Impact of COVID-19 pandemic and the lockdown on invasive meningococcal diseaseResearch Note Published on 2020-08-272022-10-27 Journal: BMC Research Notes [Category] COVID-19, MERS, [키워드] addressed association correlation COVID-19 COVID-19 pandemic described disease Enhancing flu French Haemophilus influenzae Impact Infection invasive Invasive meningococcal disease involved isolate isolates lockdown mandatory National Reference Centre objective Respiratory presentations Result SARS-CoV-2 SARS-CoV-2, COVID-19 Secondary bacterial infections significantly increased Surveillance These data typing vaccination [DOI] 10.1186/s13104-020-05241-9 PMC 바로가기 [Article Type] Research Note
Analysis of Inactivation of SARS-CoV-2 by Specimen Transport Media, Nucleic Acid Extraction Reagents, Detergents, and FixativesVirology Published on 2020-08-242022-10-30 Journal: Journal of Clinical Microbiology [Category] COVID-19, MERS, SARS, [키워드] acid addition approach assessment biosafety clinical diagnostics coronavirus coronavirus SARS-CoV-2 COVID-19 COVID-19 pandemic Critical diagnostic diagnostics Effectiveness element etiological agent evaluated extraction filtration FIVE fixative fixatives Health inactivation Infectious virus investigated Laboratory lysis buffers molecular extraction reagents nucleic acid extraction pandemic participant Pathogens public health emergency rapid response reagent Research researchers risk safety testing SARS-CoV-2 Scientific community Seven similar study specimen transport tubes tested These data Treatment virus inactivation work [DOI] 10.1128/JCM.01713-20 PMC 바로가기 [Article Type] Virology
Factors associated with resilience among non-local medical workers sent to Wuhan, China during the COVID-19 outbreakResearch Article Published on 2020-08-242022-10-27 Journal: BMC Psychiatry [Category] Coronavirus, MERS, [키워드] 2019 novel coronavirus analyzed Anxiety Anxiety,depression asked Care Complete composed coping coping style correlated COVID-19 COVID-19 outbreak Depression develop disease Factor HADS Health highest hospital Intervention Local Medical workers Multiple Nurse outbreak physician provided regression analysis Resilience respond respondent response Result scale significantly Support survey These data Wuhan Wuhan, China [DOI] 10.1186/s12888-020-02821-8 PMC 바로가기 [Article Type] Research Article
COVID-19 Outbreak and Physical Activity in the Italian Population: A Cross-Sectional Analysis of the Underlying Psychosocial MechanismsPsychology Published on 2020-08-212022-10-31 Journal: Frontiers in Psychology [Category] COVID-19, [키워드] activity addition Analysis Anxiety approach confinement country COVID-19 COVID-19 pandemic deleterious effect Effect equation European Giving Government healthcare Home-based exercise Infectious disease integrated theoretical model Intention investigated Italian Italy lockdown lombardy measure Measures Model novel coronavirus disease outbreak pandemic physical physical activity Physical inactivity Prevalence Protective Psychosocial public health measure quarantine recommendations significantly higher Social distance social distancing Spread These data variable [DOI] 10.3389/fpsyg.2020.02100 PMC 바로가기 [Article Type] Psychology
Oscillatory Dynamics in Infectivity and Death Rates of COVID-19Research Article Published on 2020-08-182022-10-29 Journal: mSystems [Category] COVID-19, [키워드] Analysis collected collected data computer modeling condition contribute coronavirus disease country COVID-19 death rate Dynamics Epidemics follow-up study Guidance hospital Hypothesis India infections Infectivity Local observation Rate reduced reported SARS-HCoV-2 Spread Stress the disease These data turn while [DOI] 10.1128/mSystems.00700-20 PMC 바로가기 [Article Type] Research Article
COVID-19 and Inflammatory Bowel Disease: Patient Knowledge and Perceptions in a Single Center SurveyArticle Published on 2020-08-132022-10-30 Journal: Medicina [Category] COVID-19, MERS, [키워드] 95% CI 95% confidence interval Active disease Administered affected age Anxiety center China Clinical characteristics country COVID-19 Crohn disease disease evaluate FIVE Health care IBD increasing age individual Inflammatory bowel disease knowledge male management material measure Measures Most patient Odds ratio Older age pandemic Patient patients Perception Prevalence Prevention measures promote questionnaire reported Result SARS-COV-2 infection spreading survey These data variable [DOI] 10.3390/medicina56080407 PMC 바로가기 [Article Type] Article
A point mutation decouples the lipid transfer activities of microsomal triglyceride transfer protein점 돌연변이는 마이크로솜 트리글리세리드 전달 단백질의 지질 전달 활동을 분리합니다Research Article Published on 2020-08-062022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Affect ApoB ApoB-containing lipoprotein ApoB-containing lipoproteins Apolipoprotein B Apolipoprotein B-containing lipoprotein Apolipoprotein B-containing lipoproteins assembly B-lp B-lps bind block blood vessels cardiovascular cardiovascular disease circulation complex conserved Critical crystal structure cytoplasmic lipid droplet cytoplasmic lipid droplets disease Disruption drug design dyslipidemia dyslipidemias Embryo endogenous lipid fat malabsorption feasible G863V G863V mttp mutant protein G863V mutant protein glycine growth growth defects growth retardation growth retardation) health condition heterodimeric highlight Human human MTP humans hydrophobic identify inhibitor insect Insects intestinal fat malabsorption L475P Lipid lipid transfer activity lipids Lipoproteins metabolism microsomal triglyceride transfer protein Missense mutation modeling morphology Mtp MTP complex MTP triglyceride transfer activity MTTP mutant mutants Mutation opacity phenotype Phospholipids plasma lipoproteins Point mutation power Prevent Protein reduce reported required residue secretion selective selective inhibition Support synthesis Therapeutic approach These data tissues transfer Transport treat Triglyceride triglycerides valine vertebrates wall yolk yolk opacity yolk syncytial layer YSL zebrafish [DOI] 10.1371/journal.pgen.1008941 PMC 바로가기 [Article Type] Research Article
Transferrin receptor 1 levels at the cell surface influence the susceptibility of newborn piglets to PEDV infectionResearch Article Published on 2020-07-302022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, [키워드] activate Ammonium antibody Caco-2 caused Cell Clustering deficiency epidemic diarrhea expression Extracellular HEK 293T impair in vitro in vivo infect Infection infections inhibited interact intestinal intestinal epithelial cell intestinal epithelial cells iron accumulation iron deficiency mechanism Newborn Older over-expressed PEDV Phosphorylation promote provide receptor reduce reveal S1 protein susceptibility susceptible therapy These data tissue Transferrin Treatment tyrosine virus was increased [DOI] 10.1371/journal.ppat.1008682 PMC 바로가기 [Article Type] Research Article
A Message from the Human Placenta: Structural and Immunomodulatory Defense against SARS-CoV-2Review Published on 2020-07-252022-10-31 Journal: Cells [Category] COVID-19, SARS, [키워드] acute respiratory syndrome autophagy caused Cell complications coronavirus coronavirus disease COVID-19 COVID-19 patients Cytokine storm Defense Evidence expression global public health Human immune defense immune response immunomodulatory Infection interferon type III mechanism mechanisms message miRNA mitigate modulation mother Neonatal COVID-19 NF-κB pathway nuclear occur outbreak pandemic pathogen pathology pathway physical physical barrier Placenta placental potential molecular Pregnancy pregnant women preterm births Proteases receptor reducing SARS-CoV-2 SARS-CoV-2 transmission Signaling Stillbirth the interferon These data tissue Transmission type III vertical transmission viral infections Virus-host interaction [DOI] 10.3390/cells9081777 PMC 바로가기 [Article Type] Review
Structural analysis of the SARS-CoV-2 methyltransferase complex involved in RNA cap creation bound to sinefunginArticle Published on 2020-07-242022-10-04 Journal: Nature Communications [Category] SARS, 치료제, [키워드] acute respiratory syndrome Analysis Antiviral agents antiviral therapy catalytic site cofactor comparison complex coronavirus COVID-19 pandemic Drug discovery enzyme expresse feasible information inhibitor involved methyltransferase Protein RNA RNA methyltransferase SARS-CoV SARS-CoV-2 SARS-CoV-2 viruses stability the SARS-CoV-2 therapy These data Viral RNA virus X-ray crystallography Zika [DOI] 10.1038/s41467-020-17495-9 PMC 바로가기 [Article Type] Article