Early Adoption of Longitudinal Surveillance for SARS-CoV-2 among Staff in Long-Term Care Facilities: Prevalence, Virologic and Sequence Analysis장기 요양 시설 직원의 SARS-CoV-2 종단 감시 조기 채택: 유병률, 바이러스 및 염기서열 분석Research Article Published on 2021-11-102022-09-12 Journal: Microbiology Spectrum [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus adoption advanced age Analysis Asymptomatic asymptomatic infections Care Characteristics Cohort collected Comorbidities Complete contributed coronavirus COVID-19 death declining epidemiological Epidemiology event Genetic Genetic epidemiology genomes genomic Impact incidence individuals Infection infections Infectious disease Infectious virus less Long-term care longitudinal nasal swab Nasopharyngeal swab nasopharyngeal swabs notable outcome pandemic pathogen performed persistence presence of comorbidities Prevalence risk factor SARS-CoV-2 SARS-CoV-2 dynamics SARS-COV-2 infection SARS-CoV-2 pandemic SARS-CoV-2 PCR sequenced severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spread staff subset Support Surveillance surveillance testing symptomatic the SARS-CoV-2 The United States Transmission Transmission dynamics transmission of SARS-CoV-2 unique United States Viral RNA virus vRNA Workplace [DOI] 10.1128/Spectrum.01003-21 PMC 바로가기 [Article Type] Research Article
Diagnostic Approaches for COVID-19 and Its Associated ComplicationsReview Published on 2021-11-092022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] Acute kidney injury advanced age advancement ALT analyzed article AST Coagulopathy Complication COVID-19 COVID-19 and complications COVID-19 diagnosis COVID-19 pandemic COVID-19 patients COVID-19 sampling and testing COVID-19 testing COVID-19-related complication CRIPSR technology in COVID-19 diagnosis CRISPR CT-scan CURB-65 Cytokine storm D-dimer death determine diabetes diagnosed Diagnosis diagnostic elevated FDA gold standard help hospital hypertension IgM and IgG IL-6 increased risk indicated initial intensive care lactate dehydrogenase Mortality nasopharyngeal obesity organ damage Oropharyngeal patients Pneumonia Severity Index polymerase chain Protein protocol required RT-PCR SARS-COV-2 infection scale Serological testing severe COVID-19 patient sputum Symptom transcriptase treat with COVID-19 [DOI] 10.3390/diagnostics11112071 PMC 바로가기 [Article Type] Review
The immune-neuroendocrine system in COVID-19, advanced age and rheumatic diseasesReview article Published on 2021-11-012022-10-05 Journal: Autoimmunity reviews [Category] SARS, 바이오마커, [키워드] activate advanced age Autoimmune Autoimmune rheumatic diseases Central nervous system COVID-19 COVID-19 infection COVID-19 pandemic favor homeostasis Immune-neuroendocrine system Inflammatory maintain multiple study Older older people Patient patients with comorbidity Perspective Population rheumatic disease Rheumatic diseases Stress subject viral infection [DOI] 10.1016/j.autrev.2021.102946 [Article Type] Review article
Strong Association of Angiotensin Converting Enzyme-2 Gene Insertion/Deletion Polymorphism with Susceptibility to SARS-CoV-2, Hypertension, Coronary Artery Disease and COVID-19 Disease MortalityArticle Published on 2021-10-272022-10-30 Journal: Journal of Personalized Medicine [Category] COVID-19, [키워드] 95% CI ACE ACE gene ACE1-angiotensin-converting enzyme 1 ACE2 ACE2-angiotensin-converting enzyme 2 addition advanced age age allele allelic amplification Analysis angiotensin angiotensin-converting enzyme 2 Artery association bind Control controls Coronary Coronary artery disease correlation COVID-19 COVID-19 mortality COVID-19 patient COVID-19 patients COVID-19 severity diabete distribution facilitate Frequency functional Gender gene polymorphism Genotype genotyping group Health healthy control host cell hypertension I/D I/D polymorphism indicated Infection insertion/deletion International ischemic heart disease Mortality Mutation outbreak P -value Pathogenesis pathogenesis of COVID-19 PCR protective factor public health receptor reported Result rs4240157 SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome coronavirus 2 severe COVID-19 severity significant difference Spike protein Strong susceptibility to SARS-CoV-2 susceptible T2D targeted intervention virus entry with COVID-19 [DOI] 10.3390/jpm11111098 PMC 바로가기 [Article Type] Article
Peripheral infiltration of remdesivir in 3 patients with COVID-19: Case series and discussionCOVID-19 환자 3명에서 렘데시비르의 말초 침윤: 사례 시리즈 및 토론Case Reports Published on 2021-10-252022-09-11 Journal: American journal of health-system pharmacy : AJHP [Category] SARS, 치료제, [키워드] accelerated advanced age affected Case report Case series case sery caused Complication coronavirus disease Coronavirus disease 2019 COVID-19 drug edema exploration Factor Formulation hematoma hyaluronidase infiltration information infusion Injections Injury intrinsic male medication occurred outcome Pain palpation pandemic Patient patients with COVID-19 peripheral provided redness Remdesivir resulting specific treatment swelling Symptom the patient Toxicity treated Volume [DOI] 10.1093/ajhp/zxab197 PMC 바로가기 [Article Type] Case Reports
Clinical and Demographic Profile of COVID-19 Patients: A Tertiary Level Hospital-Based Study From Northeast IndiaInternal Medicine Published on 2021-10-192022-10-31 Journal: Cureus [Category] COVID-19, [키워드] Admission advanced age Analysis Asymptomatic Care clinical Clinical presentations clinical profile Cohort Comorbidity complications Contact cough COVID-19 COVID-19 case COVID-19 cases COVID-19 pandemic cross-sectional death demographic Diabetes Mellitus disease enrolled Fatality rate Fever global healthcare healthcare facility help higher risk hospital hypertension India individual Infection information laboratory feature laboratory-confirmed Level majority male material median age northeast india outbreak outcome Patient Patient care patients presenting profile profiles progression of disease Result SARS-CoV-2 Shortness of breath Tertiary the patient Treatment variations was collected with COVID-19 Wuhan, China [DOI] 10.7759/cureus.18881 PMC 바로가기 [Article Type] Internal Medicine
Clonal hematopoiesis is associated with risk of severe Covid-19클론 조혈은 심각한 Covid-19의 위험과 관련이 있습니다Article Published on 2021-10-132022-09-10 Journal: Nature Communications [Category] MERS, SARS, 변종, 유전자 메커니즘, 진단, 치료기술, [키워드] Acquired advanced age characterized Clostridium Clostridium difficile Cohort consortia disease Genomics Haematopoiesis Hematopoiesis increased risk individual Infection infections Infectious diseases Inflammatory Korean malignant diseases Memorial Mutation outcome overall survival Patient patient data pro-inflammatory profile progenitor cell progenitor cells risk SARS-CoV-2 severe COVID-19 Severe infection severe infections significantly solid tumor somatic mutation somatic mutations survival Tumor [DOI] 10.1038/s41467-021-26138-6 PMC 바로가기 [Article Type] Article
Obesity Correlates With Pronounced Aberrant Innate Immune Responses in Hospitalized Aged COVID-19 Patients비만은 입원한 노인 COVID-19 환자의 비정상적인 선천성 면역 반응과 관련이 있습니다Comparative Study Published on 2021-10-112022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adaptive immune response Admission Admissions advanced age age aging Antibody titers BMI caused changes in Chronic low-grade inflammation circulating Concentration coronavirus coronavirus disease Coronavirus disease 2019 correlated COVID-19 cytokine cytokine response Cytokines death defined dysregulated elevated Frequency hospitalizations hospitalized COVID-19 patient hospitalized COVID-19 patients host response IgG antibody IgG antibody titers immune Immune cell immune cells immune responses individual Infection Inflammatory cytokine inflammatory cytokine production Innate Innate immunity innate response intensive care intensive care unit mediators mitogen monocyte Monocytes obesity occur patients Prevalence respiratory response responsible risk risk factor Risk factors SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe coronavirus disease severe disease significant negative correlation subset These data [DOI] 10.3389/fimmu.2021.760288 PMC 바로가기 [Article Type] Comparative Study
Clinical impact of blood pressure variability in patients with COVID-19 and hypertensionCOVID-19 및 고혈압 환자에서 혈압 변동성의 임상적 영향Article Published on 2021-10-012022-09-11 Journal: Blood pressure monitoring [Category] MERS, SARS, 바이오마커, [키워드] 95% CI 95% confidence interval advanced age age analyzed arterial pressure blood pressure C-reactive protein calculated CK-MB clinical Clinical outcome clinical outcomes coefficient Coefficient of variation coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients Cox regression analysis creatine creatine kinase Creatine kinase-MB creatinine CRP defined enrolled groups hazard ratio Hospital mortality hypertension in-hospital mortality investigated mean arterial pressure N-terminal NT-proBNP Older Patient patients hospitalized patients with COVID-19 peptide significantly systemic inflammation the median Variability Variation with COVID-19 [DOI] 10.1097/MBP.0000000000000544 PMC 바로가기 [Article Type] Article
Can a modified-simplified pulmonary embolism severity index (m-sPESI) be used to predict the need for intensive care in hospitalized COVID-19 patients?수정-단순 폐색전증 중증도 지수(m-sPESI)를 사용하여 입원한 COVID-19 환자의 집중 치료 필요성을 예측할 수 있습니까?Article Published on 2021-10-012022-09-11 Journal: Journal of Thrombosis and Thrombolysis [Category] MERS, 바이오마커, [키워드] acute respiratory syndrome advanced age age Analysis approach AUC C-reactive protein C-reactive protein (CRP CAD Can Care cause Chain Reaction clinical manifestation clinical manifestations clinician coronavirus disease Coronavirus disease 2019 Coronavirus-2 Course COVID-19 COVID-19 disease COVID-19 infection COVID-19 patient COVID-19 patients detect develop diagnosis of COVID-19 disease examined female fibrinogen Health Organization Healthcare provider healthcare providers hemoglobin Hospitalized hospitalized COVID-19 hospitalized patients ICU admission identify imperative intensive care intensive care unit lab male malignancy mechanical ventilatory support Mild moderate moderate to severe morbidity Mortality multivariable logistic regression Multivariable logistic regression analysis nasal pandemic Patient patients PCR PESI Pharyngeal swab polymerase chain polymerase chain reaction positive predict pulmonary Pulmonary thromboembolism respiratory respiratory symptoms risk risk factor Risk factors SARS-CoV-2 scoring system sensitivity Severe acute respiratory syndrome severe acute respiratory syndrome-associated coronavirus-2 Severe case severe respiratory symptoms severity significantly higher single center specificity SPESI the disease the patient thrombosis Treatment troponin Troponin-I Univariate analysis Validity ventilatory support WHO with COVID-19 World Health Organization [DOI] 10.1007/s11239-021-02405-7 PMC 바로가기 [Article Type] Article