Drr4covid: Learning Automated COVID-19 Infection Segmentation From Digitally Reconstructed RadiographsComputers and Information Processing Published on 2020-11-162022-10-30 Journal: Ieee Access [Category] COVID-19, [키워드] annotation approach automated COVID-19 COVID-19 diagnosis COVID-19 infection COVID-19~diagnosis CXR deep learning Detection limit domain DRRS experiment faster heterogeneity IMPROVE indicated Infection Infection Segmentation learning lung positive quantification Radiograph radiological reconstructed Region Segmentation significantly statistical analysis Volume X-ray X-ray imaging [DOI] 10.1109/ACCESS.2020.3038279 PMC 바로가기 [Article Type] Computers and Information Processing
Analyzing inter-reader variability affecting deep ensemble learning for COVID-19 detection in chest radiographsResearch Article Published on 2020-11-122022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] affecting Algorithm annotation approach benefit Characteristics Chest chest X-ray CNNs Coronavirus disease 2019 COVID-19 CXR deep learning disease estimation help highlight IMPROVE knowledge Level limitation parameter performance random region of interest ROI several limitations Simultaneous Stage statistical analysis Support truth Variability [DOI] 10.1371/journal.pone.0242301 PMC 바로가기 [Article Type] Research Article
Genomic diversity and evolution, diagnosis, prevention, and therapeutics of the pandemic COVID-19 diseaseGenomics Published on 2020-09-012022-10-28 Journal: PeerJ [Category] COVID-19, [키워드] acquisition acute respiratory syndrome Amino acid Analysis annotation Antigen available data candidate candidate drugs caused cleavage site Comprehensive coronavirus coronavirus disease COVID-19 COVID-19 disease COVID-19 patients Deletion diagnose Diagnosis diagnostic diagnostics effective Evolution functional furin genetic diversity Genome evolution genomic glycoprotein insertion knowledge Laboratory management mutations nucleotides pandemic pathogenic polybasic predicted real-time RT-PCR released Research RNA virus SARS-CoV-2 SARS-CoV-2 genome shown Substitution Surveillance therapeutic therapeutic agent Therapeutics therapy Trial trials Vaccine Vaccines viral infection virus whole-genome Wuhan, China zoonotic [DOI] 10.7717/peerj.9689 PMC 바로가기 [Article Type] Genomics
Genome-wide analysis of SARS-CoV-2 virus strains circulating worldwide implicates heterogeneityArticle Published on 2020-08-192022-10-04 Journal: Scientific Reports [Category] MERS, 변종, 유전자 메커니즘, [키워드] ACE2 acute respiratory syndrome Amino acid Analysis analyzed angiotensin-converting enzyme 2 annotation arginine Asia Belgium Case fatality rate circulating coding sequence Complete Computational biology and bioinformatics conserved Coronavirus-2 COVID-19 pandemic Deletion domain effective England epidemiological data epitope Europe European Evolution Frame France Frequency genetic variants genetics Genome genome sequence genomic GISAID database globe heterogeneous implication Interaction Italy lysine Microbiology Mutation Netherlands neutralizing antibody North America nucleotide ORF10 ORF1ab ORF7a pandemic polyprotein Prophylaxis Protein Proteins RBD remained reported residue responsible RNA virus SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 strain SARS-CoV-2 virus strain sequence Shanghai Spain Substitution the SARS-CoV-2 genome Variation Viral protein virus strains [DOI] 10.1038/s41598-020-70812-6 PMC 바로가기 [Article Type] Article
VADR: validation and annotation of virus sequence submissions to GenBankSoftware Published on 2020-05-242022-10-27 Journal: BMC Bioinformatics [Category] Coronavirus, Fulltext, MERS, [키워드] added alignment Analysis annotation annotations automatically Biotechnology center Characteristics checked curated Dengue GenBank hidden markov model identify IMPROVE incrementally Influenza virus Intervention Local mapped NCBI ncRNA Norovirus nucleotide nucleotide sequence Other Protein RefSeq researcher Result SARS-CoV-2 sequence sequence submission viral sequence viral sequences virus [DOI] 10.1186/s12859-020-3537-3 PMC 바로가기 [Article Type] Software
High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosaArticle Published on 2020-02-242022-10-29 Journal: International Journal of Oral Science [Category] COVID-19, SARS, [키워드] 2019-nCoV ACE2 ACE2 receptor analyzed annotation Atla Biomarkers CAP Cell Clinical practice collected database dataset demonstrated Diseases epithelial cell Evidence explained expressed expression Final high risk host cell receptor identify independent Infection mechanism mucosa oral mucosa organ profile proportion provided receptor reported RNA-Seq single-cell transcriptome susceptibility tissue tongue virus were used [DOI] 10.1038/s41368-020-0074-x PMC 바로가기 [Article Type] Article
Pathosphere.org: pathogen detection and characterization through a web-based, open source informatics platformSoftware Published on 2015-12-292022-10-27 Journal: BMC Bioinformatics [Category] Coronavirus, [키워드] addition Analysis analyzed annotation bioinformatics Biological center Chemical Community complex coronavirus creating detect Government homology Host identify Illumina Infectious disease Ion iterative NCBI Next-generation sequencing NGS pathogen pathogen detection platform provide Result sequence sequenced Sequencing supplementary material Support tested the United State utility variety zoonotic [DOI] 10.1186/s12859-015-0840-5 PMC 바로가기 [Article Type] Software
The Human Phenotype Ontology: Semantic Unification of Common and Rare Disease인간 표현형 온톨로지: 일반 및 희귀 질병의 의미적 통합Article Published on 2015-07-022022-08-07 Journal: American Journal of Human Genetics [Category] 유전자 메커니즘, [키워드] alleles annotation annotations can be used common common disease common diseases comparable resource concept-recognition procedure diagnostics disease Disease model disease models FIVE frequencies Frequency genomic location HPO annotations Human human disease iterative procedure Mendelian disease Mendelian diseases next-generation sequence-variation data phenotype-driven analysis phenotypic annotation phenotypic overlap Precision precision and recall PubMed abstract rare disease community recall Research risk translational Translational research Unification [DOI] 10.1016/j.ajhg.2015.05.020 PMC 바로가기 [Article Type] Article
Streptococcus pneumoniae Genome Database (SPGDB): A database for strain specific comparative analysis of Streptococcus pneumoniae genes and proteins폐렴구균 유전체 데이터베이스 (SPGDB): 폐렴구균 유전자 및 단백질의 균주 특이적 비교 분석을 위한 데이터베이스journal-article Published on 2014-12-012024-08-04 Journal: Genomics [Category] 폐렴구균 감염증, [키워드] annotation database Genome pneumococci resistance [DOI] 10.1016/j.ygeno.2014.09.012 [Article Type] journal-article
Analysis of the Genome and Transcriptome of Cryptococcus neoformans var. grubii Reveals Complex RNA Expression and Microevolution Leading to Virulence AttenuationCryptococcus neoformans var.의 게놈 및 전사체 분석 grubii, 복잡한 RNA 발현 및 독성 약화로 이어지는 소진화를 밝혀냄Research Article Published on 2014-04-172022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] a major addition alternative polyadenylation Analysis analyzed annotation attenuation automated C. neoforman CDS chromosomal coding coding DNA sequence coding DNA sequences Comparative analysis Cryptococcus Cryptococcus neoforman Cryptococcus neoformans death Efficiency examination expressed gene expressed genes feature fungi Gene Expression Genes Genetic genetics Genome genome sequence genomic studies genomic study human pathogen identify Immunocompromised Immunocompromised patients in vitro culturing indicate intron introns involved isolate isolates Laboratory leading manual curation meningoencephalitis microevolution microevolutionary miscRNA miscRNAs molecular motif Mutation Non-coding RNAs occur opportunistic pathogen pathogen pathogenic performed phenotypic phenotypic and genome re-sequencing analysis polyadenylation site polyadenylation sites provide Region Regulation Replication representing responses responsible resulting RNA RNA-Seq-based analysis sequence sequenced sequences Sequencing serotype Spectrum strain Stress stress responses Transcription Transcriptome untranslated regions UTRs VAR variant variety virulence yeast [DOI] 10.1371/journal.pgen.1004261 PMC 바로가기 [Article Type] Research Article