USA stockpiling of remdesivir: How should the world respond?미국의 렘데시비르 비축: 세계는 어떻게 대응해야 할까요?Review Published on 2020-12-042022-09-10 Journal: Journal of Comparative Effectiveness Research [Category] SARS, 치료제, [키워드] Antiviral coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Dexamethasone effective Emergency use Evidence low-dose patients hospitalized Remdesivir respiratory respiratory symptoms SARS-CoV-2 severe respiratory symptoms stockpiling Treatment USA widespread [DOI] 10.2217/cer-2020-0174 PMC 바로가기 [Article Type] Review
Incidence of Suspected Serious Adverse Drug Reactions in Corona Virus Disease-19 Patients Detected by a Pharmacovigilance Program by Laboratory Signals in a Tertiary Hospital in Spain: Cautionary DataPharmacology Published on 2020-12-032022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] 95% CI Acute kidney injury Adverse adverse (side) effects Adverse drug reaction ALS analyzed Anemia caution cerebrospinal fluid chloroquine/hydroxychloroquine Corona corona virus disease-19 (COVID-19) COVID-19 patient COVID-19 patients Dexamethasone distribution drug eosinophilia Hepatitis hepatotoxic hospital hospitalized patient hyponatremia incidence incidence rate induce Laboratory leukocyte Lopinavir-ritonavir medication neutropenia non-COVID-19 patient Non-COVID-19 patients pandemic patients patients with COVID-19 pharmacovigilance pharmacovigilance process Program reaction reflected serious adverse drug reaction signal Spain Suspected Tertiary the SARS-CoV-2 Thromboembolic events Tocilizumab [DOI] 10.3389/fphar.2020.602841 PMC 바로가기 [Article Type] Pharmacology
Profile and outcomes of hospitalized patients with COVID-19 at a tertiary institution hospital in GhanaOriginal Article Published on 2020-12-012022-10-31 Journal: Ghana Medical Journal [Category] COVID-19, MERS, SARS, [키워드] age analysed breathlessness clinical co-morbidity Comorbidity Coronavirus disease 2019 COVID-19 COVID-19 admission Critical determinant Dexamethasone died fatality Fever funding Ghana hospital Hospitalized hospitalized COVID-19 patient hospitalized patient Hydroxychloroquine IMPROVE Increasing KNUST Kwame Nkrumah males management Mild moderate Mortality multivariate logistic regression objective outcome outcomes Patient patients polymerase chain predictor profile Prospective Study real time Result Science severity standardized protocol Stratification sub-Saharan Africa Symptom Systolic blood pressure technology the patient Treatment university with COVID-19 [DOI] 10.4314/gmj.v54i4s.7 PMC 바로가기 [Article Type] Original Article
COVID-19, myocardial edema and dexamethasoneCOVID-19, 심근 부종 및 덱사메타손Article Published on 2020-12-012022-09-11 Journal: Medical Hypotheses [Category] 치료제, [키워드] acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome Antiviral antiviral agent ARDS cause of death Corona virus coronavirus coronavirus disease COVID-19 cytokine Cytokine storm syndrome death develop Dexamethasone Dyspnea edema effective endothelial FDA gcs glucocorticoid Glucocorticoids high mortality rate Hospitalized hospitalized COVID-19 patients Hypoxemia kidney lead Liver injury Myocardial Myocardium Numerous Patient patient with COVID-19 poor prognosis progression randomized trial reducing mortality respiratory respiratory distress Respiratory failure Safe Severe acute respiratory syndrome Severe Acute Respiratory Syndrome Corona Virus severe COVID-19 stability syndrome therapeutic effect therapeutic effects tissue Treatment Vascular vascular permeability virus [DOI] 10.1016/j.mehy.2020.110307 PMC 바로가기 [Article Type] Article
COVID-19, steroids and other immunomodulators: The jigsaw is not completeCOVID-19, 스테로이드 및 기타 면역 조절제: 퍼즐은 완전하지 않습니다Editorial Published on 2020-12-012022-09-11 Journal: Anaesthesia, critical care & pain medicine [Category] SARS, 임상, 진단, [키워드] Abstract ARDS Complete COVID-19 Dexamethasone IL6-R blockade Pneumonia SARS steroid Tocilizumab [DOI] 10.1016/j.accpm.2020.10.011 PMC 바로가기 [Article Type] Editorial
Immune Therapy, or Antiviral Therapy, or Both for COVID-19: A Systematic ReviewCOVID-19에 대한 면역 요법, 항바이러스 요법 또는 둘 다: 체계적인 검토Article Published on 2020-12-012022-09-11 Journal: Drugs [Category] MERS, SARS, 진단, 치료제, [키워드] Admission Anakinra analysed Antiviral antivirals article articles Baricitinib case reports Characteristics Chloroquine Clinical features clinical impact Colchicine combination therapy control group COVID-19 COVID-19 patient cumulative Cytokine release syndrome database deaths Dexamethasone discharge disease dysregulation Efficacy eligibility criteria English language Evidence exclusion explain Favipiravir first stage Google Scholar helping High-flow oxygen Hydroxychloroquine identify immune immune dysregulation immune response Inclusion Inconclusive indicated Infection intensive care intensive care unit intensive care unit admission item itolizumab large trial Loading dose Lopinavir Lopinavir/ritonavir management medRxiv meta-analyses Mortality Open-label oxygen Pathogenesis pathogenesis of COVID-19 pathogenic mechanism patients primary end point PRISMA Randomised controlled trials rationale RCTs reduced reduction Remdesivir removal reported Reporting requiring high-flow oxygen retrospective review Ritonavir ruxolitinib sarilumab SARS-CoV-2 SARS-COV-2 infection significantly siltuximab supportive therapy systematic review systematic reviews the disease the SARS-CoV-2 therapeutic therapeutic agent Therapeutic approach therapeutic approaches therapy Time to recovery Tocilizumab Treatment treatment of COVID-19 patients Trial trials triggered USA was performed were excluded [DOI] 10.1007/s40265-020-01421-w PMC 바로가기 [Article Type] Article
COVID-19 and Acute SarcopeniaCommentary Article Published on 2020-12-012022-10-28 Journal: Aging and Disease [Category] COVID-19, [키워드] Acute benefits of treatment Clinical practice clinician consequence COVID-19 COVID-19 pandemic Decline defined Dexamethasone increasingly mechanism Muscle strength occur Older Patient physical recommendation Research risk risk of death sarcopenia suffered survivor the disease Treatment [DOI] 10.14336/AD.2020.1014 PMC 바로가기 [Article Type] Commentary Article
Treatment Experience With Inhaled Corticosteroids in Combination with Remdesivir and Dexamethasone Among COVID-19 Patients Admitted to a Rural Community Hospital: A Case SeriesFamily/General Practice Published on 2020-11-302022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory distress acute respiratory syndrome ARDS benefit case sery caused Combination coronavirus coronavirus disease COVID 19 COVID-19 COVID-19 patient current Dexamethasone dexamethasone convalescent plasma discharged home evaluated experience expired highlight hypoxia hypoxic ICS Infectious disease information Inhaled inhaled corticosteroid inhaled steroids lung medications one patient outcome outcomes pandemic era Patient randomized controlled study Remdesivir resulting retrospective SARS-CoV-2 Sery severe inflammation steroid Support syndrome Systemic steroid treated treating COVID-19 patients Treatment treatment guideline [DOI] 10.7759/cureus.11787 PMC 바로가기 [Article Type] Family/General Practice
Corticosteroid use in viral pneumonia: experience so far and the dexamethasone breakthrough in coronavirus disease-2019Review Published on 2020-11-272022-10-29 Journal: Journal of Comparative Effectiveness Research [Category] COVID-19, MERS, SARS, [키워드] acute respiratory distress acute respiratory distress syndrome ARDS benefit coronavirus Coronavirus infection Corticosteroid Corticosteroids COVID-19 decrease Dexamethasone effective etiology Evidence Hospital stay in viral Inconclusive Middle East Mortality mortality rate observational study Pneumonia randomized control study retrospective severe COVID-19 shown syndrome therapy use of corticosteroid [DOI] 10.2217/cer-2020-0146 PMC 바로가기 [Article Type] Review
A brief review of the neurological manifestations of the coronavirus diseaseReview Published on 2020-11-232022-10-31 Journal: The Egyptian Journal of Neurology, Psychiatry and Neurosurgery [Category] COVID-19, [키워드] abnormality Antiviral agents Autopsy Blood Cell Central nervous system cerebral cerebrospinal fluid Cerebrovascular disease Clinical studies Coagulation system Combination coronavirus coronavirus disease Coronavirus infection COVID-19 demonstrated Dexamethasone edema Encephalitis Encephalomyelitis Encephalopathy Evidence Google Scholar high mortality Immunoglobulin immunopathology infected patients Infection manifestation Miller fisher syndrome nervous system Neurological disease neurological manifestation neuronal occur olfactory Patient polymerase chain Remdesivir risk severity shown strain stroke Treatment viral damage viral encephalitis virus was done [DOI] 10.1186/s41983-020-00244-6 PMC 바로가기 [Article Type] Review