Therapeutic strategies against COVID-19Article Published on 2020-04-282023-07-01 Journal: Acta bio-medica : Atenei Parmensis [Category] SARS, [키워드] antiviral drug COVID-19 Drug repurposing immunomodulatory drug SARS-CoV-2 [DOI] 10.23750/abm.v91i3.10450 PMC 바로가기
Combating devastating COVID-19 by drug repurposingArticle Published on 2020-04-172023-06-16 Journal: International journal of antimicrobial agents [Category] MERS, SARS, [키워드] coronavirus CoV, coronavirus COVID-19 Drug repurposing MERS-CoV, Middle East respiratory syndrome coronavirus SARS-CoV-2 SARS-CoV, severe acute respiratory syndrome coronavirus [DOI] 10.1016/j.ijantimicag.2020.105984 PMC 바로가기
Teicoplanin: an alternative drug for the treatment of COVID-19?Editorial Published on 2020-04-012022-10-05 Journal: International journal of antimicrobial agents [Category] SARS, 신약개발, [키워드] acute respiratory syndrome antibiotic appear China conserved coronavirus COVID-19 Drug repurposing Efficacy Efficiency first stage human cells in vitro infections inhibit lack MERS-CoV Middle East Novel coronavirus Outbreaks Patient Pneumonia Potential treatment Remdesivir respiratory syndrome coronavirus ribavirin Ritonavir SARS-CoV-2 shown specific treatment Spread staphylococcal Teicoplanin the epidemic therapeutic Transmission treat Treatment viral life cycle virus Wuhan [DOI] 10.1016/j.ijantimicag.2020.105944 [Article Type] Editorial
Predicting commercially available antiviral drugs that may act on the novel coronavirus (SARS-CoV-2) through a drug-target interaction deep learning modelCommunications Published on 2020-03-302022-10-31 Journal: Computational and Structural Biotechnology Journal [Category] COVID-19, [키워드] addition antiretroviral Antiviral agents antiviral drug Atazanavir China complex component coronavirus COVID-19 deep learning drug Drug repurposing drug-target effective HIV Human immunodeficiency virus identify incidence rate Infection inhibit SARS-CoV-2 inhibitory potency Interaction Kaletra lack medication molecule MT-DTI Novel coronavirus predicted Prevent proteinase Remdesivir Replication Ritonavir SARS-CoV-2 target tested the SARS-CoV-2 treat Treatment treatment strategy Viral protein was used Wuhan [DOI] 10.1016/j.csbj.2020.03.025 PMC 바로가기 [Article Type] Communications
Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2Article Published on 2020-03-162022-10-04 Journal: Cell Discovery [Category] 신약개발, 치료제, [키워드] 2019 novel coronavirus 2019-nCoV 2019-nCoV/SARS-CoV-2 acute respiratory syndrome Analysis antiviral drug bioinformatics Comparative genomics conserved coronavirus de novo drug drug combination Drug discovery Drug repurposing drug target drugs effective effective drug emodin enrichment analysis Epidemics exposure highest Human human cell lines identify identity Interaction melatonin methodology morbidity and mortality Novel coronavirus nucleocapsid protein nucleotide sequence offer platform Protein–protein interaction Proteomic analysis reduce regions representing SARS-CoV SARS-CoV-2 sequence identity target transcriptomics whole genome [DOI] 10.1038/s41421-020-0153-3 PMC 바로가기 [Article Type] Article
Facts and Myths: Efficacies of Repurposing Chloroquine and Hydroxychloroquine for the Treatment of COVID-19Review Published on 2020-01-012023-07-05 Journal: Current drug targets [Category] SARS, [키워드] 2019-nCoV clinical trials COVID-19 Drug repurposing Hydroxychloroquine pandemic [DOI] 10.2174/1389450121666200617133142 [Article Type] Review
Artemisinin and its derivatives; ancient tradition inspiring the latest therapeutic approaches against malariaarticle Published on 2019-06-302024-09-01 Journal: Future Med Chem [Category] 말라리아, [키워드] ART derivatives Artemisinin Drug repurposing extraction malaria resistance [Article Type] article
Identification and in vivo Efficacy Assessment of Approved Orally Bioavailable Human Host Protein-Targeting Drugs With Broad Anti-influenza A ActivityOriginal Research Published on 2019-06-052023-06-08 Journal: Frontiers in Immunology [Category] Fulltext, 신종인플루엔자, [키워드] animal models antiviral (H1N1 and H3N2) activity Drug repurposing host protein-targeting drugs influenza A virus [DOI] 10.3389/fimmu.2019.01097 PMC 바로가기 [Article Type] Original Research
Drug Repurposing Identifies Inhibitors of Oseltamivir-Resistant Influenza VirusesArticle Published on 2016-03-012023-06-23 Journal: Angewandte Chemie (International ed. in English) [Category] 신종인플루엔자, [키워드] Computational chemistry Drug discovery Drug repurposing influenza viruses neuraminidase [DOI] 10.1002/anie.201511361 PMC 바로가기
Molecular Evidence for the Inverse Comorbidity between Central Nervous System Disorders and Cancers Detected by Transcriptomic Meta-analyses전사체 메타 분석에 의해 발견된 중추신경계 장애와 암 사이의 역병환에 대한 분자적 증거Research Article Published on 2014-02-202022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] (Alzheimer's disease Alzheimer's disease Analysis Author biological processe biological processes cancers Candidates causes CENTRAL CNS CNS disorder Colorectal Comorbidity complex disorders conditions conducted contribute decrease Degradation deregulated deregulation described disease disorder disorders downregulated downregulation driven by Drug repurposing drug treatment drug treatments epidemiological Evidence expected expression Factors Gene Genetic genetic factors Hypothesis incidence inverse lung mechanism Meta-analysis molecular nervous observé opposite overlap Parkinson's Disease pathway Pathways Patient PIN1 Probability progression promote Prostate protective effect Protein related risk Schizophrenia System tested transcriptomic Treatment understanding upregulated upregulation Wnt [DOI] 10.1371/journal.pgen.1004173 PMC 바로가기 [Article Type] Research Article