Clinical characteristics and survival analysis in critical and non-critical patients with COVID-19 in Wuhan, China: a single-center retrospective case control studyArticle Published on 2020-10-162022-10-04 Journal: Scientific Reports [Category] MERS, SARS, 치료기술, 치료법, 치료제, [키워드] Analysis antibiotic Antibiotics anticoagulation case control study caused Characteristics China clinical Clinical course contributed Corticosteroid COVID-19 COVID-19 patient Critical critical condition critical patient D-dimer demographic elevated Epidemic epidemiological fibrinogen High-sensitivity C-reactive protein Hospitalized hsCRP IL-6 In-hospital death in-hospital mortality Infectious diseases Inpatient Laboratory tests lymphocyte Multivariable regression outbreak outcome Oxygen therapy Patient patient survival patients patients with COVID-19 Platelet positive Predictive qSOFA reported Respiratory tract diseases retrospective risk factor Risk factors single-center SOFA score survival the SARS-CoV-2 Tongji Hospital Treatment Wuhan Wuhan, China [DOI] 10.1038/s41598-020-74465-3 PMC 바로가기 [Article Type] Article
Experience of N-acetylcysteine airway management in the successful treatment of one case of critical condition with COVID-19 A case report6700 Published on 2020-10-162022-10-30 Journal: Medicine [Category] COVID-19, MERS, SARS, [키워드] Acetylcysteine Admission airway airway management anastomotic Antibiotics Antiviral Bacterial infection bronchoalveolar Bronchoalveolar lavage Cancer Case report Chest computed tomography Combination condition Corona cough COVID-19 critical condition cured Deterioration diagnosed discharged Dyspnea endotracheal experience expressed global pandemic Hospitalization hypercapnia IMPROVE intubation invasive respiratory support lesson mechanical ventilation medications NAC New coronavirus New coronavirus pneumonia Novel coronavirus nucleic acid test Patient patients performed Pharyngeal swab Pneumonia Prognosis provided repeated Respiratory failure Respiratory Support secretion severe COVID-19 patients Support symptomatic the patient treated Treatment with COVID-19 [DOI] 10.1097/MD.0000000000022577 PMC 바로가기 [Article Type] 6700
Ciprofloxacin and moxifloxacin could interact with SARS-CoV-2 protease: preliminary in silico analysis시프로플록사신과 목시플록사신은 SARS-CoV-2 프로테아제와 상호작용할 수 있습니다: 예비 in silico 분석Comparative Study Published on 2020-10-152022-09-10 Journal: Pharmacological Reports [Category] MERS, SARS, 치료제, [키워드] active site activities Analysis Antibiotics antiviral activity applied binding Chloroquine ciprofloxacin COVID-19 COVID-19 Main Protease (Mpro) demonstrated docking Evidence gold greater in silico in silico analysis Interaction Ligand lower binding energy M pro molecular molecular docking molecular dynamics moxifloxacin nelfinavir positive controls Protein protein interaction protein interactions Research Result SARS-CoV-2 shown tested were used with COVID-19 [DOI] 10.1007/s43440-020-00169-0 PMC 바로가기 [Article Type] Comparative Study
Unfortunate Outcomes in Patients With SARS-CoV-2 Superimposed on Pneumococcal PneumoniaInternal Medicine Published on 2020-10-142022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory syndrome Antibiotics Bacterial infection clinical condition complicate coronavirus COVID-19 COVID-19 outbreak death Deterioration Dexamethasone disease Health Hypoxemia implication management organ Oxygenation Patient PCR pneumococcal pneumococcal antigen Pneumonia polymerase chain positive Remdesivir SARS-CoV-2 the disease the patient the United State treated Urine virus [DOI] 10.7759/cureus.10939 PMC 바로가기 [Article Type] Internal Medicine
Spontaneous pneumomediastinum, pneumopericardium, pneumothorax and subcutaneous emphysema in patients with COVID-19 pneumonia, a case reportCase Report Published on 2020-10-072022-10-30 Journal: Journal of Cardiothoracic Surgery [Category] Coronavirus, MERS, SARS, [키워드] acute respiratory distress syndrome Antibiotics Case report clinician Combination complication of COVID-19 COVID-19 COVID-19 pneumonia described determine emphysema highlight intubation Laboratory laboratory data mechanical ventilation multiple comorbidities Oxygen therapy pathophysiology Patient patients with COVID-19 Pneumomediastinum Pneumonia positive pressure ventilation Predictive required risk factor serious complication Severe acute respiratory syndrome Spontaneous Spontaneous pneumomediastinum Spontaneous pneumopericardium steroid [DOI] 10.1186/s13019-020-01308-7 PMC 바로가기 [Article Type] Case Report
A case report of toxic epidermal necrolysis (TEN) in a patient with COVID-19 treated with hydroxychloroquine: are these two partners in crime?Case Report Published on 2020-10-062022-11-01 Journal: Clinical and Molecular Allergy : CMA [Category] COVID-19, [키워드] Activation Adverse Adverse Drug Reaction (ADR) ALDEN Algorithm Algorithm Antibiotics Atypical Blister calculated cardiometabolic Case report caused clinical evidence COVID 19 COVID-19 COVID-19 positive patient Cutaneous detect Dexamethasone drug epidermal extension highest Hydroxychloroquine immune system knowledge lesion less low-molecular-weight-heparin Manifestations mucous membrane Necrolysis off-label Other outcome pandemic Paracetamol Patient patient with COVID-19 pharmacovigilance potassium canrenoate Rash reaction regimen respiratory retrieved SARS-CoV- 2 SCORTEN Score Severe Cutaneous Adverse Reactions (SCAR) Stevens–Johnson Syndrome (SJS) syndrome the patient total body Toxic Epidermal Necrolysis (TEN) toxicities treated virus widespread [DOI] 10.1186/s12948-020-00133-6 PMC 바로가기 [Article Type] Case Report
Recommendations for antibacterial therapy in adults with COVID-19 – an evidence based guidelineGuidelines Published on 2020-10-012022-11-01 Journal: Clinical microbiology and infection : the official [Category] COVID-19, MERS, SARS, [키워드] addressed Admission antibacterial therapy antibiotic Antibiotic treatment antibiotic use Antibiotics Antigen Antimicrobial therapy assessment Bacterial Bacterial infection Bacterial infections bacterial pathogen Bacterial pathogens Blood Co-infection COVID-19 COVID-19 pandemic COVID-19 patients Culture development diagnose disease effort Epidemiology Evidence FIVE guidelines Hospitalization Hospitalized hospitalized COVID-19 patients inflammatory markers methodology occurred Patient patients with COVID-19 performed Perspective pneumococcal Pneumonia Policy Prevent Prospective Study recommendation reported respiratory infection risk SARS-CoV-2 secondary bacterial Secondary infection sputum Support Symptom treat Treatment Ventilator-associated pneumonia with COVID-19 working [DOI] 10.1016/j.cmi.2020.09.041 PMC 바로가기 [Article Type] Guidelines
Clinical features of patients with coronavirus disease 2019 from a designated hospital in Beijing, China중국 베이징의 지정 병원에서 2019년 코로나바이러스 환자의 임상적 특징Observational Study Published on 2020-10-012022-09-11 Journal: Journal of medical virology [Category] MERS, SARS, 임상, 진단, 치료제, [키워드] age albumin analyzed Antibiotics antiviral drugs Beijing Chest computed tomography China clinical Clinical and laboratory data Clinical characteristics Clinical features Clinical outcome clinical outcomes Clusters collected Comorbidities Comorbidity Computed tomography coronavirus coronavirus disease Coronavirus disease 2019 Corticosteroid COVID-19 demographic demographic data designated Hospital in Beijing. discharged dosage enrolled eosinophil Eosinophil count erythrocyte sedimentation erythrocyte sedimentation rate Factor feature Fever gamma globulin hospital hypertension IMPROVE Incubation period interquartile range IQR Laboratory laboratory data laboratory findings laboratory-confirmed SARS-CoV-2 infection less lymphocyte marker Mild neutrophil neutrophil count Older age outcomes Patient patients with COVID-19 poor prognosis potential risk reduce SARS-CoV-2 SARS-COV-2 infection sedimentation rate Serum ferritin severe symptoms severity significantly still hospitalized Symptom Symptoms the mean the median therapy Treatment Wuhan Wuhan, China [DOI] 10.1002/jmv.25966 PMC 바로가기 [Article Type] Observational Study
Could Respiratory Fluoroquinolones, Levofloxacin and Moxifloxacin, Prove to be Beneficial as an Adjunct Treatment in COVID-19?호흡기 플루오로퀴놀론, 레보플록사신 및 목시플록사신이 COVID-19의 보조 치료제로 유용할 수 있습니까?Article Published on 2020-10-012022-09-11 Journal: Archives of medical research [Category] SARS, 신약개발, 치료제, [키워드] adjunct adjuncts anti-inflammatory drug Anti-inflammatory drugs Antibiotics antimicrobial agents antiretroviral drug Antiviral antiviral action antiviral activity attenuation binding broad spectrum characterized Chloroquine ciprofloxacin CMV community-acquired pneumonia comparable Concentration COVID-19 COVID-19 pandemic Cytokines derivative effective therapy exhibiting Fluoroquinolone HCV HIV HSV-1 immunomodulatory immunomodulatory properties in silico Infection Inflammatory response inhibit SARS-CoV-2 levofloxacin Lungs management moxifloxacin nelfinavir papovavirus pharmacokinetic Pneumonia pro-inflammatory cytokines prodrome protease Protease inhibitor quinoline Replication researcher respiratory respiratory infections safety profile SARS-CoV-2 SARS-CoV-2 replication shown therapeutic agent therapeutic agents treat Treatment vaccinia virus [DOI] 10.1016/j.arcmed.2020.06.004 PMC 바로가기 [Article Type] Article
Rhino-Orbital Mucormycosis Associated With COVID-19Internal Medicine Published on 2020-09-302022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory syndrome Admission Antibiotics Bacterial Brain coronavirus Coronavirus disease 2019 Course COVID-19 Culture Diabetic Extensive fungal fungal disease Fungal infection fungal infections hyphae Infection invasive malar male Methylprednisolone MRI Mucormycosis nasal oral oseltamivir orbit over paranasal Patient patient with COVID-19 patients with COVID-19 physician polymerase chain positive Region retrobulbar RT-PCR SARS-CoV-2 tissue Treatment [DOI] 10.7759/cureus.10726 PMC 바로가기 [Article Type] Internal Medicine