Changes in dispensing of medicines proposed for re-purposing in the first year of the COVID-19 pandemic in AustraliaArticle Published on 2022-06-152022-10-04 Journal: PLoS ONE [Category] 신약개발, [키워드] 95%CI Analysis average change changes in Characteristics Colchicine Corticosteroid Corticosteroids COVID-19 COVID-19 pandemic cross-sectional Dispensing effective Evidence expected help Hydroxychloroquine increase increase in increases in Ivermectin limit media Medicine Medicines Other Pandemics Patient perceived benefit performed Practitioner Prevent quantified Regulatory sustained therapeutic understanding Vitamin D while [DOI] 10.1371/journal.pone.0269482 PMC 바로가기 [Article Type] Article
Severe Anemia Due to Cold Agglutinin Syndrome in a COVID-19 Patient with IgM Monoclonal Gammopathy of Undetermined Significance Successfully Treated with Corticosteroids코르티코스테로이드로 성공적으로 치료된 유의미한 IgM 단클론성 감마병증이 있는 COVID-19 환자의 한랭응집소 증후군으로 인한 중증 빈혈Case Reports Published on 2022-06-012022-09-12 Journal: Internal medicine (Tokyo, Japan) [Category] MERS, 진단, [키워드] Administered Agglutinin Anemia Asian Autoimmune autoimmune hemolytic anemia CAS Cold cold agglutinin syndrome Corticosteroid cough COVID-19 diagnosed with COVID-19 disorder Dyspnea effective gammopathy hemoglobin hemolytic anemia IgM Infection Japanese laboratory data lymphoid monoclonal monoclonal gammopathy of undetermined significance. novel coronavirus disease required secondary Significance Standard therapy syndrome therapy Undetermined [DOI] 10.2169/internalmedicine.8647-21 PMC 바로가기 [Article Type] Case Reports
Comparing the efficacy of tocilizumab with corticosteroid therapy in treating COVID-19 patients: a systematic review and meta-analysisCOVID-19 환자 치료에서 토실리주맙과 코르티코스테로이드 요법의 효능 비교: 체계적인 검토 및 메타 분석Review Published on 2022-06-012022-09-12 Journal: Daru : journal of Faculty of Pharmacy, Tehran Univ [Category] COVID19(2023년), SARS, 진단, [키워드] 95%CI baseline characteristics Case-control case-control studies case-control study Combination contributed Corticosteroid corticosteroid therapy COVID-19 database determinant Dexamethasone did not reduce dose regimen drug Drug efficacy Efficacy Factor High dose identify IMPROVE mechanical ventilation Meta-analysis Methylprednisolone Mortality outcome Patient patients pulse Randomized Randomized controlled trial randomized trials RCT RCTs reduce reducing mortality reduction searched severe COVID-19 patients shown significantly systematic review therapeutic therapy Tocilizumab treating COVID-19 was performed [DOI] 10.1007/s40199-021-00430-8 PMC 바로가기 [Article Type] Review
Posterior reversible encephalopathy syndrome – A pathology that should not be overlooked in the era of COVID-19후두 가역성 뇌병증 증후군 - 코로나19 시대에 간과해서는 안 될 병리학Case Reports Published on 2022-06-012022-09-11 Journal: The American journal of emergency medicine [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Antibiotics Aphasia Autoimmune diseases blindness Case report cause Computed tomography coronavirus coronavirus disease Coronavirus disease 2019 cortical cortical blindness Corticosteroid Corticosteroids cough COVID-19 delta variant Department described determine diagnosed with COVID-19 Diagnosis dominant drugs Dyspnea eclampsia Emergency emergency department Encephalopathy Europe exhibiting exposure to Fever full recovery general practitioner generalized tonic-clonic seizures had no hypertensive Immediate Infectious disease Infectious diseases Invasion knowledge lobes material medical history MRI nervous system neurological Neurological complication Neurological complications Neurological symptom Neurological symptoms occipital Organ failure outcome pathology Patient patients with COVID-19 Pneumonia Posterior Posterior reversible encephalopathy syndrome PRES presenting radiological receiving renal resolved SARS-CoV-2 SARS-CoV-2 pneumonia secondary to Seizures Sepsis severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe SARS Shortness of breath Symptom syndrome Thoracic Treatment variant [DOI] 10.1016/j.ajem.2022.03.005 PMC 바로가기 [Article Type] Case Reports
Persistent viral RNA shedding of SARS-CoV-2 is associated with delirium incidence and six-month mortality in hospitalized COVID-19 patientsSARS-CoV-2의 지속적인 바이러스 RNA 방출은 입원한 COVID-19 환자의 섬망 발병률 및 6개월 사망률과 관련이 있습니다Article Published on 2022-06-012022-09-12 Journal: GeroScience [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] 95% CI age BMI Chronic kidney disease Corticosteroid COVID-19 COVID-19 hospitalization delirium Diabetes Mellitus diagnosis of COVID-19 dysfunction Factor hospitalized COVID-19 patient hospitalized COVID-19 patients hospitalized patient implication In-hospital incidence increasingly initial Logistic regression Male sex Medicine Mortality occur Occurrence outcome Patient persistent positive predictor remained SARS-CoV-2 SARS-CoV-2 RT-PCR severity shedding significantly Viral RNA shedding viral shedding [DOI] 10.1007/s11357-022-00561-z PMC 바로가기 [Article Type] Article
Early Th2 inflammation in the upper respiratory mucosa as a predictor of severe COVID-19 and modulation by early treatment with inhaled corticosteroids: a mechanistic analysis중증 COVID-19의 예측인자로서 상부 호흡기 점막의 초기 Th2 염증 및 흡입 코르티코스테로이드 조기 치료에 의한 조절: 기계론적 분석Clinical Trial Published on 2022-06-012022-09-11 Journal: The Lancet. Respiratory Medicine [Category] COVID19(2023년), SARS, 바이오마커, 신약개발, 임상, 치료법, 치료제, [키워드] 1:1 adaptive airway Analysis Anti-viral antipyretics assigned AstraZeneca Biomarker Blood blood sample Blood samples Budesonide CCL17 chemokine clinical benefit clinical symptom clinical trial clinically Cohort collected Concentration Corticosteroid Course COVID-19 COVID-19 disease COVID-19 disease course Data collection decrease deteriorate dose early treatment Efficacy elevated enzyme eosinophil epithelial epithelial lining Evolution experimental analysis healthy controls healthy individuals IL-33 immunoassay individual Inflammation Inflammatory Inflammatory mediators Inflammatory response Inhaled inhaled budesonide inhaled corticosteroid initial interferon interferon response interleukin Intervention investigated Ligand marker mechanism Meso Scale Discovery modulated modulation mucosa mucosal nasal Nasal sample nasal samples Necrosis negative control nose Observational data open label outcomes over Oxford parallel group participant Patient patients with SARS-CoV-2 Phase 2 Primary outcome Proteins randomisation randomised Randomly receive recruited reducing Registered respiratory tract SARS-COV-2 infection severe COVID-19 severe COVID-19 disease shown systemic inflammation T-cell Response Th2 the SARS-CoV-2 Treatment Trial tumour necrosis factor tumour necrosis factor-α twice a day University of Oxford upper respiratory usual care usual care group was collected were assessed were used Whole blood with COVID-19 [DOI] 10.1016/S2213-2600(22)00002-9 PMC 바로가기 [Article Type] Clinical Trial
Severe disease exacerbation after mRNA COVID-19 vaccination unmasks suspected multiple sclerosis as neuromyelitis optica spectrum disorder: a case reportmRNA COVID-19 백신 접종 후 심각한 질병 악화로 의심되는 다발성 경화증이 시신경척수염 스펙트럼 장애로 밝혀짐: 사례 보고Case Reports Published on 2022-05-182022-09-12 Journal: BMC Neurology [Category] MERS, 진단, [키워드] AQP4 association bladder bowel Case report Central nervous system CNS CNS disorder contribute Corticosteroid COVID-19 COVID-19 pandemic COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines CSF detection diagnosed Diagnosis disease disorder immunization Inflammatory intravenous knowledge management mechanism mRNA MS multiple sclerosis Neurological disorder NMOSD Occurrence Patient Pfizer-BioNTech positive reported serum suffered Symptoms the patient vaccination Vaccines Viral vector [DOI] 10.1186/s12883-022-02698-y PMC 바로가기 [Article Type] Case Reports
RAGE has potential pathogenetic and prognostic value in nonintubated hospitalized patients with COVID-19RAGE는 삽관되지 않은 COVID-19 입원 환자에서 잠재적인 병리학적 및 예후적 가치가 있습니다.Clinical Trial Published on 2022-05-092022-09-11 Journal: JCI Insight [Category] MERS, 바이오마커, 임상, 진단, 치료법, [키워드] adjusted age Antibody Response Antigen association bamlanivimab baseline Biomarker Biomarkers BMI clinical Clinical outcome clinical outcomes Clinical practice clinical trial Concentration correlated correlation Corticosteroid corticosteroid treatment COVID-19 Cox regression CRP Cytokines diabetes Diabetes Mellitus enrolled Factor highest Hospitalized hospitalized patient hospitalized patients IL-6 Illness severity Indicator likelihood mechanically ventilated nucleocapsid antigen oxygen participant Participants patients with COVID-19 plasma positive Prognostic value Pulmonology quartile RAGE rate ratio receptor renal impairment risk of death Sex significantly lower Spearman supplemental oxygen sustained systemic inflammation tested Trial Viral viral burden Viral load was measured was used were used with COVID-19 [DOI] 10.1172/jci.insight.157499 PMC 바로가기 [Article Type] Clinical Trial
Factors associated with hospital admission and adverse outcome for COVID-19: Role of social factors and medical careResearch article Published on 2022-05-012022-10-05 Journal: Infectious diseases now [Category] COVID19(2023년), SARS, 바이오마커, [키워드] acute kidney failure Admission adverse outcome adverse outcomes age analyses association being Care chest CT scan Comorbidities Corticosteroid Corticosteroids COVID-19 CRP level death Deprivation Desaturation Diabetic disorder Factor Follow-up form France General population Geographical origin hospital Hospital admission Hospitalization Hospitalized Hydrocortisone independent risk factor laboratory-confirmed lesion Logistic male mechanical ventilation morbidity and mortality Neuropsychiatric obese Occurrence Older outcomes patients patients hospitalized Protective reduced Result risk role Sex Socioeconomic deprivation Socioeconomic Factors Treatment were used [DOI] 10.1016/j.idnow.2022.02.001 [Article Type] Research article
Effectiveness of Systemic Corticosteroids Therapy for Nonsevere Patients With COVID-19: A Multicenter, Retrospective, Longitudinal Cohort StudyResearch article Published on 2022-05-012022-10-05 Journal: Value in health : the journal of the International [Category] COVID19(2023년), SARS, 치료제, [키워드] 95% confidence interval adjusted hazard ratio all-cause mortality Analysis association clinical evidence clinical outcomes clinically Cohort conducted Corticosteroid Corticosteroids COVID-19 Cox model Disease progression dose Efficacy elevated evaluate the effect Follow-up Hospitalization longitudinal Mortality multicenter Multiple linear regression objective outcomes Patient patients with COVID-19 Probability progression propensity score analysis propensity score matching Result retrospective cohort study risk SCU significantly systemic systemic corticosteroid systemic corticosteroids Treatment were used [DOI] 10.1016/j.jval.2021.12.013 [Article Type] Research article