Animal experiments show impact of vaccination on reduction of SARS-CoV-2 virus circulation: A model for vaccine development?SARS-CoV-2 바이러스 순환 감소에 대한 백신 접종의 영향을 보여주는 동물 실험: 백신 개발 모델?Review Published on 2021-09-012022-09-12 Journal: Biologicals : journal of the International Associa [Category] SARS, 진단, [키워드] animal Animal experiment animal model animal models Blood bronchoalveolar clinical development clinical trials COVID-19 disease Efficacy eight experiments exposure Exposure experiments Intention Lungs nasal swab neutralizing antibody predicted reduced reduction retrieved SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 virus shown Standardization tested Transmission trials vaccination Vaccine Vaccine development vaccine platform Viral load viral replication Viral RNA viral shedding virus excretion [DOI] 10.1016/j.biologicals.2021.08.001 PMC 바로가기 [Article Type] Review
Predictors of mortality, ICU hospitalization, and extrapulmonary complications in COVID-19 patientsObservational Study Published on 2021-09-012022-10-05 Journal: Infectious diseases now [Category] SARS, 임상, [키워드] absence Acute liver injury acute renal injury age C-reactive protein (CRP Cancer caused chronic pulmonary disease Comorbidity Complication complications COVID-19 COVID-19 patient CRP death Dementia diabetes diagnosis of COVID-19 died disease eight examined Extrapulmonary Extrapulmonary COVID-19 Factor FIVE France Frequency hemoglobin Hospitalization ICU ICU patient ICU Patients independent major coronavirus Male sex males median median age Mortality MOST neurological non-ICU patients Non-survivors Observational cohort study occurred Older age outbreak outcome oxygen supply Patient patients Platelet pulmonary diseases renal required retrospective risk factor SARS-CoV-2 serum creatinine severe COVID-19 single-center Venous Thromboembolism [DOI] 10.1016/j.idnow.2021.07.002 PMC 바로가기 [Article Type] Observational Study
News media narratives of Covid-19 across 20 countries: Early global convergence and later regional divergenceResearch Article Published on 2021-09-012022-10-28 Journal: PLoS ONE [Category] COVID-19, SARS, [키워드] AIDS analysed articles Asia benefit country Dengue fever distill eight English evaluate evidenced FIVE generate global pandemic independent Lyme disease media nCoV news media North America objective pandemic peak Prevalence provided Region repeated researchers Result risk SARS-CoV-2 second Spread Volume Wuhan [DOI] 10.1371/journal.pone.0256358 PMC 바로가기 [Article Type] Research Article
Systematic Review and Meta-Analysis of Tocilizumab Therapy versus Standard of Care in over 15,000 COVID-19 Pneumonia Patients during the First Eight Months of the Pandemic대유행의 첫 8개월 동안 15,000명 이상의 COVID-19 폐렴 환자에서 Tocilizumab 치료와 표준 치료에 대한 체계적인 검토 및 메타 분석Review Published on 2021-08-302022-09-12 Journal: International Journal of Environmental Research an [Category] SARS, 진단, [키워드] “cytokine storm” adjusted adopted Analysis anti-IL-6 anti-IL-6 therapy articles Bacterial infection Bacterial infections benefit case-control studies case-control study concomitant corticosteroid therapy controls Corticosteroid COVID-19 COVID-19 case Cytokine storm database death rate early stage early stages Effectiveness Efficacy eight estimate estimates heterogeneity ICU admission inception Infection lack management mechanical ventilation medRxiv Meta-analysis meta-regression Month mortality rate open label pandemic Patient performed Protective protective effect randomized trial reduction review robust SARS-CoV-2 virus SARS-CoV-2 virus infection severe COVID-19 SSRN Standard Standard of care steroid steroid use Subgroup analyses subgroup analysis subsequent suggested survival systematic review systematic review and meta-analysis therapeutic Tocilizumab Toxicity virus infection were assessed widespread [DOI] 10.3390/ijerph18179149 PMC 바로가기 [Article Type] Review
Dietary Habits and Lifestyle During Coronavirus Pandemic Lockdown: Experience From LebanonNutrition Published on 2021-08-302022-10-31 Journal: Frontiers in Nutrition [Category] COVID-19, [키워드] activity changes in claimed conducted COVID-19 cross-sectional dietary habit eating habits eight experience food Food security form Google highlight impacted Lebanon less lifestyle behaviors lockdown mental health pandemic per day physical activity Psychosocial quarantine question questionnaire reported sedentary time significant decrease significant increase Sleep sleep quality Stress [DOI] 10.3389/fnut.2021.730425 PMC 바로가기 [Article Type] Nutrition
Targeting CoV-2 spike RBD and ACE-2 interaction with flavonoids of Anatolian propolis by in silico and in vitro studies in terms of possible COVID-19 therapeuticsArticle Published on 2021-08-302022-10-29 Journal: Turkish Journal of Biology [Category] COVID-19, [키워드] ACE-2 addition ADME Analysis AutoDock binding energy caffeic acid calculated Compound COVID-19 COVID-19 therapeutics distribution drug-likeness drugs eight ELISA exhibited ferulic acid hesperetin highest in silico in vitro in vitro study inhibitory inhibitory effect Interaction investigated metabolism molecular docking pinocembrin Propolis Protein RBD receptors S1 protein SARS-CoV-2 screening test targeting the SARS-CoV-2 virus were used [DOI] 10.3906/biy-2104-5 PMC 바로가기 [Article Type] Article
Antibiotics Use and Its Knowledge in the Community: A Mobile Phone Survey during the COVID-19 Pandemic in BangladeshArticle Published on 2021-08-292022-10-27 Journal: Antibiotics [Category] COVID-19, [키워드] age antibiotic awareness Antibiotic resistance antibiotic use Antibiotics Community conducted COVID-19 COVID-19 pandemic Descriptive analysis division Effects eight elevated General population illness illnesses knowledge male Medicine Mobile pandemic Participants performed Randomly recall recent illness reported survey use of antibiotics were assessed were recorded [DOI] 10.3390/antibiotics10091052 PMC 바로가기 [Article Type] Article
Influence of SARS-CoV-2 Virus Infection on the Course of Psoriasis during Treatment with Biological DrugsObservational Study Published on 2021-08-272022-10-04 Journal: Medicina [Category] MERS, SARS, 임상, [키워드] Administered Affect analyzed Area Biological biological drugs chain comparable control group Course COVID-19 COVID-19 disease COVID-19 pandemic diagnosed drug effective therapy eight Hospitalization index infected with SARS-CoV-2 influence material Mild observé Patient PCR positive psoriasis psoriatic arthritis reaction required Result RT-PCR SARS-CoV-2 SARS-COV-2 infection skin lesions statistically telephone contact therapy time Treatment [DOI] 10.3390/medicina57090881 PMC 바로가기 [Article Type] Observational Study
Artificial Intelligence Predicts Severity of COVID-19 Based on Correlation of Exaggerated Monocyte Activation, Excessive Organ Damage and Hyperinflammatory Syndrome: A Prospective Clinical Study인공 지능, 과장된 단핵구 활성화, 과도한 장기 손상 및 과염증 증후군의 상관 관계를 기반으로 COVID-19의 심각도 예측: 전향적 임상 연구Immunology Published on 2021-08-272022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 바이오마커, 진단, [키워드] Accuracy Admission Alanine alanine aminotransferase Algorithms ALT Analysis analyzed applied artificial artificial intelligence aspartate Aspartate aminotransferase AST biochemical analyses Biomarker C-reactive protein C-reactive protein (CRP chemokine chemokines clinical COVID-19 COVID-19 patient COVID-19 patients creatinine CT scan CT scans cytokine Cytokines D-dimer damage develop eight fibrinogen forest gamma interferon Glucose healthy control HMGB1 hospitalized COVID-19 patient identify IL-6 intelligence interferon Laboratory Lactate lactate dehydrogenase LDH Logistic regression Lungs Macrophage macrophage derived cytokine management mDC methodology MIG moderate moderate disease monocyte monokine objective on admission parameter predict prediction prediction models predictor Prognostic factor Prognostic factors Prognostic value Prospective provide Random forest reduce mortality Result severe disease severely ill patient severely ill patients severity severity of COVID-19 significantly higher support vector machine the disease the patient [DOI] 10.3389/fimmu.2021.715072 PMC 바로가기 [Article Type] Immunology
Prepandemic Risk Factors of COVID‐19‐Related Concerns in Adolescents During the COVID‐19 PandemicSpecial Section‐Issue Published on 2021-08-262022-10-30 Journal: Journal of Research on Adolescence [Category] COVID-19, SARS, [키워드] activity Adolescence Adolescent adverse outcomes age concern COVID‐19 COVID‐19 demonstrated developmental eight examined Factor identify investigated longitudinal mental health outcomes pandemic predicted Prevent problems protective factor reported Result risk Stress were assessed [DOI] 10.1111/jora.12651 PMC 바로가기 [Article Type] Special Section‐Issue