[Effect of IFN-γ and IL-12 expressions on intrauterine transmission in HBsAg-positive parturientsin late pregnancy]Article Published on 2019-09-102023-06-18 Journal: Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi [Category] B형 간염, [키워드] Dominate infection HBV IFN-γ IL-12 Occult infection [DOI] 10.3760/cma.j.issn.0254-6450.2019.09.011
A Functional Food Mixture “Protector” Reinforces the Protective Immune Parameters against Viral Flu Infection in MiceArticle Published on 2018-06-082023-06-08 Journal: Nutrients [Category] Fulltext, 신종인플루엔자, [키워드] dates figs flu infection flu vaccine ginger hemagglutination inhibition antibodies IFN-γ IL-12 IL-22 IL-6 olive fruit Pomegranate red grape [DOI] 10.3390/nu10060743 PMC 바로가기 [Article Type] Article
Functional analyses of the interaction of chicken interleukin 23 subunit p19 with IL-12 subunit p40 to form the IL-23 complexarticle Published on 2017-12-312024-09-01 Journal: Molecular Immunology [Category] 살모넬라증, [키워드] chicken cytokine IL-12 IL-23 signaling pathway [Article Type] article
The relative contribution of DNA methylation and genetic variants on protein biomarkers for human diseases인간 질병에 대한 단백질 바이오마커에 대한 DNA 메틸화 및 유전적 변이의 상대적 기여도Research Article Published on 2017-09-152022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] adjusted Affect allele alteration analyses analyzed association Biomarker Biomarkers Cancer cardiovascular disease cardiovascular diseases caused copy CXCL11 CXCL9 disease disease pathogenesis disease status disease-associated Diseases DNA methylation DNA methylation level DNA methylation levels driven by Effect effect size effect sizes effective environmental factor environmental factors Epigenetic Evidence expression expression patterns Factor Genes Genetic Genetic variant genetic variants Genetic variation Genome Genome-wide association study genomic position GWAS Human human disease human diseases IL-12 IL-18 Inflammation loci locus Modification MOST NLRC5 overlapped Pathogenesis performed phenotypic Protein risk smoking SNP SNPs trans unique Variation were measured while [DOI] 10.1371/journal.pgen.1007005 PMC 바로가기 [Article Type] Research Article
Synergistic effect of IL-12 and IL-18 induces TIM3 regulation of γδ T cell function and decreases the risk of clinical malaria in children living in Papua New GuineaIL-12와 IL-18의 시너지 효과가 파푸아뉴기니에 거주하는 어린이의 γδ T 세포 기능에 대한 TIM3 조절을 유도하고 임상 말라리아 위험을 감소시킵니다.Research Article Published on 2017-06-152024-08-12 Journal: BMC Medicine [Category] 말라리아, [키워드] IL-12 IL-18 malaria Plasmodium TIM3 γδ T cells [DOI] 10.1186/s12916-017-0883-8 PMC 바로가기 [Article Type] Research Article
The protective effects of intranasal administration of IL-12 given before influenza virus infection and the negative effects of IL-12 treatment given after viral infectionArticle Published on 2016-09-012023-06-24 Journal: Journal of medical virology [Category] 신종인플루엔자, [키워드] IL-12 influenza virus infection myeloid-derived suppressor cell (MDSC). NK cell [DOI] 10.1002/jmv.24494
Briakinumab for Treatment of Crohn’s Disease: Results of a Randomized TrialOriginal Clinical Article Published on 2015-04-292024-09-04 Journal: Inflammatory Bowel Diseases [Category] 대상포진, [키워드] IL-12 IL-23 monoclonal antibody [DOI] 10.1097/MIB.0000000000000366 PMC 바로가기 [Article Type] Original Clinical Article
Mendelian susceptibility to mycobacterial disease: genetic, immunological, and clinical features of inborn errors of IFN-γ immunity결핍성 미코박테리아 질환에 대한 멘델리안 감수성: IFN-γ 면역의 선천적 결함의 유전적, 면역학적 및 임상적 특징Article Published on 2014-12-042024-08-19 Journal: Seminars in immunology [Category] 살모넬라증, [키워드] BCG IFN-γ IL-12 ISG15 mycobacteriosis Primary Immunodeficiency Tuberculosis [DOI] 10.1016/j.smim.2014.09.008 PMC 바로가기 [Article Type] Article
Mouse Hepatitis Virus Infection Upregulates Genes Involved in Innate Immune ResponsesResearch Article Published on 2014-10-312022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, [키워드] activated Activation acute phase Affymetrix Analysis binding calcium ion caused CD11b CD19 CD4 CD52 CD68 CD74 CD8 Cell cellular changes in CNS contribute demonstrated Demyelination expression IFN-γ IL-12 increased expression induce Infection Inflammation inflammatory mediator Innate Local maturation mice microenvironment microglia morphology mouse mRNA expression myelin sheath phagocytosis regulate released response reveal robust significantly turn upregulated viral replication [DOI] 10.1371/journal.pone.0111351 PMC 바로가기 [Article Type] Research Article
Distinct Immune Response in Two MERS-CoV-Infected Patients: Can We Go from Bench to Bedside?Research Article Published on 2014-02-142022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, [키워드] absence adaptive Adaptive immune response Antigen presentation Antiviral approach BAL Bench Can Cell chemokine compared Consensus control patients coronavirus Critical cytokine decrease determine died different dsRNA early stage enzyme-linked immunosorbent highlight humans IFN IFNα IFNγ IL-12 IL-17 immune response impair in vitro Infected infected patient Infection initial intensive care involved mechanism MERS-CoV MERS-CoV infection Middle East National Occurrence outcome Patient polymerase chain promote respiratory response RNA robust secretion sera supernatant therapeutic approaches Treatment viral dsRNA viruses was performed were used World Health Organization [DOI] 10.1371/journal.pone.0088716 PMC 바로가기 [Article Type] Research Article