Clinical profile of patients infected with suspected SARS-CoV-2 Omicron variant of concern, Tamil Nadu, India, December 2021-January 2022Article Published on 2022-01-012022-11-16 Journal: The Indian journal of medical research [Category] SARS, 변종, [키워드] B.1.1.529 Characteristics clinical Clinical characteristics Clinical course Clinical outcome conducted cough country Course COVID-19 COVID-19 case COVID-19 patient COVID-19 vaccines death dose enrolled epidemiological Epidemiology Fever gene target India Infection information Laboratory less Mild omicron outcome oxygen supplementation Pain Patient patients positive result Randomly reported required reverse transcription-PCR rising S gene SARS-CoV-2 selected Seven severity socio-demographic Symptom the SARS-CoV-2 Treatment vaccination variant variant of concern VoC with COVID-19 [DOI] 10.4103/ijmr.ijmr_312_22 PMC 바로가기
Mutation profile of SARS-CoV-2 genome in a sample from the first year of the pandemic in Colombia콜롬비아에서 전염병이 발생한 첫해 샘플에서 SARS-CoV-2 게놈의 돌연변이 프로필Article Published on 2022-01-012022-09-11 Journal: Infection, genetics and evolution : journal of mol [Category] SARS, 변종, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus base pairs Beta CDC circulating clade collected concern coronavirus correlation COVID-19 D614G diagnostic diagnostic test disease severity E484K Effectiveness Evidence followed by Gamma genetic change genetic information Genetic variation genomic genomic variant GISAID Health Organization High-throughput nucleotide sequencing host immunity interest L18F lAbel Lineage Missense MOST Mutation next generation sequencing NGS non-structural proteins nucleotide ORF1ab gene pandemic predominant recent regions S gene SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 variants sequenced South America structural protein structural proteins Surveillance synonymous the SARS-CoV-2 genome the WHO Vaccines variants virus VoC WHO Whole genome sequencing World Health Organization [DOI] 10.1016/j.meegid.2021.105192 PMC 바로가기 [Article Type] Article
Evaluation of sample pooling using the SAMBA II SARS-CoV-2 testSAMBA II SARS-CoV-2 테스트를 사용한 샘플 풀링 평가Article Published on 2022-01-012022-09-12 Journal: Journal of virological methods [Category] MERS, SARS, 진단, [키워드] affected Asymptomatic collected Combined conducted COVID COVID-19 COVID-19 pandemic expand false-negative implementation independent indicated individual limit molecular testing negative swab NHS non-infected nose and throat Patient point-of-care pool pool testing positive positive sample pre-symptomatic Preliminary data Prevalence protocol provided qRT-PCR reduce reference method S gene SAMBA SAMBA II SAMBA II SARS-CoV-2 SARS-CoV-2 Screening Sensitivity and specificity significantly specificity Swab tested the SARS-CoV-2 Viral load [DOI] 10.1016/j.jviromet.2021.114340 PMC 바로가기 [Article Type] Article
Analysis of Clinical Characteristics and Virus Strains Variation of Patients Infected With SARS-CoV-2 in Jiangsu Province—A Retrospective Study장쑤성 SARS-CoV-2 감염 환자의 임상적 특성 및 바이러스 균주 변이 분석 - 후향적 연구Public Health Published on 2021-12-242022-09-11 Journal: Frontiers in Public Health [Category] MERS, SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age Alpha Amino acid amino acid replacement amino acid replacements amino acid substitution Analysis association Asymptomatic asymptomatic infection Beta caused change Characteristics China clinical Clinical characteristics Clinical features Clinical severity collected concern conditions confirmed case coronavirus correlated Course Delta detect diagnosed disease Diversity dominant dominant mutation Evolution Frame Genetic genomic genomic variation help hosts imported cases infected patient Infection Jiangsu Last local outbreak local outbreaks loci men Missense mutation MONITOR Mutation mutations nine nucleotide occurred Open reading frame ORF1ab oropharyngeal swab oropharyngeal swabs Patient patients patients severity patients severity SARS-CoV-2 pedigree pharyngeal swabs Phylogeny positively correlated present Recombination respiratory risk S gene SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2 variants Sequencing severity significantly Single nucleotide polymorphism single nucleotide polymorphisms SNP SNPs spike glycoprotein Spread strain Surveillance the SARS-CoV-2 undergo variant variety virus virus variant viruses was performed was used were infected whole genome Whole genome sequencing women [DOI] 10.3389/fpubh.2021.791600 PMC 바로가기 [Article Type] Public Health
Molecular Characterization of Infectious Bronchitis Virus Strain HH06 Isolated in a Poultry Farm in Northeastern ChinaVeterinary Science Published on 2021-12-162022-11-01 Journal: Frontiers in Veterinary Science [Category] COVID-19, [키워드] Analysis bovine characterization characterized China clade clades coronavirus Coronaviruses CoV CoVs domain Epidemic Evolution explain farm Genetic Genome glycoprotein HCoV-OC43 Host IBV indicated Infectious Bronchitis Virus Isolated maintain mammalian MERS-CoV Molecular epidemiology motif Phylogenetic Phylogenetic relationship poultry protein sequence Recombination S gene S protein SARS CoV-2 SARS-CoV SARS-CoV-2 selected selection pressure sequence spike Spread strain variant virulent viruses zoonosis [DOI] 10.3389/fvets.2021.794228 PMC 바로가기 [Article Type] Veterinary Science
Whole-genome sequencing of SARS-COV-2 showed wide spread of B.1.525 in February 2021 in LibyaSARS-COV-2의 전체 게놈 시퀀싱은 2021년 2월 리비아에서 B.1.525의 광범위한 확산을 보여주었습니다.Article Published on 2021-12-012022-09-11 Journal: The Libyan journal of medicine [Category] SARS, 변종, 치료기술, [키워드] Alpha amplification B.1.1.7 B.1.525 can not cause center characteristic circulating circulating variants collected Control COVID-19 Denmark diagnostic disease control Frequency Human identify International Laboratory Libya Mutation new variants. other variant other variants pandemic performed positive quantitative PCR Research RT-qPCR RT-qPCR assay RT-qPCR assays S gene SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants Sequencing Spread suggested tested Transmissibility variant variants virus whole genome Whole genome sequencing whole-genome sequencing [DOI] 10.1080/19932820.2021.2001210 PMC 바로가기 [Article Type] Article
Rapid screening for SARS-CoV-2 VOC-Alpha (202012/01, B.1.1.7) using the Allplex™ SARS-CoV-2/FluA/FluB/RSV AssayAllplex™ SARS-CoV-2/FluA/FluB/RSV Assay를 사용한 SARS-CoV-2 VOC-Alpha(202012/01, B.1.1.7)의 신속한 스크리닝Article Published on 2021-12-012022-09-11 Journal: International Journal of Infectious Diseases [Category] SARS, 변종, 치료기술, [키워드] Affect Alpha alteration analyzed average B.1.1.7 B.1.1.7 lineage can be used carried COVID-19 Cq values Definition Delta diagnostic Diego epidemiological epidemiological surveillance exhibited Gamma Genomic alterations Illumina Miseq in some Lineage Lineage B.1.1.7 N gene Oxford Oxford Nanopore Technologies platform profile Rapid Rapid screening method Region regions RT-PCR RT-qPCR RT-qPCR assay RT-qPCR assays S gene S-gene Sample Sanger sequencing SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV-2 VoC Sequencing South Korea specimens Surveillance TaqPath technology the SARS-CoV-2 Thermo Fisher Scientific Transmissibility USA variant variants Viral detection VoC VOCs WGS whole genome Whole genome sequencing wild-type [DOI] 10.1016/j.ijid.2021.10.005 PMC 바로가기 [Article Type] Article
Development of a Single-Cycle Infectious SARS-CoV-2 Virus Replicon Particle System for Use in Biosafety Level 2 LaboratoriesVirus-Cell Interactions Published on 2021-12-012022-10-30 Journal: Journal of Virology [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] 3CL activity acute respiratory syndrome addition anti-CoV drug antiviral drug antiviral drugs biosafety Biosafety Level 2 Biosafety Level 3 BSL2 BSL3 Cell cell types conditions contagious coronavirus CoV decrease deleting development drug dose ENCODE expressing expression fluorescent GFP glycoprotein glycoprotein G host cells Immunity Infection Laboratory lack murine mutant neutralized Particle platform Protease inhibitor Protein Remdesivir replication of SARS-CoV-2 replicon reporter reporters Research robust S gene SARS-CoV-2 SARS-CoV-2 biology SARS-CoV-2 research SARS-CoV-2 virus Scientific community serum spike gene Support System Treatment Vaccine variety vesicular stomatitis virus viral envelope viral genome viral glycoproteins VSV [DOI] 10.1128/jvi.01837-21 PMC 바로가기 [Article Type] Virus-Cell Interactions
A Routine Sanger Sequencing Target Specific Mutation Assay for SARS-CoV-2 Variants of Concern and InterestArticle Published on 2021-11-292022-10-28 Journal: Viruses [Category] COVID-19, MERS, SARS, [키워드] accumulate ACE2 ACE2 RBD Amino acid amino acid mutations Amplicon amplify angiotensin-converting enzyme 2 caused cDNA center circulating concern Control Critical deletions delta variant diagnostics effort fraction generate genetic change human populations interest Mutation mutations N-terminal domain N-terminal domain (NTD) nested RT-PCR NTD nucleic acid nucleic acid target occur positive Precision prevention Protein protocol RBD Receptor binding domain Region routine RT-PCR S gene Sanger sequencing SARS-CoV-2 sequence Sequencing Specific specimen Spike protein Spread Surveillance target the S protein Vaccines variants variants of concern variants of interest Viral load virus whole genome [DOI] 10.3390/v13122386 PMC 바로가기 [Article Type] Article
Molecular characterization of the FCoV-like canine coronavirus HLJ-071 in ChinaResearch Published on 2021-11-272022-10-28 Journal: BMC veterinary research [Category] Coronavirus, MERS, [키워드] addition Affect Analysis Antigen canine Canine coronavirus cell tropism cells changes in China Complete contributing to coronavirus dead Deletion diarrhea Evolution experiments female Genetic genotypes in viral information involved isolate Isolation ORF 3a Point mutation Recombination replicate Replication Result S gene sequence Spike protein strain suggested supplementary material transcription-regulating sequence variant virulence vomit Welsh Corgi [DOI] 10.1186/s12917-021-03073-8 PMC 바로가기 [Article Type] Research