Neutralizing activity to SARS-CoV-2 in 1.2 to 10.0 month convalescent plasma samples of COVID-19: A transversal surrogate in vitro study performed in Quito-EcuadorCOVID-19의 1.2~10.0개월 회복기 혈장 샘플에서 SARS-CoV-2에 대한 중화 활성: 키토-에콰도르에서 수행된 횡단 대리 시험관내 연구Article Published on 2022-09-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition analyzed binding domain BSL2 facility BSL3 caused convalescence Convalescent patients convalescent plasma convalescent sera coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 determine diagnostic methods Ecuador glycoprotein IgG IgM Immunoglobulin Immunoglobulin G immunoglobulin M in some in vitro study Infection NAb NAbs neutralization test Neutralizing Neutralizing activity Neutralizing antibodies neutralizing antibody performed plasma positive presence or absence Quito remained reported respiratory SARS-CoV-2 Seroconversion severe acute respiratory syndrome Coronavirus surrogate Test the SARS-CoV-2 Viral viral spike virus Wuhan Wuhan, China [DOI] 10.1002/jmv.27866 PMC 바로가기 [Article Type] Article
Preserved recognition of Omicron spike following COVID-19 messenger RNA vaccination in pregnancy임신 중 COVID-19 메신저 RNA 백신 접종 후 오미크론 스파이크의 보존된 인식Article Published on 2022-09-012022-09-11 Journal: American journal of obstetrics and gynecology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] administration analyzed antibodies antibody attenuate binding center Complete Control COVID-19 COVID-19 vaccine COVID-19 vaccines disease disease control disease course disease severity during pregnancy Efficacy Evolution of SARS-CoV-2 Fc receptor Fc receptors Fcγ receptor full dose regimen Immunoglobulin immunoglobulin M Infection Luminex assay Messenger RNA Moderna mRNA mRNA vaccine mRNA-1273 neutralization Neutralizing activity Neutralizing antibodies obstetrics omicron Omicron variant organization Pfizer/BioNTech Pregnancy pregnant women preserved prevention PROTECT raised receiving receptor Receptor binding Receptor binding domain reduce reduced remained SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variants severe disease Spike-specific antibody These data vaccinated individuals vaccination Vaccine vaccine efficacy vaccine-induced antibodies vaccine-induced antibody Vaccine-induced immunity variant variants variants of concern [DOI] 10.1016/j.ajog.2022.04.009 PMC 바로가기 [Article Type] Article
Reduced Immune Response and Neutralizing Antibody Activity to the SARS-CoV-2 Vaccination in Patients with a History of Solid Organ TransplantArticle Published on 2022-09-012022-11-15 Journal: Laboratory medicine [Category] SARS, 변종, 진단, 치료기술, [키워드] activity Allogeneic antibodies antibody booster Cell Control controls COVID-19 healthcare worker history immune immune response in vitro monoclonal mounted Neutralizing activity neutralizing antibody nucleocapsid organ Patient patients plasma positive produced reduced Remnant response Sample SARS-CoV-2 SARS-CoV-2 IgG SARS-COV-2 infection SARS-CoV-2 vaccination Solid solid organ solid organ transplant Spike protein the antibody the SARS-CoV-2 Transplant vaccination variant virus was obtained wild type [DOI] 10.1093/labmed/lmac038 PMC 바로가기
Effectiveness of the third dose of BNT162b2 vaccine on neutralizing Omicron variant in the Japanese population일본 인구에서 오미크론 변이체 중화에 대한 BNT162b2 백신 3차 접종의 효과Article Published on 2022-09-012022-09-11 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] acquired immunity Anti-receptor binding domain antibody anti-SARS-CoV-2 antibody binding domain BNT162b2 BNT162b2 vaccine booster booster vaccination collected contribute COVID-19 case COVID-19 cases declines Delta dose Efficacy elevated evaluated event fatigue Fever healthcare worker Healthcare workers humoral Humoral immunity Immunity individual Japanese Local local swelling median myalgia neutralization Neutralizing Neutralizing activity neutralizing antibody of BNT162b2 omicron Omicron variant Pfizer promotion provide Pseudotyped viruses Questionnaires reduced SARS-CoV-2 second dose sera serum sample serum samples Side effect Side effects significantly swelling Toyama U/mL university vaccination Vaccine variant variants was measured Waves wild-type [DOI] 10.1016/j.jiac.2022.05.009 PMC 바로가기 [Article Type] Article
Activation of SARS-CoV-2 neutralizing antibody is slower than elevation of spike-specific IgG, IgM, and nucleocapsid-specific IgG antibodiesArticle Published on 2022-09-012022-11-15 Journal: Scientific Reports [Category] SARS, 진단, 치료기술, [키워드] Abbott anti-nucleocapsid antibody anti-Nucleocapsid IgG anti-S Anti-spike antibody Antibody testing Antibody titer assays chemiluminescent immunoassay correlated COVID-19 diagnostic domain facilitate humoral immune response IgG IgG antibody IgM investigated laboratory measurement marker Neutralization assay Neutralizing Neutralizing activity Prophylactic Quantitative quantitative measurement response SARS-CoV-2 infected patients SARS-COV-2 infection SARS-CoV-2 neutralizing antibody serological serological response Severe case specific antibodies spike-specific IgG the SARS-CoV-2 therapeutic Virus neutralization were measured [DOI] 10.1038/s41598-022-19073-z PMC 바로가기
Lasting SARS-CoV-2 specific IgG Antibody response in health care workers from Venezuela, 6 months after vaccination with Sputnik VArticle Published on 2022-09-012022-11-15 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 진단, [키워드] antibody antibody unit average Binding antibody units or BAU/ml Cohort COVID-19 COVID-19 infection ELISA enrolled evaluated geometric mean concentration GMC Health care worker hospital Humoral immunity hybrid Hybrid COVID-19 immunity IgG IgG antibodies IgG antibody IgG level in vitro infection with SARS-CoV-2 information international unit International units or IU/ml naïve naïve subjects Neutralizing activity nucleocapsid protein (NP) Protein provided RBD RBD binding RBD binding inhibition assay receiving receptor binding domain (RBD) SARS-CoV-2 second dose Sputnik V vaccine subject vaccination Vaccine Venezuela were expressed were measured wild-type [DOI] 10.1016/j.ijid.2022.06.008 PMC 바로가기
Antibody Avidity and Neutralizing Response against SARS-CoV-2 Omicron Variant after Infection or VaccinationArticle Published on 2022-08-312022-11-15 Journal: Journal of Immunology Research [Category] SARS, 변종, 진단, [키워드] adenovirus-based antibody Antibody avidity avidity bind binding binding antibody cellular receptor collected cross-protection domain dose elicited epitope exhibit Heterologous high affinity Immunity increase mRNA vaccine Mutation natural infection Neutralizing Neutralizing activity Neutralizing antibodies neutralizing antibody Neutralizing titer omicron pandemic patients Protective antibody RBD RBD-binding IgG remained response Sample SARS-CoV-2 SARS-CoV-2 infected patient SARS-CoV-2 spike protein subject tested the RBD the spike protein vaccination Vaccine vaccine dose vaccinees Vaccines variant virus wild-type wild-type SARS-CoV-2 wild-type virus [DOI] 10.1155/2022/4813199 PMC 바로가기
Third Early “Booster” Dose Strategy in France of bnt162b2 SARS-CoV-2 Vaccine in Allogeneic Hematopoietic Stem Cell Transplant Recipients Enhances Neutralizing Antibody ResponsesArticle Published on 2022-08-302022-11-15 Journal: Viruses [Category] SARS, 변종, 진단, [키워드] administration allogeneic HSCT Anti-spike antibody Antibody Response Beta BNT162b2 vaccine booster Breakthrough infection can be used circulation correlated COVID-19 COVID-19 vaccine Delta delta variant dose enzyme France healthy hematopoietic high-risk population HSCT HSCT immunocompromised patients HSCT recipient humoral Humoral response immune immune protection Immune suppression immunoassay Immunocompromised immunocompromised individuals Immunocompromised patients Immunosuppressed individual marker monoclonal antibody Neutralization assay neutralization titer Neutralizing Neutralizing activity neutralizing antibody Neutralizing antibody response omicron preventive measure PROTECT Protein question raised recipient recipients response SARS-CoV-2 SARS-CoV-2 variant sensitivity significantly lower STEM Strategy Support tested the vaccine Transplant vaccination vaccine dose variant variant of concern variants [DOI] 10.3390/v14091928 PMC 바로가기
Antibody and Memory B-Cell Immunity in a Heterogeneously SARS-CoV-2-Infected and -Vaccinated PopulationArticle Published on 2022-08-302022-11-15 Journal: mBio [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] accumulating acute respiratory syndrome Adenovirus antibody B-cell B.1.1.529 Combination coronavirus correlated country determine distribution elicited FIVE help heterogeneous immune immune evasion immune response Immunity individuals Infection less Level majority memory B memory B cells memory B-cell mRNA Neutralizing Neutralizing activity Neutralizing antibodies neutralizing antibody titers Omicron variant platform Population population immunity prefusion recipient SARS-CoV SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant single vaccine spike trimer the vaccine undetectable vaccination Vaccine [DOI] 10.1128/mbio.00840-22 PMC 바로가기
A Bispecific Antibody Targeting RBD and S2 Potently Neutralizes SARS-CoV-2 Omicron and Other Variants of ConcernRBD 및 S2를 표적으로 하는 이중특이성 항체는 SARS-CoV-2 오미크론 및 우려되는 기타 변이체를 잠재적으로 중화합니다Article Published on 2022-08-242022-09-11 Journal: Journal of Virology [Category] SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Alpha antibodies antibody B.1.1.7 B.1.351 B.1.617.1 B.1.617.2 Beta binding bispecific antibodies breadth Breakthrough infection caused concern contagious coronavirus country COVID-19 COVID-19 vaccines Delta demonstrated domain dominant effective Efficacy epitope Epitopes feasible highlighting IMPROVE mAbs monoclonal antibody Mutation neutralization neutralize Neutralizing Neutralizing activity Neutralizing antibodies neutralizing antibody omicron Omicron variant Omicron variants Other other variant other variants parental Prevent Pseudotyped virus RBD Receptor-binding domain reduced respiratory retained SARS-CoV-2 SARS-CoV-2 RBD SARS-CoV-2 variants SARS-CoV-2 WT specificity Spike protein target targeting tested the spike protein therapeutic treat Vaccine variant variants variants of concern VoC VOCs wild-type [DOI] 10.1128/jvi.00775-22 PMC 바로가기 [Article Type] Article