Evaluation and comparison of conjunctival swab polymerase chain reaction results in SARS-CoV-2 patients with and without ocular manifestationsObservational Study Published on 2021-08-012022-10-05 Journal: Indian journal of ophthalmology [Category] SARS, 임상, [키워드] Admission age Comorbidity conducted conjunctival Conjunctival secretion Conjunctival secretions Control controls disease enrolled evaluate eye had no less manifestation Manifestations nasopharyngeal swabs ocular ocular manifestations Patient PCR polymerase chain positive potential risk prospective observational study RT PCR RT-PCR S-CoV-2 SAR SARS-CoV-2 SARS-CoV-2 patient SARS-CoV-2 positive patient SARS-CoV-2 positive patients severity of COVID-19 significantly statistical statistical significance statistically significant Swab Symptom tested Transmission [DOI] 10.4103/ijo.IJO_587_21 PMC 바로가기 [Article Type] Observational Study
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Setting-specific Transmission Rates: A Systematic Review and Meta-analysis심각한 급성 호흡기 증후군 코로나 바이러스 2 (SARS-COV-2) 설정 별 전송률 : 체계적인 검토 및 메타 분석Online Only Articles Published on 2021-08-012022-09-06 Journal: Clinical Infectious Diseases: An Official Publicat [Category] Communicable Disease, COVID-19, MERS, SARS, [키워드] 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Affect age asymptomatic index case asymptomatic index cases attack rates beta-binomial model Care conducted Contact Contact tracing coronavirus coronavirus 2 COVID-19 driver Drivers duration of exposure estimate event Evidence evidence of exceeded Factor family friends highest highlight highlighting household implication increase index case index case symptom status individual Intervention Isolation low-risk casual contact low-risk casual contacts negative-binomial model occur presymptomatic reduced Reproduction number reproduction numbers Research respiratory Result review SAR SARS SARS-CoV-2 SARS-CoV-2 transmission Schools secondary attack rate severe acute respiratory syndrome Coronavirus significantly higher study heterogeneity symptom status symptomatic index cases systematic review Transmissibility Transmission transmission of SARS-CoV-2 transmission pattern transmission patterns transmission potential transmission rate transmission rates understanding [DOI] 10.1093/cid/ciab100 PMC 바로가기 [Article Type] Online Only Articles
Investigating associations between COVID-19 mortality and population-level health and socioeconomic indicators in the United States: A modeling studyResearch Article Published on 2021-07-132022-10-29 Journal: PLoS Medicine [Category] COVID-19, [키워드] Adjusting age association autocorrelation calculated can be used Characteristics Chronic kidney disease collinearity COVID-19 COVID-19 mortality criteria death deaths dependent on disease Effect estimate estimates explain explained Health health condition highest include increase in Interaction limitation Mortality mortality rate National occur outbreak outcome outcomes Population predicted predictor predictors Presence Prevalence proportion R 2 reduce researcher risk risk of COVID-19 SAR selected Significant Strong Structure study population the United State The United States utility Vaccination strategy Vaccine Vaccines Variability were used with COVID-19 [DOI] 10.1371/journal.pmed.1003693 PMC 바로가기 [Article Type] Research Article
Computational Insights on the Potential of Some NSAIDs for Treating COVID-19: Priority Set and Lead OptimizationCovid-19 치료를위한 일부 NSAID의 잠재력에 대한 계산 통찰력 : 우선 순위 세트 및 리드 최적화Article Published on 2021-06-212022-08-31 Journal: Molecules [Category] MERS, SARS, 신약개발, 치료제, [키워드] addition antagonist anti-inflammatory activity anti-inflammatory effect auranofin candidate carried caused Compound compounds conducted COVID-19 cytokine DFT calculations docking drug Drug repurposing effective evaluated expected FDA-approved drug FDA-approved drugs functional Health help indomethacin Inflammation Inflammatory cytokine Inflammatory cytokine storm inhibiting inhibitor inhibitors insight lead lung damage M pro molecular docking molecular dynamics Molecular dynamics simulation molecular dynamics simulations NSAID NSAIDS optimization pandemic parameter Potential priority protease provide provoking responsible resulting Safe SAR SARS-CoV-2 SARS-CoV-2 main protease screened severity sulfinpyrazone target receptor tested therapeutic treating Treatment treatment for COVID-19 [DOI] 10.3390/molecules26123772 PMC 바로가기 [Article Type] Article
SARS CoV-2 aerosol: How far it can travel to the lower airways?ARTICLES Published on 2021-06-032022-10-28 Journal: Physics of Fluids [Category] COVID-19, [키워드] aerosol airway airways analyzed complex Concentration conditions Contact contagious disease Health help investigated knowledge lung mortality rate outbreak Particle proportion Respiratory system resulting risk SAR SARS CoV-2 significant effect Spread Transport Travel upper airway virus virus particle was performed was used [DOI] 10.1063/5.0053351 PMC 바로가기 [Article Type] ARTICLES
SARS-CoV-2 variant B.1.1.7 susceptibility and infectiousness of children and adults deduced from investigations of childcare centre outbreaks, Germany, 2021SARS-CoV-2 변종 B.1.1.7 어린이집 발병 조사에서 추론한 어린이와 성인의 감수성과 전염성, 독일, 2021년Rapid Communication Published on 2021-05-272022-09-10 Journal: Eurosurveillance [Category] SARS, 변종, [키워드] advent attack rates B.1.1.7 Child childcare centre children close contact COVID-19 Germany groups Health Households infectiousness investigated kindergarten measure occurred outbreak Outbreaks Public public health measures SAR SARS-CoV-2 SARS-CoV-2 variant secondary attack rate susceptibility VoC [DOI] 10.2807/1560-7917.ES.2021.26.21.2100433 PMC 바로가기 [Article Type] Rapid Communication
Secondary attack rates of COVID-19 in Norwegian families: a nation-wide register-based studyCovid-19 Published on 2021-05-252022-10-31 Journal: European Journal of Epidemiology [Category] COVID-19, [키워드] 95% CI age attack rate calculated children COVID-19 declined defined increasing age index case individual Infection Norway Older parent parents PCR test positive positive PCR test SAR SARS-CoV-2 secondary secondary attack rate supplementary material tested Transmission from children Transmission in family virus [DOI] 10.1007/s10654-021-00760-6 PMC 바로가기 [Article Type] Covid-19
Strong Inhibitory Activity and Action Modes of Synthetic Maslinic Acid Derivative on Highly Pathogenic Coronaviruses: COVID-19 Drug CandidateArticle Published on 2021-05-192022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] acid Action activity acute respiratory syndrome analogue anti-SARS-CoV-2 antiviral activity candidate Candidates carried chlorinated Compound concentrations coronavirus coronavirus disease COVID-19 derivative drug escaped examined global pandemic impair in vitro in vivo inhibitory concentration maslinic acid MERS-CoV mode molecular docking non-toxic Novel coronavirus oleanolic acid SAR SARS-CoV-2 SARS-CoV-2 main protease screened Strong synthetic tested Treatment viral replication [DOI] 10.3390/pathogens10050623 PMC 바로가기 [Article Type] Article
Calendulaglycoside A showing potential activity against SARS-CoV-2 main protease: Molecular docking, molecular dynamics, and SAR studiesArticle Published on 2021-05-172022-10-30 Journal: Journal of Traditional and Complementary Medicine [Category] COVID-19, [키워드] Abstract antiviral activity binding binding score C. officinalis L. caused clinically co-crystallized co-crystallized N3 inhibitor Compound compounds computational studies Course COVID-19 docking drug drug candidates targeting effective electrostatic interaction electrostatic interactions Health highlight Image inhibiting inhibitor inhibitory activity intrinsic investigated M pro MD simulation molecular molecular docking studies Molecular docking study N3 inhibitor pandemic responsible Result Safe SAR SARS-CoV-2 severity stability the SARS-CoV-2 therapeutic Trajectories Treatment treatment for COVID-19 triterpenes was performed [DOI] 10.1016/j.jtcme.2021.05.001 PMC 바로가기 [Article Type] Article
The epidemiological impact of the NHS COVID-19 app Research Published on 2021-05-122022-10-05 Journal: Nature [Category] 치료법, [키워드] 95% confidence interval complementary Contact Contact tracing COVID-19 COVID-19 pandemic England epidemiological event Evidence fraction help increase in index case individual Local National Health Service NHS Population positive Prevent public health reduced remained SAR secondary attack rate sensitivity analysis Spread statistical statistical analysis Support supported Symptom tested the disease total population Vaccines was used [DOI] 10.1038/s41586-021-03606-z [Article Type] Research