sera – Page 50 – Communicable Diseases Research

High-Throughput Multiplex SARS-CoV-2 IgG Microsphere Immunoassay for Dried Blood Spots: A Public Health Strategy for Enhanced Serosurvey Capacity

건혈 반점에 대한 고처리량 멀티플렉스 SARS-CoV-2 IgG 미소구체 면역분석: 혈청 조사 능력 향상을 위한 공중 보건 전략

Research Article

Published on 2021-07-282022-09-10
Journal: Microbiology Spectrum [Category] SARS, 변종, 진단, 치료기술, 치료법,

The C-Terminal Half of SARS-CoV-2 Nucleocapsid Protein, Industrially Produced in Plants, Is Valid as Antigen in COVID-19 Serological Tests

Plant Science

Published on 2021-07-272022-10-31
Journal: Frontiers in Plant Science [Category] COVID-19,

[키워드] Affect antibody Antigen biofactories calculated city coronavirus disease Council COVID-19 COVID-19 diagnosis develop Diagnosis diagnostic diagnostic test diagnostic tests ELISA ELISA coronavirus enzyme-linked immunosorbent expressed expression human sera individual Laboratory molecular farming N antigen N protein Nicotiana benthamiana pandemic plant plant expression plants platform positive result producing protein antigen purification reagent Recombinant protein Research Result RT-PCR SARS CoV-2 nucleocapsid protein SARS-CoV-2 SARS-CoV-2 antibody sensitivity Sensitivity and specificity sera serological shown specificity subset Support Test tested the N protein turnaround times was used were used
[DOI] 10.3389/fpls.2021.699665 PMC 바로가기 [Article Type] Plant Science

Assessment of infectivity and the impact on neutralizing activity of immune sera of the COVID-19 variant, CAL.20C

COVID-19 변종 CAL.20C의 면역 혈청의 감염력 및 중화 활성에 대한 영향 평가

Comment

Published on 2021-07-272022-09-10
Journal: Signal Transduction and Targeted Therapy [Category] Fulltext, SARS, 변종, 진단,

[키워드] assessment CAL.20C COVID-19 immune Infectious diseases Neutralizing activity sera variant
[DOI] 10.1038/s41392-021-00695-0 PMC 바로가기 [Article Type] Comment

B.1.526 SARS-CoV-2 Variants Identified in New York City are Neutralized by Vaccine-Elicited and Therapeutic Monoclonal Antibodies

B.1.526 뉴욕시에서 확인된 SARS-CoV-2 변이체가 백신 유도 및 치료용 단일클론 항체에 의해 중화됨

Observation

Published on 2021-07-272022-09-10
Journal: mBio [Category] MERS, SARS, 변종, 진단,

Impact of the Second Epidemic Wave of SARS-CoV-2: Increased Exposure of Young People

SARS-CoV-2의 두 번째 전염병 영향: 젊은이들의 노출 증가

Public Health

Published on 2021-07-262022-09-11
Journal: Frontiers in Public Health [Category] MERS, SARS, 진단, 치료기술,

[키워드] age age and sex anti-SARS-CoV-2 IgG antibodies antibody Antibody titer borderline clinical laboratories Clinical management collected Corsica cross-sectional ELISA enzyme-linked immunosorbent assay Estimated estimates exposure First wave France Frequency herd immunity house IgG antibodies IgG antibody Impact Increased individual Laboratory men neutralization neutralization test Neutralizing antibodies Odds ratio P -value participant Patient positive produced profile proportion residual S1 domain Sample SARS-CoV-2 second second wave semi-quantitative sera serological surveillance seroneutralization Seroprevalence significantly significantly higher Spike protein tested Viral viral spike protein virus neutralization test VNT Wave women
[DOI] 10.3389/fpubh.2021.715192 PMC 바로가기 [Article Type] Public Health

SARS-CoV-2 Infection in Dogs and Cats from Southern Germany and Northern Italy during the First Wave of the COVID-19 Pandemic

Covid-19 Pandemic의 첫 번째 물결 동안 독일 남부 및 이탈리아 북부의 개와 고양이에서 SARS-COV-2 감염

Communication

Published on 2021-07-262022-09-10
Journal: Viruses [Category] SARS, 치료기술, 치료제,

[키워드] (RdRp 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus affected analyzed animal anti-SARS-CoV-2 antibody cats Chain Reaction clinics coronavirus coronavirus disease COVID-19 dog domestic animals First wave Genes Germany highlighting hotspot humans Hypothesis incidence Italian Italy Laboratory lombardy nasal swab Neutralizing activity one health Oropharyngeal oropharyngeal swab pandemic patients Piedmont polymerase chain polymerase chain reaction populations positive Prevalence qPCR RBD RdRP Receptor binding domain recruited Region respiratory Respiratory disease reverse transcriptase risk RNA RNA polymerase RT-qPCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA sera Serologically serology severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 shown specimen Support Surveillance susceptible tested transcriptase Viral viral envelope Wave zoonosis zoonotic transmission
[DOI] 10.3390/v13081453 PMC 바로가기 [Article Type] Communication

Neutralizing activity of Sputnik V vaccine sera against SARS-CoV-2 variants

Article

Published on 2021-07-262022-10-04
Journal: Nature Communications [Category] SARS, 변종, 유전자 메커니즘,

Elicitation of Broadly Neutralizing Antibodies against B.1.1.7, B.1.351, and B.1.617.1 SARS-CoV-2 Variants by Three Prototype Strain-Derived Recombinant Protein Vaccines

3 개의 프로토 타입 변형 유래 재조합 단백질 백신에 의한 B.1.1.7, B.1.351 및 B.1.617.1 SARS-COV-2 변이체에 대한 광범위하게 중화 항체의 유도

Communication

Published on 2021-07-222022-09-01
Journal: Viruses [Category] SARS, 변종, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antigen approved B.1.1.7 B.1.351 B.1.617.1 caused circulating SARS-CoV-2 variants comparable coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 domain dose ectodomain effective evaluated exhibited GMTs immune Immune escape information less long-lasting mice MOST neutralization potency Neutralizing Neutralizing antibodies neutralizing antibody Neutralizing titer pandemic performed Protein prototype raised RBD Receptor binding domain Receptor-binding domain recombinant Recombinant protein remained respiratory S1 SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 vaccines SARS-CoV-2 variant SARS-CoV-2 variants sera severe acute respiratory syndrome Coronavirus Spike protein Support tested the RBD the vaccine trimer type strain Vaccine vaccine antigen variant Variation virus viruses wild-type strain
[DOI] 10.3390/v13081421 PMC 바로가기 [Article Type] Communication

Highly feasible immunoprotective multicistronic SARS-CoV-2 vaccine candidate blending novel eukaryotic expression and Salmonella bactofection

새로운 진핵생물 발현과 살모넬라 박토펙션을 혼합한 매우 실현 가능한 면역보호 멀티시스트론 SARS-CoV-2 백신 후보

Article

Published on 2021-07-222022-09-11
Journal: Journal of advanced research [Category] COVID19(2023년), MERS, SARS, 변종, 유전자 메커니즘, 진단,

[키워드] Analysis anti-SARS-CoV-2 immune responses Antibody titers antigen-specific antibody Antiviral CD4 CD8 Cell-mediated immunity Cellular immune response co-expression COVID-19 Cytometry demonstrated determine develop DNA domain effective Efficacy Efficiency elicited epitope Epitopes eukaryotic expressing expression feasible Flow flow cytometry Frame fused gene delivery heptad repeat highest humoral immune responses immunized mice immunofluorescence assay immunogenicity IMPROVE in vivo increase in investigated mechanism membrane protein mice mRNA Multicistronic expression multivalent vaccine neutralizing antibody titers nsp13 offer Open reading frame pandemic peptide polarization Protein protein expression raised RBD recall Receptor-binding domain recorded RNA robust Safe Salmonella SARS-CoV-2 SARS-CoV-2 gene SARS-CoV-2 genes SARS-CoV-2 neutralizing antibody SARS-CoV-2 protein SARS-CoV-2 proteins SARS-CoV-2 vaccine SARS-CoV-2 variant SARS-CoV-2 variants sera Spike protein splenocyte splenocytes suggested T cell T cells targets Th1 Th1 response Th2 immunity the spike protein the vaccine Vaccine vaccine candidate vaccine construct variant variants were used western blot Western blot analysis
[DOI] 10.1016/j.jare.2021.07.007 PMC 바로가기 [Article Type] Article

Development of rapid and cost-effective top-loading device for the detection of anti-SARS-CoV-2 IgG/IgM antibodies

항 -SARS-COV-2 IgG/IgM 항체의 검출을위한 신속하고 비용 효율적인 상단 로딩 장치의 개발

Article

Published on 2021-07-212022-09-01
Journal: Scientific Reports [Category] SARS, 변종, 진단, 치료기술,