Peripheral blood – Page 52 – Communicable Diseases Research

Effects of Short-Term Low-Dose Glucocorticoids for Patients with Mild COVID-19

Clinical Study

Published on 2020-09-232022-10-27
Journal: BioMed Research International [Category] COVID-19,

Effects of Short-Term Low-Dose Glucocorticoids for Patients with Mild COVID-19

Clinical Study

Published on 2020-09-232022-10-27
Journal: BioMed Research International [Category] Coronavirus, COVID-19, MERS, SARS,

[키워드] Admission blood lymphocyte CD3+ CD4+ CD4+ T cell CD8+ CD8+ T cell China clearance Clinical outcome conducted COVID-19 COVID-19 case cross-sectional cumulative disease Effect effect size evaluate Final glucocorticoid Glucocorticoids group healthy individuals low-dose lymphocyte Lymphocyte count Methylprednisolone Mild mild COVID-19 patients Negative conversion rate no significant difference nucleic acid objective patients peripheral Peripheral blood peripheral lymphocyte Pharyngeal swab positive Result retrospective returned significantly single-center study statistically significant T cell T cell subset T cells the disease the healthy the patient treatment group treatment groups two groups viral nucleic acid were recorded were used without affecting
[DOI] 10.1155/2020/2854186 PMC 바로가기 [Article Type] Clinical Study

Differential microRNA expression in the peripheral blood from human patients with COVID‐19

Research Article

Published on 2020-09-222022-10-30
Journal: Journal of Clinical Laboratory Analysis [Category] COVID-19, MERS, SARS,

[키워드] acute respiratory syndrome Bioinformatics analysis biological processes blood cell category caused cellular components cluster analysis controls coronavirus coronavirus disease Correlation analysis COVID‐19 COVID‐19 patient COVID‐19 patients COVID‐19 differential expression differentially expressed donors downregulated enrichment analysis expression expression level Extract Gene Expression healthy donors high‐throughput sequencing highest immune response microRNA miRNA miRNA expression miRNAs molecular functions Patient peptidases Peripheral blood protein kinases purified reduction regulate Regulation SARS‐CoV‐2 Sequencing shown target gene the healthy total RNA upregulated viral infection viral replication was performed was reduced
[DOI] 10.1002/jcla.23590 PMC 바로가기 [Article Type] Research Article

Optimising triage procedures for patients with cancer needing active anticancer treatment in the COVID-19 era

Research article

Published on 2020-09-212022-10-05
Journal: ESMO open [Category] SARS, 치료법,

[키워드] active cancer addition Administered age anticancer Asymptomatic case Asymptomatic COVID-19 asymptomatic patient average Breast cancer Cancer candidate Chemotherapy Cohort COVID-19 COVID-19 infection COVID-19 symptoms detect hospital Hospital admission identify IgG positivity IgM IgM and IgG Immunotherapy Infection Most patient Naple Optimising Patient patients Patients with cancer Peripheral blood positive Radiotherapy Rapid rapid serological test Real-time PCR receiving resources Result RT-PCR SARS-CoV-2 SARS-CoV-2 test serological test Serological testing Symptom tested therapy Treatment university
[DOI] 10.1136/esmoopen-2020-000885 [Article Type] Research article

Longitudinal immune profiling reveals key myeloid signatures associated with COVID-19

Research Articles

Published on 2020-09-172022-10-28
Journal: Science Immunology [Category] COVID-19, Fulltext, SARS,

[키워드] alteration Analysis Bone marrow CD14 Cell cellular clinical disease COVID-19 pandemic COVID-19 pathogenesis COVID-19 patient disease driving elevated enzyme exaggerated immune response expression feature Hospital admission hospitalized patient identify IL-6 immune immune profiling immune response immune signature inflammatory component innate immune IP-10 longitudinal marker MCP-1 median modulation monocyte mononuclear cell myeloid cell neutrophil outcome Patient PBMCs Peripheral blood phenotype reveal serum severe disease severity of COVID-19 Support T cell the healthy therapeutic strategy therapy timepoints Whole blood with COVID-19
[DOI] 10.1126/sciimmunol.abd6197 PMC 바로가기 [Article Type] Research Articles

Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans

Research Article

Published on 2020-09-042022-10-28
Journal: Science (New York, N.y.) [Category] COVID-19, MERS, SARS,

[키워드] acute respiratory syndrome affected analyzed Antigen approach Atlanta Bacterial coronavirus Coronavirus disease 2019 correlated COVID-19 COVID-19 patient COVID-19 patients COVID-19 severity disease disease severity expression flow cytometry healthy individual healthy individuals HLA-DR Hong Kong hospitalized COVID-19 patient Human Human immune system human immunity IFN-stimulated genes IFN-α Immune cell immune modulation immune response immune system Immunity immunotype Infection Inflammatory influence information Interferon-α knowledge lack leukocyte mammalian mechanism Mild mononuclear cell myeloid cell parameters Patient PBMC PBMCs performed Peripheral blood plasma plasmacytoid dendritic cells potential therapeutic target Proinflammatory cytokine Rapamycin reduced respond response SARS-CoV-2 Science severe COVID-19 Severe COVID-19 Infection Signaling Single-cell transcriptomics System Systems biology therapeutic interventions TNFSF14 transcriptomics transient expression type I IFNs United States with COVID-19
[DOI] 10.1126/science.abc6261 PMC 바로가기 [Article Type] Research Article

COVID-19-activated SREBP2 disturbs cholesterol biosynthesis and leads to cytokine storm

Article

Published on 2020-09-032022-10-04
Journal: Signal Transduction and Targeted Therapy [Category] Fulltext, SARS, 진단, 치료제,

Prolonged Course of COVID-19-Associated Pneumonia in a B-Cell Depleted Patient After Rituximab

Oncology

Published on 2020-09-022022-10-31
Journal: Frontiers in Oncology [Category] COVID-19,

Isolation, Sequence, Infectivity, and Replication Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2

Research

Published on 2020-09-012022-10-31
Journal: Emerging Infectious Diseases [Category] COVID-19, SARS,

Natural killer cell immunotypes related to COVID-19 disease severity

Research Article

Published on 2020-08-212022-10-28
Journal: Science Immunology [Category] COVID-19, Fulltext, MERS,

[키워드] Activation acute SARS-CoV-2 infection acute viral infection adaptive Analysis Blood Bronchoalveolar lavage Cancer CD56 Cell circulating circulation contribute coronavirus disease COVID-19 COVID-19 disease COVID-19 disease severity COVID-19 patients Defense defined disease pathogenesis disease severity driven by expression Factors flow cytometry hallmark Host host response immunopathology immunotype increase in Inflammatory innate immune innate immune response Last lymphocyte mechanism natural natural killer cell NK cell NK cells Patient patients with moderate Peripheral blood Protein protein-protein interaction provide respond SARS-COV-2 infection severe COVID-19 severe disease severe patients Single-cell RNA sequencing subset understanding viral infection with COVID-19
[DOI] 10.1126/sciimmunol.abd6832 PMC 바로가기 [Article Type] Research Article