Advances on Antiviral Activity of Morus spp. Plant Extracts: Human Coronavirus and Virus-Related Respiratory Tract Infections in the SpotlightArticle Published on 2020-04-182022-10-30 Journal: Molecules [Category] COVID-19, [키워드] Morus spp. absence activity advance Analysis analyzed antiviral activities antiviral activity antiviral property Antiviral strategies coronavirus CPE crude extract cytopathogenic effect disease effective Epidemic evaluated exhibited HCoV 229E HCoV-229E hosts Human human coronavirus life-threatening Morus Alba offer Outbreaks picornavirus picornaviruses plant Poliovirus reduced representing respiratory respiratory infection respiratory viruses responsible specific treatment Therapies tract VAR viral infections viral pathogens viral titer [DOI] 10.3390/molecules25081876 PMC 바로가기 [Article Type] Article
Antiviral Action of Tryptanthrin Isolated from Strobilanthes cusia Leaf against Human Coronavirus NL63Article Published on 2020-02-272022-10-28 Journal: Biomolecules [Category] Coronavirus, [키워드] Strobilanthes cusia Action Antiviral antiviral action antiviral activity biological activities cells children Chinese component components coronavirus CPE Cytopathic effect exhibited HCoV-NL63 Human human coronavirus human coronavirus NL63 immunocompromised individuals independent indicated indigodole B Infection inhibited investigated Isolated late stage leaf methanol NL63 Papain-like protease prevented progeny reducing Replication Respiratory virus infections Strobilanthe Treatment tryptanthrin viral RNA genome virucidal virus virus production [DOI] 10.3390/biom10030366 PMC 바로가기 [Article Type] Article
In silico design of a novel chimeric shigella IpaB fused to C terminal of clostridium perfringens enterotoxin as a vaccine candidate신규 키메라 시겔라 IpaB를 클로스트리디움 퍼프린젠스 엔테로톡신의 C 말단에 융합한 백신 후보의 인 실리코 설계Article Published on 2018-01-012024-08-22 Journal: Bioengineered [Category] 세균성이질, [키워드] Chimeric protein CPE IpaB Shigella vaccine candidate
Infectious Bronchitis Virus Infection Induces Apoptosis during Replication in Chicken Macrophage HD11 CellsArticle Published on 2017-07-262022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] Activation Ammonium Analysis Apoptosis apoptosis induction apoptotic blocked bronchitis caspase Caspases caused Cell cells cellular chicken chicken macrophage chloride CPE Cytopathic effect Efficacy expression extrinsic pathway flow cytometry IBV IBV infection Immune cell immune cells Infection Infectious Bronchitis Virus inhibited inhibitory intrinsic Macrophage macrophage cell line mammalian cell mechanism morphological changes offer previous study primary cells Replication reported Research suggested viability virus replication was increased [DOI] 10.3390/v9080198 PMC 바로가기 [Article Type] Article
In vitro antiviral effects and 3D QSAR study of resveratrol derivatives as potent inhibitors of influenza H1N1 neuraminidaseArticle Published on 2015-04-012023-06-24 Journal: Chemical biology & drug design [Category] 신종인플루엔자, [키워드] CoMFA CoMSIA CPE docking NA RV (3, 5, 4′-trihydroxy-trans-stilbene) derivatives [DOI] 10.1111/cbdd.12425
Recombinant duck enteritis virus expressing the HA gene from goose H5 subtype avian influenza virusArticle Published on 2013-12-052023-06-02 Journal: Vaccine [Category] 조류인플루엔자, [키워드] CEF chicken embryo fibroblast CPE cytopathic effects DEF DEV duck embryo fibroblast duck enteritis virus Duck enteritis virus (DEV) gE gEBn gEBw GI glycoprotein E glycoprotein I Goose origin H5N1 avian influenza virus (AIV) HA hemagglutinin Hemagglutinin (HA) Highly pathogenic avian influenza virus HPAIV Post-vaccination pv rDEV recombinant DEV the extracellular region of gE gene the intracellular region of gE gene unique short US wild type DEV wtDEV. [DOI] 10.1016/j.vaccine.2013.10.035
Anti-influenza A virus activity of uridine derivatives of 2-deoxy sugarsArticle Published on 2013-10-012023-06-24 Journal: Antiviral Research [Category] 신종인플루엔자, [키워드] CC(50) classical swine fever virus concentration of the compound required to reduce cell viability by 50% concentration of the compound required to reduce virus plaque formation by 50% CPE CSFV CT cycle threshold Cytopathic effect Endoplasmic reticulum ER Glycoproteins Glycosylation inhibition HA hemagglutinin IC(50) influenza A virus l-1-tosylamide-2-phenylethyl chloromethyl ketone Madin–Darby canine kidney cells MDCK MOI multiplicity of infection NA neuraminidase S.D. selectivity index Sf9 SI Spodoptera frugiperda insect cell line standard deviations. TPCK Tunicamycin derivatives [DOI] 10.1016/j.antiviral.2013.07.014
Isolation and molecular characterization of type I and type II feline coronavirus in MalaysiaShort Report Published on 2012-11-212022-10-28 Journal: Virology Journal [Category] Coronavirus, MERS, [키워드] Antigen Asia cats Cell Cell culture characterized circulating clinical sample compared coronavirus CPE CrFK Cytopathic effect determined differentiation East Europe FCoV Fcwf-4 Feline infectious peritonitis finding FIPV indicated Infected inoculation isolate Isolation kidney Local Malaysia molecular Pathogenesis Phylogenetic phylogenetics positive prevalent reported RT-PCR RT-PCR assay S-gene sequence homology serological evidence similarity South syncytial cell tissue tropism type I USA virus virus isolation while [DOI] 10.1186/1743-422X-9-278 PMC 바로가기 [Article Type] Short Report
Quercetin 7-rhamnoside reduces porcine epidemic diarrhea virus replication via independent pathway of viral induced reactive oxygen speciesResearch Published on 2011-10-042022-10-28 Journal: Virology Journal [Category] Coronavirus, MERS, [키워드] addition antioxidant antiviral activity Course CPE Cytopathic effect DNA fragment DNA fragmentation Effect epidemic diarrhea flow cytometry Hypothesis inactive independent induce Infection investigated NAC pathway PEDV Production quercetin reactive oxygen specy reduce reduced reduction Result ROS Vero Cell virus replication [DOI] 10.1186/1743-422X-8-460 PMC 바로가기 [Article Type] Research