SARS-CoV-2 viral – Page 6 – Communicable Diseases Research

Screening of Natural Products Inhibitors of SARS-CoV-2 Entry

Article

Published on 2022-03-072022-10-30
Journal: Molecules [Category] COVID-19, MERS, SARS,

Racial/Ethnic Disparities in Healthcare Worker Experiences During the COVID-19 Pandemic: An Analysis of the HERO Registry

Research article

Published on 2022-03-072022-10-05
Journal: EClinicalMedicine [Category] 임상,

[키워드] adjusted odds ratio Asian black Burnout Characteristics clinical trials Community confounding factor coronavirus COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 vaccine develop Diagnosis disparity District emotional Emotional experiences enrolled equity ethnic disparities Ethnicity evaluated Evidence experience finding funding Future HCWs Health health equity healthcare healthcare worker Healthcare worker shortage Healthcare workers Hispanic Impact IMPROVE less mechanism National Nursing shortage outcome participant Participants performed Physician shortage prospective cohort study race Racial disparities receive registry SARS-CoV-2 SARS-CoV-2 viral Structural racism Systemic racism targeted intervention Testing Trial Vaccine Vaccine hesitancy Vaccine interest white with COVID-19 worker
[DOI] 10.1016/j.eclinm.2022.101314 [Article Type] Research article

Study protocol for the Innovative Support for Patients with SARS-COV-2 Infections Registry (INSPIRE): A longitudinal study of the medium and long-term sequelae of SARS-CoV-2 infection

Study Protocol

Published on 2022-03-032022-10-28
Journal: PLoS ONE [Category] COVID-19, MERS, SARS,

Design of a population-based longitudinal cohort study of SARS-CoV-2 incidence and prevalence among adults in the San Francisco Bay Area

샌프란시스코 베이 지역 성인의 SARS-CoV-2 발병률 및 유병률에 대한 인구 기반 종단 코호트 연구 설계

Article

Published on 2022-03-012022-09-11
Journal: Annals of epidemiology [Category] MERS, SARS, 진단, 치료기술, 치료법, 치료제,

[키워드] antibody Area Behavior blood sample calculated Characteristics Cohort completion COVID-19 demographics determine determined by enrolled estimate estimates Follow-up General population Health help Households identifying IMPROVE incidence Infection infections Laboratory Laboratory test longitudinal cohort study mail medium nasopharyngeal swabs Neutralizing antibodies non-responders nucleocapsid antigens participant PCR testing population sizes Population-based survey Precision predict Prevalence Probability sample questionnaire Questionnaires random reached recruit recruited Regression model regression models responders risk robust Sample size San Francisco San Francisco Bay SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2 spike SARS-CoV-2 viral SARS-CoV-2 viral detection Sociodemographic Sociodemographic characteristics stratified Surveillance unique venous venous blood Viral Viral detection virus
[DOI] 10.1016/j.annepidem.2021.11.001 PMC 바로가기 [Article Type] Article

Spatial and temporal distribution of SARS-CoV-2 diversity circulating in wastewater

폐수에서 순환하는 SARS-CoV-2 다양성의 시공간 분포

Article

Published on 2022-03-012022-09-11
Journal: Water research [Category] SARS, 변종, 치료기술,

Efficacy of Losartan in Hospitalized Patients With COVID-19-Induced Lung Injury: A Randomized Clinical Trial

COVID-19 유발 폐 손상으로 입원한 환자에서 Losartan의 효능: 무작위 임상 시험

Randomized Controlled Trial

Published on 2022-03-012022-09-25
Journal: JAMA Network Open [Category] 임상, 진단, 치료제,

[키워드] acute lung injury Administered Affect age analyzed Angiotensin-converting enzyme assigned blinded blockade clinical Clinical outcome clinical trials component conducted contributing to COVID-19 disrupt Efficacy eligible fraction homeostasis hospital hospital discharge hospitalized patient Human implication IMPROVE inhibitor losartan Lung injury median men mitigate Mortality Organ failure outcome oxygen participant Participants patients with COVID-19 Placebo placebo-controlled Primary outcome RAAS Randomized randomized clinical trial receptor reduce SARS-CoV-2 viral secondary significantly the United State Ventilation were measured with COVID-19
[DOI] 10.1001/jamanetworkopen.2022.2735 PMC 바로가기 [Article Type] Randomized Controlled Trial

Exploration of the ocular surface infection by SARS-CoV-2 and implications for corneal donation: An ex vivo study

SARS-COV-2에 의한 안구 표면 감염의 탐색 및 각막 기증에 대한 시사점 : 생체 외 연구

Research Article

Published on 2022-03-012022-09-10
Journal: PLoS Medicine [Category] MERS, SARS, 치료기술,

[키워드] 24 hour 24 hours ACE-2 acute respiratory syndrome aims Algorithms angiotensin angiotensin-converting enzyme 2 bulbar conjunctiva cathepsin cellular entry Conjunctiva Contamination contraindication contraindications Cornea Corneal Corneal Graft Corneal transplantation coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 crisis Ct value Culture culture media decrease diagnosed diagnosed with COVID-19 Donor Donor selection donors enzyme epithelial cell epithelial cells epithelium evaluate Evidence Ex vivo exacerbated exploration expresse expressed expression expression of SARS-CoV-2 expression pattern female genetic material healthy donor immunohistochemistry implication IMPROVE increase in Infection infectious dose inoculation involved lack limbus limited sample size mandatory media median moderate molecular mRNA level nasopharyngeal Nasopharyngeal swab nasopharyngeal swabs Not contaminated Ocular surface organ organ culture pandemic pathway Patient PCR positive Positive test Postinfection promote promoted Protein qPCR quantified quantitative PCR question RdRP receptor Replication researcher respiratory respond retrieved reverse transcription Reverse transcription quantitative PCR risk risk of transmission RNA RNA copy RNA sequence RT-qPCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 receptor SARS-CoV-2 receptors SARS-CoV-2 RNA SARS-CoV-2 viral SARS-CoV-2 virus Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significant increase Support TCID tested tissue tissue culture tissues TMPRSS2 Transmission utility Viral Viral detection Viral RNA was tested were infected worsened
[DOI] 10.1371/journal.pmed.1003922 PMC 바로가기 [Article Type] Research Article

SARS-CoV-2 Infection Triggers Phosphorylation: Potential Target for Anti-COVID-19 Therapeutics

SARS-CoV-2 감염은 인산화를 유발합니다: Anti-COVID-19 치료제의 잠재적 표적

Review

Published on 2022-02-172022-09-11
Journal: Frontiers in Immunology [Category] 치료기술, 치료제,

Profiling Selective Packaging of Host RNA and Viral RNA Modification in SARS-CoV-2 Viral Preparations

Cell and Developmental Biology

Published on 2022-02-032022-10-31
Journal: Frontiers in Cell and Developmental Biology [Category] COVID-19,

[키워드] Cell examined function genomic RNA Host host cells identify in viral isolate mechanism Modification modifications packaged packaging preparation Profiling RNA RNA sequencing RNAs SARS-CoV-2 SARS-CoV-2 viral selective SRP RNA the SARS-CoV-2 Transcriptome transcriptomic transfer RNA tRNA tRNAs uninfected VeroE6 cell viral life cycle viral-host interaction virion virus
[DOI] 10.3389/fcell.2022.768356 PMC 바로가기 [Article Type] Cell and Developmental Biology

Quantifying Neutralizing Antibodies in Patients with COVID-19 by a Two-Variable Generalized Additive Model

2변수 일반화 첨가제 모델을 통한 COVID-19 환자의 중화 항체 정량화

Research Article

Published on 2022-02-022022-09-10
Journal: mSphere [Category] COVID19(2023년), MERS, SARS, 바이오마커, 진단, 치료기술,

[키워드] “COVID-19 acute respiratory syndrome Additive Additive Model analyzed antibodies antibody Antibody binding Antibody titer Antibody titers approach binding binding affinity Biology biosafety biosafety level certification Clinical use Combination conventional virus neutralization test coronavirus correlation CoV COVID-19 detect disease domain Efficacy ELISA enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay faster Generalized gold gold standard healthy donors Immunity Laboratory level 2 mathematics methodology Model neutralization test Neutralizing antibodies neutralizing antibody Neutralizing antibody titer neutralizing antibody titers Patient patients with COVID-19 PCR-confirmed Perspective platform predicted RBD Receptor-binding domain reflected regions risk SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 viral Serological testing serum Severe acute respiratory syndrome Severe Acute Respiratory Syndrome CoV specimens Spike protein surrogate the binding affinity the RBD time-consuming Travel two-variable generalized additive model Vaccine vaccine efficacy Viral viral spike protein virus neutralization test with COVID-19
[DOI] 10.1128/msphere.00883-21 PMC 바로가기 [Article Type] Research Article