Modeling the effects of contact-tracing apps on the spread of the coronavirus disease: Mechanisms, conditions, and efficiency코로나 바이러스 질병의 확산에 대한 접촉 추적 앱의 효과 모델링 : 메커니즘, 조건 및 효율성Research Article Published on 2021-09-012022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 치료기술, [키워드] can not Characteristics comprehensive analysis conditions Containment coronavirus coronavirus disease COVID-19 detect Effect Effectiveness Efficiency ENhance fixed individual individuals infectious Japan modeling per day quarantine second Spread tested virus [DOI] 10.1371/journal.pone.0256151 PMC 바로가기 [Article Type] Research Article
Airborne transmission of respiratory viruses호흡기 바이러스의 공중 전염Review Published on 2021-08-272022-09-10 Journal: Science (New York, N.y.) [Category] MERS, SARS, 유전자 메커니즘, [키워드] activities acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 advance aerosol aerosol transmission Aerosols affected affecting airflow alveolar breathing can not CDC center characterized Contact contact with contaminated surface contaminated surfaces contribute Control coronavirus cough coughing coughs COVID-19 COVID-19 pandemic CREDIT Critical defined description disease control Diseases distance dominant droplet droplets emitter enrichment environmental factors Evidence exhale experiments expiratory exposure to Factor filtration fomite fraction Frequency Health Organization Height Host hosts Human rhinovirus Improved increasingly individual infected individual infected individuals infecting Infection infectious infectious viruses Influenza Influenza virus inhalation Inhaled Intervention involved knowledge lack less limitation Lungs majority Mask Masks measure Measures mechanism MERS Middle East Middle East respiratory syndrome mitigate new infection new infections occur other respiratory virus Other respiratory viruses Outbreaks pandemic pathogen Pathogens pathway penetrate phase Physicochemical properties physicochemical property prevalent prevention produced provided Radiation reduce relative contribution relative contributions Relative humidity respiratory respiratory aerosols respiratory droplet Respiratory droplets respiratory infections respiratory pathogen Respiratory pathogens respiratory syncytial virus respiratory tract respiratory virus respiratory viruses review rhinovirus robust RSV SARS-CoV SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus shown sneeze sneezes Spread superspreading event syndrome temperature thought through contact Transmission transmission of SARS-CoV-2 transmission pathway transmission pathways transmitted Transport transported Travel ultraviolet Ultraviolet radiation upper airway velocity Ventilation virus viruses WHO World Health Organization [DOI] 10.1126/science.abd9149 PMC 바로가기 [Article Type] Review
Seroconversion and fever are dose-dependent in a nonhuman primate model of inhalational COVID-19혈청 전환 및 발열은 흡입 COVID-19의 비인간 영장류 모델에서 용량 의존적Research Article Published on 2021-08-232022-09-10 Journal: PLoS Pathogens [Category] MERS, 변종, 치료기술, [키워드] 95% CI aerosol transmission age animals Asymptomatic baseline Clinical sign Clinical signs Comorbidities COVID-19 dependent on develop disease disease transmission dose dose-dependent Efficacy Evidence exposure dose Factor Factors Fever healthy humans immune response Infection infectious infectious dose inhalation limit masking median nasopharyngeal oropharyngeal swabs Probability provided public health measure public health measures resulting SARS-CoV-2 SARS-COV-2 infection Seroconversion significantly lower social distancing Spread subsequent subset TCID the median Therapeutics These data transmission of SARS-CoV-2 Vaccine Ventilation Viral viral variant virus while [DOI] 10.1371/journal.ppat.1009865 PMC 바로가기 [Article Type] Research Article
Comparison of the Modified Centers for Disease Control and Prevention 2019-Novel Coronavirus Real-Time RT-PCR Method for Detection of Infectious and Heat-Inactivated Virus on Stainless Steel수정된 질병통제예방센터 2019-신종 코로나바이러스 실시간 RT-PCR 방법으로 스테인리스강의 감염성 및 열불활성화 바이러스 검출 비교Article Published on 2021-08-202022-09-11 Journal: Journal of AOAC International [Category] SARS, 치료기술, [키워드] 2019-nCoV Aliquots alternative method alternative methods analyzed biosafety level BSL-3 facility CDC center chain Chain Reaction Control demonstrated detection disease control Emergency expected extension genomic heat heat-inactivated Highlights in viral infectious Infectious virus Level medium mitigate no difference Novel coronavirus Panel POD polymerase chain reaction positive result prevention Probability qPCR reaction Real time reverse transcription polymerase chain reaction respiratory response Result resulting RT-PCR RT-qPCR SARS-CoV-2 severe acute respiratory syndrome coronavirus-2 stainless steel statistical steel Study design Test time Transport transport medium validation viral stocks Viral transport medium virus virus detection VTM was used [DOI] 10.1093/jaoacint/qsab046 PMC 바로가기 [Article Type] Article
Autophagy and Mitophagy-Related Pathways at the Crossroads of Genetic Pathways Involved in Familial Sarcoidosis and Host-Pathogen Interactions Induced by Coronaviruses코로나바이러스에 의해 유도된 가족성 유육종증 및 숙주-병원체 상호작용에 관여하는 유전 경로의 교차로에서 자가포식 및 미토파지 관련 경로Comparative Study Published on 2021-08-052022-09-11 Journal: Cells [Category] MERS, 변종, 유전자 메커니즘, [키워드] abnormality accumulation acid Affect aggression Analysis antiviral response applied autophagy characterized Clustering Course COVID-19 COVID-19 pandemic deleterious mutation Deleterious mutations disease evaluate Exome Factor Factors Familial function functional gateway Genetic genetic defect genetic defects genetic factors Genetic predisposition genetics hallmark healthy individuals host response Hypothesis induced infectious inflammatory process involved list list of gene Lungs mammalian mitochondrial mitophagy mTOR Mutation pathogenic variant pathway Patient protocol Rapamycin Regulation retinoic acid risk sarcoidosis SARS-CoV2 SARS-CoV2 infection shown Signaling significant enrichment TANK Binding Kinase 1 target Viral viral infection viral infections web server [DOI] 10.3390/cells10081995 PMC 바로가기 [Article Type] Comparative Study
T cell-mediated response to SARS-CoV-2 in liver transplant recipients with prior COVID-19COVID-19 이전에 간 이식 환자에서 SARS-CoV-2에 대한 T 세포 매개 반응Article Published on 2021-08-012022-09-11 Journal: American journal of transplantation : official jou [Category] MERS, SARS, 진단, 치료기술, [키워드] 1:1 acute respiratory syndrome age antigens CD4 CD8 Cell-mediated immunity cell-mediated response clinical research/practice Complication complication: infectious control group coronavirus COVID-19 COVID-19 diagnosis cytokine declining Diagnosis ELISA ICS IgG antibodies IgG responses immune immune modulation Immunosuppression immunosuppression/immune modulation impair Infection infection and infectious agents infection and infectious agents - viral infectious infectious agent infectious agents Infectious disease interferon intracellular cytokine staining inverse correlation liver Liver transplantation liver transplantation/hepatology magnitude median membrane membrane protein monitoring: immune. MOST no significant difference no significant differences p value Patient patients proportion recipient recipients respiratory response SARS-CoV-2 SARS-CoV-2 IgG antibody Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus SFU Spearman T cell were measured [DOI] 10.1111/ajt.16708 PMC 바로가기 [Article Type] Article
Long-term shedding of viable SARS-CoV-2 in kidney transplant recipients with COVID-19COVID-19가 있는 신장 이식 환자에서 생존 가능한 SARS-CoV-2의 장기 배출Article Published on 2021-08-012022-09-11 Journal: American journal of transplantation : official jou [Category] SARS, 변종, [키워드] Cell culture cell cultures clinical research/practice Complication complication: infectious COVID-19 favor Infection infection and infectious agents - viral infectious infectious agent infectious agents Infectious disease investigated Isolation kidney kidney transplant recipient kidney transplant recipients kidney transplantation/nephrology nasopharyngeal sample Nasopharyngeal samples onset of symptom PCR testing proportion RT-PCR testing SARS-CoV-2 SARS-CoV-2 RT-PCR symptom onset symptomatic symptomatic COVID-19 These data translational translational research/science variants with COVID-19 [DOI] 10.1111/ajt.16636 PMC 바로가기 [Article Type] Article
Investigation of nonsynonymous mutations in the spike protein of SARS-CoV-2 and its interaction with the ACE2 receptor by molecular docking and MM/GBSA approach분자 도킹 및 MM/GBSA 접근법을 통한 SARS-CoV-2 스파이크 단백질의 비동의적 돌연변이 및 ACE2 수용체와의 상호작용 조사Article Published on 2021-08-012022-09-11 Journal: Computers in biology and medicine [Category] SARS, 변종, 유전자 메커니즘, [키워드] ACE2 ACE2 receptor acute respiratory distress acute respiratory distress syndrome angiotensin angiotensin-converting enzyme 2 approach approaches binding binding affinity binding free energy bioinformatics caused coagulation dysfunction COVID-19 D614G develop disease docking domain examined free energy G476S help Host human cell human cells in viral Infection infectious interact Interaction investigated investigation L18F MDs MERS-CoV molecular docking molecular dynamics Molecular dynamics simulation molecular mechanism mutant mutants Mutation N501Y nonsynonymous mutation Nonsynonymous mutations pathogenic pathological mechanism Perspective RBD receptor Receptor-binding domain researcher respiratory distress responsible reveal S-protein SAR-CoV-2 SARS-CoV SARS-CoV-2 SARS-CoV-2 pandemic screened Septic shock spike Spike protein spike-protein stability syndrome the spike protein Treatment viral disease viral infection virulent [DOI] 10.1016/j.compbiomed.2021.104654 PMC 바로가기 [Article Type] Article
Viral dynamics of acute SARS-CoV-2 infection and applications to diagnostic and public health strategies급성 SARS-COV-2 감염의 바이러스 역학 및 진단 및 공중 보건 전략에 대한 적용Research Article Published on 2021-07-122022-09-10 Journal: PLoS Biology [Category] SARS, 진단, 치료기술, [키워드] 95% CI acute infections acute SARS-CoV-2 infection asymptomatic individual Asymptomatic individuals average certainty characterized clearance clinical care Concentration credible interval Cycle threshold value Decline diagnostic early stage early stages effective sensitivity followed by help identify IMPROVE individual Infection infectious initial Intervention mathematical mathematical model measure PCR testing peaked positive PCR test public health Quantitative remained reverse transcription PCR SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 viral stages Surveillance symptomatic individual symptomatic individuals Symptoms test turnaround time trajectory Viral viral clearance viral dynamics viral proliferation Viral RNA Viral RNA shedding [DOI] 10.1371/journal.pbio.3001333 PMC 바로가기 [Article Type] Research Article
SARS-CoV-2 Transmission Risk Among National Basketball Association Players, Staff, and Vendors Exposed to Individuals With Positive Test Results After COVID-19 Recovery During the 2020 Regular and Postseason2020 정규 및 포스트 시즌 동안 COVID-19 회복 후 양성 테스트 결과를 보인 개인에게 노출된 NBA 선수, 직원 및 공급업체 간의 SARS-CoV-2 전파 위험Multicenter Study Published on 2021-07-012022-09-11 Journal: JAMA Internal Medicine [Category] Fulltext, SARS, 진단, 치료기술, [키워드] activities activity ad hoc Asymptomatic center Chain Reaction Characteristics clinical Clinical data clinically collected Control COVID-19 COVID-19 case criteria cycle Cycle threshold values disease control event Health IgG antibodies index individual individuals Infection infectious Interaction involved Isolation limit of detection male occupational health outcome participated Participation PCR test PCR testing persistent polymerase chain reaction positive positive individuals positive RT-PCR positive test result Postinfection precautions prevention recommendation Regular remained required Result retrospective cohort study risk Roche RT-PCR RT-PCR test RT-PCR testing SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 IgG antibodies SARS-COV-2 infection SARS-CoV-2 test Secondary infection secondary infections Serological testing staff Support Test test results threshold value Transmission used data Vendor Viral viral dynamics Viral transmission [DOI] 10.1001/jamainternmed.2021.2114 PMC 바로가기 [Article Type] Multicenter Study