Salmonella Pathogenicity Island 1 (SPI-1) and Its Complex Regulatory Network살모넬라 병원성 섬 1 (SPI-1) 및 그 복잡한 조절 네트워크Article Published on 2019-07-312024-07-29 Journal: Frontiers in Cellular and Infection Microbiology [Category] 살모넬라증, [키워드] effector immune response Regulation Salmonella SPI-1 T3SS [DOI] 10.3389/fcimb.2019.00270 PMC 바로가기
Kctd9 Deficiency Impairs Natural Killer Cell Development and Effector FunctionImmunology Published on 2019-04-102022-11-01 Journal: Frontiers in Immunology [Category] Coronavirus, MERS, [키워드] ameliorated caused CD11b Cell cytokine cytotoxicity deficiency degranulation development domain effector evidenced exhibited expressed expression fulminant hepatitis function granzyme B Hepatitis hepatitis B homologous identify IFN-γ Immune-mediated in vitro Infection investigated Kctd9 knockout mice Lineage liver Liver damage manifested maturation mechanism mice murine hepatitis virus natural natural killer NK cell NK cell function NK cells Patient phenotype potassium channel progression proliferative proportion reduction in Regulation selective supported survival transcription factors tumor cell wild-type [DOI] 10.3389/fimmu.2019.00744 PMC 바로가기 [Article Type] Immunology
The nuclear hormone receptor NHR-86 controls anti-pathogen responses in C . elegans핵 호르몬 수용체 NHR-86은 C에서 항병원체 반응을 조절한다. 엘레강스Research Article Published on 2019-01-222022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] activate Activation adaptive Analysis Author bacterial pathogen baseline bind biological function canonical characterized chromatin chromatin immunoprecipitation Control determine Drosophila effector elegan elegans exogenous ligands experiments family function Genetic genetic screen Genome homolog hormone receptor hormone receptors host response Human immune immune activation immunostimulatory induce Infection innate immune activation majority MAPK modulate nuclear pathogen pathway PMK-1 positioned promoter promoters Protective Protein provide Pseudomonas aeruginosa Recognition Regulation required response small molecule target Transcription transcription factor transcription factors transcriptional transcriptional regulator transcriptional response Transcriptome [DOI] 10.1371/journal.pgen.1007935 PMC 바로가기 [Article Type] Research Article
Tracking elusive cargo: Illuminating spatio‐temporal Type 3 effector protein dynamics using reporters추적하기 어려운 화물: 리포터를 사용하여 시공간적 3형 효과 단백질 역학을 밝히기Article Published on 2017-11-232024-08-21 Journal: Cellular Microbiology [Category] 세균성이질, [키워드] effector Localisation Methods Protein reporter secretion [DOI] 10.1111/cmi.12797 PMC 바로가기
Glucosamine stimulates pheromone-independent dimorphic transition in Cryptococcus neoformans by promoting Crz1 nuclear translocation글루코사민은 Crz1 핵 전위를 촉진하여 Cryptococcus neoformans에서 페로몬 독립적인 이형 전이를 자극합니다Research Article Published on 2017-09-122022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Affect Antifungal antifungal therapy attenuate calcineurin caused Cell cellular response clinically complex component Cryptococcal cells cryptococcal meningitis cryptococcosis Cryptococcus Cryptococcus neoforman Cryptococcus neoformans cytoplasm demonstrated disease downstream effector effectors elicited fertile fungal Genetic genetic screen glucosamine glycerol Host Host immune response host immune responses hosts identity immune responses immune-stimulatory independent independent of Interaction isolate limitations majority mammalian MAPK Meningitis morphogenesis Morphological morphological change Morphotype nuclear translocation nucleus Pathogenesis pathway pheromone phosphatase promote promoted PROTECT raise recent reference strain responsible serotype shown signaling pathway stimulate stimulated strain Stress stress response subsequent suppressed switching transcription factor translocation Trigger undergo Vaccine Vaccine development virulence virulent yeast [DOI] 10.1371/journal.pgen.1006982 PMC 바로가기 [Article Type] Research Article
Salmonella SPI-2 Type III Secretion System Effectors: Molecular Mechanisms And Physiological Consequences살모넬라 SPI-2 제3형 분비 시스템 효과기: 분자 메커니즘과 생리학적 결과Article Published on 2017-08-092024-08-21 Journal: Cell Host & Microbe [Category] 살모넬라증, [키워드] bacterial pathogen effector pathogenicity island Salmonella SPI-2 type III secretion system virulence
Type III Secretion in the Melioidosis Pathogen Burkholderia pseudomallei멜리오이드증 병원체인 Burkholderia pseudomallei의 제3형 분비Review Published on 2017-06-152024-07-30 Journal: Frontiers in Cellular and Infection Microbiology [Category] 세균성이질, [키워드] Burkholderia pseudomallei effector melioidosis T3SS translocator [DOI] 10.3389/fcimb.2017.00255 PMC 바로가기 [Article Type] Review
Host Cell Nuclear Localization of Shigella flexneri Effector OspF Is Facilitated by SUMOylation시겔라 플렉스네리 효과기 OspF의 숙주 세포 핵 내 위치화는 SUMO화에 의해 촉진된다.Article Published on 2017-03-282024-08-22 Journal: Journal of Microbiology and Biotechnology [Category] 세균성이질, [키워드] effector nucelar localization. OspF Shigella flexneri SUMO
The Salmonella Effector SpvD Is a Cysteine Hydrolase with a Serovar-specific Polymorphism Influencing Catalytic Activity, Suppression of Immune Responses, and Bacterial Virulence *살모넬라 효과 인자 SpvD는 카탈리틱 활성, 면역 반응 억제 및 박테리아 병원성에 영향을 미치는 세로바 특이적 다형성을 가진 시스테인 하이드롤라제입니다.Article Published on 2016-12-092024-07-29 Journal: Brain stimulation [Category] 살모넬라증, [키워드] Bacterial pathogenesis crystal structure cysteine protease effector Salmonella enterica structure-function [DOI] 10.1074/jbc.M116.752782 PMC 바로가기
Transcription Factors Encoded on Core and Accessory Chromosomes of Fusarium oxysporum Induce Expression of Effector GenesFusarium oxysporum의 코어 및 액세서리 염색체에 인코딩된 전사 인자는 이펙터 유전자의 발현을 유도합니다Research Article Published on 2016-11-172022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Accessory accessory chromosome accessory chromosomes activate autonomous bind binding site chromatin chromatin condensation chromosome chromosomes colonisation connection conserved constitutive promoter core core genome determine DNA binding effector effectors ENCODE Evolution example expression extreme facilitate Factor FTF1 FTF2 fungal fungi Fusarium GC content Gene Expression Genes Genome genomic genomic region homolog homolog FTF2 homologous Host independent induce Infection Interaction investigated maintain motif motifs nine occurred oligonucleotide oligonucleotide arrays outcome overlapping pathogen Pathogenesis pathogenic pathogenicity Pathogens predicted promoters reference strain Region required RNAseq analysis secreted Sge1 specificity strain Strains tomato Transcription transcription factor transcription factor gene transcription factor genes transcription factors transcriptional transcriptionally transfer transferred transposon up-regulated virulence yeast [DOI] 10.1371/journal.pgen.1006401 PMC 바로가기 [Article Type] Research Article