Structural colour enhanced microfluidics Research Published on 2022-05-192022-10-05 Journal: Nature Communications [Category] 진단, [키워드] advance characterized demonstrated dependent on flexible independent intrinsic organized Polymer reduction shown [DOI] 10.1038/s41467-022-29956-4 [Article Type] Research
An Aptamer-Functionalised Schottky-Field Effect Transistor for the Detection of Proteins단백질 검출을 위한 압타머 기능 쇼트키 전계 효과 트랜지스터Article Published on 2022-05-182022-09-11 Journal: Biosensors [Category] COVID19(2023년), SARS, 치료기술, [키워드] Aptamers Biomarker Biomarkers biosensors changes in Concentration coronavirus disease Coronavirus disease 2019 COVID-19 detection determine disease Effect feasibility field effect transistors field-effect transistor flexible linear outbreak parameter SARS-CoV2 shown silicon Spike protein the disease the spike protein Thin film thin film sensors. transistor [DOI] 10.3390/bios12050347 PMC 바로가기 [Article Type] Article
Study protocol to test the efficacy of self-administration of dexmedetomidine sedative therapy on anxiety, delirium, and ventilator days in critically ill mechanically ventilated patients: an open-label randomized clinical trial중환자 기계 환기 환자의 불안, 섬망 및 인공 호흡기 일에 대한 덱스메데토미딘 진정 요법의 자가 투여 효과를 테스트하기 위한 연구 프로토콜: 공개 라벨 무작위 임상 시험Article Published on 2022-05-162022-09-11 Journal: Trials [Category] 임상, [키워드] addition aggregate alertness alleviate alteration Anxiety approach approaches assigned Care change clinical Clinical practice clinical trial Consistency Course COVID-19 case COVID-19 pandemic Critically ill delirium Depression dexmedetomidine distress Efficacy eligible Eligible participants eligible patient Eligible patients enrolment equipment extubation finding flexible functional Functional status healthcare ICU ICU care ICU patient ICU Patients identify impacted imperative intensive care intensive care unit life management Mechanical mechanical ventilation mechanical ventilatory support mechanically ventilated mechanically ventilated patient mechanically ventilated patients medication Open-label opioid outcome Oxygenation Pain Patient patient symptom Patient symptoms physical Post-traumatic stress disorder Protective protocol Psychological well-being Quality of life randomization Randomized randomized clinical trial Randomly receiving recruitment Secondary objective Secondary objectives Sedation sedative Self-management Side effects significantly study population subset Symptom therapy Trial trial enrolment usual care ventilator ventilator-free day Ventilator-free days ventilatory support [DOI] 10.1186/s13063-022-06391-w PMC 바로가기 [Article Type] Article
COVID-VU – ENT-UK national survey of flexible nasendoscopy in the upper aerodigestive tract amidst the COVID-19 pandemicObservational Study Published on 2022-05-092022-10-04 Journal: BMC health services research [Category] COVID19(2023년), SARS, 임상, [키워드] aerosol aerosol generating procedure AGP airway assessment approach carriers clinician Clinicians clinics collected college Community COVID-19 COVID-19 pandemic cross-contamination determine Diagnosis endoscope European Factor flexible Flexible nasendoscopy Guidance healthcare healthcare professionals ICU impacted indication language less Local National national guideline NHS operating theatre Patient care patients performed PPE procedure protocol raised reduction in reflected reported required response resulting speech surgeon therapist upper Upper aerodigestive tract. Volume [DOI] 10.1186/s12913-021-07416-x PMC 바로가기 [Article Type] Observational Study
The Current Landscape of mRNA Vaccines Against Viruses and Cancer-A Mini Review바이러스 및 암에 대한 mRNA 백신의 현재 상황-A 미니 리뷰Review Published on 2022-05-062022-09-11 Journal: Frontiers in Immunology [Category] 유전자 메커니즘, [키워드] Against Cancer cancer vaccination cancers cause clinical development clinical trial clinical trials clinical trials of mRNA vaccines COVID-19 pandemic current death example flexible landscape limitation MINI molecular mechanisms mRNA mRNA modifications mRNA vaccine mRNA vaccine delivery mRNA vaccine developers mRNA vaccine mechanism mRNA vaccines mRNA-based multiple antigen multiple antigens Patient Personalized medicine platform Research review therapy Treatment vaccination vaccine platform viral disease viral infection viral infections viral vaccination. viruses [DOI] 10.3389/fimmu.2022.885371 PMC 바로가기 [Article Type] Review
Ex vivo and in vivo suppression of SARS-CoV-2 with combinatorial AAV/RNAi expression vectors조합 AAV/RNAi 발현 벡터를 사용한 SARS-CoV-2의 생체외 및 생체내 억제Article Published on 2022-05-042022-09-11 Journal: Molecular therapy : the journal of the American So [Category] COVID19(2023년), SARS, 변종, 치료제, [키워드] AAV acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition adeno-associated virus Antiviral Antiviral agents antiviral RNAi Cell clinically cocktail complement coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 disease symptom effective escape mutant escape mutants experiment expression vector flexible Genetic global effort Gut hACE2 in vivo infected cell infected cells intestinal cells intranasal mice mutational escape. N gene N genes organoids pandemic prevented RdRP RNA RNAi SARS virus SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RdRp SARS-CoV-2 strains severe acute respiratory syndrome Coronavirus suppressed the SARS-CoV-2 therapeutic translation triggers Vaccine vector vectors viral adaptation Viral load viral loads virus wild-type [DOI] 10.1016/j.ymthe.2022.01.024 PMC 바로가기 [Article Type] Article
International Association for the Study of Lung Cancer Study of the Impact of Coronavirus Disease 2019 on International Lung Cancer Clinical TrialsResearch article Published on 2022-05-012022-10-05 Journal: International Journal of Molecular Sciences [Category] 임상, [키워드] Action aggregate approach clinical clinical trial clinical trials collected Collection Compliance coronavirus disease COVID-19 COVID-19 pandemic declined decrease effective eligible patient Enrollment evaluate the effect evaluated flexible Impact IMPROVE investigator Laboratory lung cancer medication Mitigation MOST not significantly different occurred pandemic protocol reductions in required Result significant decrease Site survey Symptom Travel Trial trials were used worsened [DOI] 10.1016/j.jtho.2022.01.017 [Article Type] Research article
Bi-ECDAQ: An electrochemical dual-immuno-biosensor accompanied by a customized bi-potentiostat for clinical detection of SARS-CoV-2 Nucleocapsid proteinsBi-ECDAQ: SARS-CoV-2 뉴클레오캡시드 단백질의 임상 검출을 위한 맞춤형 이중-전위기(bi-potentiostat)와 함께 제공되는 전기화학적 이중 면역 바이오센서Article Published on 2022-05-012022-09-11 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 치료기술, 치료법, [키워드] accompanied acquisition active site active sites All-in-one data acquisition platform approach Bi-potentiostat readout system carboxyl comparable complex COVID-19 COVID-19 patient Data acquisition diagnostics Diseases Dual working screen-printed electrode Electrochemical immunosensing eliminating flexible functional incompatible lack limit of detection matrix effect N-protein Nasopharyngeal swab nasopharyngeal swab sample nucleocapsid protein offered performed point-of-care Protein Recognition resulting SARS-CoV-2 SARS-CoV-2 nucleocapsid SARS-CoV-2 nucleocapsid protein Screen sensitive assay sensitivity significantly lower unmet need [DOI] 10.1016/j.bios.2022.114018 PMC 바로가기 [Article Type] Article
Abstract task representations for inference and controlReview article Published on 2022-04-222022-10-05 Journal: Trends in Cognitive Sciences [Category] 비임상, [키워드] Abstract abstraction arising behavioral flexibility Brain build cognitive cognitive control cognitive map cortical Decision-making dorsolateral prefrontal cortex entorhinal cortex facilitate flexible frontoparietal cortex generalization hippocampus Hypothesis implicated implication Inference knowledge learning maintain medial temporal lobe memory observation orbitofrontal cortex production rule reinforcement learning representing Research rostrolateral prefrontal cortex ventromedial prefrontal cortex [DOI] 10.1016/j.tics.2022.03.009 [Article Type] Review article
Covid-19 threat and coping: application of protection motivation theory to the pandemic experiences of people affected by amyotrophic lateral sclerosisCovid-19 위협과 대처: 근위축성 측삭 경화증의 영향을 받는 사람들의 전염병 경험에 보호 동기 이론 적용Article Published on 2022-04-122022-09-11 Journal: BMC Neurology [Category] COVID19(2023년), SARS, 변종, [키워드] adaptation affected ALS Amyotrophic lateral sclerosis Analysis analyzed approach benefit Canada Care clinical care communication contributed coping COVID 19 COVID-19 infection COVID-19 pandemic determine Emergency Emergency planning engage expressed Families family Family caregivers finding flexible group Health health authorities health systems Healthcare systems high risk identify Infection information Interaction introduced investigated lack Lateral Sclerosis media Medical care mitigate motivation outcome pandemic Pandemics participant pathway Patient patients populations professional protection Protective Protective motivation theory. provided public health recommendation recruited Region Support Telemedicine theory threat Vaccines variant [DOI] 10.1186/s12883-022-02662-w PMC 바로가기 [Article Type] Article