pathologic – Page 6 – Communicable Diseases Research

Strategies for targeting senescent cells in human disease

Reviews

Published on 2021-10-122022-10-05
Journal: Nature Aging [Category] 신약개발,

Liver Histopathological Analysis of 24 Postmortem Findings of Patients With COVID-19 in China

Medicine

Published on 2021-10-112022-10-31
Journal: Frontiers in Medicine [Category] COVID-19,

Digital pathology and artificial intelligence in translational medicine and clinical practice

Review Article

Published on 2021-10-052022-10-04
Journal: Modern pathology : an official journal of the Unit [Category] 바이오마커,

Commonalities Between ARDS, Pulmonary Fibrosis and COVID-19: The Potential of Autotaxin as a Therapeutic Target

ARDS, 폐 섬유증 및 COVID-19 사이의 공통점: 치료 표적으로서의 Autotaxin의 가능성

Review

Published on 2021-10-042022-09-12
Journal: Frontiers in Immunology [Category] MERS, SARS, 진단,

Safety, Virologic Efficacy, and Pharmacokinetics of CT-P59, a Neutralizing Monoclonal Antibody Against SARS-CoV-2 Spike Receptor-Binding Protein: Two Randomized, Placebo-Controlled, Phase I Studies in Healthy Individuals and Patients With Mild SARS-CoV-2 Infection

SARS-CoV-2 스파이크 수용체 결합 단백질에 대한 중화 단일클론항체 CT-P59의 안전성, 바이러스학적 효능 및 약동학: 건강한 개인 및 경증 SARS-CoV-2 환자를 대상으로 한 무작위, 위약 대조, 1상 연구 2건 전염병

Randomized Controlled Trial

Published on 2021-10-012022-09-12
Journal: Clinical therapeutics [Category] MERS, SARS, 임상, 진단,

[키워드] Adverse adverse event AEs Against antibody Antiviral C-reactive protein cellular entry Clinical efficacy Cohort Common Terminology Criteria COVID-19 CT-P59 dose double-blind elevated end point enrolled examined exhibited headache healthy in healthy individual individual mild SARS-CoV-2 infection monoclonal monoclonal antibody Neutralizing neutralizing monoclonal antibody pathologic Patient pharmacokinetic pharmacokinetics phase Placebo placebo-controlled Pyrexia Randomized receive receiving reduce reductions in regdanvimab reported Safety safety profile SARS-CoV-2 secondary single ascending dose spike Time to recovery Tolerability viral titer
[DOI] 10.1016/j.clinthera.2021.08.009 PMC 바로가기 [Article Type] Randomized Controlled Trial

Clinical applications of thrombopoietin silencing: A possible therapeutic role in COVID-19?

Review article

Published on 2021-10-012022-10-05
Journal: Cytokine [Category] SARS, 변종,

[키워드] affected clinical Coronavirus 2019 COVID-19 decrease indicate Inflammation inflammatory disorder megakaryocytes Novel coronavirus offer pathologic pathology Patient patients Platelet shown therapeutic Thromboinflammation Thrombopoietin Thrombopoietin silencing thrombosis TPO Treatment turn
[DOI] 10.1016/j.cyto.2021.155634 [Article Type] Review article

Differential Impact of COVID-19 on Cancer Diagnostic Services Based on Body Regions: A Public Facility-Based Study in Hong Kong

Research article

Published on 2021-10-012022-10-05
Journal: International journal of radiation oncology, biolo [Category] 진단,

Prenatal inflammation exposure-programmed hypertension exhibits multi-generational inheritance via disrupting DNA methylome

Research

Published on 2021-09-302022-10-05
Journal: Acta pharmacologica Sinica [Category] 바이오마커,

Immune Responses against SARS-CoV-2—Questions and Experiences

Review

Published on 2021-09-282022-10-28
Journal: Biomedicines [Category] COVID-19,

[키워드] antibody approach Autoimmunity Cell cellular immunity Central nervous system Clinical management clinical manifestations Clinical symptoms complex COVID COVID-19 COVID-19 pandemic Cytokine storms develop development of the COVID-19 pandemic disease disorders effective experience fatigue immune immune response immune responses Immune status Immunity IMPROVE Inflammation knowledge memory T mRNA naturally acquired immunity neutralizing antibody Other pandemic pathologic Preliminary data question reactivity recognize Respiratory failure response SARS-CoV-2 sick Side effect syndrome systemic symptoms T and B cell responses T cell tissue understanding vaccination Vaccine virus
[DOI] 10.3390/biomedicines9101342 PMC 바로가기 [Article Type] Review

Coronavirus induces diabetic macrophage-mediated inflammation via SETDB2

420

Published on 2021-09-212022-10-29
Journal: Proceedings of the National Academy of Sciences of [Category] COVID-19, SARS,

[키워드] “cytokine storm” acute respiratory syndrome administration affected binding site blockade contribute coronavirus Coronavirus infection COVID-19 COVID-19 pandemic Cytokine storm decrease develop diabetes Diabetic diabetic patient enzyme epigenetics expression Hepatitis Hyperinflammatory IFNβ increase in induce Infection Inflammation Inflammatory inflammatory cytokine production Inflammatory cytokines Inflammatory response innate immune cell interferon beta lysine mechanism methyltransferase MHV-A59 mice monocyte monocyte/macrophage morbidity and mortality murine murine model NFkB obesity pathologic pathway Patient patients with comorbidities potential mechanism promote promoters regulate regulated responsible reverse inflammation reversed robust SARS-CoV-2 sera SETDB2 severe COVID-19 shown Signaling Significance T2D the cytokine storm therapeutic targeting Transcription type 2 diabete type 2 diabetes with COVID-19
[DOI] 10.1073/pnas.2101071118 PMC 바로가기 [Article Type] 420