neurons
[대역어] 신경 세포
[용어속성] Term
[용어속성] Term
Evidence of central nervous system infection and neuroinvasive routes, as well as neurological involvement, in the lethality of SARS-CoV-2 infection
SARS-CoV-2 감염의 치사율에 대한 중추 신경계 감염 및 신경 침습 경로 및 신경학적 관여의 증거
Review
[키워드] absence
acute respiratory syndrome
acute respiratory syndrome coronavirus
acute respiratory syndrome coronavirus-2
Brain
cause of death
caused
Central nervous system
cerebrospinal fluid
clinical symptom
Clinical symptoms
CNS
coronavirus
coronavirus disease
Coronavirus disease 2019
Coronavirus-2
COVID-19
COVID-19 patient
COVID-19 patients
CSF
dead
death
early stage
Evidence
evidence of
global health
Gustatory
Health
higher risk
Hypothesis
in vitro
in vivo experiment
Infection
infection with SARS-CoV-2
lethality
mechanism
Mortality
nervous system
neuroinvasion
Neuroinvasive
neurological
Neurological deficit
neurological deficits
Neurological involvement
Neurological symptom
Neurological symptoms
Neuron
neurons
Neuropathology
nine
olfactory
outbreak
pathophysiology
Pathways
Patient
positive
provided
reported
SARS-CoV-2
SARS-COV-2 infection
Severe acute respiratory syndrome
severe acute respiratory syndrome Coronavirus
severe COVID-19
severe COVID-19 patients
Support
[DOI] 10.1002/jmv.26570 PMC 바로가기 [Article Type] Review
[DOI] 10.1002/jmv.26570 PMC 바로가기 [Article Type] Review
Neuroinvasion of SARS-CoV-2 in human and mouse brain
인간과 쥐의 뇌에서 SARS-CoV-2의 신경 침범
Article
[키워드] ACE2
Affect
antibody
approach
Autopsies
Autopsy
Brain
brain organoids
breath
Central nervous system
cerebrospinal fluid
changes in
CNS
Consensus
consequence
cortical
COVID-19
COVID-19 patient
detect
died
direct infection
Evidence
evidence of
feature
human ACE2
Human brain
Immune cell
in vivo
independent
infect
Infection
infections
interferon
mice
Neuroinvasive
Neuron
neuronal infection
neurons
organ system
organ systems
overexpressing
Patient
prevented
probe
respiratory
Respiratory disease
response
SARS-CoV-2
SARS-CoV-2 neuroinvasion
second
type I interferon
with infection
[DOI] 10.1084/jem.20202135 PMC 바로가기 [Article Type] Article
[DOI] 10.1084/jem.20202135 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Infection and Disease Modelling Using Stem Cell Technology and Organoids
줄기 세포 기술 및 오르가노이드를 사용한 SARS-CoV-2 감염 및 질병 모델링
Review
[키워드] ACE2
airway epithelial cells
alveolar
Apoptosis
cardiovascular system
Cell
cell damage
cells
Central nervous system
Choroid plexus
Clinical studies
clinical study
colonic
contribute
demonstrated
Direct
disease
Endothelial cell
endothelial cells
Enterocyte
enterocytes
epithelial
epithelial cells
gastrointestinal tract
highlighting
human host
Hypothesis
immunological
impairing
in vitro model
indirect effect
indirect effects
infect
infected individuals
Inflammation
innate immune response
intestinal organoid
lung
lung alveolar
lung epithelia
mechanism
Neurological symptom
Neurological symptoms
Neuron
neurons
Organoid
organoids
organs
Pathogenesis
pathogenesis of SARS-CoV-2
replicate
review
SARS-CoV-2
SARS-CoV-2 cell
SARS-COV-2 infection
SARS-CoV-2 pathogenesis
STEM
stem cell
surfactant
susceptible
systemic inflammatory
target
technology
Trigger
triggers
tropism
type I
variance
Vascular damage
Viral
viral damage
viral infection
virus
[DOI] 10.3390/ijms22052356 PMC 바로가기 [Article Type] Review
[DOI] 10.3390/ijms22052356 PMC 바로가기 [Article Type] Review
Nicotinic Acetylcholine Receptor Involvement in Inflammatory Bowel Disease and Interactions with Gut Microbiota
Review
[키워드] α7 and α9 nicotinic receptor subtypes
Acetylcholine
activity
autonomic
Brain
Central nervous system
Cholinergic anti-inflammatory pathway
commensal bacteria
complex interplay
COVID-19
Critical
cytokine release
Dysbiosis
dysregulation
expression
ganglia
gastrointestinal tract
Gut
gut microbiome
Gut-brain axis
immune
Immune cell
immune cells
Inflammatory bowel disease
inflammatory bowel diseases
information
Involvement
local control
Microbiome
modulation
nervous system
Neuron
neurons
Nicotinic acetylcholine receptors
organ
pathogenic strain
postganglionic
provided
receptor
receptors
sensory neuron
synaptic
toxins
Transmission
[DOI] 10.3390/ijerph18031189 PMC 바로가기 [Article Type] Review
[DOI] 10.3390/ijerph18031189 PMC 바로가기 [Article Type] Review
Human iPSC-Based Modeling of Central Nerve System Disorders for Drug Discovery
Review
[키워드] Alzheimer’s disease
animal models
appear
approach
astrocytes
Cell
cell type
Clinical efficacy
clinical trials
CNS
CNS disease modeling
contribute
COVID-19
Culture
disease
disease pathogenesis
drug
Drug discovery
exhibiting
Human
identify
in vitro
induced pluripotent stem cells (iPSC)
Interaction
limitation
modeling
nerve
neurons
pathology
Patient
physiological
platform
Precision
provide
responses
System
therapeutic
Therapeutic strategies
three-dimensional cerebral organoids
tissue
toxicity screening
translation
two-dimensional
[DOI] 10.3390/ijms22031203 PMC 바로가기 [Article Type] Review
[DOI] 10.3390/ijms22031203 PMC 바로가기 [Article Type] Review
The Spatial and Cell-Type Distribution of SARS-CoV-2 Receptor ACE2 in the Human and Mouse Brains
Neurology
[키워드] ACE2
ACE2 expression
acute respiratory syndrome
Affect
angiotensin-converting enzyme 2
astrocytes
Brain
Brain infection
brains
Cell
Central nervous system
coronavirus
coronavirus disease
COVID-19
dataset
distribution
distribution analysis
Effect
Endothelial cell
endothelial cells
excitatory
expressed
expression
host cell
Human
indicate
inhibitory
investigated
middle temporal gyrus
mouse
mouse model
neurological
Neuron
neurons
nuclear
nuclei
olfactory
organs
pathogenic
patients
pericyte
posterior cingulate cortex
Potential
SARS-coronavirus 2
SARS-CoV-2
SARS-COV-2 infection
Symptom
Transcriptome
[DOI] 10.3389/fneur.2020.573095 PMC 바로가기 [Article Type] Neurology
[DOI] 10.3389/fneur.2020.573095 PMC 바로가기 [Article Type] Neurology
Cognitive impact of COVID-19: looking beyond the short term
Review
[키워드] accelerate
accumulating
ACE inhibitor
ACE-2
acute illness
angiotensin receptor blocker
Angiotensin receptor blockers
Angiotensin-converting enzyme
angiotensin-converting enzyme inhibitors
angiotensin-converting enzyme-2
ApoE
cardiorespiratory
Central nervous system
cerebral
classical
CNS
Cognitive function
Cognitive impairment
COVID-19
COVID-19 patient
current
Dementia
deplete
develop
disease
Disseminated intravascular coagulation
dysfunction
Endothelial cell
endothelial cells
Evidence
exacerbate
exacerbating
expression
Follow-up
hospitalised patient
immune activation
increased risk
individuals
infecting
Inflammation
inflammatory effect
Lewy body
Limited
lowest
medication
Meta-analysis
nasal mucosa
Neurological complication
neurons
olfactory
pathology
Patient
pericyte
pericytes
Phosphorylation
predicted
Protective
RAS
recent
receptor
reducing
Respiratory disease
Respiratory function
risk
SARS-CoV-2
SARS-CoV-2 entry
SARS-CoV-2 virus
Spread
stroke
suggested
Survivors
target
therapy
thrombosis
vascular leakage
vasculature
virus
White matter ischaemia
[DOI] 10.1186/s13195-020-00744-w PMC 바로가기 [Article Type] Review
[DOI] 10.1186/s13195-020-00744-w PMC 바로가기 [Article Type] Review
Molecular Mechanisms of Proteins — Targets for SARS-CoV-2 (Review)
단백질의 분자 메커니즘 — SARS-CoV-2의 표적(검토)
Review
[키워드] accumulating
ACE2
Activation
Affect
affected
angiotensin
Angiotensin 1-7
Angiotensin II
Angiotensin-converting enzyme
angiotensin-converting enzyme 2
astrogliosis
basal ganglia
blood-brain barrier
Brain
brain damage
brain damage in COVID-19
brain tissue
breakdown
caused
CD147
Central nervous system
Cerebellum
change
CNS
coronavirus
Coronavirus infection
COVID-19
Cytokines
damage
death
develop
disease
Diseases
driven by
Endothelial cell
endothelial cells
enzyme
Evidence
exposure to
expressed
Extracellular matrix
functional
ganglia
help
hypothalamus
inducer
Infection
information
interactions
leads
leukocyte
leukocytes
Local
massive
matrix metalloproteinases
mechanisms
membrane permeability
metabolism
microglia
midbrain
molecular mechanism
molecular mechanisms
moment
nasal epithelium
Neuroinflammation
neurons
Neurovascular
New coronavirus
new coronavirus SARS-CoV-2
pathogen
Pathogenesis
pathogenesis of COVID-19
Piriform cortex
Proinflammatory cytokine
proinflammatory cytokines
pulmonary symptoms
Research
review
SARS-CoV-2
Serine
serine protease
serine protease TMPRSS2
substantia
substantia nigra
target
target proteins
the disease
TMPRSS2
Treatment
Vascular
Via
virus
virus spread
[DOI] 10.17691/stm2020.12.6.11 PMC 바로가기 [Article Type] Review
[DOI] 10.17691/stm2020.12.6.11 PMC 바로가기 [Article Type] Review