Persistence of immunity and impact of third dose of inactivated COVID-19 vaccine against emerging variants면역의 지속성과 새로운 변이체에 대한 비활성화된 COVID-19 백신 3차 접종의 영향Clinical Trial Published on 2022-07-142022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단, 치료기술, 치료법, [키워드] (alpha Alpha Antibody titers B cell memory Beta booster booster dose Breakthrough infection breakthrough infections Cell mediated immunity clinical concern Controlled trial COVID-19 COVID-19 vaccine COVID-19 vaccines D614G Delta dose double-blind Effectiveness Heterologous homologous humoral humoral and cell mediated immunity Immunity immunogenicity inactivated India injection injection site itching magnitude neutralization titer Neutralizing antibodies neutralizing antibody omicron Pain persistence Phase 2 question Randomized controlled trial recipient redness registry responses Safe Serious Adverse Event Serious Adverse Events slight increase strain Trial registration vaccination variant variants VOCs within 6 months [DOI] 10.1038/s41598-022-16097-3 PMC 바로가기 [Article Type] Clinical Trial
The magnitude and timing of recalled immunity after breakthrough infection is shaped by SARS-CoV-2 variantsSARS-CoV-2 변종에 의해 형성되는 돌발성 감염 후 면역 회수의 규모와 시기Article Published on 2022-07-122022-09-11 Journal: Immunity [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] Activation antibody Antibody titers B cell B cell immunity B cells Breakthrough infection breakthrough infections CD4 CD4 T cell immunity CD8 CD8 T cell immunity cellular immunity Clinical outcome clinical outcomes COVID-19 COVID-19 vaccines Delta humoral immune Immunity Immunological memory IMPROVE increase in infecting Infection lack magnitude Neutralizing Neutralizing antibodies neutralizing antibody titers omicron phenotypic potential mechanism PROTECT protective effect Protective effects provide recall recalled response robust SARS-CoV-2 SARS-CoV-2 variant seropositive individual seropositive individuals severe COVID-19 T cell the timing vaccinated individuals vaccination variant Viral viral clearance viral replication while [DOI] 10.1016/j.immuni.2022.05.018 PMC 바로가기 [Article Type] Article
Clinical characteristics and immune profile alterations in vaccinated individuals with breakthrough Delta SARS-CoV-2 infectionsDelta SARS-CoV-2 감염이 있는 백신을 접종한 개인의 임상 특성 및 면역 프로필 변경Article Published on 2022-07-092022-09-11 Journal: Nature Communications [Category] COVID19(2023년), SARS, 바이오마커, 변종, 임상, 치료기술, [키워드] absorbance accelerated alteration Breakthrough infection breakthrough infections Characteristics clinical clinical recovery comparable Course cytokine Cytokine storms Delta delta variant facilitate groups Guangzhou Immune profile immunization Inactivated vaccine Inactivated Vaccines Inflammation Local median mononuclear cell observé outbreak PBMCs Peripheral blood Peripheral blood mononuclear cells Pneumonia protective effect Protective effects reduce reduced reported SARS-COV-2 infection significantly the disease transcription profile Transmission unique vaccinated individual vaccinated individuals vaccination Vaccine vaccine group Viral pneumonia viral RNA clearance viral titer VoC [DOI] 10.1038/s41467-022-31693-7 PMC 바로가기 [Article Type] Article
Antibody escape of SARS-CoV-2 Omicron BA.4 and BA.5 from vaccine and BA.1 serum백신 및 BA.1 혈청에서 SARS-CoV-2 Omicron BA.4 및 BA.5의 항체 탈출Article Published on 2022-07-072022-09-11 Journal: Cell [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] antibody antibody escape AstraZeneca BA.4 BA.5 breakthrough infections COVID-19 described dominant dose driving immune Immune Serum individual infections initial Lineage monoclonal antibodies Mutation neutralization omicron Pfizer raising recent Receptor-binding domain reduced reductions in replaced REPLACED BY SARS-CoV-2 Sequencing serum significant reductions South Africa spikes Spread the receptor-binding domain Vaccine vaccine breakthrough infections variant VoC [DOI] 10.1016/j.cell.2022.06.005 PMC 바로가기 [Article Type] Article
Neutralization capacity of antibodies elicited through homologous or heterologous infection or vaccination against SARS-CoV-2 VOCsSARS-CoV-2 VOCs에 대한 동종 또는 이종 감염 또는 백신 접종을 통해 유도된 항체의 중화 능력Article Published on 2022-07-042022-09-11 Journal: Nature Communications [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] Alpha antibody antigenic B.1 Beta Blood blood specimens Breakthrough infection breakthrough infections Clusters Combination Combined complex convalescent individual convalescent individuals Delta determined by elicited escape Gamma homologous homologous or heterologous Immune escape Immunity Infection isolates Last lead less neutralization Neutralization assay neutralization titer Neutralizing neutralizing capacity omicron Patient population immunity question raise SARS-CoV-2 SARS-CoV-2 isolate SARS-CoV-2 variant SARS-CoV-2 variants sera Seven specimen vaccinated individual vaccinated individuals vaccination Vaccinations variant variants VoC Zeta [DOI] 10.1038/s41467-022-31556-1 PMC 바로가기 [Article Type] Article
Spike Mutation Profiles Associated With SARS-CoV-2 Breakthrough Infections in Delta Emerging and Predominant Time Periods in British Columbia, Canada캐나다 브리티시 컬럼비아 주 델타의 신흥 및 우세 기간에 SARS-CoV-2 돌발 감염과 관련된 스파이크 돌연변이 프로필Article Published on 2022-07-042022-09-11 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] breakthrough infections Canada case-control study Community community setting contribute COVID-19 COVID-19 vaccination Delta domain dose effective epidemiological data estimates Evolution of SARS-CoV-2 fusion peptide genomic group identify individuals information less Logistic regression mechanism Mutation mutations N-terminal domain NTD pandemic penalized regression peptide Period population level Previous studies previous study profile public health measure RBD Receptor binding domain Region regions Relative risk Result risk S1/S2 cleavage SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 vaccine SARS-CoV-2 variant SARS-CoV-2 variants second vaccination Sequencing spike spike mutation spike mutations Spike protein stratified Surveillance thought time unique Vaccine Vaccine breakthrough vaccine breakthrough infection vaccine breakthrough infections vaccine escape Vaccine-induced immunity variant variants was used whole genome Whole genome sequencing [DOI] 10.3389/fpubh.2022.915363 PMC 바로가기 [Article Type] Article
Analyzing and Modeling the Spread of SARS-CoV-2 Omicron Lineages BA.1 and BA.2, France, September 2021-February 2022SARS-CoV-2 오미크론 계통 BA.1 및 BA.2의 확산 분석 및 모델링, 프랑스, 2021년 9월-2022년 2월Article Published on 2022-07-012022-09-11 Journal: Emerging Infectious Diseases [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed BA.1 BA.2 breakthrough infections coronavirus coronavirus disease COVID-19 Critical delta variant Epidemiology France generate Genomics growth advantage hospital Lineage magnitude Mass screening measure median modeling Mutation omicron Omicron variant PCR PCR cycle respiratory infections Result SARS-CoV-2 SARS-CoV-2 variant screening test screening tests severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 threshold value vaccine-preventable diseases variant variants virulence viruses Whole-genome sequence zoonoses [DOI] 10.3201/eid2807.220033 PMC 바로가기 [Article Type] Article
Adverse events and breakthrough infections associated with COVID-19 vaccination in the Indian population인도 인구에서 COVID-19 예방 접종과 관련된 부작용 및 획기적인 감염Article Published on 2022-07-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, [키워드] Administered Adverse adverse event adverse events adverse-events affected age analyzed approval Breakthrough infection breakthrough infections combating competency Complete concerning conducted consequence Council COVID-19 determine Effectiveness Ethical approval event Factor female females fraction Health higher risk ICMR Immunity inclusion criteria individual individuals Infection information Informed consent male Medical research Microsoft Excel Missing data morbidity Odds ratio Older age Participants Prevent provided questionnaire Research response Retrospective study SARS-CoV-2 SARS-COV-2 infection Stata statistical difference statistical differences status the vaccine vaccination Vaccine Variability variants of SARS-CoV-2 were excluded with COVID-19 [DOI] 10.1002/jmv.27708 PMC 바로가기 [Article Type] Article
Breakthrough Infections Following mRNA SARS-CoV-2 Vaccination in Kidney Transplant Recipients신장 이식 수혜자에서 mRNA SARS-CoV-2 백신 접종 후 획기적인 감염Article Published on 2022-07-012022-09-11 Journal: Transplantation [Category] COVID19(2023년), SARS, 변종, [키워드] 95% confidence interval administration age Analysis analyzed BNT162b2 BNT162b2 vaccine breakthrough infections clinical clinical effectiveness clinical picture collected confirmation coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 severity death died dose excluded General population hazard ratio hospitalized patients independent risk factor independent risk factors kidney transplant Mortality mRNA mRNA vaccine mRNA-1273 mRNA-1273 vaccine multivariable analysis Nephrology no difference no differences not improved outcome Patient Pneumonia receiving recipient registry remained Research SARS-CoV-2 significantly lower Society Spanish survival survival analysis These data Transplant vaccination Vaccination Status Vaccine vaccine doses variant with COVID-19 [DOI] 10.1097/TP.0000000000004119 PMC 바로가기 [Article Type] Article
A case report of breakthrough infection with the SARS-CoV-2 delta variant and household transmission: Role of vaccination, anti-spike IgG and neutralizing activitySARS-CoV-2 델타 변이형 돌발성 감염 및 가정전파 증례: 백신의 역할, 스파이크 방지 IgG 및 중화 활성Case Reports Published on 2022-07-012022-09-11 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Anti-spike anti-Spike IgG Antibody titers BNT162b2 BNT162b2 vaccine Breakthrough infection breakthrough infections Case report Clinical course clinical symptom contribute coronavirus defined Delta delta variant dose female Fever gradually increased healthcare worker IgG Immunoglobulin Immunoglobulin G index case individual individuals Infection Neutralizing activity Neutralizing antibodies neutralizing antibody occur patients remained respiratory role SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 neutralizing antibody secondary case severe acute respiratory syndrome Coronavirus the SARS-CoV-2 vaccinated individual vaccinated individuals vaccination Vaccine variant [DOI] 10.1016/j.jiac.2022.02.003 PMC 바로가기 [Article Type] Case Reports