Implementation and Accuracy of BinaxNOW Rapid Antigen COVID-19 Test in Asymptomatic and Symptomatic Populations in a High-Volume Self-Referred Testing Site대규모 자가 추천 검사장에서 무증상 및 무증상 집단을 대상으로 한 BinaxNOW Rapid Antigen COVID-19 검사의 구현 및 정확성Research Article Published on 2021-12-012022-09-12 Journal: Microbiology Spectrum [Category] SARS, 진단, [키워드] 95% CI 95% confidence interval Abbott Abbott Laboratories Antigen Asymptomatic asymptomatic individual Asymptomatic individuals close contact Community COVID COVID-19 COVID-19 test Emergency use authorization FDA field hospital greater groups Health care Health care worker health care workers high accuracy identify implementation individuals Isolation Laboratory monoclonal antibody monoclonal antibody treatment MOST participant PCR test PCR testing performed point-of-care testing Population positive Rapid rapid antigen testing Rapid antigen tests reported reverse transcription PCR SARS-CoV-2 sensitivity Sensitivity and specificity Site Symptom symptom status symptomatic symptomatic individual symptomatic individuals Test Testing threshold Treatment [DOI] 10.1128/Spectrum.01008-21 PMC 바로가기 [Article Type] Research Article
Medically Ill hospitalized Patients for COVID-19 THrombosis Extended ProphyLaxis with rivaroxaban ThErapy: Rationale and Design of the MICHELLE TrialRandomized Controlled Trial Published on 2021-12-012022-10-05 Journal: American heart journal [Category] 임상, [키워드] abnormality Clinical practice Coagulation Combination Computed tomography Consensus COVID-19 COVID-19 patient criteria death discharge disease dosage Efficacy endothelial damage Endpoint evaluate events Evidence expected Extended help hospital discharge Hospitalization Hospitalized Ill In-hospital incidence increased risk Intervention limb lower limb major bleeding mechanisms Myocardial infarction occur outcome pandemic patient with COVID-19 pharmacological Prophylaxis prothrombotic state rationale regimen risk SARS-CoV-2 stroke symptomatic the cytokine storm Thromboembolism Thromboprophylaxis Trial venous VTE [DOI] 10.1016/j.ahj.2021.08.016 PMC 바로가기 [Article Type] Randomized Controlled Trial
Impact of coronavirus disease 2019 (COVID-19) lockdown on in-hospital mortality and surgical activity in elective digestive resections: A nationwide cohort analysisObservational Study Published on 2021-12-012022-10-05 Journal: Surgery [Category] 임상, [키워드] Asymptomatic COVID-19 Cancer Care Cohort cohort analysis control group coronavirus disease COVID-19 COVID-19 infection database defined digestive effort geographical region group hospital Hospital admission Hospital stay Impact in-hospital mortality increased mortality Infection lockdown maintain Mortality National no difference outbreak Patient patients postoperative Primary outcome reduction in remained reported risk factor second wave Support surgical Surgical Procedure surgical resection symptomatic was performed [DOI] 10.1016/j.surg.2020.12.036 PMC 바로가기 [Article Type] Observational Study
Differences in pregnancy and perinatal outcomes among symptomatic versus asymptomatic COVID-19-infected pregnant women: a systematic review and meta-analysisResearch Published on 2021-12-012022-10-28 Journal: BMC Pregnancy and Childbirth [Category] COVID-19, SARS, [키워드] 95% confidence interval Adjusted analysis Admission age analyzed article Asian Asymptomatic black body mass index calculated clinical feature clinical presentation Complication complications conducted coronavirus COVID-19 database difference Evidence greater group hypertensive ICU admission identify infected with SARS-CoV-2 information intensive care unit likelihood management mean difference mechanical ventilation Meta-analysis Neonate no significant difference obese objective Odds ratio outcome Pregnancy pregnant pregnant women Preterm birth PROSPERO reported required respiratory disorder Result review risk factor Risk factors SARS-CoV-2 SARS-COV-2 infection significantly lower suggested supplementary material symptomatic systematic review the mean two groups was performed white women [DOI] 10.1186/s12884-021-04250-1 PMC 바로가기 [Article Type] Research
Correlation of the Commercial Anti-SARS-CoV-2 Receptor Binding Domain Antibody Test with the Chemiluminescent Reduction Neutralizing Test and Possible Detection of Antibodies to Emerging Variants상업용 Anti-SARS-CoV-2 수용체 결합 도메인 항체 테스트와 화학발광 환원 중화 테스트의 상관관계 및 항체의 새로운 변이체 검출 가능Research Article Published on 2021-12-012022-09-10 Journal: Microbiology Spectrum [Category] SARS, 변종, 진단, 치료기술, [키워드] 95% confidence interval Accuracy acquisition acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 anti-RBD anti-receptor-binding domain Antibody test antibody test result antibody tests B.1.1.7 B.1.351 B.1.351 variant B.1.351 variants biohazard clinical laboratory close contact comparable convalescent convalescent COVID-19 patients convalescent phase Coronavirus-2 correlated correlation COVID-19 COVID-19 patient COVID-19 patients Critical defined detection diagnostic disease onset displaying Efficacy episode episode of Evidence evidence of functional healthy individual high throughput identify immune response Immunity indicate Laboratory lead neutralization Neutralizing Neutralizing activity Neutralizing antibodies Neutralizing titer neutralizing titers optimization Patient PCR-negative positive result proof protective immunity provide Pseudotyped virus Pseudotyped viruses Quantitative RBD Receptor-binding domain recognizing reduction respiratory SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants Seroconversion serological test Serological tests serology serum sample serum samples Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus Spike protein Strong symptomatic Test test validity Vaccine vaccine efficacy Validity variant variants virus viruses wild-type [DOI] 10.1128/Spectrum.00560-21 PMC 바로가기 [Article Type] Research Article
Pro-inflammatory CXCL-10, TNF-α, IL-1β, and IL-6: biomarkers of SARS-CoV-2 infection전염증성 CXCL-10, TNF-α, IL-1β 및 IL-6: SARS-CoV-2 감염의 바이오마커Article Published on 2021-12-012022-09-11 Journal: Archives of Virology [Category] 바이오마커, [키워드] antiviral cytokine antiviral cytokines Asymptomatic Biomarker Biomarkers categories category caused chemokine chemokines city clinical manifestation clinical manifestations controls CXCL-10 CXCL10 cytokine cytokine production Cytokines disease early phase except for excessive cytokine production Factor Hospitalized IFN-γ IL-12 IL-17 IL-1β IL-4 IL-6 immune system India individual infected patients Infection infiltration inflammatory cells investigated Level Luminex platform mildly symptomatic patient mildly symptomatic patients morbidity morbidity and mortality no difference Novel coronavirus novel coronavirus SARS-CoV-2 outcome pandemic of COVID-19 Patient Plasma cytokine Postinfection pro-inflammatory cytokine pro-inflammatory cytokines recovered patient recovered patients reduced SARS-COV-2 infection SARS-CoV-2 patient SARS-CoV-2 patients SARS-CoV-2-infected patient significantly higher significantly lower symptomatic the patient TNF-α uninfected control VEGF Viral viral infections virus replication [DOI] 10.1007/s00705-021-05247-z PMC 바로가기 [Article Type] Article
Genomic epidemiology and the role of international and regional travel in the SARS-CoV-2 epidemic in Zimbabwe: a retrospective study of routinely collected surveillance data짐바브웨 SARS-CoV-2 전염병에서 게놈 역학과 국제 및 지역 여행의 역할: 일상적으로 수집되는 감시 데이터에 대한 후향적 연구Article Published on 2021-12-012022-09-11 Journal: The Lancet. Global health [Category] SARS, 변종, 유전자 메커니즘, [키워드] advance Analysis Bayesian methods Biological Biotechnology CDC close contact collected community transmission Council cycle threshold diagnostic effective Epidemic Epidemiology Evolution female participants Follow-up genome sequence Genome sequences implementation independent Infection International Intervention Laboratory less likelihood Limited lineages Maximum likelihood Medical Research Council Migration Molecular epidemiology MOST Mutation nasopharyngeal sample Nasopharyngeal samples nine outbreak PCR test PCR-positive performed Phylogenetic relationship positive processed Public health intervention Quality control quarantine reported Retrospective study Sample SARS-CoV-2 SARS-CoV-2 sequencing Science sequence Sequencing Spike protein Spread study period surveillance data symptomatic the SARS-CoV-2 the spike protein Transmission Travel variants virus WHO whole genome whole genome sequence Whole genome sequencing Zimbabwe [DOI] 10.1016/S2214-109X(21)00434-4 PMC 바로가기 [Article Type] Article
Treatment of COVID-19 in pregnant women: A systematic review and meta-analysisReview article Published on 2021-12-012022-10-05 Journal: European journal of obstetrics, gynecology, and re [Category] Coronavirus, SARS, 임상, 치료법, [키워드] 95% CI Abstract Admission adverse outcome anaesthesia APGAR score Appendix association authors China clinical clinically CNKI collected Comparative Complication country COVID-19 Critical database death defined Diagnosis ECMO Effect effective eligibility eligibility criteria eligible estimate excluded expected General population hospital Hospital admission ICU ICU admission include Infrastructure Interpretation Intervention involved mechanical ventilation Meta-analysis Neonatal Neonatal COVID-19 NICU admission objective outcome outcomes performed pharmacological Pneumonia positive Pregnancy pregnant pregnant women Preterm birth Prevalence prospective cohort provided Randomised controlled trials researcher Result retrospective cohort screened selected Stillbirth Study design Symptom symptomatic systematic literature search systematic review the disease Treatment Trial was performed WHO with COVID-19 women World Health Organization [DOI] 10.1016/j.ejogrb.2021.10.007 [Article Type] Review article
Humoral and Cell-Mediated Immune Response in Colostrum from Women Diagnosed Positive for SARS-CoV-2Clinical Research Published on 2021-12-012022-10-28 Journal: Breastfeeding medicine : the official journal of t [Category] COVID-19, MERS, [키워드] 48 hour acute respiratory syndrome addition antibody Asymptomatic COVID-19 Bilateral breast milk Breastfeeding collected colostrum comparable conducted controls coronavirus COVID-19 cytokine cytokine response disease elevated enzyme-linked immunosorbent evaluate Evolution exhibited humoral immune response IFN-γ IgA IgG IgM IL-10 IL-12 IL-13 IL-2 IL-4 IL-6 IL-8 immune response Inflammatory cytokine Inflammatory marker measure mother multiplex positive provided RBD reactivity Receptor binding domain response SARS-CoV-2 SARS-CoV-2-specific antibody Spike protein statistically significant symptomatic tested the antibody response the SARS-CoV-2 tumor necrosis factor-alpha validation study virus was used were infected were used women [DOI] 10.1089/bfm.2021.0082 PMC 바로가기 [Article Type] Clinical Research
TaqI polymorphism of the VDR gene: aspects related to the clinical behavior of COVID-19 in Cuban patientsCorrespondence Published on 2021-11-302022-11-01 Journal: The Egyptian Journal of Medical Human Genetics [Category] COVID-19, [키워드] alleles association clinical form COVID-19 Cuba determine form Genetic polymorphism Genotype greater Patient patients PCR polymorphism presenting receptor Result risk suffered symptomatic VDR Vitamin D was determined [DOI] 10.1186/s43042-021-00206-4 PMC 바로가기 [Article Type] Correspondence