Challenges in Fusarium, a Trans-Kingdom Pathogen퓨사리움, 초왕국 병원체의 도전 과제journal-article Published on 2016-04-012024-07-29 Journal: Mycopathologia [Category] 백선증, [키워드] Fusariosis Fusarium taxonomy human pathogen plant pathogen Refraction to treatment. [DOI] 10.1007/s11046-016-9993-7 [Article Type] journal-article
Estimation of the Basic Reproductive Number and Mean Serial Interval of a Novel Pathogen in a Small, Well-Observed Discrete PopulationResearch Article Published on 2016-02-052022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, 신종인플루엔자, [키워드] Algorithm arising basic basic reproductive number Combination Discrete distribution Epidemic estimate estimation Extensive Final finding generate growth human pathogen incidence initial interval Intervention less likelihood novel number outbreak parameter parameters pathogen Population populations public health real time recent required susceptible the timing Transmissibility unique [DOI] 10.1371/journal.pone.0148061 PMC 바로가기 [Article Type] Research Article
Middle East Respiratory Syndrome Coronavirus Intra-Host Populations Are Characterized by Numerous High Frequency VariantsResearch Article Published on 2016-01-202022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, [키워드] average coverage binding consensus sequences cross deep epidemiological Evidence Frequency Genome greater host range Human human pathogen Infection majority mechanism MERS virus MERS-CoV Middle East Mutation Nasal sample Numerous pandemic phenotype Population primer probe question Region respiratory respiratory syndrome coronavirus SARS virus sensitivity sequencing data Single nucleotide variant susceptibility Transmission variant virus was obtained [DOI] 10.1371/journal.pone.0146251 PMC 바로가기 [Article Type] Research Article
Inferring the hosts of coronavirus using dual statistical models based on nucleotide compositionArticle Published on 2015-11-262022-10-29 Journal: Scientific Reports [Category] Coronavirus, MERS, [키워드] acute respiratory syndrome approach caused coronavirus Coronaviruses high accuracy Host human pathogen humans MERS-CoV Middle East nucleotide Panic parameter prediction researchers respiratory syndrome coronavirus SARS-CoV spike gene statistical model Support SVM training data Transmission [DOI] 10.1038/srep17155 PMC 바로가기 [Article Type] Article
Diversity of coronavirus in bats from Eastern ThailandShort Report Published on 2015-04-112022-10-28 Journal: Virology Journal [Category] Coronavirus, MERS, [키워드] alphacoronaviruses Analysis bat bats betacoronaviruses collected complex Consensus coronavirus CoV CoVs Cynopterus detect Diversity Eastern effort Endemic fecal finding Genetic Hipposidero hosts human pathogen imperative indicate Lineage lineage B betacoronavirus Megaderma Middle East nine PCR primer Phylogenetic preserved reactive Rectal swabs Region reported reservoir respiratory RNA Sample SARS-CoV Scotophilus Seven specimen Surveillance Taphozous Thailand transported zoonotic [DOI] 10.1186/s12985-015-0289-1 PMC 바로가기 [Article Type] Short Report
On the biased nucleotide composition of the human coronavirus RNA genomeArticle Published on 2015-02-022022-11-01 Journal: Virus research [Category] Coronavirus, [키워드] Atypical characteristic Characteristics codon usage Coronaviral coronavirus coronavirus RNA Coronaviruses domains event Evolution Genome human coronaviruses human pathogen investigated less MERS MOST nucleotide Nucleotide signature opposite proportion Region RNA RNA genome SARS sequence single-stranded vessels viral genome viral RNA genome virus virus isolate viruses zoonotic [DOI] 10.1016/j.virusres.2014.11.031 PMC 바로가기 [Article Type] Article
Vaccines against human diarrheal pathogens: current status and perspectivesarticle Published on 2014-12-312024-09-01 Journal: Human vaccines & immunotherapeutics [Category] 세균성이질, [키워드] Diarrheal diseases human pathogen Oral vaccine recombinant vaccine rotavirus Shigellaspp. Campylobacterspp Vibrio cholerae [Article Type] article
Analysis of the Genome and Transcriptome of Cryptococcus neoformans var. grubii Reveals Complex RNA Expression and Microevolution Leading to Virulence AttenuationCryptococcus neoformans var.의 게놈 및 전사체 분석 grubii, 복잡한 RNA 발현 및 독성 약화로 이어지는 소진화를 밝혀냄Research Article Published on 2014-04-172022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] a major addition alternative polyadenylation Analysis analyzed annotation attenuation automated C. neoforman CDS chromosomal coding coding DNA sequence coding DNA sequences Comparative analysis Cryptococcus Cryptococcus neoforman Cryptococcus neoformans death Efficiency examination expressed gene expressed genes feature fungi Gene Expression Genes Genetic genetics Genome genome sequence genomic studies genomic study human pathogen identify Immunocompromised Immunocompromised patients in vitro culturing indicate intron introns involved isolate isolates Laboratory leading manual curation meningoencephalitis microevolution microevolutionary miscRNA miscRNAs molecular motif Mutation Non-coding RNAs occur opportunistic pathogen pathogen pathogenic performed phenotypic phenotypic and genome re-sequencing analysis polyadenylation site polyadenylation sites provide Region Regulation Replication representing responses responsible resulting RNA RNA-Seq-based analysis sequence sequenced sequences Sequencing serotype Spectrum strain Stress stress responses Transcription Transcriptome untranslated regions UTRs VAR variant variety virulence yeast [DOI] 10.1371/journal.pgen.1004261 PMC 바로가기 [Article Type] Research Article
Approaching the Functional Annotation of Fungal Virulence Factors Using Cross-Species Genetic Interaction Profiling종간 유전적 상호작용 프로파일링을 사용하여 진균 독성 인자의 기능적 주석 접근Research Article Published on 2012-12-272022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] accurate AIDS analyzed annotation approach Author C. neoforman C. neoformans C. neoformans gene C. neoformans genes calculation Cancer Cell cell surface Chemotherapy compared conserved correlated correlation correlations Cryptococcus neoforman Cryptococcus neoformans death deletion mutant deletion mutants demonstrated develop disease enhancement expressed expression Factor found function functional functional annotation fungal fungal pathogens fungi Gene gene deletion gene function Genetic genetic interaction genetic interactions Golgi Golgi apparatus growth HIV/AIDS HIV/AIDS patients human pathogen identify immunostimulatory individuals Infection inhibiting Interaction interactions lack mannose molecular mutant Organ transplant organism Organisms ortholog pathogen pathogenicity pathogenicity protein Pathogens patients phagocytosis predict predicted profile profiles Profiling promote quantification Quantitative recipient required S. cerevisiae Saccharomyces cerevisiae sequence supported suppression susceptible tested the cell understanding utility validation virulence virulence gene yeast [DOI] 10.1371/journal.pgen.1003168 PMC 바로가기 [Article Type] Research Article
The Regulatory Network of Natural Competence and Transformation of Vibrio choleraeVibrio cholerae의 자연적 능력 및 변형의 규제 네트워크Research Article Published on 2012-06-212022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] a major Analysis aquatic bacterium aquatic environment assays Author autoinducers Bacteria Bacterial bacterium CAMP carbon Carbon catabolite repression catabolite repression Cell chitin chitinous chitinous exoskeleton colonization Combination competence condition conditions consequence contribute Degradation degradation products dependent on determine developmental different DNA ecological environmental niche environmental reservoirs Evidence Evolution Express expression pattern Extracellular Factor found Gene Gene Expression gene transfer Genes Genetic genetic transformation genomes growth heterogeneity heterogeneous homogeneous horizontal gene Horizontal gene transfer human pathogen immunological detection initiate intracellular signaling investigated involved lead maintenance majority metabolism mode natural Natural competence natural transformation network organism pathogenic phenotype protein level protein levels quantitative RT–PCR quorum-sensing pathways regions regulated regulatory circuit released reporter fusions required signaling cascade signaling pathway single cell level tested TfoX the cells transcriptional transfer transformation V. cholerae Vibrio cholerae western blot Western blot analysis zooplankton [DOI] 10.1371/journal.pgen.1002778 PMC 바로가기 [Article Type] Research Article