Implementation of new ECMO centers during the COVID-19 pandemic: experience and results from the Middle East and IndiaObservational Study Published on 2021-08-012022-10-05 Journal: Intensive care medicine [Category] SARS, 임상, [키워드] 95% CI Analysis Cardiopulmonary conducted country Course COVID-19 COVID-19 patient Data collection demographic data discharge ECMO Epidemiology evaluate Extracorporeal FIVE Hypoxemia India inotrope International interquartile range IQR less male median age membrane men Middle East Mortality multicenter New Odds ratio outcome outcomes Oxygenation pandemic Pandemics Patient patients treated patients with COVID-19 PEEP Primary outcome prone positioning resource respiratory acidosis retained retrieved retrospective SARS-CoV2 secondary selected Seven severe coronavirus disease SOFA score stratified study period Support survival SWAAC-ELSO. treated Treatment [DOI] 10.1007/s00134-021-06451-w PMC 바로가기 [Article Type] Observational Study
Discontinuation versus continuation of renin-angiotensin-system inhibitors in COVID-19 (ACEI-COVID): a prospective, parallel group, randomised, controlled, open-label trialRandomized Controlled Trial Published on 2021-08-012022-10-05 Journal: The Lancet. Respiratory Medicine [Category] SARS, 유전자 메커니즘, 임상, [키워드] 1:1 ACEi ACEIs Admission angiotensin-converting enzyme 2 ARBs assigned AUC blocker cardiovascular center Course COVID-19 dead death died eight Endpoint enrolled faster females Germany had no human cell Hypothesis inhibitor intensive care mechanical ventilation median median age mitigate modified intention-to-treat no significant difference Older Open-label organ dysfunction Organ failure outcome parallel group Patient patients died randomised Randomly RAS receptor Registered renin-angiotensin system risk SARS-CoV-2 entry Science scored secondary severity of COVID-19 significant effect significantly lower SOFA SOFA score symptomatic SARS-CoV-2 infection the primary endpoint therapy treated Treatment Trial upregulated [DOI] 10.1016/S2213-2600(21)00214-9 PMC 바로가기 [Article Type] Randomized Controlled Trial
Differences in Inflammatory Marker Kinetics between the First and Second Wave of COVID-19 Patients Admitted to the ICU: A Retrospective, Single-Center StudyArticle Published on 2021-07-262022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 113 patient Admission C-reactive protein collected Comorbidities Complication Corticosteroid COVID-19 COVID-19 pandemic CRP Day demographics determine difference dysfunction enrolled evaluated ferritin level greater ICU ICU patient ICU Patients immunomodulation Immunomodulatory therapies immunomodulatory therapy Inflammatory response Kinetics Laboratory results management Patient PCT procalcitonin reduced retrospective second second wave significantly significantly lower single-center SOFA score steroid was measured Wave WBC White blood cell widespread [DOI] 10.3390/jcm10153290 PMC 바로가기 [Article Type] Article
Mortality and Clinical Interventions in Critically ill Patient With Coronavirus Disease 2019: A Systematic Review and Meta-AnalysisMedicine Published on 2021-07-232022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% CI Abstract America APACHE II score article Biology Care case sery Characteristics China clinical clinical interventions cohort study COVID-19 Critical Critically ill patient critically ill patients duplicates Effectiveness eliminating Europe evaluate Evidence help heterogeneity hospital Hospitalization ICU identify inclusion criteria Infrastructure intensive care Invasive mechanical ventilation kidney Medicine Meta-analysis Middle East Mortality Older age outcome PaO participant Patient Primary outcome review screened searched secondary outcome SOFA score subgroup analysis Support supportive care surviving patients systematic review therapy those who survived Web of Science were used with COVID-19 [DOI] 10.3389/fmed.2021.635560 PMC 바로가기 [Article Type] Medicine
Prediction of 28-day mortality in critically ill patients with COVID-19: Development and internal validation of a clinical prediction modelResearch Article Published on 2021-07-132022-10-28 Journal: PLoS ONE [Category] COVID-19, [키워드] 28-day mortality Admission admitted to ICU age bootstrap C-statistic Cohort Comorbidity COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients critical COVID-19 patients Critically ill Critically ill patient death develop development diabete diagnosis of SARS-CoV-2 died disease evaluate evaluated expected Factors Hospitalization ICU admission ICUs independent predictor intensive care unit internal IQR Laboratory mandatory material Mortality multivariable multivariable Cox regression multivariable model obesity PaO paO2/fiO2 Patient Pneumonia prediction Predictive Probability procalcitonin prognostic model required Result SOFA SOFA score the median variables was performed [DOI] 10.1371/journal.pone.0254550 PMC 바로가기 [Article Type] Research Article
High Mobility Group Box 1 and Interleukin 6 at Intensive Care Unit Admission as Biomarkers in Critically Ill COVID-19 Patients중환자 단위에서 고도리 그룹 박스 1 및 인터루킨 6은 중환자 실에 입원하여 중환자가 아픈 Covid-19 환자에서 바이오 마커로Articles Published on 2021-07-032022-09-10 Journal: The American Journal of Tropical Medicine and Hygi [Category] SARS, 바이오마커, [키워드] “cytokine storm” Accuracy Acute kidney injury Admission age Analysis analyzed assessment Biomarkers Box C-reactive protein Comorbidities Comorbidity comparable coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 patients COVID-GRAM Critically ill critically ill COVID-19 patients Cytokine storm D-dimer levels discharge elevated enrolled Exuberant failure Gender group healthy control HMGB1 ICU ICU admission ICU patient IL-6 IL-6 level IL-6 levels IL6 Ill Inflammation intensive care intensive care unit interleukin interleukin 6 interleukin-6 investigated Mobility Mortality neutrophil nonsurvivor PaO Pathogenesis Patient plasma Plasma HMGB1 Plasma levels poor oxygenation predicted prognostic prognostic biomarker Prognostic biomarkers Prognostic markers prospective cohort study risk Septic shock severe coronavirus disease severe COVID-19 SOFA SOFA score suggested Survivors Ventilation with COVID-19 [DOI] 10.4269/ajtmh.21-0165 PMC 바로가기 [Article Type] Articles
Risk factors for mortality in critically ill patients with COVID-19: a multicenter retrospective case-control studyResearch Article Published on 2021-06-242022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, SARS, [키워드] 95% CI Admission Analysis APACHE II APACHE II score assessment being case-control study chronic Clinical data collected confidence Coronavirus disease 2019 COVID-19 COVID-19 patients Critically ill Critically ill patient CRP death death case declining determine enrolled Factor failure hazard ratio identify IL-6 In-hospital death Increasing independent risk factor Inflammation Inpatient interval likelihood Lymphocyte count lymphopenia Mortality multicenter multivariable Cox regression Organ failure paO2/fiO2 Patient patients Physiology poor prognosis positive Result retrospective risk factor Risk factors SARS-CoV-2 SOFA SOFA score Spread supplementary material survival univariable with COVID-19 [DOI] 10.1186/s12879-021-06300-7 PMC 바로가기 [Article Type] Research Article
Acute Kidney Injury Due to COVID-19 in Intensive Care Unit: An Analysis From a Latin-American CenterMedicine Published on 2021-06-042022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Acute kidney injury affected age AKI AKI patient analyzed Anemia center Continuous renal replacement therapy coronavirus COVID-19 COVID-19 patient COVID-19 patients death diabete Diabetic diagnosed dialysis evaluate hypertension ICU independent risk factor Inflammatory marker intensive care intensive care unit kidney Latin America Logistic regression lymphopenia male mechanical ventilation median medical record Mortality Older organ support Patient patients required risk risk factor SARS-CoV-2 SOFA score Survivors Therapies workup [DOI] 10.3389/fmed.2021.620050 PMC 바로가기 [Article Type] Medicine
Risk Stratification for ECMO Requirement in COVID-19 ICU Patients Using Quantitative Imaging Features in CT Scans on AdmissionArticle Published on 2021-06-032022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] 95% CI Admission affected age Analysis artificial intelligence AUC BMI body mass index can be used Computed tomography computed tomography scan Coronavirus disease 2019 COVID-19 COVID-19 patient CT finding CT scan diagnostic ECMO ECMO therapy evaluated Extracorporeal extracorporeal membrane oxygenation feature hospital Hospital admission ICU ICU admission ICUs imaging IMPROVE include intensive care unit IQR Lactate Logistic regression lung lung involvement management median time membrane Organ failure Oxygenation parameter Patient patient data predict receiver operating characteristic Requirement resource Respiratory distress syndrome risk stratification ROC sensitivity severe COVID-19 disease Sex significantly significantly higher significantly lower single-center study SOFA SOFA score specificity subsequent therapy Treatment [DOI] 10.3390/diagnostics11061029 PMC 바로가기 [Article Type] Article
Epidemiology and Mycology of Candidaemia in non-oncological medical intensive care unit patients in a tertiary center in the United States: Overall analysis and comparison between non-COVID-19 and COVID-19 cases미국 3차 센터의 비종양내과 중환자실 환자의 칸디다혈증 역학 및 균류: 비COVID-19 및 COVID-19 사례 간의 종합 분석 및 비교Article Published on 2021-06-012022-09-11 Journal: Mycoses [Category] SARS, 치료기술, [키워드] accounted Admissions analysed Analysis Candida albicans Candidaemia candidiasis Central venous catheter Characteristics coronavirus COVID-19 COVID-19 case COVID-19 group COVID-19 patient COVID-19 patients Critical care Critically ill Critically ill patient critically ill patients determine disease distribution Epidemiology globe ICU ICU admission ICUs identify incidence intensive care invasive invasive candidiasis isolates less medical icu medical intensive care unit mycology mycology. Non-COVID-19 non-COVID-19 and COVID-19 patients non-COVID-19 group non-COVID-19 patient Non-COVID-19 patients occurred pandemic Patient provide SARS-CoV-2 pandemic SOFA score the patient the SARS-CoV-2 the United State United States venous catheter [DOI] 10.1111/myc.13258 PMC 바로가기 [Article Type] Article