Middle East respiratory syndrome coronavirus (MERS-CoV) neutralising antibodies in a high-risk human population, Morocco, November 2017 to January 2018Research Published on 2019-11-282022-10-31 Journal: Eurosurveillance [Category] Coronavirus, Fulltext, 조류인플루엔자, [키워드] Arabian Peninsula carried collected Contact cross dromedaries Dromedary ELISA Evidence General population global public health high-risk population Human individual Infection MERS MERS-CoV MERS-CoV infection Middle East Middle East respiratory syndrome Coronavirus Morocco neutralisation test neutralising antibody occurred one individual over PRNT protocol provide questionnaire reduction reported respiratory syndrome coronavirus Result risk factor serological evidence serum sample Transmission were used World Health Organization zoonosis zoonotic zoonotic transmission [DOI] 10.2807/1560-7917.ES.2019.24.48.1900244 PMC 바로가기 [Article Type] Research
Antibodies and vaccines against Middle East respiratory syndrome coronavirusReview Published on 2019-06-062022-10-31 Journal: Emerging Microbes & Infections [Category] Coronavirus, MERS, [키워드] Antibody Response candidate vaccine clinical trials coronavirus country Critical Fatality rate global public health highlight humoral immune response include infected individuals mechanism medical intervention MERS-CoV MERS-CoV infection MERS-CoV S protein Middle East monoclonal antibody notable Novel coronavirus outbreak Protective provided reservoir respiratory syndrome coronavirus S glycoprotein Saudi Arabia spike glycoprotein Spread target therapeutic agent translate Vaccine viral entry [DOI] 10.1080/22221751.2019.1624482 PMC 바로가기 [Article Type] Review
Neutralizing Monoclonal Antibodies as Promising Therapeutics against Middle East Respiratory Syndrome Coronavirus InfectionReview Published on 2018-11-302022-10-28 Journal: Viruses [Category] Coronavirus, MERS, [키워드] approved Combination distribution domain effective Epitopes Fatality rate global public health Immunotherapy mAb mAbs MERS MERS-CoV MERS-CoV infection Middle East Middle East Respiratory Syndrome Virus mutant Neutralizing neutralizing monoclonal antibodies neutralizing monoclonal antibody Passive Prophylactic RBD respiratory selective the spike protein therapeutic therapeutic agent Therapeutics therapy Vaccine viruses [DOI] 10.3390/v10120680 PMC 바로가기 [Article Type] Review
Lack of serological evidence of Middle East respiratory syndrome coronavirus infection in virus exposed camel abattoir workers in Nigeria, 2016Research Article Published on 2018-08-092022-10-31 Journal: Eurosurveillance [Category] Coronavirus, Fulltext, 조류인플루엔자, [키워드] abattoir Camel coronavirus Evidence global public health Human Infection investigated MERS MERS-CoV MERS-CoV RNA Middle East nasal swab neutralising antibody Nigeria occupational exposure ranged repeated reported respiratory syndrome coronavirus Result serological evidence serology tested Urine virus Weekly zoonotic zoonotic disease zoonotic threat zoonotic transmission [DOI] 10.2807/1560-7917.ES.2018.23.32.1800175 PMC 바로가기 [Article Type] Research Article
MERS-CoV Accessory ORFs Play Key Role for Infection and PathogenesisResearch Article Published on 2017-08-222022-10-29 Journal: mBio [Category] Coronavirus, [키워드] absence Accessory Activation addition Cell coronavirus Coronaviruses CoV Critical driven by dysregulated Frame function global public health highlight host responses IFN implication in vivo models Infection Inflammation initial interferon live vector vaccines MERS-CoV MERS-CoV infection Middle East modulation mutant mutant virus mutants offer ORF ORF3 ORF5 outbreak Pathogenesis pathway platform Protein rapid response replication attenuation reverse genetics robust role SARS- and MERS-CoV SARS-CoV strain Surveillance syndrome target therapeutic Therapeutic treatment Treatment Vaccine vaccine platform viral replication while zoonotic pathogen [DOI] 10.1128/mBio.00665-17 PMC 바로가기 [Article Type] Research Article
Interventions to reduce zoonotic and pandemic risks from avian influenza in AsiaArticle Published on 2017-04-202023-05-31 Journal: The Lancet. Infectious Diseases [Category] Fulltext, 조류인플루엔자, [키워드] Avian global public health H5N1 H7N9 Influenza Live poultry markets one health pandemic poultry trade prevention zoonotic [DOI] 10.1016/S1473-3099(15)00502-2 PMC 바로가기 [Article Type] Article
Infectious diseases epidemic threats and mass gatherings: refocusing global attention on the continuing spread of the Middle East Respiratory syndrome coronavirus (MERS-CoV)Commentary Published on 2016-09-072022-10-28 Journal: BMC Medicine [Category] Coronavirus, MERS, [키워드] Community condition Control coronavirus country creating death disease Diseases Donor Ebola virus emerging disease Epidemic Epidemic transmission Epidemics game global public health Hajj Infectious disease Infectious diseases International Kingdom Korean mass Mass gathering MERS case MERS-CoV middle Middle East occurred outbreak resource respiratory respiratory syndrome coronavirus Rio Saudi Arabia South South Korea Spread Surveillance syndrome the WHO threat Threats Transmission West WHO World Health Organization Zika virus [DOI] 10.1186/s12916-016-0686-3 PMC 바로가기 [Article Type] Commentary
Middle East respiratory syndrome coronavirus (MERS-CoV) entry inhibitors targeting spike proteinArticle Published on 2014-10-142022-11-01 Journal: Virus research [Category] Coronavirus, MERS, [키워드] Antiviral effect binding cell entry Combination coronavirus disease effective Entry inhibitor Fatality rate fusion inhibitor global public health Infection inhibitor inhibitors inhibitory laboratory-confirmed MERS MERS case MERS-CoV MERS-CoV entry MERS-CoV infection Middle East Middle East respiratory syndrome Coronavirus neutralizing antibody nonspecific Novel coronavirus outbreak peptide Prevent prophylactic strategy RBD Receptor-binding domain Replication respiratory syndrome coronavirus S protein S1 subunit S2 subunit Safe six-helix bundle Spike protein syndrome synergistic the receptor-binding domain the S1 subunit therapeutic treat Treatment virus [DOI] 10.1016/j.virusres.2014.10.007 PMC 바로가기 [Article Type] Article
Hospital Outbreak of Middle East Respiratory Syndrome CoronavirusArticle Published on 2013-10-172022-11-01 Journal: The New England Journal of Medicine [Category] Coronavirus, Fulltext, MERS, [키워드] 95% CI 95% confidence interval Care case caused Chest clade Cluster Contact cough Critical died different Fever Gastrointestinal symptom global public health Health Health care worker Hemodialysis Hospitalized household contact included Incubation period infections information intensive care units isolate laboratory-confirmed measure median medical record MERS-CoV MERS-CoV infection Middle East morbidity occur onset of symptom Patient person-to-person transmission Pneumonia remained reported respiratory respiratory syndrome coronavirus RNA Saudi Arabia sequenced Shortness of breath Transmission World Health Organization [DOI] 10.1056/NEJMoa1306742 PMC 바로가기 [Article Type] Article