Ivermectin – Page 6 – Communicable Diseases Research

An open label randomized clinical trial of Indomethacin for mild and moderate hospitalised Covid-19 patients

경증 및 중등도 입원 코비드-19 환자를 위한 인도메타신의 공개 라벨 무작위 임상 시험

Randomized Controlled Trial

Published on 2022-04-192022-09-12
Journal: Scientific Reports [Category] COVID19(2023년), SARS, 신약개발, 임상, 진단, 치료법, 치료제,

[키워드] addition adjuvant therapies Admission adverse event afebrile anti-inflammatory drug Antiviral Arm ARMS Block randomisation blood chemistry clinical trial control arm coronavirus disease cough COVID-19 COVID-19 patient Desaturation discharge effective Efficacy and safety evaluated Fever Follow-up High-flow oxygen hospital hospitalised indomethacin Ivermectin medication Mild moderate myalgia open label Paracetamol parameters Patient patients primary endpoint profile provided randomised randomized clinical trial reported required retained Safe Secondary endpoints Standard of care Symptom symptomatic tiredness
[DOI] 10.1038/s41598-022-10370-1 PMC 바로가기 [Article Type] Randomized Controlled Trial

Pharmacological treatment of COVID-19: an opinion paper

COVID-19의 약리학적 치료: 의견서

Review

Published on 2022-04-012022-09-11
Journal: Revista española de quimioterapia : publicación [Category] COVID19(2023년), SARS, 치료제,

[키워드] adalimumab Anakinra approach AZD7442 Azithromycin Banlanivimab Baricitinib BRII-196 BRII-198 canakinumab Casirivimab Certolizumab Ciganilmab Colchicine college Committee convalescent convalescent plasma COVID-19 Critical Dexamethasone drug drugs effective Efficacy English Etanercept etesevimab Evusheld Favipiravir fluvoxamine Golimumab help Hydroxychloroquine Imdevinab immune response Immunotherapy indication infliximab itolizumab Ivermectin Lemilumab Lopinavir Lopinavir/ritonavir Medicines metformin molnupiravir offer Pandemia pandemic Paxlovid PF-07321332 physician precocity prevented Ravulizumab Remdesivir Ritonavir ruxolitinib sarilumab SARS-CoV-2 Scientific Committee Sotrovimab Spanish the vaccine therapeutic Tixagevimab Tocilizumab Tofacitinib Treatment Vaccine virus Vitamin Vitamin D
[DOI] 10.37201/req/158.2021 PMC 바로가기 [Article Type] Review

Effectiveness and safety of Ivermectin in COVID-19 patients: A prospective study at a safety-net hospital

Observational Study

Published on 2022-04-012022-10-04
Journal: Journal of medical virology [Category] Fulltext, MERS, 임상,

[키워드] acute respiratory syndrome addition adjust Analysis benefit clinical care clinical outcomes comparison confounders control group coronavirus COVID-19 Day dose Effectiveness Efficacy group hospital Hospital stay hospitalized patient ICU ICU admission in vitro in-hospital mortality inhibit intensive care intubation rate Ivermectin ivermectin group ivermectin treatment maintain mechanical ventilation Mortality multivariable logistic regression not significantly different outcome patients with COVID-19 propensity score matching Prospective Study PSM Replication safety profile SARS-CoV-2 SARS-CoV-2 replication significantly higher treatment group was used with COVID-19
[DOI] 10.1002/jmv.27469 PMC 바로가기 [Article Type] Observational Study

An in-silico analysis of ivermectin interaction with potential SARS-CoV-2 targets and host nuclear importin α

잠재적인 SARS-CoV-2 표적 및 숙주 핵 임포틴 α와의 이버멕틴 상호작용에 대한 인-실리코 분석

Article

Published on 2022-04-012022-09-11
Journal: Journal of biomolecular structure & dynamics [Category] COVID19(2023년), SARS, 치료제,

[키워드] accounted Analysis antiparasitic Antiviral agents assist AutoDock AutoDock vina binding binding energy complex complexes COVID-19 deviation docked docking drug target drugs exhibited fluctuation Host in vitro in-silico inhibitory interacting residue Interaction Ivermectin mechanism of action moderate molecular molecular docking molecular dynamics Molecular dynamics simulation Molecular mechanics NLS non-structural protein Nsp9 nuclear nuclear localization signal Protein protein-ligand root SARS-CoV-2 SARS-CoV-2 replication surface area target targets trajectory viral infections with COVID-19
[DOI] 10.1080/07391102.2020.1841028 PMC 바로가기 [Article Type] Article

Adverse drug reactions associated with ivermectin use for COVID-19 reported in the World Health Organization’s pharmacovigilance database

Correspondence

Published on 2022-04-012022-10-05
Journal: Thérapie [Category] 치료제,

[키워드] Adverse drug reaction COVID-19 database Ivermectin pharmacovigilance reported World Health Organization
[DOI] 10.1016/j.therap.2022.03.002 [Article Type] Correspondence

A Multimodal Strategy to Reduce the Risk of Hospitalization/death in Ambulatory Patients with COVID-19

Article

Published on 2022-04-012023-07-08
Journal: Archives of medical research [Category] COVID19(2023년),

[키워드] Ambulatory management COVID-19 Ivermectin SARS-CoV-2 Telemedicine
[DOI] 10.1016/j.arcmed.2022.01.002 PMC 바로가기

From hydroxychloroquine to ivermectin: how unproven “cures” can go viral

Article

Published on 2022-04-012023-07-08
Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년),

[키워드] COVID-19 Effectiveness Hydroxychloroquine infodemic Ivermectin
[DOI] 10.1016/j.cmi.2022.01.008 PMC 바로가기

Bias as a source of inconsistency in ivermectin trials for COVID-19: A systematic review. Ivermectin’s suggested benefits are mainly based on potentially biased results

Research article

Published on 2022-04-012022-10-05
Journal: Journal of clinical epidemiology [Category] COVID19(2023년), SARS, 임상,

Could the COVID-19-Driven Increased Use of Ivermectin Lead to Incidents of Imbalanced Gut Microbiota and Dysbiosis?

COVID-19로 인해 증가된 Ivermectin 사용이 장내 미생물 불균형 및 Dysbiosis를 유발할 수 있습니까?

Review

Published on 2022-04-012022-09-11
Journal: Probiotics and antimicrobial proteins [Category] COVID19(2023년), SARS, 치료제,

[키워드] Affect animals COVID-19 diagnosed with COVID-19 drug Dysbiosis eukaryotic gut microbiota hosts humans incident Increased individual Infection Ivermectin nucleus SARS-CoV-2 SARS-COV-2 infection suggestion susceptible Treatment virus
[DOI] 10.1007/s12602-022-09925-5 PMC 바로가기 [Article Type] Review

Ivermectin administration is associated with lower gastrointestinal complications and greater ventilator-free days in ventilated patients with COVID-19: A propensity score analysis

Research article

Published on 2022-04-012022-10-05
Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), SARS, 치료제,

[키워드] 95% CI 95% confidence interval administration Admission antiparasitic drug assigned Clinical outcome Control COVID-19 COVID-19 patient COVID-19 patients diarrhea digestive Effect evaluate evaluated Gastrointestinal gastrointestinal complication Gastrointestinal symptom greater hazard ratio ICU incidence intensive care unit Ivermectin logistic regression model mechanical ventilation mechanically ventilated nasal tube Odds ratio outcome Patient prevention Probability propensity score analysis Regression model reported Result severe COVID-19 patient Symptom Ventilated ventilated patient ventilator-free day Ventilator-free days Weighting with COVID-19
[DOI] 10.1016/j.jiac.2021.12.024 [Article Type] Research article