Asunaprevir, a Potent Hepatitis C Virus Protease Inhibitor, Blocks SARS-CoV-2 Propagation
강력한 C형 간염 바이러스 프로테아제 억제제인 Asunaprevir, SARS-CoV-2 전파 차단
Article
[키워드] acute respiratory syndrome
acute respiratory syndrome coronavirus
acute respiratory syndrome coronavirus 2
antiviral activity
asunaprevir
binding
block
blocked
calu-3 cells
candidate
coronavirus
coronavirus disease
Coronavirus disease 2019
COVID-19
Cytopathic effect
cytopathic effects
daclatasvir
direct-acting antiviral
Drug repurposing
evaluated
Health
hepatitis C
hepatitis C virus
human lung
human lung Calu-3 cells
include
infected cells
inhibited
inhibitor
life cycle
NS5A
pandemic
potent
Propagation
Protease inhibitor
protein level
protein levels
RNA
RNA polymerase inhibitor
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV-2 propagation
SARS-CoV-2 vaccine
SARS-CoV-2-infected cells
severe acute respiratory syndrome Coronavirus
significantly
sofosbuvir
therapeutic agent
Treatment
vaccination
Vero E6
VERO E6 cells
viral life cycle
virion
[DOI] 10.14348/molcells.2021.0076 PMC 바로가기 [Article Type] Article
[DOI] 10.14348/molcells.2021.0076 PMC 바로가기 [Article Type] Article