Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Among Skilled Nursing Facility Residents and Staff Members-Los Angeles County, August-September 2020전문 요양 시설 입소자와 직원 사이의 중증 급성 호흡기 증후군 코로나바이러스 2의 혈청 유병률-로스앤젤레스 카운티, 2020년 8월-9월Article Published on 2022-02-012022-09-11 Journal: The Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 All participant All participants asymptomatic infection Chain Reaction conducted coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 database determine enrolled facility identify Los Angele Los Angeles Nasopharyngeal swab nasopharyngeal swab sample Nursing pandemic participant PCR polymerase chain polymerase chain reaction positive positive SARS-CoV-2 PCR Prevalence recruited resident respiratory SARS-CoV-2 SARS-CoV-2 antibodies SARS-COV-2 infection SARS-CoV-2 infections serology Seroprevalence seroprevalence survey serum serum sample serum samples severe acute respiratory syndrome Coronavirus Skilled nursing facilities skilled nursing facility staff Surveillance [DOI] 10.1093/infdis/jiab281 PMC 바로가기 [Article Type] Article
Early assessment of the safety and immunogenicity of a third dose (booster) of COVID-19 immunization in Chinese adults중국 성인을 대상으로 한 코로나19 3차 접종(부스터)의 안전성 및 면역원성 조기 평가Clinical Trial Published on 2022-02-012022-09-11 Journal: Frontiers of medicine [Category] COVID19(2023년), MERS, SARS, 임상, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 All participants analyzed Antibody titer Antibody titers BBIBP-CorV booster booster immunization booster vaccination cellular chemokine chemokines Chinese CHO cells coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 cytokine Cytokines dose effective elicited Endpoint exploratory study heterologous vaccine homologous or heterologous humoral immune response humoral immune responses immune responses Immunity immunization immunization schedule immunogenicity inactivated increase individuals Inducing initial majority Mild Neutralizing antibody titer neutralizing antibody titers Open-label open-label trial pandemic participant populations Protein respiratory response restored Safe Safety safety profile SARS-CoV-2 SARS-CoV-2 vaccine Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus strength Support systemic reactogenicity Trial vaccination Vaccine Vero Cell while [DOI] 10.1007/s11684-021-0914-x PMC 바로가기 [Article Type] Clinical Trial
Comparing Immune Responses to Inactivated Vaccines against SARS-CoV-2 between People Living with HIV and HIV-Negative Individuals: A Cross-Sectional Study in ChinaHIV와 HIV 음성 개인 사이의 SARS-COV-2에 대한 비활성화 백신에 대한 면역 반응 비교 : 중국의 단면 연구Comparative Study Published on 2022-01-282022-09-01 Journal: Viruses [Category] 진단, [키워드] adverse event adverse events All participants antibody antigen-specific T-cell immune response blood sample Blood samples China Chinese Diagnosis first and second dose HIV HIV-negative immune response immunogenicity inactivated inactivated SARS-CoV-2 vaccines individual individuals Neutralizing activity neutralizing activity responses against authentic SARS-CoV-2 Participants people living with HIV PLWH Prevalence receiving recruited response SARS-CoV-2 SARS-CoV-2 IgG antibody SARS-CoV-2 vaccine SARS-CoV-2 vaccines second dose self-reported adverse events Seropositivity severity sociodemographic factors T-cell tested time interval total antibody specific to SARS-CoV-2 Vaccine with HIV [DOI] 10.3390/v14020277 PMC 바로가기 [Article Type] Comparative Study
University population-based prospective cohort study of SARS-CoV-2 infection and immunity (SARSSURV-ULiège): a study protocolSARS-CoV-2 감염 및 면역에 대한 대학 인구 기반 전향적 코호트 연구(SARSSURV-ULiège): 연구 프로토콜Article Published on 2022-01-252022-09-11 Journal: BMJ Open [Category] SARS, 진단, 치료기술, [키워드] activity All participant All participants Antibody Response Antibody responses Antibody testing approval blood sample Blood samples cohort study collected Complete COVID-19 COVID-19 pandemic detect determine Epidemiology Ethics ethics committee Evidence flexible higher education immune response Immunity immunology incidence Infection lack magnitude management medical histories MONITOR Neutralising Antibodies neutralising antibody participant Phase 1 Phase 2 population-based cohort positive Potential Prevalence profiles prospective cohort study protocol amendment public health questionnaire Rapid test rapid test result reference number Registered required Research Research Ethics Research Ethics Committee respond risk Risk assessment Risk management RT-qPCR Safe Saliva SARS-CoV-2 SARS-CoV-2 antibody testing SARS-COV-2 infection serological serological test Seroprevalence Stage student study period Study protocol submitted university university hospital vaccination Vaccine hesitancy Weekly [DOI] 10.1136/bmjopen-2021-055721 PMC 바로가기 [Article Type] Article
Impact of pre-event testing and quarantine on reducing the risk of COVID-19 epidemic rebound: a modelling studyCOVID-19 전염병 반동의 위험 감소에 대한 사전 이벤트 테스트 및 검역소의 영향 : 모델링 연구Research Article Published on 2022-01-242022-09-10 Journal: BMC Infectious Diseases [Category] SARS, 치료기술, [키워드] adjusted affected Against All participants assumed benefit caused Chain Reaction China Community confirmed case Contact Coverage COVID-19 COVID-19 epidemic effective Epidemic examined feasible followed by growth Guangdong Impact increase Infection infections influx International Intervention Large-scale event lead Local mathematical mathematical model Mathematical modelling new infections occur participant Participants participated PCR polymerase chain polymerase chain reaction Prevalence prohibition quarantine reducing Result risk risk of COVID-19 SARS-CoV-2 SARS-CoV-2 transmission scenario Sensitivity analyses supplementary material Testing the epidemic the SARS-CoV-2 Travel Universal virus transmission [DOI] 10.1186/s12879-021-06963-2 PMC 바로가기 [Article Type] Research Article
Thromboelastometry demonstrates endogenous coagulation activation in nonsevere and severe COVID-19 patients and has applicability as a decision algorithm for intervention혈전탄성측정법은 중증이 아닌 중증 COVID-19 환자에서 내인성 응고 활성화를 보여주고 중재를 위한 결정 알고리즘으로 적용 가능Observational Study Published on 2022-01-142022-09-12 Journal: PLoS ONE [Category] 임상, 진단, [키워드] Accuracy Activation age Algorithm All participants applicability blood sample Blood samples calculated Clotting time Coagulation COVID-19 COVID-19 case COVID-19 patient Decision tree examined exhibited extrinsic fibrinogen form functional Functional assessment groups healthy control healthy controls hypercoagulability Intervention intrinsic parameter participant Patient POLE positive qRT-PCR reduced reported SARS-CoV-2 severe COVID-19 severe COVID-19 patient severe COVID-19 patients severe forms of COVID-19 Severe patient severe patients severity significantly suggested tested therapeutic intervention thrombotic [DOI] 10.1371/journal.pone.0262600 PMC 바로가기 [Article Type] Observational Study
Different decay of antibody response and VOC sensitivity in naïve and previously infected subjects at 15 weeks following vaccination with BNT162b2BNT162b2 백신 접종 후 15주에 경험이 없는 피험자와 이전에 감염된 피험자에서 항체 반응 및 VOC 감수성의 상이한 붕괴Research Published on 2022-01-082022-09-10 Journal: Journal of Translational Medicine [Category] 변종, 진단, [키워드] administration All participants antibody Antibody Response applied assays BNT162b2 boost BTN162b2 vaccine Clinical characteristics comparable COVID-19 COVID-19 vaccine cross-neutralizing antibodies D614G demonstrated dose dropped Effectiveness ELISA enrolled expected highlight IgG Immunity infected with SARS-CoV-2 investigated Italy kinetic Kinetics Kruskal–Wallis test Mild naïve naïve subject naïve subjects neutralization assays neutralization titer Neutralizing activity Neutralizing antibodies neutralizing response outcomes pandemic Participants pseudovirus RBD-specific IgG recalled recipient reducing remained Result SARS-CoV-2 SARS-CoV-2 infected subject SARS-COV-2 infection SARS-CoV-2 variants SARS-CoV-2 VOCs second dose second wave sensitivity subject supplementary material the SARS-CoV-2 These data two group two groups vaccination Vaccine vaccine dose variants of concern VoC waning immunity [DOI] 10.1186/s12967-021-03208-3 PMC 바로가기 [Article Type] Research
Feasibility of SARS-CoV-2 Surveillance Testing Among Children and Childcare Workers at German Day Care Centers A Nonrandomized Controlled Trial독일 데이케어 센터의 아동 및 보육 종사자를 대상으로 한 SARS-CoV-2 감시 테스트의 타당성 비무작위 통제 시험Controlled Clinical Trial Published on 2022-01-042022-09-10 Journal: JAMA Network Open [Category] 임상, 진단, 치료기술, [키워드] 95% CI acceptance Administered age All participant All participants assigned Asymptomatic Care center Chain Reaction children children’s health clinical closure conducted continuous surveillance Controlled Controlled trial COVID-19 pandemic Day day care Day Care Centers dropout Effect Efficacy eligible feasibility Feasibility study feasible female finding Germany highest identify Importance individual Infection involved limit maintain mathematical mathematical model measure median module nasal swab nonrandomized objective on children oropharyngeal swabs pandemic parents participant participated Perception Point polymerase chain polymerase chain reaction Prevent Primary outcome Primary outcomes protocol Questionnaires Registration registry Relevance Result Saliva SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 surveillance SARS-CoV-2 testing Secondary infection secondary infections setting setup Spread Surveillance surveillance testing swabbing Testing twice weekly Viral viral spread was used worker [DOI] 10.1001/jamanetworkopen.2021.42057 PMC 바로가기 [Article Type] Controlled Clinical Trial
Surveillance of SARS-CoV-2 antibodies of patients in the local affected area during Wuhan lockdownWuhan Lockdown 동안 국소 영향을받는 지역에서 환자의 SARS-COV-2 항체 감시Research Article Published on 2022-01-042022-09-01 Journal: BMC Infectious Diseases [Category] SARS, 진단, 치료기술, 치료법, [키워드] affected age All participants clinic Clinical sign Clinical signs Comorbidity convalescent patient Convalescent patients COVID-19 COVID-19 outbreak COVID-19 pandemic fragment of gold herd immunity highest Humoral immunity IgG IgM IgM and IgG Immunity indicated individual individuals information Local lockdown medical staff men natural reservoir no significant difference nucleic acid nucleocapsid outbreak Outpatient participant Patient positive rate positive rates Prevalence prevalence rate provide qualitative test Result SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 IgM SARS-CoV-2 infections sensitivity Seroprevalence Serosurveillance significant difference significantly higher specificity Spike protein syndrome the mean the SARS-CoV-2 Vaccination strategy Vaccine virus was measured were measured women Wuhan [DOI] 10.1186/s12879-021-07010-w PMC 바로가기 [Article Type] Research Article
T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre prospective cohort study이전에 감염된 SARS-CoV-2-naive 영국 의료 종사자의 첫 BNT162b2 백신 투여에 대한 T 세포 및 항체 반응: 다기관 전향적 코호트 연구Multicenter Study Published on 2022-01-012022-09-10 Journal: The Lancet. Microbe [Category] MERS, SARS, 변종, 진단, 치료법, [키워드] Affect All participants Analysis anti-SARS-CoV-2 antibodies antibody Antibody Response antibody unit Antibody Units applied benefit blood sample Blood samples BNT162b2 BNT162b2 vaccine collected coronavirus cryopreserved PBMCs Department determine determined by dose doses enrolled enzyme-linked immunospot assay exclusion criteria finding first dose fresh peripheral blood mononuclear cells funding Future greater health-care hospital IgG antibodies IgG antibody immune response immune responses individual individuals infected individual Infection infection with SARS-CoV-2 interferon interferon-γ IQR magnitude median median time mononuclear cell mononuclear cells mRNA vaccine multicentre naïve individuals nucleocapsid Older Oxford participant PBMCs Peripheral blood Peripheral blood mononuclear cells Pfizer–BioNTech positive prospective cohort study quantified receiving response RT-PCR SARS-COV-2 infection SARS-CoV-2 vaccine second dose single dose specific IgG antibodies Specific T-cell response spike-specific IgG spike-specific IgG antibodies spike-specific T-cell response spot spot-forming unit spot-forming units T-cell T-cell Response T-cell responses the median the SARS-CoV-2 vaccination Vaccine vaccine dose vaccine doses variants variants of concern was determined [DOI] 10.1016/S2666-5247(21)00275-5 PMC 바로가기 [Article Type] Multicenter Study