Paper-Based Test for Rapid On-Site Screening of SARS-CoV-2 in Clinical Samples임상 샘플에서 SARS-COV-2의 빠른 현장 스크리닝을위한 종이 기반 테스트Article Published on 2021-11-302022-09-01 Journal: Biosensors [Category] 진단, 치료기술, [키워드] amplification buffer capture clinical clinical samples colorimetric detection Concentration COVID-19 pandemic detect detection Efficiency focus horseradish peroxidase HRP lateral flow lateral flow assay lateral flow strip magnetic focus enhancement nasal swab pathogen Pathogens PBS peroxidase probe Rapid Recognition recognize Saliva saliva samples Sample SARS-CoV-2 SARS-CoV-2 monitoring Screening sensitivity specificity Spread Test the SARS-CoV-2 virus particles was used [DOI] 10.3390/bios11120488 PMC 바로가기 [Article Type] Article
Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: The CAPTURE study암 환자에서 예방 접종 후 SARS-COV-2 변이체에 대한 적응 면역 및 중화 항체 : 캡처 연구Clinical Trial Published on 2021-11-232022-08-13 Journal: Nature cancer [Category] MERS, SARS, 바이오마커, 변종, 임상, 진단, 치료기술, 치료제, [키워드] Adaptive immunity Administered administration anti-CD20 anti-CD20 treatment Antibody Response Antibody titers AZD1222 BNT162b2 Cancer cancer patient Cancer patients cancers capture CAPTURE study comparable Concordance COVID-19 COVID-19 immunity COVID-19 pandemic detectable dose evaluated Hematological malignancies Hematological malignancy implication individuals without cancer malignancies malignancy management median nAb response NAb responses NAbT Neutralising Antibodies neutralizing antibody Neutralizing antibody titer of BNT162b2 Patient patients Patients with cancer patients with haematological proportion prospective cohort study Prospective Study reduced SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2 variants Seroconversion seroconversion rates solid cancer solid cancers T-cell Response T-cell responses undetectable vaccination Vaccine Vaccine-induced T-cell response Vaccine-induced T-cell responses Vaccines VOCs wildtype [DOI] 10.1038/s43018-021-00274-w PMC 바로가기 [Article Type] Clinical Trial
A common methodological phylogenomics framework for intra-patient heteroplasmies to infer SARS-CoV-2 sublineages and tumor clonesSARS-COV-2 Sublineages 및 종양 클론을 추론하는 환자 내 이종성을위한 일반적인 방법 론적 계통 발생 유전학 프레임 워크Research Published on 2021-11-162022-09-10 Journal: BMC Genomics [Category] MERS, SARS, 변종, 유전자 메커니즘, [키워드] Accuracy acquisition assumption Birth Cancer cancer patient capture clinically Clonal evolution clone clones co-infecting COVID-19 COVID-19 patient disease Evolution Frequency Genetic genetic material genomic genomic data genomic read genomic variant handle heterogeneity highlighting identify illness implication in viral Infection information methodological Mutation offer Phylogenetic Phylogenetic tree phylogenies Phylogenomics Phylogeny provide resistance mechanism resistance mechanisms Result SARS-CoV-2 SARS-CoV-2 virus supplementary material targets the mean the SARS-CoV-2 virus therapeutic therapy Treatment Tumor Tumor evolution undergo variant frequency Viral [DOI] 10.1186/s12864-021-07660-9 PMC 바로가기 [Article Type] Research
Evaluation of a bioaerosol sampler for indoor environmental surveillance of Severe Acute Respiratory Syndrome Coronavirus 2중증 급성 호흡기 증후군의 실내 환경 감시를위한 바이오 에로솔 샘플러 평가 코로나 바이러스 2Research Article Published on 2021-11-152022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 치료기술, 치료제, [키워드] ACh ACM acute respiratory syndrome coronavirus Administered aerosol capture Concentration contagious coronavirus coronavirus 2 effective eight experiments Genome greater highest hour impacted impaction increasingly individual investigated less life media nucleic acid respiratory risk room air SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spread Support Surveillance Swab utility Vaccine [DOI] 10.1371/journal.pone.0257689 PMC 바로가기 [Article Type] Research Article
Non-pharmaceutical interventions, vaccination, and the SARS-CoV-2 delta variant in England: a mathematical modelling study영국의 비약물적 개입, 백신 접종, SARS-CoV-2 델타 변종: 수학적 모델링 연구Articles Published on 2021-11-132022-09-10 Journal: Lancet (London, England) [Category] MERS, SARS, 변종, [키워드] Alpha B.1.617.2 Bayesian calibrated the model capture Commonwealth condition country Coverage COVID-19 credible interval CrI cross-protection cumulative deaths delta variant described development Effectiveness England English Epidemic estimate Evidence finding Foreign funding hospital Hospital admission Hospital admissions Infection Intervention investigated lifting lockdown lockdown restriction lockdown restrictions Mathematical modelling Measures Medical Research Council mixing natural immunity NPI NPIs office pandemic parameter PCR testing per day population immunity reduced resulting risk SARS-CoV-2 transmission sensitivity step surveillance data the epidemic the SARS-CoV-2 the timing timeline Trajectories trajectory Transmissibility Transmission vaccination Vaccine variant variant of SARS-CoV-2 variants was done Wellcome Trust [DOI] 10.1016/S0140-6736(21)02276-5 PMC 바로가기 [Article Type] Articles
Body Temperature Monitoring for Regular COVID-19 Prevention Based on Human Daily Activity Recognition인간의 일상 활동 인식을 기반으로 한 정기적인 COVID-19 예방을 위한 체온 모니터링Article Published on 2021-11-122022-09-10 Journal: Sensors (Basel, Switzerland) [Category] MERS, SARS, 치료기술, [키워드] absence Accuracy activities activity addition Algorithm Algorithms applied Body body surface temperature body temperature capture characteristic Classifier collected COVID-19 Daily dataset deep learning deviation distribution curve Epidemic evaluation metrics experimental results Fever forest Human human activity recognition (HAR) human behavior identify machine learning (ML) monitoring Normal distribution normalization participant Patient physical prevention Prevention and control provided random Random forest raw data Recognition Regular Sitting Standardization surface temperature temperature temperature sensor the epidemic the mean variance wearable sensors [DOI] 10.3390/s21227540 PMC 바로가기 [Article Type] Article
A Multifunctional Neutralizing Antibody‐Conjugated Nanoparticle Inhibits and Inactivates SARS‐CoV‐2다기능 중화 항체 - 접합 된 나노 입자는 SARS -COV -2를 억제하고 불 활성화시킨다Research Article Published on 2021-11-102022-09-01 Journal: Advanced Science [Category] MERS, SARS, 변종, 신약개발, 진단, [키워드] 2019 coronavirus disease acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition block capture captures caused coronavirus coronavirus disease COVID‐19 COVID‐19 curative described expected flexible generate global pandemic glycol heat host cell host cells in vitro in vivo inactivation Intensive irradiation multifunctional multifunctional nanoparticle nanoparticle Neutralizing Neutralizing antibodies neutralizing antibody outbreak photothermal therapy platform Polyethylene glycol Polymer Proteins provide pseudovirion Research respiratory SARS‐CoV‐2 SARS‐CoV‐2 antibodies SARS‐CoV‐2 antibody SARS‐CoV‐2 infection SARS‐CoV‐2 severe acute respiratory syndrome Coronavirus significantly therapeutic treat Treatment variants Viral viral infection virus virus inactivation viruses [DOI] 10.1002/advs.202103240 PMC 바로가기 [Article Type] Research Article
Antibody-Free Rapid Detection of SARS-CoV-2 Proteins Using Corona Phase Molecular Recognition to Accelerate Development Time개발 시간을 가속화하기 위해 코로나 단계 분자 인식을 사용하여 SARS-CoV-2 단백질의 항체 없는 신속한 검출Article Published on 2021-11-092022-09-11 Journal: Analytical Chemistry [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody approach biological activity capture carbon complex conditions Corona coronavirus detection develop development Device ethylene ETHYLENE GLYCOL faster fluorescence detection fluorescent glycol human saliva injection Instrumentation limit of detection molecular N and S proteins nucleocapsid Pandemics phase platform point-of-care Protein Rapid receptor Recognition recognize respiratory response S proteins SARS-CoV-2 SARS-CoV-2 protein SARS-CoV-2 proteins severe acute respiratory syndrome Coronavirus subunit time unique Viral Viral protein Viral proteins [DOI] 10.1021/acs.analchem.1c02889 PMC 바로가기 [Article Type] Article
Genomic diversity of SARS-CoV-2 in Oxford during United Kingdom’s first national lockdown영국 최초의 국가 폐쇄 기간 동안 옥스포드에서 SARS-COV-2의 게놈 다양성Article Published on 2021-11-022022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 변종, 유전자 메커니즘, 진단, 치료기술, 치료제, [키워드] Alter analyzed capture cause change changes in collected COVID-19 detect effort Epidemiology evade Evolution First wave Genome genomic helping host immune system in viral independent Infection infection rate infection rates interactions International isolate Local local spread lockdown Molecular epidemiology Mutation National occur outbreak Oxford pathogen Population screening Public health responses SARS-CoV-2 SARS-CoV-2 genome Sequencing Spread Surveillance the SARS-CoV-2 genome Travel United Kingdom utility Viral viral epidemics viral genomes viral strain viral strains virulence virus whole-genome sequencing [DOI] 10.1038/s41598-021-01022-x PMC 바로가기 [Article Type] Article
Prioritisation of Candidate Genes Underpinning COVID-19 Host Genetic Traits Based on High-Resolution 3D Chromosomal TopologyGenetics Published on 2021-10-252022-10-31 Journal: Frontiers in Genetics [Category] COVID-19, [키워드] 3D chromosomal architecture applied approach arising association authors Blood Brain candidate capture cells chromosomal COVID-19 COVID-19 pathology COVID-19 susceptibility disease DNA enhancers and promoters experiments expressed Genome-wide association study GWAS GWAS (genome-wide association studies) GWAS meta-analysis GWAS variant High-resolution Inflammatory response Interaction interactions involved lung carcinoma Pathways primary cell type putative target gene Region regions regulate Regulatory regulatory genome severity statistical tissues traits variant viral infection [DOI] 10.3389/fgene.2021.745672 PMC 바로가기 [Article Type] Genetics