Isolation and characterization of porcine epidemic diarrhea virus associated with the 2014 disease outbreak in Mexico: case reportResearch Article Published on 2016-06-292022-10-28 Journal: BMC veterinary research [Category] Coronavirus, [키워드] acute infection amplification Analysis Case report caused characterization characterized clinical sample Clinical sign Clinical signs Culture Cytopathic effect disease epidemic diarrhea histological homology identify initial interest isolate Isolation lesion Mexico Microscopy molecular Mortality mortality rate necropsy nucleotide sequence observation outbreak PEDV Porcine epidemic diarrhea virus Protein Result RT-PCR S glycoprotein Sequencing staining state TCID the United State trypsin USA Vero Cell Virological virus virus particle was determined was performed [DOI] 10.1186/s12917-016-0763-z PMC 바로가기 [Article Type] Research Article
Epidemic strain YC2014 of porcine epidemic diarrhea virus could provide piglets against homologous challengeResearch Published on 2016-04-222022-10-28 Journal: Virology Journal [Category] Coronavirus, MERS, [키워드] acute diarrhea aligned Amino acid Analysis antigenic antigenicity caused China classical colostrum Complete control vaccine Critical demonstrated diarrhea effective Efficiency Epidemic epidemic diarrhea Epidemic strain Evidence genomic sequence homologous identity immune Immune protective efficiency immunized inactivated indicate insertion intestinal isolate Isolation neutralizing antibody Neutralizing antibody titer nucleotide nucleotide deletion nucleotide sequence occurred outbreak pathogenic PEDV Porcine epidemic diarrhea virus PROTECT Protective Result S gene sequence sera significantly higher Strains Symptom Vaccine variants Variation virulent virus [DOI] 10.1186/s12985-016-0529-z PMC 바로가기 [Article Type] Research
Suppression subtractive hybridization method for the identification of a new strain of murine hepatitis virus from xenografted SCID miceOriginal Article Published on 2015-09-082022-10-28 Journal: Archives of Virology [Category] Coronavirus, MERS, [키워드] absence association clone combined immunodeficiency comparison coronavirus determinant Driver cDNA Frame genome sequence genomic sequence Hepatitis identify Langerhans cell histiocytosis liver mice murine murine hepatitis virus new strain new virus nucleotide sequence PCR predicted Protein protein level retroviral retrovirus SCID Mouse sequence sequenced Subtract cDNA Library suppression Suppression Subtractive Hybridization Tester cDNA tissues unique virulent virus virus strain was used whole genome [DOI] 10.1007/s00705-015-2592-y PMC 바로가기 [Article Type] Original Article
Phylogenetic analysis of avian infectious bronchitis virus S1 glycoprotein regions reveals emergence of a new genotype in Moroccan broiler chicken flocksResearch Published on 2015-08-042022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] aligned amino acid sequence amino-acid amino-acid change amplified analyses Analysis bronchitis circulating Clustering gene sequence Genotype glycoprotein IBV identity indicated Infectious Bronchitis Virus isolate isolates Italy modify Morocco mutant New genotype nucleotide sequence Partial partial sequence pathogen Phylogenetic Phylogenetic analysis Protein protein sequence ranged reached Region Result reveal RT-PCR sequenced Sequencing similarity Spain strain the S1 subunit Vaccination strategy Vaccines virus wild-type [DOI] 10.1186/s12985-015-0347-8 PMC 바로가기 [Article Type] Research
Detection and Molecular Diversity of Spike Gene of Porcine Epidemic Diarrhea Virus in ChinaArticle Published on 2013-10-222022-10-28 Journal: Viruses [Category] Coronavirus, MERS, [키워드] amino acids sequence Analysis caused China Chinese classical detection detection rate Diversity epidemic diarrhea full-length S Gene Genetic variation Hainan heterogeneity high mortality homology indicated insertion morbidity MOST Neonatal nucleotide deletion nucleotide sequence PEDV Phylogenetic analysis positive predominant regions RT-PCR S gene sequenced spike strain variant variants virus [DOI] 10.3390/v5102601 PMC 바로가기 [Article Type] Article
Sequence and phylogenetic analysis of nucleocapsid genes of porcine epidemic diarrhea virus (PEDV) strains in ChinaOriginal Article Published on 2013-02-072022-10-28 Journal: Archives of Virology [Category] Coronavirus, MERS, [키워드] acute diarrhea addition amino acid sequence amplified Analysis cause China Chinese cloned Cluster compared composed conserved early diagnosis epidemic diarrhea GenBank high mortality rate identity increasingly Korean less N gene nucleocapsid Nucleocapsid gene nucleotide nucleotide sequence PEDV peptide Phylogenetic analysis Protein RT-PCR selected sequence identity sequenced strain Strains the vaccine Vaccine development virus [DOI] 10.1007/s00705-012-1592-4 PMC 바로가기 [Article Type] Original Article
Genetic Diversity of Spike, 3a, 3b and E Genes of Infectious Bronchitis Viruses and Emergence of New Recombinants in KoreaArticle Published on 2013-01-312022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] Analysis Cluster Clustering coding region conducted determined Diversity E gene emergence FIVE Gene genetic diversity Genotype genotypes IBV Infectious Bronchitis Virus Infectious bronchitis virus (IBV) information insertion isolate mass Molecular epidemiology New not found nucleotide nucleotide sequence Phylogenetic Phylogenetic analysis Phylogenetic tree prevalent recombinant recombinants Recombination S gene sequence similarity spike Vaccine virus viruses [DOI] 10.3390/v5020550 PMC 바로가기 [Article Type] Article
Isolation and characterization of a variant porcine epidemic diarrhea virus in ChinaResearch Published on 2012-09-122022-10-28 Journal: Virology Journal [Category] Coronavirus, MERS, [키워드] amino acid sequence Analysis case characterized China Chinese Cluster Complete cultures Cytopathic effect determine diarrhea epidemic diarrhea Gene Genes Genome Guangdong identity immunofluorescence indicated intestine isolate Microscopy morbidity Mortality nucleotide nucleotide sequence ORF3 outbreak pathogenicity PEDV Porcine epidemic diarrhea virus reported required sequenced shown South Strains susceptible cell the spike protein variant Vero Cell virus virus isolate vomiting watery whole genome [DOI] 10.1186/1743-422X-9-195 PMC 바로가기 [Article Type] Research
SARS Coronavirus nsp1 Protein Induces Template-Dependent Endonucleolytic Cleavage of mRNAs: Viral mRNAs Are Resistant to nsp1-Induced RNA CleavageResearch Article Published on 2011-12-082022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, [키워드] 40S accelerated accompany acute respiratory syndrome Antiviral Author bind binding block cells characterized circumvent classical cleavage cleavage sites coronavirus cricket paralysis viruses Degradation demonstrated different element elements events exhibited facilitate Fever found function Hepatitis Host host gene expression host genes host mRNA host protein in vitro induce infected cells Infection inhibitor leader sequence Modification mRNA mRNAs nucleotide nucleotide sequence Protein protein synthesis recognize reporter Resistant ribosome RNA RNA modification SARS Coronavirus SARS infection severe severe symptom subunit suppress the expression susceptible translation type I type I interferon unique viral mRNA Viral protein virus virus replication [DOI] 10.1371/journal.ppat.1002433 PMC 바로가기 [Article Type] Research Article
Descriptive distribution and phylogenetic analysis of feline infectious peritonitis virus isolates of MalaysiaBrief Communication Published on 2010-01-062022-10-28 Journal: Acta Veterinaria Scandinavica [Category] Coronavirus, [키워드] age amplified product Cluster Clusters compared conserved coronavirus determined distribution fluid Genetic genetic information Genome homology included infectious isolate Malaysia male mutations nine nucleotide sequence Phylogenetic analysis Phylogenetic tree Phylogeny polymerase chain positive provided reverse transcription RT-PCR selected sequence Strains UTR virus isolate [DOI] 10.1186/1751-0147-52-1 PMC 바로가기 [Article Type] Brief Communication