Prospective – Page 58 – Communicable Diseases Research

Recent Advancements in the Diagnosis, Prevention, and Prospective Drug Therapy of COVID-19

Review

Published on 2020-07-102022-10-04
Journal: Frontiers in Public Health [Category] MERS, 신약개발,

Development and Clinical Evaluation of a Web-Based Upper Limb Home Rehabilitation System Using a Smartwatch and Machine Learning Model for Chronic Stroke Survivors: Prospective Comparative Study

스마트워치와 머신러닝 모델을 이용한 만성 뇌졸중 생존자를 위한 웹 기반 상지 재활 시스템 개발 및 임상 평가: 전향적 비교 연구

Original Paper

Published on 2020-07-092022-08-13
Journal: JMIR mHealth and uHealth [Category] 임상,

[키워드] accelerometer Accuracy activity Algorithm artificial intelligence assessment Beck Care chronic chronic stroke clinical clinical evaluation clinical outcomes Clinical research clinical study Comparative conducted control group Convolutional neural network COVID-19 pandemic data set data sets determine develop development drop Efficacy enrolled evaluate extremity facilitate feasibility flexion Follow-up Frequency function functional group Gyroscope Health care health care systems home home care home-based rehabilitation IMPROVE internal rotation inventory joint machine learning ML model Model motor Motor Function objective participant Participation Patient performed physical Physical therapy Prospective range of motion recent recognize Registration rehabilitation rehabilitation exercises Research Result ROM service shoulder joint shown Smartphone smartwatch statistical analysis stroke survivor Survivors System Test the mean therapy Treatment two group two groups upper Upper extremity user was used wearable device wearable technology Wolf
[DOI] 10.2196/17216 PMC 바로가기 [Article Type] Original Paper

Azithromycin added to hydroxychloroquine for patients admitted to intensive care due to coronavirus disease 2019 (COVID-19)—protocol of randomised controlled trial AZIQUINE-ICU

Study Protocol

Published on 2020-07-082022-10-29
Journal: Trials [Category] COVID-19, SARS,

[키워드] added addition Administered Admission allergy Azithromycin benefit clinical cohort of patient Combination Controlled trial coronavirus disease coronavirus SARS-CoV-2 COVID-19 COVID-19 infection criteria Deterioration disease dose double-blind drug early administration Efficacy febrile disease groups hospital Hydroxychloroquine hypothesise ICU ICU admission in vitro include Infection intensive care intubation limit limitation lung mechanical ventilation mechanically ventilated Mortality not differ novel Novel coronavirus outcome outcomes pathway Patient patients Placebo Pregnancy Prevent prevented progressive COVID-19 Prospective randomised randomised controlled trial RCT receive Respiratory failure SARS-CoV-2 secondary severe COVID-19 Standard of care survival susceptible Symptom Treatment Trial viral replication
[DOI] 10.1186/s13063-020-04566-x PMC 바로가기 [Article Type] Study Protocol

Targeting GM-CSF in COVID-19 Pneumonia: Rationale and Strategies

Immunology

Published on 2020-07-032022-11-01
Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS,

[키워드] administration alveolar macrophage animal model binding blockade blunting cells circulating Clinical improvement clinical trial compassionate use COVID-19 Cytokine release syndrome death described driven by FDA approval GM-CSF healthy controls help Hospitalization hyperinflammation IL-6 Increased Inflammatory cytokine Inflammatory response inflammatory signaling interferon-γ intranasal intravenous dose involved lung damage Macrophage macrophages mavrilimumab mechanical ventilation Mild symptom monoclonal antibodies monoclonal antibody MOST outcomes Oxygenation patients with COVID-19 placebo-controlled trial produced proliferation Prospective provided Randomized rationale receptor Respiratory failure respiratory infections SARS-CoV-2 Severe case severe pneumonia Signaling Strategy syndrome T-cells targeting tested treated Trial while
[DOI] 10.3389/fimmu.2020.01625 PMC 바로가기 [Article Type] Immunology

Olfactory and Gustatory Outcomes in COVID-19: A Prospective Evaluation in Nonhospitalized Subjects

Special Section on COVID-19

Published on 2020-06-302022-10-29
Journal: Otolaryngology--Head and Neck Surgery [Category] COVID-19, MERS, SARS,

The burden, admission, and outcome of COVID-19 in Africa: protocol for a systematic review and meta-analysis

Review

Published on 2020-06-152022-10-31
Journal: Emerging Microbes & Infections [Category] COVID-19, MERS, SARS,

Prevalence and Recovery From Olfactory and Gustatory Dysfunctions in Covid-19 Infection: A Prospective Multicenter Study

Original Articles

Published on 2020-06-122022-10-28
Journal: American Journal of Rhinology & Allergy [Category] COVID-19, Fulltext, SARS,

Characteristics and outcomes of pregnant women admitted to hospital with confirmed SARS-CoV-2 infection in UK: national population based cohort study

Research

Published on 2020-06-082022-10-28
Journal: The BMJ [Category] COVID-19, Fulltext, SARS,

[키워드] 95% confidence interval acute respiratory syndrome Admission Cohort cohort study Comorbidities coronavirus Critical care death died ethnic group Factor fetal FIVE groups Guidance hospital Hospital admission identify incidence Infant Infants Infection ISRCTN MOST mother National Neonatal obese objective obstetric unit outcome outcome measure outcomes participant positive Pregnancy pregnant women Preterm birth proportion Prospective Rate Respiratory Support Result SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA setting Social distancing measure Stillbirth System tested Transmission transmission of SARS-CoV-2 urgent investigation women
[DOI] 10.1136/bmj.m2107 PMC 바로가기 [Article Type] Research

Adding Colchicine to the Antiretroviral Medication – Lopinavir/Ritonavir (Kaletra) in Hospitalized Patients with Non-Severe Covid-19 Pneumonia: A Structured Summary of a Study Protocol for a Randomized Controlled Trial

Letter

Published on 2020-06-052022-10-29
Journal: Trials [Category] Coronavirus, SARS,

[키워드] 1:1 added Adding anti-inflammatory effect Antibiotics anticipated antioxidant antioxidants antiretroviral blinded both group CDC center change Clinical course Clinical improvement Colchicine component Consensus Controlled COVID-19 COVID-19 infection COVID-19 patients digoxin dissemination dosage double blind double-blind study element enrolled equation estimate Final GFR glomerular filtration rate group help Hospital stay hospitalized COVID-19 patients hypersensitivity hypoxic in both group infected with COVID-19 Inflammation inflammatory disorders Inpatient interleukin-8 intubation invasive Iran Kaletra kidney transplant recipients Lopinavir/ritonavir lung Lung CT MDA mechanism Minerals Nasopharyngeal swab National number objective outcome oxidative stress Oxygenation pandemic parallel group participant pathologic pathway Patient patients percentage Pneumonia positive Prospective protocol QTc randomised randomised controlled trial randomization Randomized Rate Ratio receive recruited recruitment reducing reduction Registered RT -PCR Sample size serum creatinine status Tehran time tomography Trace element treat treated Treatment two group two groups Vitamin website WHO guideline with COVID-19
[DOI] 10.1186/s13063-020-04455-3 PMC 바로가기 [Article Type] Letter

Controlled, double-blind, randomized trial to assess the efficacy and safety of hydroxychloroquine chemoprophylaxis in SARS CoV2 infection in healthcare personnel in the hospital setting: A structured summary of a study protocol for a randomised controlled trial

Letter

Published on 2020-06-032022-10-29
Journal: Trials [Category] Coronavirus, SARS,

[키워드] 1:1 95% CI absence addition administration of hydroxychloroquine Admission aerosol-generating procedures allergy analyzed Anesthesia antibody approved ARMS assigned balanced randomization blind Cancer Cantabria carried CDC Cell Chemoprophylaxis clinical Clinical data clinically coated Committee comparator Comparator group computer-generated control group Controlled Controlled clinical trial Controlled trial coronavirus COVID COVID-19 criteria CURB current detect Determination disease dissemination double blind double-blind dropout rate Efficacy Efficacy and safety element ELISA kit Emergency Endocrine estimate Ethics Euroimmun Evidence evidence of Germany GRADE greater group Health Health authority health-care healthcare personnel Healthcare professional healthcare professionals heart heart failure help hematological high risk hospital Hydroxychloroquine hydroxychloroquine sulfate hygiene Hypothesis ICU IDT IgA IgG IgM and IgG immune immunodeficiency in vitro incidence include Infection inhibit intensive care unit Intervention investigator kidney lactation liver measure Measures Medicine Negative PCR neurological New York number observation period outcome participant PCR performed Personal protective equipment Placebo positive positive SARS-CoV-2 PCR positive serology Pregnancy presenting Prevalence Primary outcome probes product professional Prophylaxis Prospective PROTECT Protective protocol Psychiatric randomised randomised controlled trial randomization Randomized randomized trial RCT receive recruitment reduce reported responsible risk RT-PCR Sample size SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 PCR sequence Seroconversion serological serology severity Significant single center single-center study social distancing Spain Spanish Standard Statistical power status Study protocol subject Support Symptom symptomatic and asymptomatic Tablet Takara Taking Tamoxifen Transmission Treatment two-tailed university Vaccine virus website while
[DOI] 10.1186/s13063-020-04400-4 PMC 바로가기 [Article Type] Letter