positive [DOI] 10.1016/j.bios.2022.114021 PMC 바로가기 [Article Type] Article