COVID‐19 and vertical transmission: assessing the expression of ACE2/TMPRSS2 in the human fetus and placenta to assess the risk of SARS‐CoV‐2 infectionResearch Article Published on 2021-11-182022-10-28 Journal: BJOG : an international journal of obstetrics and [Category] COVID-19, MERS, SARS, [키워드] Abstract ACE2 Adults amniotic analysed Analysis children concerning COVID‐19 COVID‐19 infection COVID‐19 dataset epithelial explain expressed expression fetal fetal infection finding gastrointestinal tract help immunohistochemistry indicate Infection intestine kidney lung performed Placenta presenting Protein protein expression protein level Proteins provide Repository required Retrospective analysis risk SARS‐CoV‐2 infection SARS‑CoV2 SARS‐COV2 scRNAseq significant level Single Cell susceptibility susceptible tissue tissues TMPRSS2 Transmission unlikely vertical transmission virus women [DOI] 10.1111/1471-0528.16974 PMC 바로가기 [Article Type] Research Article
Ace2 and Tmprss2 Expressions Are Regulated by Dhx32 and Influence the Gastrointestinal Symptoms Caused by SARS-CoV-2Article Published on 2021-11-162022-10-30 Journal: Journal of Personalized Medicine [Category] COVID-19, [키워드] ACE2 receptor Analysis approach associations BXD mice cellular entry chromosome 7 co-expression Control coronavirus disease covariation COVID-19 COVID-19 disease demonstrated expressed expression Gastrointestinal gastrointestinal tract Genetic genetics GI tissue implication indicated influence Interaction locus microbiota molecular molecular mechanism mRNA expression network analysis pathogenesis of COVID-19 pathway priming Protein quantified Quantitative SARS-CoV-2 SARS-COV-2 infection significantly Strains suggested systems genetics the spike protein the timing TMPRSS2 traits transcript Transcriptome Treatment [DOI] 10.3390/jpm11111212 PMC 바로가기 [Article Type] Article
Future Trends in Semiconducting Gas-Selective Sensing Probes for Skin Diagnostics피부 진단을 위한 반도체 가스 선택적 감지 프로브의 미래 동향Perspective Published on 2021-11-132022-09-10 Journal: Sensors (Basel, Switzerland) [Category] MERS, SARS, 바이오마커, 치료기술, [키워드] acetone alcohols ammonia Asthma Biomarker Biomarkers blood stream bowel Breast breath can be used cancers carbon monoxide cholesterol chronic obstructive chronic obstructive pulmonary disease Colitis Colon Compound conditions cystic fibrosis diabete diabetes diagnostics disease Diseases effective fibrosis flu Focusing Future gastrointestinal tract heart disease ICU Patients include Infection Infectious diseases irritable bowel syndrome isoprene life lung Metabolic diseases monitoring Nanotechnology Neurological diseases nitric oxide obesity obstructive pulmonary disease pancreatic Pneumonia pulmonary diseases Quality of life skin skin gas sleep apnea syndrome the disease trend unique urinary tract infections variety [DOI] 10.3390/s21227554 PMC 바로가기 [Article Type] Perspective
Vaccination against SARS-CoV-2 in Patients with Inflammatory Bowel Diseases: Where Do We Stand?Review Published on 2021-11-112022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] acute respiratory distress acute respiratory syndrome approach ARDS circulation Complication coronavirus disease Coronavirus-2 Course COVID-19 Crohn’s disease Crohn’s disease effective Effectiveness expected gastrointestinal tract greater IBD Immunocompromised immunological immunosuppressive therapies immunosuppressive therapy Infection Inflammation Inflammatory bowel disease knowledge management medication pandemic pathogen Pathogens Patient patients provide reducing risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination severe disease course shown subject syndrome Therapeutic approach ulcerative colitis underlying condition vaccination Vaccine vaccine response [DOI] 10.3390/life11111220 PMC 바로가기 [Article Type] Review
Pathogenesis and Mechanism of Gastrointestinal Infection With COVID-19Immunology Published on 2021-11-102022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] ACE2 acute respiratory syndrome Angiotensin-converting enzyme 2 (ACE2) Anti-inflammatory cause caused Cell cellular receptor coronavirus Coronavirus disease 2019 (COVID-19) COVID-19 cytokine release Cytokine storm decrease downregulation dysfunction enzyme expressing expression functional Gastrointestinal Gastrointestinal symptom gastrointestinal symptoms gastrointestinal tract gut–lung axis immune response infect Infectious disease Interaction intestinal intestinal epithelial cell intestinal epithelial cells Local mechanism outbreak pathological mechanism Patient prognosis of patients Pulmonary infection RAS RAS system recent replicated respiratory tract SARS-CoV SARS-CoV-2 SARS-COV-2 infection Spread target tissue viral infection virus cycle [DOI] 10.3389/fimmu.2021.674074 PMC 바로가기 [Article Type] Immunology
SARS-CoV-2 and the role of orofecal transmission: a systematic reviewSARS-CoV-2와 구강내 전파의 역할: 체계적인 검토Systematic Review Published on 2021-11-022022-09-11 Journal: F1000Research [Category] MERS, SARS, 유전자 메커니즘, 치료기술, [키워드] addition articles average Case series case sery China Cohort cohort study Contact content COVID-19 COVID-19 diagnosis COVID-19 patients criteria Culture demonstrated Diagnosis Dynamics epithelial cells Evidence fecal fecal samples feces FIVE gastrointestinal disease gastrointestinal tract Google Google Scholar include individuals with COVID-19 infect infectious dose Infectious virus intestinal epithelial cells Invasion medRxiv mode observational studies observational study open Orofecal patients positive public health Quantitative data recorded reported respiratory respiratory sample Respiratory samples review RT-PCR SARS-CoV-2 SARS-CoV-2 RNA Symptom systematic review tested Transmission Transmission dynamics transmission of SARS-CoV-2 transmitted Viral viral culture virus wastewater water WHO [DOI] 10.12688/f1000research.51592.2 PMC 바로가기 [Article Type] Systematic Review
Zinc as a Drug for Wilson’s Disease, Non-Alcoholic Liver Disease and COVID-19-Related Liver InjuryReview Published on 2021-10-312022-10-30 Journal: Molecules [Category] COVID-19, MERS, SARS, [키워드] affected characterized coronavirus COVID-19 COVID-19 pandemic deficiency disorder drug drug therapy Effect Elderly patient enzyme gastrointestinal tract histological human physiology indicated Infection insulin resistance introduced Liver disease metabolism Mortality non-alcoholic liver disease oxidative stress Patient positive progression recorded reducing responsible risk SARS-CoV-2 severe disease similarities susceptibility Therapeutic approach therapy transcription factors Treatment undergo Wilson’s disease Wilson’s disease Zinc zinc supplementation [DOI] 10.3390/molecules26216614 PMC 바로가기 [Article Type] Review
Protective Efficacy of Gastrointestinal SARS-CoV-2 Delivery against Intranasal and Intratracheal SARS-CoV-2 Challenge in Rhesus Macaques붉은 털 원숭이의 비강 및 기관 내 SARS-CoV-2 감염에 대한 위장 SARS-CoV-2 전달의 보호 효능Vaccines and Antiviral Agents Published on 2021-10-272022-09-12 Journal: Journal of Virology [Category] MERS, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adenovirus administration Antibody titer Bronchoalveolar lavage fluid challenge conducted coronavirus correlated Coverage COVID-19 delivery distribution Efficacy esophagogastroduodenoscopy Formulation Gastrointestinal gastrointestinal tract greater health benefits immunogenic immunogenicity intranasal intratracheal live oral vaccine Live oral vaccines live SARS-CoV-2 macaque mucosal nasal swab nasal swabs offer oral administration Oral vaccine Prophylactic Protective protective efficacy public health Rectal swabs respiratory viruses rhesus macaque rhesus macaques route SARS-CoV-2 serotype Serum neutralizing antibody severe acute respiratory syndrome Coronavirus timelines Vaccine Vaccines Viral load virus replication [DOI] 10.1128/JVI.01599-21 PMC 바로가기 [Article Type] Vaccines and Antiviral Agents
Cathepsin L, transmembrane peptidase/serine subfamily member 2/4, and other host proteases in COVID-19 pathogenesis – with impact on gastrointestinal tractArticle Published on 2021-10-212023-06-16 Journal: World journal of gastroenterology [Category] MERS, SARS, [키워드] angiotensin converting enzyme 2 cathepsin L COVID-19 gastrointestinal tract SARS-CoV-2 Transmembrane peptidase/serine subfamily member 2/4 [DOI] 10.3748/wjg.v27.i39.6590 PMC 바로가기
Infection of Human Cells by SARS-CoV-2 and Molecular Overview of Gastrointestinal, Neurological, and Hepatic Problems in COVID-19 PatientsReview Published on 2021-10-202022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] ACE2 alteration angiotensin-converting enzyme-2 Brain cell receptors coronavirus disease 19 COVID-19 COVID-19 patient Diseases disorder events Evidence explained expression Gastrointestinal gastrointestinal tract Gut gut flora help hepatic hepatic derangements higher risk Host Human infected with SARS-CoV-2 Infection intestinal permeability likelihood liver liver cells Lungs manifestation Microbiome molecular mechanism neurological Neurological symptoms overexpressed pandemic Pathogens pathophysiological problem recent receptor SARS-CoV-2 SARS-COV-2 infection severe COVID-19 Spike protein suggested [DOI] 10.3390/jcm10214802 PMC 바로가기 [Article Type] Review