Effects of mild obesity on outcomes in Japanese patients with COVID-19: a nationwide consortium to investigate COVID-19 host genetics Research Published on 2022-08-092022-10-05 Journal: Nutrition & Diabetes [Category] SARS, 바이오마커, 유전자 메커니즘, 치료법, [키워드] adjusted adjusted odds ratio Analysis analyzed benefit BMI body mass index class coronavirus disease COVID-19 COVID-19 patient Critical Critical case critical cases defined died disease severity Effect enrolled force host genetics independent risk factor indicated intensive care Invasive mechanical ventilation Japan Japanese Mild mortality rate multiple logistic regression no difference obesity Odds ratio outcome Oxygen administration Oxygenation Patient patients with COVID-19 reported required Respiratory failure Result risk risk factor severe COVID-19 severe disease severity of COVID-19 stratified the patient treated [DOI] 10.1038/s41387-022-00217-z [Article Type] Research
Underuse of primary healthcare in France during the COVID-19 epidemic in 2020 according to individual characteristics: a national observational studyObservational Study Published on 2022-08-092022-10-05 Journal: BMC primary care [Category] 임상, [키워드] age ambulatory Ambulatory healthcare use Analysis Care changed children chronic chronic disease Chronic diseases COVID-19 COVID-19 epidemic COVID-19 pandemic database deaths decrease dentist Deprivation disease Epidemic epidemic trends France Health healthcare Healthcare system increase in increasing age individual lockdown morbidity and mortality National Nurse observational study Patient performed Physiotherapist primary care psychiatrists screening tests Sex significantly stratified the mean [DOI] 10.1186/s12875-022-01792-x PMC 바로가기 [Article Type] Observational Study
Evaluation of serological response to anti-SARS-CoV-2 mRNA vaccination in hematological patients혈액학적 환자에서 anti-SARS-CoV-2 mRNA 백신접종에 대한 혈청학적 반응 평가Article Published on 2022-08-082022-09-12 Journal: Frontiers in Immunology [Category] SARS, 진단, [키워드] Administered anti-SARS-CoV-2 anti-SARS-CoV-2 IgG anti-SARS-CoV-2 vaccination Anti-spike anti-Spike IgG anti-spike IgG level antibody Antibody titer association Cell Cohort cohort of patient Concentration control arm control group Cutoff demographic variable difference drug Effect evaluated greater health worker healthy healthy subjects hematological Hematological malignancies Hematological malignancy heterogeneous highest identify IgG IgG titer immune system immunoassay Immunocompromised patients Immunosuppression implication inhibitor Italy leukemia Microparticle molecular mRNA mRNA vaccination mRNA vaccine onco-hematology. parameter pathology Patient patients performed Predictive reached reduced reported SARS-CoV-2 SARS-CoV-2 antibody second dose seroconversion rate serological response shown significantly lower spike IgG statistical significance steroid stratified Surveillance the mean the patient Therapies therapy treated tyrosine underlying disease vaccination Vaccine was reduced [DOI] 10.3389/fimmu.2022.892331 PMC 바로가기 [Article Type] Article
Preterm birth among pregnant persons with severe acute respiratory syndrome Coronavirus 2 infection Research Published on 2022-08-042022-10-05 Journal: Journal of perinatology : official journal of the [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome adjusted age analyzed asymptomatic infection calculated can be used Clinical practice complications coronavirus 2 COVID-19 Critical examined Illness severity increased risk Infection Medical conditions Mild moderate-to-severe COVID-19 objective Pregnancy pregnant Preterm birth Result risk risk ratio SARS-COV-2 infection selected stratified The United States vaccination [DOI] 10.1038/s41372-022-01467-6 [Article Type] Research
Independent predictors of in-hospital mortality and the need for intensive care in hospitalized non-critical COVID-19 patients: a prospective cohort studyObservational Study Published on 2022-08-012022-10-04 Journal: Internal and Emergency Medicine [Category] COVID19(2023년), SARS, 임상, [키워드] active cancer Admission albumin albumin level Analysis baseline blood test Blood urea nitrogen build Care Characteristics classical clinical feature condition confidence interval coronavirus COVID-19 death demographic data demographics died evaluate Factor Features Hospitalized hospitalized patient ICU ICU care in-hospital mortality independent independent predictors infected with SARS-CoV-2 intensive care intensive care unit laboratory parameter Male sex Older age outcome Pandemics Patient performed predict Predictive predictor Probability prospective cohort study receiver recruited risk ROC SARS-CoV-2 significant variables single-center study sodium Sodium. Stratification stratified tested the patient underlying disease urea [DOI] 10.1007/s11739-022-02962-6 PMC 바로가기 [Article Type] Observational Study
Pharmacogenetic variants and risk of remdesivir-associated liver enzyme elevations in Million Veteran Program participants hospitalized with COVID-19COVID-19로 입원한 백만 재향 군인 프로그램 참가자의 약물 유전적 변이 및 렘데시비르 관련 간 효소 상승 위험Article Published on 2022-08-012022-09-11 Journal: Clinical and translational science [Category] COVID19(2023년), SARS, 변종, [키워드] adjusted administration age Alanine alanine aminotransferase ALT assigned association baseline black Comorbidities components conducted coronavirus disease Coronavirus disease 2019 COVID-19 CYP2C19 drug Drug administration Elevation enzyme food Hospitalized Linear regression liver enzyme liver enzymes log-transformed Million Veteran Program multifactorial multivariable model participant Participants Patient pharmacogenetic phenotype receiving Remdesivir retrospective risk Sex stratified Treatment treatment initiation variant was performed white with COVID-19 [DOI] 10.1111/cts.13313 PMC 바로가기 [Article Type] Article
The impact of COVID-19 pandemic on individuals at clinical high-risk for psychosis: Evidence from eye-tracking measuresResearch article Published on 2022-08-012022-10-05 Journal: Progress in neuro-psychopharmacology & biological [Category] 바이오마커, 임상, [키워드] abnormality Accuracy amplitude Biomarker caused Characteristics checklist Clinical high-risk for psychosis Clinical symptoms COVID-19 COVID-19 pandemic distress DSM-5 Effect Evidence eye Eye movement fixation healthy healthy control high risk Impact individual individuals information investigated measure Mental disorder negatively affected Pandemics participant Participants Perceived Stress Scale physiological post-traumatic provide PSS-10 Psychological distress PTSD reported saccade scale severity significantly significantly higher stability stratified Stress subgroups suggested Symptom the mean total score were assessed were measured [DOI] 10.1016/j.pnpbp.2022.110578 [Article Type] Research article
Characteristics of procalcitonin in hospitalized COVID-19 patients and clinical outcomes of antibiotic use stratified by procalcitonin levels입원한 코로나19 환자에서 프로칼시토닌의 특성과 프로칼시토닌 수치로 계층화된 항생제 사용의 임상적 결과Article Published on 2022-08-012022-09-11 Journal: Internal and Emergency Medicine [Category] 바이오마커, [키워드] antibiotic antibiotic use Antibiotics Bacterial bacterial co-infection baseline characteristics Characteristics clinical Clinical outcome clinical outcomes Cohort COVID-19 COVID-19 patient COVID-19 severity Critically ill Cutoff disease do not intubate do not resuscitate elevated examined excluded Factor group hospital hospitalized COVID-19 patient hospitalized COVID-19 patients ICU ICU patient Infection intensive care mechanical ventilation median microbiologically non-critically ill patient non-critically ill patients non-ICU NPV oxygen Oxygen requirement Patient PCT performed PPV pro-calcitonin procalcitonin procalcitonin level renal renal disease retrospective review significantly significantly higher status stratified Tocilizumab use of antibiotics utility [DOI] 10.1007/s11739-022-02955-5 PMC 바로가기 [Article Type] Article
Risk Stratification Models for Stroke in Patients Hospitalized with COVID-19 InfectionResearch article Published on 2022-08-012022-10-05 Journal: Journal of stroke and cerebrovascular diseases : t [Category] 바이오마커, [키워드] 95% CI Admission adults hospitalized afebrile AHA assigned build C-statistic c-statistics cardiovascular Cerebrovascular disease coefficient Comorbidities covariates COVID-19 Cox regression cross demographics elevated Factor generate groups help high risk hypertension identify Intracerebral hemorrhage Laboratory Leukocytosis machine material medications medium Model multivariable analyses objective outcome patients hospitalized patients with COVID-19 pulmonary disease registry Result risk Risk-stratification second stratified stroke Systolic blood pressure temperature thrombosis univariable used data with COVID-19 [DOI] 10.1016/j.jstrokecerebrovasdis.2022.106589 [Article Type] Research article
Utility of Newborn Dried Blood Spots to Ascertain Seroprevalence of SARS-CoV-2 Antibodies Among Individuals Giving Birth in New York State, November 2019 to November 20212019년 11월부터 2021년 11월까지 뉴욕주에서 출생한 개인들 사이에서 SARS-CoV-2 항체의 혈청유병성을 확인하기 위한 신생아 건조 혈액 반점의 유용성Article Published on 2022-08-012022-09-11 Journal: JAMA Network Open [Category] SARS, 진단, 치료기술, [키워드] 95% CI age analyzed association Birth Birth weight Blood can be used Characteristics collected conducted correlated COVID-19 COVID-19 case COVID-19 vaccination cross-sectional cross-sectional study cumulative DBS sample detect Dried blood spots exposure to female fluctuation gestational age Giving identify IgG antibodies IgG antibody immunoassay individual individuals Infant Infants Low birth weight Lower male maternal age median microsphere MONITOR Multiple birth New York Newborn Odds ratio Older outcome pregnant Prevalence Program reflected repeated reported S antigen SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 N SARS-CoV-2 nucleocapsid SARS-CoV-2 seroprevalence Screening screening program Seroprevalence Serosurvey Serosurveys significantly lower spot state stratified study period submitted utility vaccination Vaccinations was measured women [DOI] 10.1001/jamanetworkopen.2022.27995 PMC 바로가기 [Article Type] Article