protein structure – Page 6 – Communicable Diseases Research

On the Prevalence and Potential Functionality of an Intrinsic Disorder in the MERS-CoV Proteome

Article

Published on 2021-02-222022-10-28
Journal: Viruses [Category] Coronavirus, MERS,

Structure Unveils Relationships between RNA Virus Polymerases

Article

Published on 2021-02-172022-10-28
Journal: Viruses [Category] COVID-19,

Generalized linear models provide a measure of virulence for specific mutations in SARS-CoV-2 strains

일반화된 선형 모델은 SARS-CoV-2 균주의 특정 돌연변이에 대한 독성 측정값을 제공합니다.

Research Article

Published on 2021-01-262022-09-10
Journal: PLoS ONE [Category] 변종, 치료법,

Structure, Activation and Regulation of NLRP3 and AIM2 Inflammasomes

Review

Published on 2021-01-162022-10-29
Journal: International Journal of Molecular Sciences [Category] COVID-19,

Domains and Functions of Spike Protein in SARS-Cov-2 in the Context of Vaccine Design

백신 설계의 맥락에서 SARS-Cov-2에서 스파이크 단백질의 도메인 및 기능

Review

Published on 2021-01-142022-09-10
Journal: Viruses [Category] 변종,

The 2021 Nucleic Acids Research database issue and the online molecular biology database collection

AcademicSubjects/SCI00010

Published on 2021-01-082022-10-31
Journal: Nucleic Acids Research [Category] COVID-19, MERS,

[키워드] acid Biology Cancer change Collection COVID-19 database domain Drivers eliminating include issue KEGG kinases Major metabolism microbial Molecular biology nucleic acid offer organism PDB Pfam plant Protein protein structure resource Rfam SARS-CoV-2 UCSC Genome Browser viral genome virus website
[DOI] 10.1093/nar/gkaa1216 PMC 바로가기 [Article Type] AcademicSubjects/SCI00010

[Homologous modeling and binding ability analysis of Spike protein after point mutation of severe acute respiratory syndrome coronavirus 2 to receptor proteins and potential antiviral drugs]

[심각한 급성 호흡기 증후군 코로나 바이러스 2의 수용체 단백질 및 잠재적 항바이러스 약물에 대한 점 돌연변이 후 스파이크 단백질의 상동 모델링 및 결합 능력 분석]

Article

Published on 2020-12-212022-09-11
Journal: Beijing da xue xue bao. Yi xue ban = Journal of Pe [Category] SARS, 변종, 치료제,

[키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affinity affinity binding Amino acid aminopeptidase aminopeptidase N Analysis angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 Antiviral aplaviroc APN AutoDock binding ability Bioinformatics analysis CD13 CD26 change Chimera Chinese conducted coronavirus dipeptidyl peptidase Dipeptidyl peptidase-4 docking DPP4 drug drug candidates drugs English enzyme evaluated Frequency functional glycoprotein greater HIV homologous host receptor Host receptors human cell human cells Human immunodeficiency virus human infection immunodeficiency immunodeficiency virus Infection molecular molecular docking simulation mutate mutated Mutation natural mutation natural mutations peptidase Point mutation PolyPhen-2 Protein protein structure receptor receptor protein respiratory S protein SARS-CoV-2 sequence Sequence alignment Sequencing Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus significantly higher small molecule spike spike glycoprotein Spike glycoprotein, coronavirus. Spike protein spontaneous mutation Taking the S protein Treatment unique virus was performed was used weakened ZDOCK
[DOI] 10.19723/j.issn.1671-167X.2021.01.023 PMC 바로가기 [Article Type] Article

Host DDX Helicases as Possible SARS-CoV-2 Proviral Factors: A Structural Overview of Their Hijacking Through Multiple Viral Proteins

Chemistry

Published on 2020-12-102022-10-31
Journal: Frontiers in Chemistry [Category] COVID-19,

SARS-CoV-2: Structure, Biology, and Structure-Based Therapeutics Development

SARS-CoV-2: 구조, 생물학 및 구조 기반 치료제 개발

Review

Published on 2020-11-252022-09-11
Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 유전자 메커니즘, 진단, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibodies Antiviral compounds approach Biology biology of SARS-CoV-2 caused Characteristics Comprehensive coronavirus COVID-19 development disease drug epidemiological Evolution Host hosts indicated information Interaction introduced life limitation mechanism pandemic Perspective Protein protein structure protein structures provided receptor respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 research severe acute respiratory syndrome coronavirus 2 Structure the epidemic therapeutic Therapeutics threat Vaccine Vaccines virus
[DOI] 10.3389/fcimb.2020.587269 PMC 바로가기 [Article Type] Review

Evidence for mutations in SARS-CoV-2 Italian isolates potentially affecting virus transmission

바이러스 전파에 잠재적으로 영향을 미칠 수 있는 SARS-CoV-2 이탈리아 분리주의 돌연변이에 대한 증거

Article

Published on 2020-10-012022-09-11
Journal: Journal of medical virology [Category] MERS, SARS, 변종, 유전자 메커니즘, 진단, 치료법,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affecting Amino acid Analysis binding bioinformatics Cell cell receptor changes in China Chinese Chinese patients coding coronavirus coronavirus disease country COVID-19 disease evaluated favor Interpretation isolate Italian Italian patient Italian patients Italy molecular molecular evolution molecule Mutation nonsynonymous mutation nucleocapsid Pandemia Protein protein stability protein structure reduce reported respiratory SARS Coronavirus SARS-CoV-2 SARS-CoV-2 genome sequence SARS-CoV-2 genome sequences sequence spike glycoprotein torsional Transmission Viral Viral protein Viral proteins Viral transmission virus virus transmission
[DOI] 10.1002/jmv.26104 PMC 바로가기 [Article Type] Article