Impact of Prediabetes and Type-2 Diabetes on Outcomes in Patients with COVID-19Research Article Published on 2021-06-162022-10-30 Journal: International Journal of Endocrinology [Category] COVID-19, [키워드] age binomial control group demonstrated determine diabete diagnosed Evidence group had no hospitalized patient hyperglycemia Impact Infection less lower mortality mechanical ventilation Mortality not affect older patient outcome outcomes Patient patients with COVID-19 Prediabete predictor Presence regression analysis Result retrospective SARS-COV-2 infection significantly higher single-center survival three group type-2 diabete type-2 diabetes was used with COVID-19 younger patient [DOI] 10.1155/2021/5516192 PMC 바로가기 [Article Type] Research Article
Evidence for Biological Age Acceleration and Telomere Shortening in COVID-19 SurvivorsCOVID-19 생존자의 생물학적 연령 가속 및 텔로미어 단축에 대한 증거Hypothesis Published on 2021-06-072022-09-10 Journal: International Journal of Molecular Sciences [Category] MERS, 바이오마커, 유전자 메커니즘, [키워드] acceleration ACE2 ACE2 expression age age determination alteration analyzed Biological biological age characterized Cohort COVID-19 CpG cytokine death defined DeltaAge determine difficulty DIFFICULTY CONCENTRATING DNA methylation DPP-4 Dyspnea Epigenetic epigenetics fatigue fibrosis Immunosuppression increase in Inflammatory cytokine memory memory loss non-infected normality post-COVID-19 Post-COVID-19 patients PPCs pyrosequencing respiratory distress SARS-COV-2 infection Severe respiratory distress shortening sleep disorders subject survivor Survivors syndrome telomere telomeres Volunteer world population younger patient younger patients [DOI] 10.3390/ijms22116151 PMC 바로가기 [Article Type] Hypothesis
Pathophysiologic mechanisms of cerebral endotheliopathy and stroke due to Sars-CoV-2Sars-CoV-2로 인한 뇌내피병증 및 뇌졸중의 병태생리학적 기전Review Published on 2021-06-012022-09-12 Journal: Journal of cerebral blood flow and metabolism : of [Category] MERS, 진단, [키워드] activate Activation Atypical cascade cerebrovascular complement condition connection contribute cytokine driving endothelia Endothelial cell endotheliopathy event global pandemic Hemorrhagic hypercoagulability identify implicated increase in independent Infection Inflammation Injury Ischemia mechanism modulate molecular overlap pathogenesis of stroke pathogenic mechanism pathophysiology pathway provide reducing resulting SARS-CoV-2 signaling pathways stroke suggested syndrome synergism triggered underlie variety vasculature younger patient [DOI] 10.1177/0271678X20985666 PMC 바로가기 [Article Type] Review
A systematic review on the recurrence of SARS-CoV-2 virus: frequency, risk factors, and possible explanationsSARS-CoV-2 바이러스의 재발에 대한 체계적인 검토: 빈도, 위험 요인 및 가능한 설명Article Published on 2021-05-012022-09-12 Journal: Infectious diseases (London, England) [Category] 진단, [키워드] affected articles caused Cohort studies coronavirus coronavirus disease Course COVID-19 database deaths disease Evidence Frequency IgG and IgM include inclusion criteria notable Patient PCR performed positive ranged recovered patients recurrence Reinfection remained reported required risk Risk factors SARS-CoV-2 SARS-CoV-2 genome severity systematic review the disease virus younger patient [DOI] 10.1080/23744235.2020.1871066 PMC 바로가기 [Article Type] Article
The clinical spectrum of COVID-19-associated cutaneous manifestations: An Italian multicenter study of 200 adult patientsCOVID-19 관련 피부 증상의 임상 스펙트럼: 200명의 성인 환자를 대상으로 한 이탈리아 다기관 연구Multicenter Study Published on 2021-05-012022-09-12 Journal: Journal of the American Academy of Dermatology [Category] SARS, 진단, [키워드] age asked Asymptomatic Clinical characteristics coronavirus COVID-19 COVID-19 severity cutaneous manifestation Infection Italian lesion lesions less manifestation Manifestations Mild moderate multicenter Patient phenotype SARS-CoV-2 severe COVID-19 severity of COVID-19 significantly skin manifestations the median the patient unit younger patient [DOI] 10.1016/j.jaad.2021.01.023 PMC 바로가기 [Article Type] Multicenter Study
Utility of hospitalization for elderly individuals affected by COVID-19Research Article Published on 2021-04-262022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] affected age Care COVID-19 COVID-19 pandemic COVID-19 patient decrease detrimental effect Elderly patient examined exceeded greater Health hospital Hospital admission Hospitalization Hospitalized hospitals individual individuals Italy management median age Mortality mortality data mortality rate not affect Older organizations resource Result retrieved SMR the median the patient utility younger patient younger patients [DOI] 10.1371/journal.pone.0250730 PMC 바로가기 [Article Type] Research Article
Acute Ischemic Stroke During the Convalescent Phase of Asymptomatic COVID-2019 Infection in Men남성의 무증상 COVID-2019 감염의 회복기 동안의 급성 허혈성 뇌졸중Research Published on 2021-04-222022-09-25 Journal: JAMA Network Open [Category] MERS, SARS, 임상, 진단, [키워드] 95% CI absence age AIS antibodies Asymptomatic COVID-19 Care case sery clinical Cohort complications of COVID-19 convalescent convalescent phase convalescent stage country Course COVID-19 COVID-19 case COVID-19 infection COVID-2019 described Diagnosis diagnosis of COVID-19 electronic medical record elevated feature finding hospital Importance incidence rate increased risk India individual Infection intravenous Ischemic Laboratory laboratory-confirmed large vessel male measure median Nasopharyngeal swab National neurological objective participant Patient patients phase Point positive public health Relevance respiratory symptom respiratory symptoms Result retrieved risk Risk factors SARS-CoV-2 scale serological serological test Serological testing setting sex- Singapore South Asian stroke the median therapy were excluded younger patient [DOI] 10.1001/jamanetworkopen.2021.7498 PMC 바로가기 [Article Type] Research
Rural Telemedicine Use Before and During the COVID-19 Pandemic: Repeated Cross-sectional StudyOriginal Paper Published on 2021-04-052022-10-30 Journal: Journal of Medical Internet Research [Category] Coronavirus, MERS, SARS, [키워드] age all age groups Canada Care changes in Characteristics chronic disease Chronic illness conducted COVID-19 COVID-19 pandemic cross-sectional evaluate female Future group Health Health care Health services highest identify increase in less male notable objective Older Older adults older patient outcomes pandemic Patient patients Population population level populations potential barrier proportion Region remote repeated reported Result rural significantly higher significantly increased Telemedicine telemedicine visit Virtual care younger patient [DOI] 10.2196/26960 PMC 바로가기 [Article Type] Original Paper
The effect of age on the clinical and immune characteristics of critically ill patients with COVID-19: A preliminary reportResearch Article Published on 2021-03-182022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] 2019-nCoV infection Admission age ARDS Bilirubin blood pressure BNP C-reactive protein CD4+ CD8+ T lymphocytes China chronic clinical close monitoring collected Comorbidities Confusion coronavirus disease COVID-19 COVID-19 patients critical condition Critically ill Critically ill patient CRP CURB-65 D-dimer develop disease Disease progression dynamic elderly patients exhibited Fever groups Health authority hospital IL-10 immune characteristics information laboratory parameter lactate dehydrogenase LDH less Local lymphocyte Lymphocyte count mechanical ventilation National Health Commission NKT occurred Older older patient older patients PaO2 Patient patients patients with COVID-19 PCT peptide performed pH value Physiology Platelet preliminary report procalcitonin proportion receive Result Septic shock Seven significant difference significantly higher significantly increased Symptom T lymphocyte T lymphocytes trajectory Treatment university urea with COVID-19 younger patient younger patients [DOI] 10.1371/journal.pone.0248675 PMC 바로가기 [Article Type] Research Article
Modeling SARS-CoV-2 viral kinetics and association with mortality in hospitalized patients from the French COVID cohort프랑스 COVID 코호트의 입원 환자에서 SARS-CoV-2 바이러스 역학 및 사망률과의 연관성 모델링422 Published on 2021-02-232022-09-12 Journal: Proceedings of the National Academy of Sciences of [Category] MERS, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age Analysis analyzed association average build characterization chronic pulmonary disease Cohort collected coronavirus COVID death disease Effect effective Evolution French Gender hazard ratio High-risk patients Hospital admission hospitalized patient hospitalized patients identify independent infected cells information joint male mathematical mathematical model median median time modeling Mortality mortality rate Multivariate analysis nasopharyngeal viral occur older patients outcome Patient pharmacological intervention predict predicted prolonged viral shedding pulmonary disease reduce reduction respiratory risk factor Risk factors risk of death SARS-CoV-2 SARS-CoV-2 viral kinetics severe acute respiratory syndrome Coronavirus Significance Strategy survival symptom onset translate Treatment Treatment strategies Viral viral clearance viral dynamics viral kinetics Viral load Virological virus virus pathogenesis younger patient younger patients [DOI] 10.1073/pnas.2017962118 PMC 바로가기 [Article Type] 422