A synthetic consensus anti–spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primatesArticle Published on 2015-09-042022-11-01 Journal: Science Translational Medicine [Category] Coronavirus, [키워드] acute respiratory syndrome antigen-specific neutralizing antibody antiviral therapy approved Arabian Peninsula cause caused cellular immunity characteristic Consensus coronavirus deaths disease DNA vaccine Europe exhibited increase in induce Infection lack Lineage macaque macaques MERS MERS coronavirus MERS spike protein MERS-CoV mice Middle East morbidity Mortality nosocomial pathogen Pneumonia Prevent protective immunity protective response Protein Radiographic respiratory syndrome coronavirus rhesus macaque route of infection SARS-CoV seroconverted syndrome The United States Transmission treat Vaccine viral challenge virus-neutralizing [DOI] 10.1126/scitranslmed.aac7462 PMC 바로가기 [Article Type] Article
Laboratory Testing for Middle East Respiratory Syndrome Coronavirus, California, USA, 2013–2014Dispatch Published on 2015-09-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, MERS, [키워드] affected California Department effort identify imported infection control investigated Laboratory testing MERS MERS coronavirus MERS-CoV Middle East Middle East respiratory syndrome Novel coronavirus positive Public respiratory respiratory syndrome coronavirus Surveillance tested Testing travel-associated USA viruses [DOI] 10.3201/eid2109.150476 PMC 바로가기 [Article Type] Dispatch
A sensitive and specific antigen detection assay for Middle East respiratory syndrome coronavirusOriginal Article Published on 2015-04-222023-05-31 Journal: Emerging Microbes & Infections [Category] MERS, 조류인플루엔자, [키워드] Antigen detection ELISA MERS coronavirus [DOI] 10.1038/emi.2015.26 PMC 바로가기 [Article Type] Original Article
The Effectiveness of Convalescent Plasma and Hyperimmune Immunoglobulin for the Treatment of Severe Acute Respiratory Infections of Viral Etiology: A Systematic Review and Exploratory Meta-analysisArticle Published on 2015-01-012023-06-14 Journal: The Journal of Infectious Diseases [Category] MERS, [키워드] convalescent plasma MERS coronavirus Meta-analysis severe acute respiratory infection systematic review [DOI] 10.1093/infdis/jiu396 PMC 바로가기
Successful recovery of MERS CoV pneumonia in a patient with acquired immunodeficiency syndrome: A case reportArticle Published on 2014-11-292022-11-01 Journal: Journal of Clinical Virology [Category] Coronavirus, [키워드] Case report cause CMV, cytomegalovirus CoV CT, Computed tomography diagnosed East ELISA, enzyme linked immunosorbent assay HIV HIV patient HIV, Human immunodeficiency virus Human immunodeficiency interferon MERS MERS coronavirus MERS CoV, Middle East Respiratory Syndrome Coronavirus middle morbidity and mortality outcome Patient PJP, pneumocystis jirovecii pneumonia Pneumonia reported respiratory ribavirin RT-PCR, Reverse transcription polymerase chain reaction severe pneumonia severity shedding TMP/SX, trimethoprim/sulfamethoxazole Treatment were used with HIV [DOI] 10.1016/j.jcv.2014.11.030 PMC 바로가기 [Article Type] Article
Receptor-binding domain-based subunit vaccines against MERS-CoVArticle Published on 2014-11-202022-11-01 Journal: Virus research [Category] Coronavirus, MERS, [키워드] animal model assist caused coronavirus develop development domain effective Effective vaccines Human MERS MERS coronavirus MERS-CoV MERS-CoV vaccines Middle East Middle East respiratory syndrome Coronavirus Pandemics Protein provide RBD Receptor-binding domain researcher Safe Spread Subunit vaccine subunit vaccines syndrome Vaccine development Vaccines [DOI] 10.1016/j.virusres.2014.11.013 PMC 바로가기 [Article Type] Article
Family Cluster of Middle East Respiratory Syndrome Coronavirus Infections, Tunisia, 2013Dispatch Published on 2014-09-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, [키워드] ARDS Diagnosis family Family cluster ICU Infection MERS coronavirus MERS-CoV Middle East Middle East respiratory syndrome PCR respiratory respiratory syndrome coronavirus respiratory tract sample reverse transcription PCR Saudi Arabia sequence serum Tunisia United Arab Emirates viruses were infected [DOI] 10.3201/eid2009.140378 PMC 바로가기 [Article Type] Dispatch
Enhanced MERS Coronavirus Surveillance of Travelers from the Middle East to EnglandDispatch Published on 2014-09-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, [키워드] acute respiratory distress acute respiratory illness coronavirus England enhanced less manifestation MERS MERS coronavirus Middle East Middle East respiratory syndrome public health surveillance Surveillance syndrome tested United Kingdom virus viruses [DOI] 10.3201/eid2009.140817 PMC 바로가기 [Article Type] Dispatch
Structural and functional characterization of MERS coronavirus papain-like proteaseResearch Published on 2014-06-042022-10-29 Journal: Journal of Biomedical Science [Category] Coronavirus, [키워드] Analysis antiviral drug antiviral target Circular Coronaviral coronavirus Coronaviruses CoV demonstrated Deubiquitination develop European country exhibit expressed Fatality rate functional functional consequence highly pathogenic indicated inhibiting Jeddah kinetic MERS coronavirus MERS-CoV Middle East monomer natural mutation organized Papain-like protease proteolytic proteolytic activity respiratory syndrome coronavirus Result SARS-CoV Saudi Arabia spread to therapy ultracentrifugation virus [DOI] 10.1186/1423-0127-21-54 PMC 바로가기 [Article Type] Research
Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi ArabiaDispatch Published on 2013-12-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, MERS, [키워드] coronavirus detect Human lentiviral MERS MERS coronavirus MERS-CoV MERS-CoV infection Middle East Middle East respiratory syndrome Coronavirus Neutralizing activity Neutralizing antibodies neutralizing antibody plasma pseudotyping respiratory infections respiratory syndrome coronavirus Saudi Arabia Seroprevalence serum spike tested viral spike protein viruses [DOI] 10.3201/eid1912.130701 PMC 바로가기 [Article Type] Dispatch