powerful tool

[키워드] accelerated activate acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alleviate anti-influenza drug Anti-SARS-CoV-2 Activity antiviral drug ATR-002 block cascade caused Cell Cell culture cell line cell lines clinical trial clinical trials coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 progression cultures Cytokines death Disease progression Drug evaluation early infection epithelial epithelial cell evaluated expression fibrosarcoma high-risk patient High-risk patients hyperinflammation impair Infection inhibitor kinase kinases knockdown limit medication MEK1/2-inhibitor mitogen mitogen-activated protein kinase Novel coronavirus observé pandemic pandemic spread pathway powerful tool Prevent pro-inflammatory pro-inflammatory cytokines Protein Raf/MEK/ERK respiratory response Safe SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 propagation selective severe acute respiratory syndrome Coronavirus Signaling specific inhibitor Spread supplementary material Symptom target therapeutic intervention Treatment upstream vaccination virus replication while
[DOI] 10.1007/s00018-021-04085-1 PMC 바로가기 [Article Type] Original Article