New Insights on the Mediating Role of Emotional Intelligence and Social Support on University Students’ Mental Health during COVID-19 Pandemic: Gender MattersArticle Published on 2021-12-082022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] Administered caused change Characteristics COVID-19 COVID-19 pandemic emotional emotional intelligence Gender Gender differences implication indirect effect influences on insight intelligence lockdown matter Mediating mediation model mental health multiple study New opposite Portugal protective factor protective role Psychological Psychological intervention questionnaire role Significant social isolation Social support Support Symptoms university university students [DOI] 10.3390/ijerph182412935 PMC 바로가기 [Article Type] Article
A review on protective roles and potential mechanisms of metformin in diabetic patients diagnosed with COVID-19Research article Published on 2021-12-012022-10-05 Journal: Metabolism Open [Category] 신약개발, [키워드] ACE2 activities acute respiratory syndrome Alter Anti-inflammatory antidiabetic drug antioxidant Antiviral blood glucose Cardiopulmonary caused chronic inflammation coronavirus COVID-19 COVID-19 patients COVID‐19 database detrimental effect diabetes Diabetes Mellitus diabetic patient diagnosed with COVID-19 disease severity Elsevier English globe Google Scholar gut microbiota Healthcare system immunomodulatory immunomodulatory activity include infected patients investigated maintaining mechanism medication metformin molecular mechanism novel coronavirus disease potential mechanism protective role Protein public health reduced reduction in mortality risk factor SARS‐CoV‐2 searched survival Treatment Vascular viral entry virus Web of Science with COVID-19 [DOI] 10.1016/j.metop.2021.100137 [Article Type] Research article
Niclosamide for Covid-19: bridging the gapCovid-19용 니클로사미드: 격차 해소Review Published on 2021-12-012022-09-11 Journal: Molecular biology reports [Category] SARS, 치료제, [키워드] acute respiratory distress syndrome angiotensin Angiotensin-converting enzyme anthelminthic Anti-inflammatory anti-inflammatory effect Anti-inflammatory effects anti-SARS-CoV-2 Antiviral antiviral activities Antiviral effect antiviral effects biological processes clinical outcomes clinical study clinical trial clinical trials Concentration concerning COVID-19 COVID-19 severity Cytokines Cytopathic effect Direct disease distress Effect endosomal pH enzyme Google Scholar homeostasis immune in vivo Inflammasome inflammatory signaling inhibit interruption mandatory maturation mechanism modulate modulating mTOR mTOR signaling NCL neutralization NF-κB niclosamide NLRP3 NLRP3 inflammasome oral bioavailability oxidative phosphorylation pandemic pathway Patient pleiotropic pro-inflammatory cytokines Prospective protective role reduce reducing Regulatory respiratory distress Respiratory distress syndrome SARS-CoV-2 SARS-COV-2 infection Science Science Direct serum severity signaling pathway suppression therapeutic therapy treat viral proliferation Viral protein was done Web of Science [DOI] 10.1007/s11033-021-06770-7 PMC 바로가기 [Article Type] Review
Association of lockdowns with the protective role of ultraviolet-B (UVB) radiation in reducing COVID-19 deathsArticle Published on 2021-11-242022-10-04 Journal: Scientific Reports [Category] MERS, SARS, 유전자 메커니즘, [키워드] Applied immunology association average clinical study confounding factors country COVID-19 COVID-19 pandemic cumulative dataset death deaths Diseases endocrinology Evidence example Factors growth growth rate Health care Health occupations increase increase in indicate Infection Infectious diseases Innate immune cells Innate immunity Intervention limit lockdown lockdowns measure Measures Medical research Mortality nation New York City Pathogenesis Protective protective role Radiation reduced reducing reduction in risk severity Spread spread of COVID-19 Support ultraviolet while widespread [DOI] 10.1038/s41598-021-01908-w PMC 바로가기 [Article Type] Article
Antibodies specific to SARS-CoV-2 proteins N, S and E in COVID-19 patients in the normal population and in historical samples정상 인구 및 과거 샘플의 COVID-19 환자에서 SARS-CoV-2 단백질 N, S 및 E에 특이적인 항체Animal Published on 2021-11-242022-09-10 Journal: The Journal of General Virology [Category] MERS, SARS, 진단, 치료법, [키워드] acquired immunity acute respiratory syndrome acute respiratory syndrome coronavirus analysed antibodies antibody Antibody Response can not circulation coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient diagnostic domain envelope protein epidemiological healthy IgA IgA levels IgG IgG level immune response immune responses immunology Infection inhibit SARS-CoV-2 Kinetics nucleocapsid protein other coronavirus other coronaviruses pandemic Patient preserved Protective protective role Recognition respiratory SARS-CoV-2 SARS-CoV-2 protein sera severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spike protein Spread target the SARS-CoV-2 Treatment virus virus-neutralizing [DOI] 10.1099/jgv.0.001692 PMC 바로가기 [Article Type] Animal
Antibody conversion rates to SARS-CoV-2 in saliva from children attending summer schools in Barcelona, Spain스페인 바르셀로나에있는 여름 학교에 다니는 어린이들로부터 타액에서 SARS-COV-2 로의 항체 전환율Research Article Published on 2021-11-232022-09-01 Journal: BMC Medicine [Category] MERS, SARS, 변종, 진단, 치료기술, 치료법, 치료제, [키워드] age anti-spike antibodies antibody Antibody conversion antibody profiling Antigen approach Asymptomatic Barcelona children collected contagious COVID-19 COVID-19 pandemic cross-reactive antibodies cumulative defined detect evaluated faster females FIVE Health Policies IgA IgA antibodies IgA antibody IgA level IgA levels IgG IgG level IgG levels IgM increase in individual infection rate initial isotype Luminex assay management MOST Non-invasive nucleocapsid Pandemics pediatric Population protective role public health recommendation reporting symptom required Result RT-PCR Saliva SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigens SARS-COV-2 infection School Schools significantly higher Spain supplementary material symptomatic individuals variants Viral viral epidemics Viral load Viral transmission [DOI] 10.1186/s12916-021-02184-1 PMC 바로가기 [Article Type] Research Article
The (Still Unknown) Hypothetical Protective Role of COVID-19 Therapy in Bladder CancerCommunication Published on 2021-11-232022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] Bladder cancer COVID COVID-19 COVID-19 pandemic COVID-19 therapy feature implication Infection protective role reported repurposing/repositioning modality role Still therapy Treatment Unknown [DOI] 10.3390/jcm10235473 PMC 바로가기 [Article Type] Communication
Age-Related Expression of IFN-λ1 Versus IFN-I and Beta-Defensins in the Nasopharynx of SARS-CoV-2-Infected IndividualsImmunology Published on 2021-11-102022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] age Ageing analyzed Anti-viral Antiviral Asymptomatic Comorbidities COVID - 19 defensin effective expression expression pattern form forms Gender groups heterogeneous Host identify IFITM1 IFITM3 IFN - interferon IFN-I IFN-α IFN-β IFN-λ1 individual induce infected with SARS-CoV-2 Infection innate immune innate immune response Innate immunity interferon interferon-stimulated gene intrinsic LL-37 Local modulation mRNA expression mRNA level mucosa mucosal mucosal immunity nasopharyngeal nasopharyngeal mucosa Nasopharyngeal swab occur pediatric peptide Primary infection protective role Protein reached SARS – CoV – 2 SARS-CoV-2 SARS-CoV-2 coronavirus SARS-COV-2 infection selected selective subject subjects susceptibility symptomatic Symptoms the SARS-CoV-2 triggered type I type III upregulated upregulation virus β-defensin [DOI] 10.3389/fimmu.2021.750279 PMC 바로가기 [Article Type] Immunology
Impact of Bacillus Calmette-Guérin (BCG) vaccination on postoperative mortality in patients with perioperative SARS-CoV-2 infectionResearch Letter Published on 2021-11-082022-10-28 Journal: BJS Open [Category] COVID-19, MERS, SARS, [키워드] 30-Day mortality Bacillus Bacillus Calmette-Guérin BCG BCG vaccination Evidence Impact Mortality Patient postoperative PROTECT protective role pulmonary complication SARS-CoV-2 infected patient SARS-COV-2 infection SARS-CoV-2 vaccination vaccination [DOI] 10.1093/bjsopen/zrab131 PMC 바로가기 [Article Type] Research Letter
T cell-oriented strategies for controlling the COVID-19 pandemic코로나19 팬데믹을 통제하기 위한 T 세포 중심 전략Article Published on 2021-11-012022-09-11 Journal: Nature reviews. Immunology [Category] SARS, 변종, 임상, [키워드] antibody Antibody titre antibody titres conservation COVID-19 COVID-19 pandemic decay Epitopes Host Neutralizing antibodies neutralizing antibody pandemic protective role SARS-CoV-2 variant SARS-CoV-2 variants T cell T cell epitope T cell epitopes T cells thought vaccination variants of SARS-CoV-2 [DOI] 10.1038/s41577-021-00625-9 PMC 바로가기 [Article Type] Article