Respiratory distress syndrome – Page 6 – Communicable Diseases Research

Alveolar, Endothelial, and Organ Injury Marker Dynamics in Severe COVID-19

심각한 COVID-19의 폐포, 내피 및 장기 손상 마커 역학

Observational Study

Published on 2022-03-012022-09-11
Journal: American Journal of Respiratory and Critical Care [Category] MERS, SARS, 바이오마커, 임상,

Immunomodulatory agents for COVID-19 treatment: possible mechanism of action and immunopathology features

COVID-19 치료용 면역조절제: 가능한 작용 기전 및 면역병리학적 특징

Review

Published on 2022-03-012022-09-11
Journal: Molecular and cellular biochemistry [Category] MERS, 진단, 치료기술, 치료제,

[키워드] ACE2 acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis angiotensin Angiotensin-converting enzyme Anosmia antagonists applied ARDS blood vessel body aches cause clinical trial clinical trials coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 COVID-19 case COVID-19 patient COVID-19 patients COVID-19 treatment Critical critical patients cytokine Cytokine storm Cytokines demonstrated described drug drugs dry cough Endothelial cell endothelial cells excessive secretion feature Fever Health Organization immune system immunomodulatory immunopathology immunosuppressive agent Immunosuppressive agents incidence include Infection Inflammatory responses interleukin investigated lead Lungs mAbs mechanical ventilator mechanism mechanism of action medication membrane mitigate modulating monoclonal antibodies monoclonal antibody mortality rates new virus Novel coronavirus overproduction oxygen Oxygen therapy pandemic pathophysiology Patient patients penetrate Physicians pro-inflammatory factors receptor reduce mortality researchers respiratory respiratory distress Respiratory distress syndrome SARS-CoV-2 severe acute respiratory syndrome Coronavirus signaling pathway signaling pathways stimulate Support Symptom syndrome the disease therapeutic compound treat triggering virus World Health Organization Wuhan Wuhan, China
[DOI] 10.1007/s11010-021-04325-9 PMC 바로가기 [Article Type] Review

A computational and bioinformatic analysis of ACE2: an elucidation of its dual role in COVID-19 pathology and finding its associated partners as potential therapeutic targets

ACE2의 컴퓨터 및 생물정보학 분석: COVID-19 병리학에서 ACE2의 이중 역할에 대한 설명 및 잠재적인 치료 표적으로서 관련 파트너 찾기

Article

Published on 2022-03-012022-09-11
Journal: Journal of biomolecular structure & dynamics [Category] SARS, 유전자 메커니즘,

[키워드] ACE2 acting acute respiratory distress acute respiratory distress syndrome Acute respiratory distress syndrome Predicted ACE2 structure Analysis analyzed angiotensin Angiotensin-converting enzyme Angiotensin-converting enzyme -2 angiotensin-converting enzyme 2 ARDS bioinformatic analysis CDS Cell coding COVID-19 pandemic COVID-19 pathology determine Differentially expressed genes disease distress DNA sequence downregulation effort enzyme FOS FOXO4 FOXP2 healthy human lung tissue involved list low expression mechanism MiR-212-5p miRNA miRNA target miRNA targets miRNA-1246. pandemic pathological changes potential therapeutic target provide receptor respiratory distress Respiratory distress syndrome Spike protein Spread syndrome transcription factor transcription factors upregulation Vaccine viral entry viral spike protein
[DOI] 10.1080/07391102.2020.1833760 PMC 바로가기 [Article Type] Article

Thrombosis pathways in COVID‐19 vs. influenza‐associated ARDS: A targeted proteomics approach

Article

Published on 2022-02-272023-06-14
Journal: Journal of thrombosis and haemostasis : JTH [Category] COVID19(2023년), MERS, SARS,

[키워드] COVID‐19 Influenza Pulmonary embolism Respiratory distress syndrome thrombosis
[DOI] 10.1111/jth.15671 PMC 바로가기

Protease-anti-protease compartmentalization in SARS-CoV-2 ARDS: Therapeutic implications

SARS-CoV-2 ARDS의 프로테아제-항-프로테아제 구획화: 치료적 의미

Articles

Published on 2022-02-222022-09-11
Journal: EBioMedicine [Category] COVID19(2023년), SARS, 치료기술, 치료제,

[키워드] acute respiratory distress acute respiratory distress syndrome airway airways Alpha alpha-1 antitrypsin ARDS ARDS patients balance circulation cleavage cleaved detectable down-regulated Effect elevated evaluated finding IL-6 IL-6 level IL-6 receptor implication induction inhibitor interleukin interleukin-6 investigated involved less Level lung lung parenchyma moderate NET neutrophil Neutrophil elastase Neutrophils occurred patients plasma protease Proteins receptor antagonist regulate respiratory distress Respiratory distress syndrome SARS-CoV-2 SARS-CoV-2 ARDS SARS-COV-2 infection secretion Standard of care syndrome target therapy tissue Tocilizumab tracheal were measured
[DOI] 10.1016/j.ebiom.2022.103894 PMC 바로가기 [Article Type] Articles

High procalcitonin levels associated with increased intensive care unit admission and mortality in patients with a COVID-19 infection in the emergency department

응급실에서 COVID-19 감염 환자의 집중 치료실 입원 및 사망률 증가와 관련된 높은 Procalcitonin 수준

Research Article

Published on 2022-02-212022-09-10
Journal: BMC Infectious Diseases [Category] COVID19(2023년), Fulltext, MERS, SARS, 바이오마커,

[키워드] 105 patient 105 patients 95% CI 95% confidence interval acute respiratory distress acute respiratory distress syndrome adjusted Admission age Analysis ARDS assist association AUC Bacterial bacterial coinfections Biomarker Biomarkers C-reactive protein C-reactive protein (CRP calculate center clinical decision Comorbidities Comorbidity Confirmed COVID-19 infection COVID-19 COVID-19 infection COVID-19 infections CRP D-dimer Decision making decision making process defined develop elevated emergency department Erasmus Final final analysis hospital discharge Hospital mortality hyperinflammation ICU ICU admission in-hospital mortality intensive care intensive care unit Logistic regression Mortality multivariable model Netherlands Odds ratio outcome Patient patients with COVID-19 PCT physician Primary outcome procalcitonin procalcitonin level reached required respiratory distress Respiratory distress syndrome Result retrospective cohort study Severe COVID-19 Infection severe COVID-19 infections Sex significantly supplementary material syndrome were measured
[DOI] 10.1186/s12879-022-07144-5 PMC 바로가기 [Article Type] Research Article

Silymarin/curcumin loaded albumin nanoparticles coated by chitosan as muco-inhalable delivery system observing anti-inflammatory and anti COVID-19 characterizations in oleic acid triggered lung injury and in vitro COVID-19 experiment

키토산으로 코팅된 실리마린/커큐민 로딩 알부민 나노입자는 올레산 유발 폐 손상 및 시험관 내 COVID-19 실험에서 항염증 및 항 COVID-19 특성을 관찰하는 점막 흡입성 전달 시스템

Article

Published on 2022-02-152022-09-11
Journal: International journal of biological macromolecules [Category] 비임상, 치료제,

[키워드] acute respiratory distress acute respiratory distress syndrome albumin alveolar Anti-inflammatory anti-viral activity assembly bovine bovine serum albumin BSA C-reactive protein can be used candidate chitosan coated coronavirus COVID-19 edema Efficacy ENhance experiment Health health problem hyaline membrane hyaline membranes hyperplasia identify in vitro infected patient infected patients Inflammation inflammatory process interleukin interleukin-6 Lung injury lung lesion lung lesions moment Mucoadhesive. oleic acid overcome Pneumonia Polymer Protein reduction in respiratory respiratory distress Respiratory distress syndrome septal serum albumin silymarin syndrome treated Treatment treatment of COVID-19 triggered virus
[DOI] 10.1016/j.ijbiomac.2021.12.073 PMC 바로가기 [Article Type] Article

Pathophysiology of coronavirus-19 disease acute lung injury

Article

Published on 2022-02-132023-06-15
Journal: Current opinion in critical care [Category] COVID19(2023년), MERS, SARS,

[키워드] Coronavirus-19 disease Critical care Physiology respiratory Respiratory distress syndrome SARS-CoV-2
[DOI] 10.1097/MCC.0000000000000911 PMC 바로가기

Galectin-3 as a potential prognostic biomarker of severe COVID-19 in SARS-CoV-2 infected patients

SARS-CoV-2 감염 환자에서 심각한 COVID-19의 잠재적 예후 바이오마커로서의 Galectin-3

Observational Study

Published on 2022-02-032022-09-10
Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 바이오마커, 임상, 치료기술,

[키워드] 95% CI acute respiratory distress acute respiratory distress syndrome Admission Airway inflammation albumin allocation Analysis ARDS binding Biomarker characteristic clinician Combination contributing to correlated COVID-19 COVID-19 patient COVID-19 patients COVID-19 severity CRP Cytokines D-dimer death defined determine discharge Evidence facilitate galectin-3 highest Hyperinflammatory IMV In-hospital death independent Invasive mechanical ventilation Logistic regression analysis marker multi-organ failure multivariable logistic regression Multivariable logistic regression analysis neutrophil neutrophil count neutrophil infiltration NLR Odds ratio outcome outcomes Patient predict Predictive markers pro-inflammatory cytokine pro-inflammatory cytokines prognostic prognostic biomarker receiver operating characteristic resource respiratory distress Respiratory distress syndrome risk ROC RT-PCR SARS-CoV-2 infected patient serum severe COVID-19 significantly syndrome viral infection
[DOI] 10.1038/s41598-022-05968-4 PMC 바로가기 [Article Type] Observational Study

Late bilateral vocal cord palsy following endotracheal intubation due to COVID-19 pneumonia

Case Reports

Published on 2022-02-012023-07-08
Journal: Revista española de anestesiología y reanimació [Category] COVID19(2023년),

[키워드] COVID-19 infecciones por coronavirus Intubación intratraqueal Intubation intratracheal Neumonía viral Parálisis de los pliegues vocales Pneumonia viral Respiratory distress syndrome Síndrome de dificultad respiratoria del adulto tracheotomy Traqueotomía Vocal cords paralysis.
[DOI] 10.1016/j.redare.2020.11.012 PMC 바로가기 [Article Type] Case Reports