A selective sweep in the Spike gene has driven SARS-CoV-2 human adaptation
Spike 유전자의 선택적 스윕은 SARS-CoV-2 인간 적응을 주도했습니다
Article
[키워드] acute respiratory syndrome
acute respiratory syndrome coronavirus
acute respiratory syndrome coronavirus 2
adaptive
assays
bat
bats
binding
cellular receptor
contributed
coronavirus
coronavirus disease
Coronavirus disease 2019
COVID-19
D614G
D614G mutation
domain
emergence
Evolution
Genome
glycosylation
greater
hACE2
higher affinity
hosts
human ACE2
human lung cell
human lung cells
human SARS-CoV-2
human-to-human transmission
molecular
molecular virology
mutant
Mutation
Non-synonymous
pandemic
pangolins
Positive selection
predicted
RBD
related virus
Replication
reservoir
SARS-CoV-2
selective
selective sweep
sequence
severe acute respiratory syndrome Coronavirus
Spike protein
spillover
sustained
the Spike
the spike protein
Transmission
variant
viral adaptation
wild-type
[DOI] 10.1016/j.cell.2021.07.007 PMC 바로가기 [Article Type] Article
[DOI] 10.1016/j.cell.2021.07.007 PMC 바로가기 [Article Type] Article