Drug Repurposing to Identify Nilotinib as a Potential SARS-CoV-2 Main Protease Inhibitor: Insights from a Computational and In Vitro Study잠재적인 SARS-CoV-2 주요 프로테아제 억제제로 닐로티닙을 식별하기 위한 약물 용도 변경: 전산 및 시험관 연구에서 얻은 통찰력Article Published on 2021-11-222022-09-11 Journal: Journal of Chemical Information and Modeling [Category] SARS, 신약개발, 치료제, [키워드] 6LU7 active site Analysis antiviral activity antiviral therapeutics Bank bemcentinib binding affinity binding energy Cell culture computer-aided drug design COVID-19 database drug Drug Bank drug candidate drug design Drug repurposing drugs experiment Glu166 high accuracy His41 independent indication inhibitor insight Interaction M pro MD simulation MD simulations medication molecular molecular docking molecular dynamics Molecular dynamics simulation Nilotinib pandemic Partial Potential predicted repurposing researcher SARS-CoV-2 sequence significantly strength subset suggested the binding affinity the SARS-CoV-2 Viral pneumonia Virtual screening was performed were measured [DOI] 10.1021/acs.jcim.1c00524 PMC 바로가기 [Article Type] Article
Social stress drives the multi-wave dynamics of COVID-19 outbreaksArticle Published on 2021-11-182022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, SARS, [키워드] change classical Combination Computational models Concentration country COVID-19 outbreak COVID-19 pandemic described effort Epidemic Epidemics Evolution explain Factors Features First wave help high accuracy Human behaviour Immunity Infectious diseases intrinsic kinetic maintain management Nonlinear phenomena outbreak over predict profile Psychology and behaviour second wave Stage statistical Stress syndrome the epidemic vaccination virus [DOI] 10.1038/s41598-021-01317-z PMC 바로가기 [Article Type] Article
Detection of Fake News Text Classification on COVID-19 Using Deep Learning Approaches딥 러닝 접근 방식을 사용하여 COVID-19에 대한 가짜 뉴스 텍스트 분류 감지Research Article Published on 2021-11-152022-09-11 Journal: Computational and Mathematical Methods in Medicine [Category] MERS, SARS, 치료기술, [키워드] Algorithm Analysis applied approach Bayesian classification CNN Confusion confusion matrix COVID-19 dataset Decision tree deep deep learning detection eight evaluated fake news help high accuracy inverse document frequency learning Logistic regression machine-learning measure media New predict provided Python random Random forest recommendation Research researcher researchers social media Support support vector machine term frequency tested text tokenization true positive Weighting [DOI] 10.1155/2021/5514220 PMC 바로가기 [Article Type] Research Article
Bioaerosol monitoring by integrating DC impedance microfluidic cytometer with wet-cyclone air samplerDC 임피던스 미세유체 세포계측기와 습식 사이클론 공기 샘플러를 통합하여 바이오에어로졸 모니터링Article Published on 2021-11-152022-09-11 Journal: Biosensors & bioelectronics [Category] SARS, 치료기술, [키워드] addition aerosol Aerosols Air monitoring antibody Bacteria Bacterial bioaerosol build COVID-19 cyclone cytometer Cytometry DC impedance analysis dead detect detection efficiency Device differentiation disease dust E. coli Efficiency Escherichia coli fluorescent high accuracy Microfluidic chip MONITOR outbreak Particle Particles pathogen detection performed Research seriousness shown solvent Usage viability was tested was used Wet-cyclone. [DOI] 10.1016/j.bios.2021.113499 PMC 바로가기 [Article Type] Article
COVID-19 diagnosis from chest x-rays: developing a simple, fast, and accurate neural networkResearch Published on 2021-10-122022-10-31 Journal: Health Information Science and Systems [Category] COVID-19, [키워드] Accuracy added artificial intelligence assist baseline calculated caused Chest chest imaging chest X-ray chest X-rays classification clinician CNN CNNs convolution neural network COVID-19 COVID-19 diagnosis database deep learning demonstrated diagnose diagnosis of COVID-19 diagnostic diagnostic decision early stage help high accuracy IMPROVE lung Lungs Negative predictive value Novel coronavirus overcome overfitting Positive predictive value Radiography recent Research Result sensitivity specificity supplementary material Support test dataset tested the disease used data Viral pneumonia viral pneumonias X-ray [DOI] 10.1007/s13755-021-00166-4 PMC 바로가기 [Article Type] Research
A Continuously Benchmarked and Crowdsourced Challenge for Rapid Development and Evaluation of Models to Predict COVID-19 Diagnosis and HospitalizationResearch Published on 2021-10-112022-10-29 Journal: JAMA Network Open [Category] COVID-19, MERS, [키워드] 95% CI age Algorithm all age groups Analysis approach AUROC build challenge characteristic Community conducted COVID-19 COVID-19 diagnosis COVID-19 patient COVID-19 test COVID-19 testing cumulative data set development Diagnosis diagnostic discrepancies effort evaluated female group finding Generalizability high accuracy Hospitalization Hospitalized Importance likelihood limitation machine machine learning model male group measure Model objective outcome outcomes pandemic participant Patient patient data Point positive COVID-19 Precision predict Probability prognostic provide Rapid recall receiving Relevance Result setting severity Sex stratified subgroup subgroups submitted University of Washington was obtained [DOI] 10.1001/jamanetworkopen.2021.24946 PMC 바로가기 [Article Type] Research
AI-driven prediction of SARS-CoV-2 variant binding trends from atomistic simulationsRegular Article - Living Systems Published on 2021-10-062022-10-31 Journal: The European Physical Journal. E, Soft Matter [Category] COVID-19, SARS, [키워드] Abstract Algorithm applied binding binding affinity high accuracy molecular Mutation predict receptor ACE2 SARS-CoV-2 variant several variant Spike protein subset the SARS-CoV-2 [DOI] 10.1140/epje/s10189-021-00119-5 PMC 바로가기 [Article Type] Regular Article - Living Systems
Detection and analysis of COVID-19 in medical images using deep learning techniques딥 러닝 기술을 사용한 의료 이미지에서 Covid-19의 탐지 및 분석Article Published on 2021-10-042022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 치료기술, [키워드] Accuracy addition Algorithm Algorithms Analysis applied automatically best binary classification CNN Computer science COVID-19 COVID-19 diagnosis CT-scan datasets deep learning detection Diagnosis diagnosis of COVID-19 faster help high accuracy imaging IMPROVE outbreak overcome parameter performed Pneumonia radiologist Radiologists Respiratory tract diseases transfer Validity were assessed X-ray [DOI] 10.1038/s41598-021-99015-3 PMC 바로가기 [Article Type] Article
A Portable RT-LAMP/CRISPR Machine for Rapid COVID-19 Screening빠른 COVID-19 스크리닝을위한 휴대용 RT-LAMP/CRISPR 기계Communication Published on 2021-10-022022-09-01 Journal: Biosensors [Category] 진단, 치료기술, [키워드] changed COVID-19 COVID-19 pandemic CRISPR detect Device diagnose Diseases Eppendorf followed by high accuracy individual infected with SARS-CoV-2 Infectious diseases isothermal amplification limit of detection lockdown lockdowns Loop-mediated isothermal amplification machine mandatory methodology microliter mounted PCR point of care testing preventative measures printed circuit board Rapid rapid diagnostics reduce reverse transcription SARS-CoV-2 SARS-CoV-2 detection Screening social distancing Society temperature virus [DOI] 10.3390/bios11100369 PMC 바로가기 [Article Type] Communication
A Portable RT-LAMP/CRISPR Machine for Rapid COVID-19 ScreeningCommunication Published on 2021-10-022022-10-27 Journal: Biosensors [Category] COVID-19, [키워드] changed COVID-19 COVID-19 pandemic detect diagnose Diseases Eppendorf high accuracy individual infected with SARS-CoV-2 isothermal amplification limit of detection lockdown machine mandatory methodology mounted PCR point of care testing preventative measures Rapid rapid diagnostics reduce reverse transcription SARS-CoV-2 SARS-CoV-2 detection Screening social distancing temperature virus [DOI] 10.3390/bios11100369 PMC 바로가기 [Article Type] Communication