selection pressure – Page 6 – Communicable Diseases Research

Genetic grouping of SARS-CoV-2 coronavirus sequences using informative subtype markers for pandemic spread visualization

전염병 확산 시각화를 위한 유익한 하위 유형 마커를 사용한 SARS-CoV-2 코로나바이러스 서열의 유전적 그룹화

Research Article

Published on 2020-09-172022-08-13
Journal: PLoS Computational Biology [Category] SARS, 유전자 메커니즘,

[키워드] added addition Analysis Applying Asia Author base cause Clustering complementary confirmed case Containment strategy COVID-19 COVID-19 pandemic D614G detect disease spread distribution downstream analyses effective efficient epidemiological studies Epidemiological study Europe followed by founder effect Frequency frequency analysis generate Genetic Genetic variant genetic variants Geographic distribution GISAID GISAID database Github highlight identify include increasingly individuals infected individual infected individuals information Local Major marker modeling Mutation New York Nextstrain Novel coronavirus nucleotide nucleotides ORF1ab outbreak pandemic Phylogenetic prevalent researcher responsible SARS-CoV-2 SARS-CoV-2 coronavirus SARS-CoV-2 evolution SARS-CoV-2 pandemic SARS-CoV-2 sequence SARS-CoV-2 sequences selection pressure sequence sequenced spatiotemporal Spike protein Spread subtype Subtypes temporal dynamics the spike protein the United State The United States therapeutic threshold United States utility Vaccine variant Viral viral dynamics viral genome viral genomes Viral transmission virus Visualization website
[DOI] 10.1371/journal.pcbi.1008269 PMC 바로가기 [Article Type] Research Article

Adaptive Evolution of Feline Coronavirus Genes Based on Selection Analysis

Research Article

Published on 2020-08-132022-10-27
Journal: BioMed Research International [Category] Coronavirus, MERS,

Analysis of codon usage of severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) and its adaptability in dog

Article

Published on 2020-08-072022-11-01
Journal: Virus research [Category] COVID-19, MERS, SARS,

Polymorphism and Selection Pressure of SARS-CoV-2 Vaccine and Diagnostic Antigens: Implications for Immune Evasion and Serologic Diagnostic Performance

Article

Published on 2020-07-172022-10-28
Journal: Pathogens [Category] COVID-19,

An Africa-wide genomic evolution of insecticide resistance in the malaria vector Anopheles funestus involves selective sweeps, copy number variations, gene conversion and transposons

말라리아 매개체 Anopheles funestus의 살충제 저항성의 아프리카 전역 게놈 진화에는 선택적 스윕, 복제 수 변이, 유전자 전환 및 트랜스포존이 포함됩니다

Research Article

Published on 2020-06-042022-09-06
Journal: PLoS Genetics [Category] Communicable Disease, 말라리아,

[키워드] alleles Analysis Anophele approach bed net complex copy number cytochrome P450 driven by Effectiveness Evidence evidence of Evolution exhibited gene conversion gene flow Genes genetic diversity genomic genomic change genomic region glutathione greater haplotypes highlighting independent insecticide insecticides insertion Intervention Local loci locus malaria malaria control malaria vector management metabolic Metabolic resistance molecular molecular evolution Multiple performed Population pyrethroid respond risk selection pressure selective sweep selective sweeps signature Spread Temporal transposon Variation variations vector control whole genome
[DOI] 10.1371/journal.pgen.1008822 PMC 바로가기 [Article Type] Research Article

SARS‐CoV‐2, an evolutionary perspective of interaction with human ACE2 reveals undiscovered amino acids necessary for complex stability

Original Article

Published on 2020-05-072022-10-31
Journal: Evolutionary Applications [Category] COVID-19,

[키워드] ACE2 Amino acid Analysis Betacoronavirus betacoronavirus spike protein binding cell receptor complex conserved coronavirus Critical death determine directional effective ENhance evolutionary dynamics Factor FIVE genomic region glycine hACE2 host cells human ACE2 human cell human cells human host implicated IMPROVE infect Infection infections inhibiting binding Interaction modeling molecular dynamics performed Perspective Positive selection predict purifying selection receptor receptor ACE2 receptor‐binding domain residue reveal Salt Bridge SARS‐CoV‐2 SARS‐CoV‐2 selection pressure spike glycoprotein Spike protein stability viral evolution viral lineages viral spike protein virus
[DOI] 10.1111/eva.12980 PMC 바로가기 [Article Type] Original Article

Genetic Analysis of Avian Coronavirus Infectious Bronchitis Virus in Yellow Chickens in Southern China over the Past Decade: Revealing the Changes of Genetic Diversity, Dominant Genotypes, and Selection Pressure

Article

Published on 2019-09-262022-10-28
Journal: Viruses [Category] Coronavirus,

Analysis of Nipah Virus Codon Usage and Adaptation to Hosts

Original Research

Published on 2019-05-082023-08-30
Journal: Frontiers in Microbiology [Category] E형 간염,

[키워드] CAI codon usage compositional constraint Nipah virus RCDI selection pressure similarity index
[DOI] 10.3389/fmicb.2019.00886 PMC 바로가기 [Article Type] Original Research

Asymmetric evolution in viral overlapping genes is a source of selective protein adaptation

Article

Published on 2019-04-032023-08-30
Journal: Virology [Category] E형 간염,

[키워드] De novo frame Ancestral frame homologs Non-synonymous nucleotide substitution selection pressure Synonymous nucleotide substitution virus adaptation
[DOI] 10.1016/j.virol.2019.03.017 PMC 바로가기 [Article Type] Article

Genetic ancestry and population differences in levels of inflammatory cytokines in women: Role for evolutionary selection and environmental factors

여성의 염증성 사이토카인 수치의 유전적 조상과 집단 차이: 진화적 선택과 환경적 요인의 역할

Research Article

Published on 2018-06-072022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] accumulated adaptive African age alcohol allele Analysis ancestry Antigen antigen receptor Blood cells CCL11 CCL2 chemokine chemokines chronic inflammation circulating circulating cytokines cytokine Cytokines Diseases Endemic environmental factor eosinophils European examined explain exposure to Factor Factors finding gene encoding Genetic genetic difference genetic differences Genetic variant Genetic variation Health Human human immunity IFNα2 IL10 IL1RA IL4 immune immune response immune response genes immune system Immunity implicated implication individual Infection Inflammation Inflammatory Inflammatory cytokine innate and adaptive immunity involved Level living environment living environments Local malaria Migration molecular monocyte Monocytes obesity occur Part pathogen Pathogens phenotypic variance plasma Plasma levels populations pro-inflammatory Protein receptor protein red blood cells Regulation role Selection selection pressure signal significant difference significant differences smoking susceptibility systemic level thought variant Variation White blood cells women
[DOI] 10.1371/journal.pgen.1007368 PMC 바로가기 [Article Type] Research Article