Designing of cytotoxic and helper T cell epitope map provides insights into the highly contagious nature of the pandemic novel coronavirus SARS-CoV-21001 Published on 2020-09-162022-10-28 Journal: Royal Society Open Science [Category] COVID-19, [키워드] analyses antigen processing Belonging Betacoronavirus computational tools conserved Contact contagious coronavirus creating Cytokine storm drug effective epitope Epitope-based vaccine Epitopes helper T cell humans Hyperactivation immune response immunogenic immunoinformatics immunopathology in vitro information novel novel coronavirus SARS-CoV-2 pandemic pathogen pathway Protein Proteins provide SARS-CoV-2 SARS-CoV-2 protein SARS-CoV-2 proteome Spread Stage survival symptomatic and asymptomatic T cell T cell epitopes the SARS-CoV-2 Transmission Treatment unique Vaccine Vaccines Viral protein [DOI] 10.1098/rsos.201141 PMC 바로가기 [Article Type] 1001
A network-based explanation of why most COVID-19 infection curves are linearPhysical Sciences Published on 2020-09-152022-10-29 Journal: Proceedings of the National Academy of Sciences of [Category] COVID-19, MERS, [키워드] Above applicability characteristic compartmental epidemiological model compartmental model confirmed case Contact contagious country COVID-19 COVID-19 epidemic COVID-19 infection Critical epidemiological estimate example explain explained feature growth household size Immunity Infection infection prevalence linear lockdown lockdowns mathematical mean-field (well mixed) approximation measure National network theory nonpharmaceutical intervention NPIs observation observé occur offer pandemic parameters Precision Probability question reached reduce reveal Significance social contact networks suppressed the epidemic the United State Traditional transmission rate [DOI] 10.1073/pnas.2010398117 PMC 바로가기 [Article Type] Physical Sciences
Update of the current knowledge on genetics, evolution, immunopathogenesis, and transmission for coronavirus disease 19 (COVID-19)Review Published on 2020-09-122022-10-29 Journal: International Journal of Biological Sciences [Category] COVID-19, MERS, SARS, [키워드] ACE2 acute respiratory disease acute respiratory syndrome angiotensin-converting enzyme 2 assist bat coronavirus caused Cell China clinical feature contagious coronavirus coronavirus disease coronavirus-mediated human disease Coronaviruses COVID-19 COVID-19 outbreak COVID-19 pandemic Epidemics Evolution Genetic variation genetics genomic Host hosts Human Immunity Immunopathogenesis infect knowledge MERS Middle East molecular responses mutations pandemic Phylogenetic Protein respiratory syndrome coronavirus response SARS-CoV SARS-CoV-2 SARS-CoV-2 genomics silent Spread target tissue Transmission transmission route Transmission routes virus WHO World Health Organization zoonotic [DOI] 10.7150/ijbs.48812 PMC 바로가기 [Article Type] Review
Reusable Face Masks as Alternative for Disposable Medical Masks: Factors that Affect their Wear-ComfortArticle Published on 2020-09-112022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] Affect Antiviral breathability commenced contagious coronavirus country COVID−19 deteriorate dramatic increase fabric mask face Face mask Face masks Factor Mask mask comfortability medical masks outbreak Panic reusable mask selected transfer Trial Variation virus [DOI] 10.3390/ijerph17186623 PMC 바로가기 [Article Type] Article
A Telemedicine Approach to Covid-19 Assessment and TriageReview Published on 2020-09-102022-10-30 Journal: Medicina [Category] COVID-19, SARS, [키워드] acute respiratory distress assessment Asymptomatic caused contagious cough Course COVID-19 disease distress droplet evaluated global pandemic health care workers maintain manifestation Mild moderate morbidity and mortality nasal Novel coronavirus occur Patient patients Pneumonia provide quarantine RNA social distancing spread to syndrome telehealth Telemedicine Transmission Triage upper respiratory symptoms viral disease while [DOI] 10.3390/medicina56090461 PMC 바로가기 [Article Type] Review
Tuberculosis and COVID-19: Lessons from the Past Viral Outbreaks and Possible Future OutcomesResearch Article Published on 2020-09-052022-10-31 Journal: Canadian Respiratory Journal [Category] COVID-19, MERS, SARS, [키워드] accelerated addressed Affect approach article assumed changes in clinical evolution contagious contribute coronavirus COVID-19 COVID-19 pandemic database Diagnosis diagnostic reliability disease Diseases eligibility essential element Future Host immune responses inclusion criteria infection control Infectious disease Influenza lesson other coronaviruses outbreak Pathogens pathway Patient predict public health Registered Result risk SARS-CoV SARS-CoV virus SARS-CoV-2 searched second synergism TB patients Travel Trial Tuberculosis vaccination Vaccine viral epidemics viral respiratory infection [DOI] 10.1155/2020/1401053 PMC 바로가기 [Article Type] Research Article
Mitigating Coronavirus Induced Dysfunctional Immunity for At-Risk Populations in COVID-19: Trained Immunity, BCG and “New Old Friends”Immunology Published on 2020-09-042022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] Mycobacterium obuense animal anti-SARS-CoV-2 vaccine BCG Characteristics Combined contagious coronavirus SARS-CoV-2 coronavirus vaccine Coronaviruses COVID-19 cytokine dysfunctional immune response effective effort hallmark help high risk highly pathogenic IMM-101 immune cells immune response Immunity immunological immunopathological induced infectious agents knowledge Mycobacterium Novel coronavirus observation overcome pandemic patients with COVID-19 Population PROTECT representing Respiratory illness response risk Safe SARS severe COVID-19 disease Spread systemic level trained immunity Vaccine Vaccine development Vaccines [DOI] 10.3389/fimmu.2020.02059 PMC 바로가기 [Article Type] Immunology
SARS-CoV-2/COVID-19 and advances in developing potential therapeutics and vaccines to counter this emerging pandemicReview Published on 2020-09-022022-10-28 Journal: Annals of Clinical Microbiology and Antimicrobials [Category] COVID-19, SARS, [키워드] affecting antibody antiviral drugs bats catastrophic China city conducted contagious coronavirus disease Coronaviruses country COVID-19 CoVs deaths develop Diagnosis diagnostics drugs Dyspnea effective Evolution Extensive Fever Genome genus Betacoronavirus globe help Immunotherapeutics Infection MERS-CoV molecular molecular basis Novel coronavirus pandemic pandemic virus Phylogenetic analysis Pneumonia Research RNA virus SARS-CoV SARS-CoV-2 SARS-CoV-2 virus severely infected patient Spread Symptom the disease the SARS-CoV-2 therapeutic therapeutic option Therapeutics turn Vaccine Vaccine development Vaccines virus Wuhan [DOI] 10.1186/s12941-020-00384-w PMC 바로가기 [Article Type] Review
COVID-19: beta-thalassemia subjects immunised?Research article Published on 2020-09-012022-10-05 Journal: Medical Hypotheses [Category] SARS, 유전자 메커니즘, [키워드] analyzed Beta thalassemia beta-thalassemia contagious coronavirus correlated correlation COVID-19 COVID-19 infection COVID19 demonstrated disease Evolution Favipiravir heme hemoglobin heterozygote hypothese Immunity immunization Italian region Italy Multiple linear regression Novel coronavirus Pneumonia population prevalence prevalences Regression Research respiratory distress respiratory infectious disease Sardinia SARSCoV-2 Statistics subject virus [DOI] 10.1016/j.mehy.2020.109827 [Article Type] Research article
Tumor markers as an entry for SARS-CoV-2 infection?SARS-CoV-2 감염에 대한 항목으로서의 종양 표지자?Review Published on 2020-09-012022-08-31 Journal: The Febs Journal [Category] MERS, SARS, 바이오마커, 임상, 진단, [키워드] absence ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 Basigin binding Cancer Cancer patients caused CD147 Clinical finding Clinical findings contagious coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients death drugs Emmprin entry receptor globe Health crisis higher risk identifying Invasion marker Multiple organ damage open organ damage our times Patient Prevent Protein public health crisis receptor respiratory SARS-CoV-2 SARS-COV-2 infection severe disease Spike protein Spread target protein Treatment Tumor tumor markers Viral viral spike virus while [DOI] 10.1111/febs.15499 PMC 바로가기 [Article Type] Review