Internet of Things with Deep Learning-Based Face Recognition Approach for Authentication in Control Medical SystemsResearch Article Published on 2022-02-122022-10-31 Journal: Computational and Mathematical Methods in Medicine [Category] Coronavirus, COVID19(2023년), MERS, SARS, [키워드] Accuracy Algorithm approach Authentication cascade Classifier CNN Control coronavirus disease COVID-19 database deep deep learning disease ENhance extraction step face facial healthcare Healthcare systems help identity Infectious disease information Internet linear overcome Raspberry Pi Recognition recognize SQL Support SVM System this system [DOI] 10.1155/2022/5137513 PMC 바로가기 [Article Type] Research Article
Escape from recognition of SARS-CoV-2 variant spike epitopes but overall preservation of T cell immunitySARS-CoV-2 변이 스파이크 에피토프의 인식에서 벗어나 T 세포 면역의 전반적인 보존Article Published on 2022-02-092022-09-11 Journal: Science Translational Medicine [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, 치료제, [키워드] Ability to protect Affect African Beta Beta variant CD4 CD4 T cells CD8 CD8 T cell CD8 T cell responses COVID-19 patient detectable dominant Efficacy epitope Epitopes escape explain First wave first-wave immune evasion Immunity immunogenic mounted mutated neutralization neutralizing antibody observation Patient patients peptide peptides preserved proportion PROTECT Recognition recognize Region regions Reinfection residue response retained robust SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants severe COVID-19 severe disease South spike epitope spike epitopes spike mutation spike mutations T cell T cell response T cell responses T cells tested Vaccine vaccine efficacy variant wild-type Wuhan strain [DOI] 10.1126/scitranslmed.abj6824 PMC 바로가기 [Article Type] Article
Role of Urinary Kidney Stress Biomarkers for Early Recognition of Subclinical Acute Kidney Injury in Critically Ill COVID-19 Patients중환자 COVID-19 환자에서 무증상 급성 신장 손상의 조기 인식을 위한 요로 신장 스트레스 바이오마커의 역할Article Published on 2022-02-082022-09-11 Journal: Biomolecules [Category] 바이오마커, [키워드] 95% CI acute kidney Acute kidney injury Admission AKI binding Biomarker Biomarkers clinical information clinical trials collected Combination Comorbidities concentrations contribute COVID-19 COVID-19 patient COVID-19 patients critical care area Critically ill critically ill COVID-19 patients Critically ill patient critically ill patients develop Early detection Gender growth factor Hospitalization IGFBP7 Ill individual information insulin insulin like growth factor binding protein 7 kidney laboratory data longitudinal cohort study male Mortality neutrophil Neutrophil gelatinase-associated lipocalin on admission persistent proportion Protein Recognition risk factor Risk factors role significantly higher Stress study outcome study outcomes Subclinical Tissue Inhibitor tissue inhibitor of metalloproteinases-2 urinary urinary kidney stress biomarkers. were recorded with COVID-19 [DOI] 10.3390/biom12020275 PMC 바로가기 [Article Type] Article
SARS-CoV-2-Specific Immune Response and the Pathogenesis of COVID-19SARS-CoV-2-특이 면역 반응과 COVID-19의 병인Review Published on 2022-02-022022-09-10 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 acute viral infection adaptive Adaptive immunity angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 Antiviral Autoimmune Autoimmunity blockade causative agent cell receptors cells cellular stress Characteristics complications of COVID-19 coronavirus coronavirus disease COVID-19 Critical Cytokines Engagement expressing Factor focus Immunity immunosuppressive include induce infect infected cell infected cells Infection Inflammation initial initial stages Innate immunity interferons Invasion invasion stage involved main receptor majority mechanism molecular mechanism molecular mechanisms overcome pathogenic pathogenicity pathway Post-COVID-19 syndrome Protein receptor receptors Recognition redundancy research finding research findings respiratory response SARS-CoV-2 severe acute respiratory syndrome Coronavirus Spike protein Stage superantigens systemic inflammation target cell the spike protein tissue variant variants Viral virulence virus [DOI] 10.3390/ijms23031716 PMC 바로가기 [Article Type] Review
Computational methods for inferring location and genealogy of overlapping genes in virus genomes: approaches and applications바이러스 게놈에서 겹치는 유전자의 위치 및 계보를 추론하는 전산 방법: 접근 방식 및 응용Review Published on 2022-02-012022-09-11 Journal: Current opinion in virology [Category] COVID19(2023년), SARS, 치료기술, [키워드] accessory proteins applied approach Atypical Computational methods COVID-19 pandemic detect etiological agent facilitate feature Genes genetic information Genome genomes in viral limitations Metrics nine overlap overlapping pathogenicity Recognition SARS-CoV-2 Spread statistically significant reduction synonymous Variability viral pathogenicity virus [DOI] 10.1016/j.coviro.2021.10.009 PMC 바로가기 [Article Type] Review
Neutralizing Antibody Responses to SARS-CoV-2 in Recovered COVID-19 Patients Are Variable and Correlate With Disease Severity and Receptor-Binding Domain RecognitionImmunology Published on 2022-01-312022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, [키워드] acute respiratory syndrome adopted antibodies caused characterized contribute coronavirus country COVID-19 COVID-19 convalescent patient COVID-19 recovered patients criteria Critical domain elicited ELISA Europe Factor Health Service highlighting humoral humoral immune response Humoral response IgG immune protection implication individuals infected individuals influence knowledge Live virus Mild natural infection neutralization neutralization activity neutralization potency outbreak pandemic parameter proportion pseudovirus public health RBD RBD-targeting antibody Recognition recovered response SARS-CoV-2 SARS-COV-2 infection serological serum sample Severe patient significantly higher specificity spike triggered understanding vaccination Variability variable [DOI] 10.3389/fimmu.2022.830710 PMC 바로가기 [Article Type] Immunology
Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules Research Published on 2022-01-312022-10-05 Journal: Nature Immunology [Category] COVID19(2023년), SARS, 바이오마커, 변종, 유전자 메커니즘, [키워드] activated Activation acute respiratory syndrome binding Biomarker complement coronavirus coronavirus disease COVID-19 disease severity functions glycosylation site humoral Implications in vitro include inhibited Innate immunity Interaction lectin pathway locus MBL2 omicron Pathogenesis polymorphism predicted Ptx3 Recognition recognize SARS-CoV-2 selected Spike protein Spike proteins tested the viral nucleocapsid translational Trimeric spike protein variants of concern [DOI] 10.1038/s41590-021-01114-w [Article Type] Research
Current and Future Perspectives on the COVID-19 Vaccine: A Scientometric ReviewReview Published on 2022-01-292022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] articles bibliometric analysis conducted contributing to country COVID-19 COVID-19 vaccination COVID-19 vaccine COVID-19 virus current Department Effects Future Harvard Medical School Health healthcare worker highest Human immunology media Perspective receiving Recognition Research Research topics Research trends researchers review scientific collaboration service the vaccine United State university University of Oxford Vaccine Vaccines Web of Science were used [DOI] 10.3390/jcm11030750 PMC 바로가기 [Article Type] Review
Commentary: Pattern Recognition Proteins: First Line of Defense Against CoronavirusesImmunology Published on 2022-01-262022-11-01 Journal: Frontiers in Immunology [Category] Coronavirus, [키워드] adult respiratory distress syndrome Against Bronchoalveolar lavage COVID-19 LINE pattern Recognition SARS CoV 2 surfactant protein-D viral aggregation [DOI] 10.3389/fimmu.2022.815168 PMC 바로가기 [Article Type] Immunology
N7-Methylation of the Coronavirus RNA Cap Is Required for Maximal Virulence by Preventing Innate Immune RecognitionResearch Article Published on 2022-01-252022-10-29 Journal: mBio [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] ACE2 acute respiratory syndrome Brain CAP caused comparable Complete contribute coronavirus coronavirus disease CoV COVID-19 disease effective vaccine exhibited expression guanine IFN-I immune response immunological in vitro Infection Innate interferons ISG15 liver MDA5 MHV mice morbidity and mortality mouse hepatitis virus mutant mutant virus Mutation myeloid cell N7-methylation nonstructural protein 14 nonstructural protein 14 (nsp14) nsp14 pandemic Pathogenesis phenotype Prevent Preventing previous study Recognition reduced replicated required restored RNA RNA cap structure RNA methylation SARS-CoV-2 SARS-COV-2 infection Signaling significantly subsequent the vaccine therapy transgenic mice type I interferon understanding upregulated viral replication Viral RNA virulence wild-type [DOI] 10.1128/mbio.03662-21 PMC 바로가기 [Article Type] Research Article